Reaction kinetics of trioxane synthesis from formaldehyde catalyzed by sulfuric acid/ionic liquid was written by Xie, Hui;Lv, Li;Zhang, Tao;Tang, Shengwei. And the article was included in Reaction Kinetics, Mechanisms and Catalysis in 2021.Electric Literature of C10H20N2O4S The following contents are mentioned in the article:
The composite catalyst composed of sulfuric acid and alkyl imidazole-based acidic ionic liquid was used to replace pure sulfuric acid as the catalyst for the synthesis of trioxane. 1-ethyl-3-methylimidazolium hydrosulfate ([EMIM][HSO4]), 1-butyl-3-methylimidazolium hydrosulfate ([BMIM][HSO4]), and 1-hexyl-3-methylimidazole hydrosulfate ([HMIM][HSO4]) were chosen to form composite catalysts with sulfuric acid. The effects of ionic liquid types, formaldehyde concentration (35 鈭?55 wt%), and temperature (353 鈭?368 K) on the reaction were studied. When H2SO4 / [EMIM][HSO4] was used as catalyst with a dosage of 0.6 mol/kg of formaldehyde solution, the optimal catalytic performance was obtained at 373 K with the 50 wt% formaldehyde solution as initial reactant. Compared to that with pure H2SO4 as the catalyst, the trioxane concentration in the reaction system was sharply increased with an increment of 17% by the synergy of ionic liquid [EMIM][HSO4]. The equilibrium constant was increased from 3.08 x 10-5 to 4.19 x 10-5 by the addition of [EMIM][HSO4]. The reaction was intensified by the inhibition of reverse reaction. It indicates that the addition of [EMIM][HSO4] has complicated effects on the reaction. The research results provide a deep understand for the catalytic performance of mineral acid/ionic liquid composite catalysts. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Electric Literature of C10H20N2O4S).
1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Electric Literature of C10H20N2O4S
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem