Category: 478935-29-4

Biginelli reaction starting directly from alcohols was written by Garima;Srivastava, Vishnu P.;Yadav, Lal Dhar S.. And the article was included in Tetrahedron Letters in 2010.Computed Properties of C10H20N2O4S The following contents are mentioned in the article:

An efficient of one-pot oxidative access to 3,4-dihydropyrimidin-2-(1H)-ones directly from aromatic alcs. under mild conditions is reported. The protocol involves 1-methylimidazolium hydrogen sulfate [Hmim]HSO₄ catalyzed oxidation of aromatic alcs. to aromatic aldehydes with NaNO₃ followed by their cyclocondensation with 1,3-dicarbonyl compounds and urea in the same reaction vessel at 80 °C within 2-4 h to afford 3,4-dihydropyrimidin-2-(1H)-ones in 55-97% overall yields. Thus, the present work utilizing alcs. instead of aldehyde in Biginelli reaction is a valid and green alternative to the classical synthesis of 3,4-dihydropyrimidin-2-(1H)-ones. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Computed Properties of C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Computed Properties of C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of aethylparabenum catalyzed by task-specific acidic ionic liquid was written by Tan, Feng;Hu, Rong;Yang, Xue-jun;Li, Jun-yang. And the article was included in Xinan Minzu Daxue Xuebao, Ziran Kexueban in 2008.COA of Formula: C10H20N2O4S The following contents are mentioned in the article:

P-hydroxybenzoic acid and anhydrous ethanol are used to synthesize aethylparabenum with novel Bronsted activated [Hmim]HSO₄ as the catalyst. The influences of the reaction period, the mole ratio between alc. and acid, and the amount of ionic fluid on the ester yield were investigated. The optimized reaction condition is confirmed, according to which the reaction period should be 2.5 h, the mole ratio between alc. and acid should be 1:1.5, and the amount of ionic fluid should be 3 mL. Under this optimized condition, the ester yield could achieve 81.5%, and the ionic fluid could be used for 5 times repeatedly without any change of its catalytic efficiency. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4COA of Formula: C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).COA of Formula: C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Indirect electrochemistry oxidation of alcohol to aldehyde in ionic liquid was written by Zhao, Xin-hua;Jiang, Xiao-min;Xie, Jiao. And the article was included in Guangzhou Huagong in 2013.Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate The following contents are mentioned in the article:

The indirect electrochem. oxidation of alc. could be carried out in the protonic ionic liquid methylimidazolium hydrogen sulfate with high selectivity-and current efficiency. The reaction consumed alc. and produced the corresponding aldehyde with the co-product of hydrogen gas in the electrochem. oxidation of alc. Further more, the corresponding carbonyl products could be separated from the electrolyte solution by the refluxing method, and the electrolyte solution could be recycled without apparent decrease in activity. Thus, this approach avoided the problematic by products and separation difficulty in the preparation of the short chain aliphatic aldehydes. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Preparation of imidazolium ionic liquids and their catalytic activity in the synthesis of β-enaminones was written by Yin, Wanxiang;Li, Runsheng;Long, Yulin;Li, Ming;Yang, Jun. And the article was included in Jinan Daxue Xuebao, Ziran Kexue Yu Yixueban in 2010.Recommanded Product: 478935-29-4 The following contents are mentioned in the article:

A series of imidazolium ionic liquids ([Hmim]⁺) with different anions were prepared and the catalytic performance of these catalysts for the synthesis of β-enaminones were investigated. The results showed that these [Hmim]⁺-type ionic liquids exhibited excellent activity; [Hmim]BF₄ had the best catalytic performance and had a yield of 96% after 10 min. [Hmim]BF₄ as a catalyst has been used for the synthesis of different β-enaminones and most of the reactions can proceed smoothly. [Hmim]BF₄ was reused five times without considerable loss of activity and had a yield of 89% after 10 min reaction. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Recommanded Product: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Recommanded Product: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Clean synthesis of adipic acid by catalytic oxidation of cyclohexene in acidic ionic liquid was written by Wang, Xiaodan;Cui, Tianfang;Yu, Xiulan. And the article was included in Shenyang Huagong Daxue Xuebao in 2012.Related Products of 478935-29-4 The following contents are mentioned in the article:

Without any organic solvent and halide, oxidation of cyclohexene to adipic acid with aqueous 30% hydrogen peroxide catalyzed by tungstic acid/acidic ionic liquids was carried out. When the molar ratio of cyclohexene, tungstic acid, N-methylimidazolium hydrosulfate ([HMM]HSO₄) and hydrogen peroxide was 50:1:5:220 ([HMM]HSO₄, 10 mmol), the isolated yield of adipic acid could reach 90.5% for 7.5 h under reflux temperature Such yield was the same or better than that obtained from the present research. The catalyst was cheap, easily prepared and environment friendly, and it could be recycled easily with no loss of the activity. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Related Products of 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Related Products of 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of 1,5-benzodiazepine derivatives catalyzed by acidic ionic liquid was written by Xu, Qiu-yan;Ji, Shun-jun;Gu, Da-gong. And the article was included in Hecheng Huaxue in 2005.HPLC of Formula: 478935-29-4 The following contents are mentioned in the article:

A novel method was reported that 1,5-benzodiazepine derivatives were synthesized via the condensation of o-phenylenediamines with ketones using acidic ionic liquid and alc. as a catalyst system. Target compounds thus prepared included 2,3-Dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine, 2-ethyl-2,3-dihydro-2,3,4-trimethyl-1H-1,5-benzodiazepine, 2,3,9,10a-tetrahydrospiro[benzo[b]cyclopenta[e][1,4]diazepine-10(1H),1′-cyclopentane], etc. The ionic liquid used in this study was 1-he;yl-3-methyl-1H-imidazolium hydrogen sulfate. This catalyst system can be reused three times. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4HPLC of Formula: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.HPLC of Formula: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Catalytic synthesis of normal propyl cinnamate in acidic ionic liquid was written by Huang, Yanxian. And the article was included in Yingyong Huagong in 2012.Computed Properties of C10H20N2O4S The following contents are mentioned in the article:

Normal Pr cinnamate was synthesized with acidic ionic liquid[Hmim]HSO₄ as catalyst. The effects of molar ratio of acid/alc., reaction time and the catalyst amount of ionic liquid on the yield of Pr cinnamate were investigated and the optimal conditions were as follows: amount of cinnamic acid 1.48 g (0.01 mol), the molar ratio of acid to alc. 1:6, catalyst 2 mL, reaction time 5 h. The yield of the Pr cinnamate could reach 88.2%. The ionic liquid could be reused for 5 times without much lose in activities. The structure of Pr cinnamate was characterized by IR spectrum and chromatog./mass spectrometry. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Computed Properties of C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Computed Properties of C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Alkylation of isobutene and butane in acid ionic solution was written by Huang, Ying-lei;Yu, Chang-shun;Wang, Yan;Wang, Shao-jun. And the article was included in Dalian Gongye Daxue Xuebao in 2009.Related Products of 478935-29-4 The following contents are mentioned in the article:

Ionic liquids of [C₄ mim]HSO₄, [C₆mim]HSO₄ and [C₈mim]HS0₄ were synthesized by two-step method and used for alkylation of isobutene and butane. The effect of ionic liquids, temperature and catalyst on alkylation was studied. The best result was obtained when ionic liquids [C₆mim]HSO₄ was used as catalyst. The conversion rate with [C₆mim]HSO₄ as catalyst was 90% and the yield of alkylation was 89%, in which the optimum reaction time was 1 h and the amount of [C₆mim]HSO₄ was 6 g. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Related Products of 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Related Products of 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Novel one-pot facile synthesis of thiopyranopyrazole using [Hmim]HSO₄ catalyst was written by Srivastava, Vishal;Singh, Pravin K.;Singh, Praveen P.. And the article was included in Croatica Chemica Acta in 2014.Category: imidazoles-derivatives The following contents are mentioned in the article:

An efficient and easy protocol has been developed for synthesis of thiopyranopyrazoles I (R = 4-ClC₆H₄, 4-MeOC₆H₄, 4-BrC₆H₄, etc.) by using [Hmim]HSO₄ as recyclable catalyst under solvent-free condition at room temperature This environmentally benign method has advantages, such as high yield of products, simple work-up procedure, and avoidance of the organic solvents, which will contribute in serving as a green process greatly. The catalyst was easily recovered and reused without any considerable loss of activity. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Category: imidazoles-derivatives).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

One-pot oxidative conjugate hydrothiocyanation-hydrosulfenylation of Baylis-Hillman alcohols promoted by a protic ionic liquid was written by Yadav, Lal Dhar Singh;Patel, Rajesh;Srivastava, Vishnu Prabhakar. And the article was included in Synlett in 2008.Synthetic Route of C10H20N2O4S The following contents are mentioned in the article:

The first example of one-pot oxidative conjugate hydrothiocyanation-hydrosulfenylation of acrylic ester derived Baylis-Hillman alcs., i.e., Me 3-aryl-3-hydroxy-2-methylenepropanoate, was reported. The reaction involved protic ionic liquid [Hmim]HSO₄-mediated oxidation of Baylis-Hillman alcs. with NaNO₃ to give Me (E)-α-formylcinnamates followed by conjugate addition of sulfur-centered nucleophiles (NH₄SCN/PhSH) to afford the corresponding Me β-thiocyanato (or β-phenylsulfenyl)-α-formylhydrocinnamates diastereoselectively in 74-87% yields in a one-pot procedure. After isolation of the product, the ionic liquid [Hmim]HSO₄ could be easily recycled for further use without any loss of efficiency. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Synthetic Route of C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Synthetic Route of C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem