Category: 5036-48-6

On September 10, 2021, Liu, Ming; Jiang, Yufeng; Liu, Duanzijing; Wang, Junjie; Ren, Zhongjie; Russell, Thomas P.; Liu, Yao published an article.HPLC of Formula: 5036-48-6 The title of the article was Imidazole-Functionalized Imide Interlayers for High Performance Organic Solar Cells. And the article contained the following:

Imidazole-functionalized naphthalene diimide and perylene diimide were efficiently synthesized at low cost and used as versatile cathode interlayers in organic solar cells. These imidazole-functionalized small mols. show high electron affinity and conductivity and efficiently reduce the work function of air-stable metal electrodes, removing the energy barriers of electron transport in organic electronic devices. Compared to widely used amine-functionalized small-mol. cathode interlayers, the crystallinities of imidazole-functionalized mols. were moderately suppressed, affording good film-forming properties. The substitution of amine with the imidazole group is a simple and powerful strategy to improve both film morphol. and charge transport of imide-based small-mol. interlayer materials. The imidazole-functionalized interlayers are compatible with numerous active layers in solar cells, affording high efficiencies over a wide thickness range from ~5 nm to ~33 nm, with a maximum efficiency of 17.98%, showing promising applications in organic electronics. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).HPLC of Formula: 5036-48-6

The Article related to imidazole functionalized imide interlayer solar cell, Electrochemical, Radiational, and Thermal Energy Technology: Energy-Conversion Devices and Their Components and other aspects.HPLC of Formula: 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On July 15, 2020, Al-Otaibi, Jamelah S.; Almuqrin, Aljawhara H.; Mary, Y. Sheena; Thomas, Renjith published an article.Safety of N-(3-Aminopropyl)-imidazole The title of the article was Modeling the conformational preference, spectroscopic properties, UV light harvesting efficiency, biological receptor inhibitory ability and other physico-chemical properties of five imidazole derivatives using quantum mechanical and molecular mechanics tools. And the article contained the following:

Five imidazole derivatives, 1-Boc-imidazole (B1), 1-(trifluoroacetyl)imidazole (B2), 1-(2-hydroxyethyl)imidazole (B3), 1-(aminopropyl)imidazole (B4) and 1-ethylimidazole (B5) were analyzed for the structural, nonlinear optical, electronic and biol. properties. The functional nature of the compounds were analyzed using vibrational spectra and Raman spectra and was compared with the scaled, simulated spectra obtained using the d. functional theory using appropriate functional and basis set with diffuse orbitals and are found to be in close agreement. Relaxed potential energy scan predicts the stable conformers. Anal. of the outermost MOs gave their energy difference, aiding in predicting stability and other electronic properties. Time dependent d. functional theory was used to analyze the electron excitation and de-excitation dynamics of these mols. and to predict the use of these mols. as effective UV photosensitizers. This work further discusses in detail the natural bond orbital (NBO) studies for intramol. stabilization factors, mol. electrostatic potential (MEP) and hyperpolarizability calculations Further, mol. docking studies were conducted for the compounds with glucan endo-1,6-beta-glucosidase and protein-glutamate methylesterase to predict their utility as potential inhibitors. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Safety of N-(3-Aminopropyl)-imidazole

The Article related to imidazole homo lumo conformation mol docking uv ir spectra, Physical Organic Chemistry: Theoretical Organic Chemical Concepts, Including Quantum and Molecular Mechanical Studies and other aspects.Safety of N-(3-Aminopropyl)-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On October 1, 2021, Bubyrev, Andrey; Adamchik, Maria; Darin, Dmitry; Kantin, Grigory; Krasavin, Mikhail published an article.COA of Formula: C6H11N3 The title of the article was Metal-Free Three-Component Synthesis of 1,2,3-Triazoline-4-Sulfonamides. And the article contained the following:

A new type of diazo compounds, namely, CH-diazomethane sulfonamides (generated in situ from readily available α-acetyl-α-diazomethane sulfonamides MeC(O)C(=N2)S(O)2NRR1 [R = Me; R1 = Ph, Bn, 4-fluorophenyl; RR1 = -(CH2)4-, -(CH2)2O(CH2)2-]) was employed in a 1,3-dipolar cycloaddition reaction with imines (also formed in situ from primary amines R2NH2 (R2 = n-Bu, cyclopentyl, morpholino, etc.) and aldehydes R3CHO (R3 = cyclopropyl, Ph, pyridin-3-yl, etc.)). The reaction gave hitherto undescribed 1,5-disubstituted 1,2,3-triazolin-4-yl sulfonamides I which were obtained in good to excellent yields and complete trans-diastereoselectivity. Oxidative aromatization of 1,2,3-triazolin-4-yl sulfonamides by manganese(IV) oxide gave nearly quant. yields of 1,2,3-triazol-4-yl sulfonamides II of which only two examples have been reported in the literature. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).COA of Formula: C6H11N3

The Article related to triazolyl sulfonamide preparation, triazolinyl sulfonamide preparation diastereoselective oxidative aromatization, acetyl diazomethane sulfonamide amine aldehyde three component dipolar cycloaddition and other aspects.COA of Formula: C6H11N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On April 15, 2020, Suo, Hongbo; Xu, Lili; Xue, Yu; Qiu, Xiang; Huang, He; Hu, Yi published an article.SDS of cas: 5036-48-6 The title of the article was Ionic liquids-modified cellulose coated magnetic nanoparticles for enzyme immobilization: Improvement of catalytic performance. And the article contained the following:

In this work, ionic liquids-modified magnetic CM-cellulose nanoparticles (IL-MCMC) were prepared and used as supports for enzyme immobilization. The specific activity of immobilized lipase PPL-IL-MCMC was 1.43 and 2.81 folds higher than that of free PPL and PPL-MCMC, resp. Water contact angle anal. indicated that the introduction of ionic liquids increased the hydrophobicity of supports, which in tune induced the lid-opening of lipase, allowing its active sites to become more accessible. In addition, the affinity between lipase and substrate immobilized on the prepared supports was enhanced. The same method was also applied to analyze immobilize penicillin G acylase (PGA) to further investigate the general applicability of the method. The results showed that the immobilized PGA exhibited higher stability than many other reported PGAs. The developed composites may be utilized as excellent supports for enzyme immobilization in industrial application. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).SDS of cas: 5036-48-6

The Article related to ionic liquid modified cellulose coated magnetic nanoparticle enzyme immobilization, covalent immobilization, enzymatic performance, hydrophobicity, ionic liquids, magnetic cellulose nanoparticles and other aspects.SDS of cas: 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On August 11, 2020, Li, Yongfei; Chen, Mie; Yao, Bowen; Lu, Xun; Song, Boyang; Vasilatos, Shauna N.; Zhang, Xiang; Ren, Xiaomei; Yao, Chang; Bian, Weihe; Sun, Lizhu published an article.Electric Literature of 5036-48-6 The title of the article was Dual pH/ROS-Responsive Nanoplatform with Deep Tumor Penetration and Self-Amplified Drug Release for Enhancing Tumor Chemotherapeutic Efficacy. And the article contained the following:

Poor deep tumor penetration and incomplete intracellular drug release remain challenges for antitumor nanomedicine application in clin. settings. Herein, a nanomedicine (RLPA-NPs) is developed that can achieve prolonged blood circulation, deep tumor penetration, active-targeting of cancer cells, endosome/lysosome escape, and intracellular selectivity self-amplified drug release for effective drug delivery. The RLPA-NPs are constructed by encapsulation of a pH-sensitive polymer octadecylamine-poly(aspartate-1-(3-aminopropyl) imidazole) (OA-P(Asp-API)) and a ROS-generation agent, β-Lapachone (Lap), in micelles assembled by the tumor-penetration peptide internalizing RGD (iRGD)-modified ROS-responsive paclitaxel (PTX)-prodrug. iRGD could promote RLPA-NPs penetration into deep tumor tissue, and specific targeting to cancer cells. After internalization by cancer cells through receptor-mediated endocytosis, OA-P(Asp-API) can rapidly protonate in the endosome’s acidic environment, resulting in RLPA-NPs escape from the endosome through the “proton sponge effect”. At the same time, the RLPA-NPs micelle disassembles, releasing Lap and PTX-prodrug. Subsequently, the released Lap could generate ROS, consequently amplifying and accelerating PTX release to kill tumor cells. The in vitro and in vivo studies demonstrated that RLPA-NPs can significantly improve the therapeutic effect compared to control groups. Therefore, RLPA-NPs are a promising nanoplatform for overcoming multiple physiol. and pathol. barriers to enhance drug delivery. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Electric Literature of 5036-48-6

The Article related to ph ros responsive nanoparticle micelle antitumor paclitaxel prodrug uptake, deep tumor penetration, lysosome escape, ph/ros-cascade responsive, proton sponge effect, self-amplified drug release and other aspects.Electric Literature of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On March 15, 2020, Huo, Siqi; Yang, Shuang; Wang, Jun; Cheng, Jianwen; Zhang, Qianqian; Hu, Yefa; Ding, Guoping; Zhang, Qiaoxin; Song, Pingan published an article.Name: N-(3-Aminopropyl)-imidazole The title of the article was Liquid phosphorus-containing imidazole derivative as flame-retardant curing agent for epoxy resin with enhanced thermal latency, mechanical, and flame-retardant performances. And the article contained the following:

The development of phosphorus-containing flame retardants combining good compatibility with matrix, low curing temperature, and mech. reinforcing effect has remained a major challenge. Herein, we reported the synthesis of a liquid flame-retardant curing agent (DA) via the nucleophilic substitution between diphenylphosphinic chloride and 1-(3-aminopropyl)-imidazole (AI). DA exhibited good blending and latency towards epoxy resin (EP) at room temperature According to DSC studies, DA could rapidly cure EP at moderate temperature Compared with EP/AI sample, EP/DA samples displayed comparable or higher glass transition temperature (Tg) and enhanced mech. properties due to the introduction of rigid diphenylphosphinyl group and improved crosslinking d. Moreover, DA improved the flame-retardant performances of EP thermoset. For instance, the LOI and UL94 rating of EP/DA-16 sample achieved 37.2% and V-0, resp. In addition, the peak of heat release rate (PHRR), average of heat release rate (AHRR), fire growth rate (FIGRA), and total heat release (THR) for EP/DA-16 sample reduced by 32%, 42%, 28% and 27% in comparison to EP/AI sample, resp. DA was characterized by its good compatibility with EP, moderate curing temperature, fast curing rate, suitable thermal latency, mech. reinforcing and flame-retardant effects, and thus it had a broad application prospect in various industrial fields. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Name: N-(3-Aminopropyl)-imidazole

The Article related to epoxy resin liquid phosphorus imidazole thermal latency flame retardancy, epoxy resin, flame retardancy, liquid phosphorus-containing imidazole, mechanical properties, thermal latency and other aspects.Name: N-(3-Aminopropyl)-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On December 15, 2022, Liu, Lin; Wu, Yan; Song, Ru; Zhang, Yu; Ma, Yafei; Wan, Jun; Zhang, Meili; Cui, Huali; Yang, Hua; Chen, Xiaoli; Wang, Jijiang published an article.Formula: C6H11N3 The title of the article was Morphology engineering and photothermal effect derived from perylene diimide based derivative for boosting photocatalytic hydrogen evolution of ZnIn2S4. And the article contained the following:

The construction of excellent photocatalysts for splitting water into hydrogen is highly desirable to realize carbon neutralization. In this work, an innovative and well-designed S-scheme photocatalyst composed of ultrathin ZnIn2S4 (ZIS) nanosheets uniformly anchored on the surface of organic semiconductor PDIIM is successfully fabricated. Within the heterojunction, perylene diimide with an imidazole group (PDIIM) is strategically applied as a structure template, which plays a crucial role in optimizing the morphol., increasing the active sites of sulfur vacancies, providing the addnl. photothermal effect, and promoting photogenerated charge separation of the catalyst. The photocatalytic H2 generation rate of the ZIS/PDIIM heterojunction with an optimized mass ratio reaches up to 13.04 mmol/g/h, which is 2.64 times and 14.02 times higher than that of pristine ZIS and PDIIM, resp. The outstanding photocatalytic activity is attributed to the synergistic effect of the above advantages. Importantly, the photothermal effect induced by PDIIM belonging to the perylene diimide-based derivative was discovered to accelerate photocatalytic H2 generation for the first time. This work provides valuable insight into the utilization of perylene diimide-based derivatives in the construction of multi-effect enhancement photocatalysts and their application in photothermal-assisted photocatalytic hydrogen evolution. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Formula: C6H11N3

The Article related to indium zinc sulfide perylene diimide hydrogen evolution reaction catalyst, organic semiconductor, perylene diimide, photocatalytic hydrogen evolution, photothermal effect, znin(2)s(4) and other aspects.Formula: C6H11N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On October 1, 2021, Bubyrev, Andrey; Adamchik, Maria; Darin, Dmitry; Kantin, Grigory; Krasavin, Mikhail published an article.COA of Formula: C6H11N3 The title of the article was Metal-Free Three-Component Synthesis of 1,2,3-Triazoline-4-Sulfonamides. And the article contained the following:

A new type of diazo compounds, namely, CH-diazomethane sulfonamides (generated in situ from readily available α-acetyl-α-diazomethane sulfonamides MeC(O)C(=N2)S(O)2NRR1 [R = Me; R1 = Ph, Bn, 4-fluorophenyl; RR1 = -(CH2)4-, -(CH2)2O(CH2)2-]) was employed in a 1,3-dipolar cycloaddition reaction with imines (also formed in situ from primary amines R2NH2 (R2 = n-Bu, cyclopentyl, morpholino, etc.) and aldehydes R3CHO (R3 = cyclopropyl, Ph, pyridin-3-yl, etc.)). The reaction gave hitherto undescribed 1,5-disubstituted 1,2,3-triazolin-4-yl sulfonamides I which were obtained in good to excellent yields and complete trans-diastereoselectivity. Oxidative aromatization of 1,2,3-triazolin-4-yl sulfonamides by manganese(IV) oxide gave nearly quant. yields of 1,2,3-triazol-4-yl sulfonamides II of which only two examples have been reported in the literature. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).COA of Formula: C6H11N3

The Article related to triazolyl sulfonamide preparation, triazolinyl sulfonamide preparation diastereoselective oxidative aromatization, acetyl diazomethane sulfonamide amine aldehyde three component dipolar cycloaddition and other aspects.COA of Formula: C6H11N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On April 15, 2020, Suo, Hongbo; Xu, Lili; Xue, Yu; Qiu, Xiang; Huang, He; Hu, Yi published an article.SDS of cas: 5036-48-6 The title of the article was Ionic liquids-modified cellulose coated magnetic nanoparticles for enzyme immobilization: Improvement of catalytic performance. And the article contained the following:

In this work, ionic liquids-modified magnetic CM-cellulose nanoparticles (IL-MCMC) were prepared and used as supports for enzyme immobilization. The specific activity of immobilized lipase PPL-IL-MCMC was 1.43 and 2.81 folds higher than that of free PPL and PPL-MCMC, resp. Water contact angle anal. indicated that the introduction of ionic liquids increased the hydrophobicity of supports, which in tune induced the lid-opening of lipase, allowing its active sites to become more accessible. In addition, the affinity between lipase and substrate immobilized on the prepared supports was enhanced. The same method was also applied to analyze immobilize penicillin G acylase (PGA) to further investigate the general applicability of the method. The results showed that the immobilized PGA exhibited higher stability than many other reported PGAs. The developed composites may be utilized as excellent supports for enzyme immobilization in industrial application. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).SDS of cas: 5036-48-6

The Article related to ionic liquid modified cellulose coated magnetic nanoparticle enzyme immobilization, covalent immobilization, enzymatic performance, hydrophobicity, ionic liquids, magnetic cellulose nanoparticles and other aspects.SDS of cas: 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On August 11, 2020, Li, Yongfei; Chen, Mie; Yao, Bowen; Lu, Xun; Song, Boyang; Vasilatos, Shauna N.; Zhang, Xiang; Ren, Xiaomei; Yao, Chang; Bian, Weihe; Sun, Lizhu published an article.Electric Literature of 5036-48-6 The title of the article was Dual pH/ROS-Responsive Nanoplatform with Deep Tumor Penetration and Self-Amplified Drug Release for Enhancing Tumor Chemotherapeutic Efficacy. And the article contained the following:

Poor deep tumor penetration and incomplete intracellular drug release remain challenges for antitumor nanomedicine application in clin. settings. Herein, a nanomedicine (RLPA-NPs) is developed that can achieve prolonged blood circulation, deep tumor penetration, active-targeting of cancer cells, endosome/lysosome escape, and intracellular selectivity self-amplified drug release for effective drug delivery. The RLPA-NPs are constructed by encapsulation of a pH-sensitive polymer octadecylamine-poly(aspartate-1-(3-aminopropyl) imidazole) (OA-P(Asp-API)) and a ROS-generation agent, β-Lapachone (Lap), in micelles assembled by the tumor-penetration peptide internalizing RGD (iRGD)-modified ROS-responsive paclitaxel (PTX)-prodrug. iRGD could promote RLPA-NPs penetration into deep tumor tissue, and specific targeting to cancer cells. After internalization by cancer cells through receptor-mediated endocytosis, OA-P(Asp-API) can rapidly protonate in the endosome’s acidic environment, resulting in RLPA-NPs escape from the endosome through the “proton sponge effect”. At the same time, the RLPA-NPs micelle disassembles, releasing Lap and PTX-prodrug. Subsequently, the released Lap could generate ROS, consequently amplifying and accelerating PTX release to kill tumor cells. The in vitro and in vivo studies demonstrated that RLPA-NPs can significantly improve the therapeutic effect compared to control groups. Therefore, RLPA-NPs are a promising nanoplatform for overcoming multiple physiol. and pathol. barriers to enhance drug delivery. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Electric Literature of 5036-48-6

The Article related to ph ros responsive nanoparticle micelle antitumor paclitaxel prodrug uptake, deep tumor penetration, lysosome escape, ph/ros-cascade responsive, proton sponge effect, self-amplified drug release and other aspects.Electric Literature of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem