Category: imidazoles-derivatives

Cante-Mota, Ivon published the artcileBenzimidazole-derived Calix[4]arenes with Polymerizable Styrene Groups and Their Cu(II) Complexes, Quality Control of 4760-35-4, the publication is Inorganica Chimica Acta (2013), 11-18, database is CAplus.

P-tert-Butylcalix[4]arene [C4(OH)₄] was substituted with one to four benzimidazole groups at the phenolic positions affording the compounds C4(OH)₃(OBzIm)-C4(OBzIm)₄. The solid-state structures confirmed the cone conformation of all derivatives A tetrasubstituted calix[4]arene with two benzimidazole groups and two 4-methylenestyryl in distal positions C4(OStyr)₂(OBzIm)₂, which are amenable for polymerization reactions, was also obtained. The monobenzimidazole compound C4(OH)₃(OBzIm) reverts to a partial-cone conformation on binding CuCl₂, giving rise to the dimeric complex [C4(OH)₂(OBzIm)₂]₂[CuCl(μ-Cl)]₂ in the solid state, featuring N and O-coordination from the benzimidazole-N and ethereal-O atoms towards the Cu²⁺ ions placed outside the calixarene cavity. In contrast, the tetrasubstituted C4(OStyr)₂(OBzIm)₂ gives rise to the crystallog.-characterized monomeric complex [C4(OStyr)₂(OBzIm)₂CuCl₂], with the cupric ion located directly above the macrocyclic cavity. This complex has 4-methylenestyryl groups at two distal phenolic positions, ideally poised for further modifications, including polymerization of the copper-containing monomer.

Inorganica Chimica Acta published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Quality Control of 4760-35-4.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Kurosu, Michio published the artcileSmall-molecule microarrays: Development of novel linkers and an efficient detection method for bound proteins, Product Details of C16H21N3O3S, the publication is Bioorganic & Medicinal Chemistry Letters (2006), 16(13), 3392-3395, database is CAplus and MEDLINE.

Novel isocyanate and diazoketone linkers possessing polyoxypropylenediamine as a spacer for small-mol. microarray are developed. White light interferometry is introduced to detect bound proteins on the glass slides without using chem. modified proteins.

Bioorganic & Medicinal Chemistry Letters published new progress about 901770-40-9. 901770-40-9 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Amide, name is N-(4-Hydroxyphenyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C16H21N3O3S, Product Details of C16H21N3O3S.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Howard, Philip H. published the artcileIdentifying New Persistent and Bioaccumulative Organics Among Chemicals in Commerce II: Pharmaceuticals, HPLC of Formula: 161796-78-7, the publication is Environmental Science & Technology (2011), 45(16), 6938-6946, database is CAplus and MEDLINE.

The goal was to identify com. pharmaceuticals that might be persistent and bioaccumulative (P&B) and that were not being considered in current wastewater and aquatic environmental measurement programs. We developed a database of 3193 pharmaceuticals from 2 US Food and Drug Administration (FDA) databases and some lists of top ranked or selling drugs. Of the 3193 pharmaceuticals, 275 pharmaceuticals have been found in the environment and 399 pharmaceuticals were, based on production volumes, designated as high production volume (HPV) pharmaceuticals. All pharmaceuticals that had reported chem. structures were evaluated for potential bioaccumulation (B) or persistence (P) using quant. structure property relationships (QSPR) or scientific judgment. Of the 275 drugs detected in the environment, 92 were rated as potentially bioaccumulative, 121 were rated as potentially persistent, and 99 were HPV pharmaceuticals. After removing the 275 pharmaceuticals previously detected in the environment, 58 HPV compounds were identified that were both P&B and 48 were identified as P only. Of the non-HPV compounds, 364 pharmaceuticals were identified that were P&B. This study has yielded some interesting and probable P&B pharmaceuticals that should be considered for further study.

Environmental Science & Technology published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C17H18N3NaO3S, HPLC of Formula: 161796-78-7.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Sarkar, Sujoy published the artcileIonic liquid-assisted synthesis of tri-functional ruthenium oxide nanoplatelets for electrochemical energy applications, SDS of cas: 79917-90-1, the publication is Journal of Materials Science (2022), 57(15), 7680-7693, database is CAplus.

Nanostructured crystalline metal oxides are in great demand in industrial processes due to their unique physicochem. properties and ionic liquids (ILs) are promising solvent for synthesizing such materials. Herein, we report an IL-assisted, facile, and environmental benign approach to synthesize rutile phase of ruthenium oxide (RuO₂) nanoplatelets (NPLs) structure with a size distribution of a few tens of nm. The key to this synthesis methodol. is the use of imidazolium-based ILs as solvents and binder in the ionothermal process. The obtained RuO₂ phase is thoroughly characterized by spectroscopic and microscopic techniques. Further, the material is used as electrocatalyst toward electrochem. energy storage and conversion in an alk. solution The platelet morphol. of RuO₂ exhibits excellent supercapacitor performance and its capacitance value is âˆ?200 F g^-1 in 1 M KOH solution Besides, the as-synthesized RuO₂ NPLs shows superior water oxidation and chlorine evolution processes at a minimal overpotential, i.e., 1.47 V in 1 M KOH and 1.5 V in 3 M KCl (pH 3) electrolyte, resp., exhibiting its tri-functional electrochem. behavior toward production of renewable energies. The present study demonstrates that single-step production of the NPL morphol. of RuO₂ has potential implications in the field of electrolysis and supercapacitors.

Journal of Materials Science published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, SDS of cas: 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Wei, Yi-Ming published the artcileIron-catalyzed stereospecific arylation of enol tosylates using Grignard reagents, Related Products of imidazoles-derivatives, the publication is Chemical Communications (Cambridge, United Kingdom) (2020), 56(7), 1101-1104, database is CAplus and MEDLINE.

The stereospecific Fe-catalyzed arylation of enol tosylates with Grignard reagents was reported for the synthesis of Z- and E- tri/tetrasubstituted acrylates (Ar)(R)C=C(CO₂R¹)(R²) [R = Me, i-Pr, Ph, etc.; R¹ = Me, Et; R² = H, Me, Ph; Ar = Ph, 2-CNC₆H₄, 2-thienyl, etc.]. Various tri- or tetrasubstituted Z or E-enol tosylates of β-keto esters were arylated using common and Knochel-type Grignard reagents with complete stereofidelity. The precursors for Z/E-zimelidine, tamoxifen and other bioactive compounds were facilely prepared without precious and toxic transition metals.

Chemical Communications (Cambridge, United Kingdom) published new progress about 258278-25-0. 258278-25-0 belongs to imidazoles-derivatives, auxiliary class Achiral NHCs Ligands, name is 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride, and the molecular formula is C39H35N5O8, Related Products of imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Ding, Haoshu published the artcilePyrolytic characteristics of Fushun oil shale and its by-products, Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, the publication is Journal of Thermal Analysis and Calorimetry (2022), 147(8), 5255-5267, database is CAplus.

FTIR, TG-DTG, TG-FTIR, and Py-GC-MS were employed to investigate the similarities and differences in the pyrolytic characteristics of Fushun oil shale and its byproducts, i.e., semi-coke and residual. The semi-coke was obtained by slowly pyrolyzing the oil shale to 450°C. The residual was a solid residue prepared by completely extracting the semi-coke with a 1-butyl-3-methylimidazolium chloride and N-Me pyrrolidon mixture The pyrolysis of three samples is related to the cleavages of weak bonds (200-400°C), decomposition of major organic structures (400-600°C), and the cleavages of 3-4 kinds of chem. bonds. Gaussian fitting methods was used to fit the DTG curves to evaluate the contributions of various covalent bonds to the pyrolysis. The flash pyrolysis products and typical gaseous products were identified, showing the most outstanding performances of the aliphatic compounds The differences in the pyrolytic characteristics of three samples are mainly attributed to the diverse forms of thermal bitumen. The attendance of thermal bitumen in the semi-coke, especially its light components generated from oil shale pyrolysis, prompts the more active mass loss behaviors at relatively low temperatures, while the absence of thermal bitumen results in a fairly low mass loss of the residual.

Journal of Thermal Analysis and Calorimetry published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Kosmulski, Marek published the artcileZeta potential in dispersions of titania nanoparticles in moderately polar solvents stabilized with anionic surfactants, Application of 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, the publication is Journal of Molecular Liquids (2022), 118972, database is CAplus.

Electrophoretic mobility of titania nanoparticles in ethane-1,2-diol and in propane-1,2-diol in the presence of SDS and sodium octadecylsulfate was measured. Several dispersions were acidified with HCl or alkalized with NaOH. Addition of acid resulted in pos. and addition of base resulted in neg. zeta potential. Anionic surfactants have moderate effect on the zeta potential. They enhanced neg. zeta potential, but their effect became significant at surfactant concentrations as high as 1 g/L. Sodium octadecylsulfate was more efficient than SDS in shifting the zeta potential to more neg. values.

Journal of Molecular Liquids published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Application of 3-Butyl-1-methyl-1H-imidazol-3-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Ariki, Zachary T. published the artcilePreparation of Quaternary Centers via Nickel-Catalyzed Suzuki-Miyaura Cross-Coupling of Tertiary Sulfones, Category: imidazoles-derivatives, the publication is Journal of the American Chemical Society (2018), 140(1), 78-81, database is CAplus and MEDLINE.

We describe the development of a nickel-catalyzed Suzuki-Miyaura cross-coupling of tertiary benzylic and allylic sulfones with arylboroxines. A variety of tertiary sulfones, which can easily be prepared via a deprotonation-alkylation route, were reacted to afford sym. and unsym. quaternary products in good yields. We highlight the use of either BrettPhos or Doyle’s phosphines as effective ligands for these challenging desulfonative coupling reactions. The utility of this methodol. was demonstrated in the concise synthesis of a vitamin D receptor modulator analog.

Journal of the American Chemical Society published new progress about 258278-25-0. 258278-25-0 belongs to imidazoles-derivatives, auxiliary class Achiral NHCs Ligands, name is 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride, and the molecular formula is C27H39ClN2, Category: imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Basappa, B. H. Doreswamy published the artcileReduction of aldehydes and oximes to their corresponding alcohols and amines by catalytic hydrogenation method, HPLC of Formula: 79047-41-9, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2005), 44B(1), 148-151, database is CAplus.

The reduction of aldehydes such as 2-butyl-5-chloro-3H-imidazole-5-carboxaldehyde and veratraldehyde, which are pharmaceutical key intermediates, were reduced to alcs. by a catalytic hydrogenation method in the presence of Mg and also oximes are reduced to primary amines successively by the Mg/ammonium formate system, is a large scale feasible and cheaper method. The crystal structure of the product, 2-butyl-5-chloro-3H-imidazole-4-ylmethanol, is reported.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 79047-41-9. 79047-41-9 belongs to imidazoles-derivatives, auxiliary class Imidazole,Chloride,Alcohol, name is (2-Butyl-4-chloro-1H-imidazol-5-yl)methanol, and the molecular formula is C8H13ClN2O, HPLC of Formula: 79047-41-9.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Goswami, Shyamaprosad published the artcileA FRET-based rhodamine-benzimidazole conjugate as a Cu²⁺-selective colorimetric and ratiometric fluorescence probe that functions as a cytoplasm marker, Safety of 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, the publication is RSC Advances (2014), 4(12), 6300-6305, database is CAplus.

On the basis of fluorescence resonance energy transfer (FRET) from benzimidazole to a rhodamine moiety, a rhodamine-benzimidazole conjugate (RBC) ratiometric fluorescent probe has been designed and synthesized. The RBC selectively binds to Cu²⁺, showing visually observable changes in absorption and emission behavior, and demonstrates an effective intracellular Cu²⁺ imaging ability, allowing it to function as a cytoplasm marker.

RSC Advances published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Safety of 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem