Category: imidazoles-derivatives

Li, Dandan published the artcileIntensifying the moderate electric field-induced modification of maize starch by 1-butyl-3-methylimidazolium chloride, Synthetic Route of 79917-90-1, the publication is Carbohydrate Polymers (2022), 119654, database is CAplus and MEDLINE.

This study aimed to improve the effect of moderate elec. field (MEF) treatment on the structural and physicochem. properties of maize starch by adding 1-butyl-3-methylimidazolium chloride ([bmim]Cl). Starch (20%, w/v) was mixed with [bmim]Cl solution (0, 30%, 50%, and 70%, weight/weight), and then electro-treated (5 V/cm, 50 Hz) at 60 °C for 10 min. As the [bmim]Cl concentration increased, the electro-induced disintegration of starch granules was enhanced due to the intensified Joule heat and decreased pH of reaction bulk. After electro-treated in 70% weight/weight [bmim]Cl, a transparent solution of starch was observed and the recovered starch tended to dissolve rather than swell in water. Compared with water-bath heating, MEF caused more destruction in the granular and crystal structure, increased the particle size, decreased the pasting viscosity, and reduced the gelatinization enthalpy and thermostability of starch. The obtained results could provide guidance for the application of electro-based techniques in starch modification.

Carbohydrate Polymers published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Synthetic Route of 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Gong, Yanmei published the artcileHigh performance benzoimidazolyl-based aminophenolate zinc complexes for isoselective polymerization of rac-lactide, Formula: C9H9ClN2, the publication is Chemical Communications (Cambridge, United Kingdom) (2019), 55(68), 10112-10115, database is CAplus and MEDLINE.

Zinc complexes supported by achiral benzoimidazolyl-based aminophenolate ligands exhibit high catalytic activities and excellent isoselectivities toward the ring-opening polymerization of rac-lactide under mild conditions.

Chemical Communications (Cambridge, United Kingdom) published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Formula: C9H9ClN2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Wu, Wenna published the artcilePolyelectrolyte aerogels with regeneration capacity for efficient removal of particulate matters, Formula: C8H15ClN2, the publication is Journal of Colloid and Interface Science (2022), 446-456, database is CAplus and MEDLINE.

With the rapid development of economy and global industrialization, the problem of air pollution has become a worldwide topic. The efficient filtration of airborne particulate matters (PMs) is critical for human health and environmental sustainability. Herein, self-supporting bio-based polyelectrolyte aerogels were prepared and acted as the advanced filters for efficient removal of PMs. The natural choline cation (Ch⁺) or the organic cation, 1-butyl-3-methylimidazolium (Bmim⁺), are introduced into alginate (Alg^–) to form the polyelectrolytes of ChAlg or BmimAlg due to the electrostatic interaction. By the directional freeze-drying in liquid N₂, hierarchically porous aerogels with mech. robustness, flexibility and thermo-stability were prepared This specific structure may permit the polluted air to pass adequately through the aerogel channels, which are conducive to intercept various PMs with different diameters As an example, the removal efficiency of ChAlg aerogels for PM₁₀, PM_2.5 and PM_0.3 are resp. up to (99.24 ± 0.03)%, (99.22 ± 0.02)%, and (93.41 ± 0.22)% within 15 h durability test. One outstanding character lies in ensuring high removal efficiency, while achieving a good balance with the low pressure drop (10 Pa), which is driven by synergistic effect of passive trapping and electrostatic capture. Moreover, the polyelectrolyte aerogels exhibit excellent antimicrobial activity and regenerated capacity. These properties endow the aerogels of polyelectrolyte ChAlg or BmimAlg with remarkable potential as new advanced filters for masks and other personal protective equipment.

Journal of Colloid and Interface Science published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C24H29N5O3, Formula: C8H15ClN2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Han, Bo published the artcileChromium- and Cobalt-Catalyzed, Regiocontrolled Hydrogenation of Polycyclic Aromatic Hydrocarbons: A Combined Experimental and Theoretical Study, Computed Properties of 258278-25-0, the publication is Journal of the American Chemical Society (2019), 141(22), 9018-9026, database is CAplus and MEDLINE.

Polycyclic aromatic hydrocarbons are difficult substrates for hydrogenation because of the thermodn. stability caused by aromaticity. We report here the first chromium- and cobalt-catalyzed, regiocontrolled hydrogenation of polycyclic aromatic hydrocarbons at ambient temperature These reactions were promoted by low-cost chromium or cobalt salts combined with diimino/carbene ligand and methylmagnesium bromide and are characterized by high regioselectivity and expanded substrate scope that includes tetracene, tetraphene, pentacene, and perylene, which have rarely been reduced. The approach provides a cost-effective catalytic protocol for hydrogenation, is scalable, and can be utilized in the synthesis of tetrabromo- and carboxyl-substituted motifs through functionalization of the hydrogenation product. The systematic theor. mechanistic modelings suggest that low-valent Cr and Co monohydride species, most likely from zerovalent transition metals, are capable of mediating these hydrogenations of fused PAHs.

Journal of the American Chemical Society published new progress about 258278-25-0. 258278-25-0 belongs to imidazoles-derivatives, auxiliary class Achiral NHCs Ligands, name is 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride, and the molecular formula is C27H39ClN2, Computed Properties of 258278-25-0.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Yu, Hua-Zhong published the artcileReading Disc-Based Bioassays with Standard Computer Drives, Recommanded Product: N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, the publication is Accounts of Chemical Research (2013), 46(2), 258-268, database is CAplus and MEDLINE.

Traditional methods of disease diagnosis are both time-consuming and labor-intensive, and many tests require expensive instrumentation and trained professionals, which restricts their use to biomedical laboratories Because patients can wait several days (even weeks) for the results, the consequences of delayed treatment could be disastrous. Therefore, affordable and simple point-of-care (POC) biosensor devices could fill a diagnostic niche in the clinic or even at home, as personal glucose meters do for diabetics. These devices would allow patients to check their own health conditions and enable physicians to make prompt treatment decisions, which could improve the chances for rapid recovery and cure. Compact disks (CDs) provide inexpensive substrate materials for the preparation of microarray biochips, and conventional computer drives/disk players can be adapted as precise optical reading devices for signal processing. Researchers can employ the polycarbonate (PC) base of a CD as an alternative substrate to glass slides or silicon wafers for the preparation of microanal. devices. Using the characteristic optical phenomena occurring on the metal layer of a CD, researchers can develop biosensors based on advanced spectroscopic readout (interferometry or surface plasmon resonance). If researchers integrate microfluidic functions with CD mechanics, they can control fluid transfer through the spinning motion of the disk, leading to “lab-on-a-CD” devices. Over the last decade, the authors’ laboratory has focused on the construction of POC biosensor devices from off-the-shelf CDs or DVDs and standard computer drives. Besides the initial studies of the suitability of CDs for surface and materials chem. research (fabrication of self-assembled monolayers and oxide nanostructures), an ordinary optical drive, without modification of either the hardware or the software driver, can function as the signal transducing element for reading disk-based bioassays quant. In this Account, the authors first provide a brief introduction to CD-related materials chem. and microfluidics research. Then the authors describe the mild chem. developed in the authors’ laboratory for the preparation of computer-readable biomol. screening assays: photochem. activation of the polycarbonate (PC) disk surface and immobilization and delivery of probe and target biomols. The authors thoroughly discuss the anal. of the mol. recognition events: researchers can “read” these devices quant. with an unmodified optical drive of any personal computer. Finally, and critically, the authors illustrate the authors’ digitized mol. diagnosis approach with three trial systems: DNA hybridization, antibody-antigen binding, and ultrasensitive lead detection with a DNAzyme assay. These examples demonstrate the broad potential of this new anal./diagnostic tool for medical screening, on-site food/water safety testing, and remote environmental monitoring.

Accounts of Chemical Research published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C7H16ClNO2, Recommanded Product: N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Lin, Shu-yu published the artcileStudy on compatible stability of esomeprazole sodium for injection with six kinds of common solvents, Computed Properties of 161796-78-7, the publication is Yiyao Daobao (2012), 31(9), 1210-1213, database is CAplus.

The appropriate HPLC detection for studying the stability of esomeprazole (Eso) sodium for injection with six kinds of common solvents was investigated, and thus provided an evidence for using reasonable compound preparation in clin. use. The Eso sodium for injection was compatible with 100 mL six kinds of common solvents resp., and the pH value was detected. The content of Eso sodium in the compatible solution was analyzed by HPLC. The color and clarity were observed at regular time. Eso showed a good linear relationship within the range of 0.05-1.60 mg·mL^-1 (R²=0.9999). There were no significant changes on pH value, color, clarity and content within 24 h after being mixed with 0.9% sodium chloride injection and xylitol one. No distinct changes appeared 12 h, 8 h and 6 h after being mixed with 10% GS, 5% GS, 5% GNS injection, and the Eso solutions of which were relatively stable. While, the situation was different for Eso mixed with fructose injection. Eso was incompatible with fructose injection and showed better compatibility with 0.9% NS or 5% xylitol injection. The drip of admixture should be finished within 12 h, 8 h and 6 h when mixing with 10% GS, 5% GS, 5% GNS, resp.

Yiyao Daobao published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C17H18N3NaO3S, Computed Properties of 161796-78-7.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Tran, Van T. published the artcileNi(COD)(DQ): An Air-Stable 18-Electron Nickel(0)-Olefin Precatalyst, Formula: C27H39ClN2, the publication is Angewandte Chemie, International Edition (2020), 59(19), 7409-7413, database is CAplus and MEDLINE.

We report that Ni(COD)(DQ) (COD = 1,5-cyclooctadiene, DQ = duroquinone), an air-stable 18-electron complex originally described by Schrauzer in 1962, is a competent precatalyst for a variety of nickel-catalyzed synthetic methods from the literature. Due to its apparent stability, use of Ni(COD)(DQ) as a precatalyst allows reactions to be conveniently performed without use of an inert-atm. glovebox, as demonstrated across several case studies.

Angewandte Chemie, International Edition published new progress about 258278-25-0. 258278-25-0 belongs to imidazoles-derivatives, auxiliary class Achiral NHCs Ligands, name is 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride, and the molecular formula is C14H10O4, Formula: C27H39ClN2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Zhou, Yan-Ling published the artcileBis[(1-methyl-1H-benzimidazol-2-yl)methanol-κ²N³,O]bis(thiocyanato-κN)cobalt(II) methanol solvate, SDS of cas: 7467-35-8, the publication is Acta Crystallographica, Section E: Structure Reports Online (2010), 66(2), m189, Sm189/1-Sm189/9, database is CAplus and MEDLINE.

In bis[(1-methyl-1H-benzimidazol-2-yl)methanol-κ²N³,O]bis(thiocyanato-κN)cobalt monomethanolate, [Co(NCS)₂(C₉H₁₀N₂O)₂]·MeOH, the Co(II) ion is surrounded by 2 (1-Me-1H-benzimidazol-2-yl)methanol bidentate ligands and 2 thiocyanate ligands, and exhibits a distorted octahedral coordination by 4 N atoms and 2 O atoms. The structure is consolidated by H bonds between the organic ligand, thiocyanate anion and the uncoordinated MeOH mol., leading to a chain along [100]. Crystallog. data are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 7467-35-8. 7467-35-8 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Alcohol, name is (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, and the molecular formula is C12H17NS2, SDS of cas: 7467-35-8.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Zhou, Yan-Ling published the artcileDiazidobis[(1-methyl-1H-benzimidazol-2-yl)methanol-κ²N³,O]manganese(II), Recommanded Product: (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, the publication is Acta Crystallographica, Section E: Structure Reports Online (2010), 66(2), m188, Sm188/1, database is CAplus and MEDLINE.

Diazidobis[(1-methyl-1H-benzimidazol-2-yl)methanol-κ²N³,O]manganese, [Mn(N₃)₂(C₉H₁₀N₂O)₂], possesses crystallog. imposed 2-fold symmetry. The Mn^II atom is coordinated by 4 N atoms and 2 O atoms in a distorted octahedral geometry. The crystal packing is stabilized by strong intermol. O-H···N H bonds. Crystallog. data are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 7467-35-8. 7467-35-8 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Alcohol, name is (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, and the molecular formula is C12H17NS2, Recommanded Product: (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Wei, Kaijie published the artcileIron-Catalyzed 1,4-Phenyl Migration/Ring Expansion of α-Azido N-Phenyl Amides, Name: 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride, the publication is Organic Letters (2021), 23(21), 8650-8654, database is CAplus and MEDLINE.

A novel iron-catalyzed skeleton rearrangement of alkyl azides was reported. Upon treatment with FeCl₂ and N-heterocyclic carbene S_IPr·HCl in the presence of H₂O and Et₃N, 2-azido-N,N-diphenylamides underwent 1,4-Ph migration and ring expansion to give azepin-2-ones in good yield. The reaction proceeds via intramol. nitrene cycloaddition followed by C-N cleavage, water addition, and electrocyclic ring opening.

Organic Letters published new progress about 258278-25-0. 258278-25-0 belongs to imidazoles-derivatives, auxiliary class Achiral NHCs Ligands, name is 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride, and the molecular formula is C18H10F3NO3S2, Name: 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem