Category: imidazoles-derivatives

Chen, Yong-kang published the artcileStudy of methodology validation of detection sodium content in esomeprazole sodium, Related Products of imidazoles-derivatives, the publication is Huaxue Gongchengshi (2016), 30(4), 67-70, database is CAplus.

In this paper, the at. absorption spectrometry (AAS) method for the determination of sodium in esomeprazole sodium was established. Using the standard curve method, the detection wavelength was 589.0 nm. Exptl. results show that at 589.0 nm the blank solution has no interference with the determination of sodium, linear study shows that the concentration of sodium within 0.5∼4.0 mg·L^-1 range, the absorbance A has a good linear relationship with the concentration of C, and R² is greater than 0.999. By method validation: accuracy, solution stability, repeatability and accuracy are good, at the same time this method has good durability and can be used as the determination method of sodium content in esomeprazole sodium.

Huaxue Gongchengshi published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C17H18N3NaO3S, Related Products of imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Ouyang, Xinhua published the artcileEnhanced efficiency in nondoped, blue organic light-emitting diodes utilizing simultaneously local exciton and two charge-transfer exciton from benzimidazole-based donor-acceptor molecules, COA of Formula: C19H14N2, the publication is Dyes and Pigments (2014), 39-49, database is CAplus.

The simultaneous utilization of all charge-transfer excitons and local excitons is the pathway to obtain the high efficiency fluorescent organic light-emitting diodes (FOLEDs). Here, a twisted intramol. charge transfer state (TICT-state), a planar intramol. charge transfer state (ICT-state), and a locally excited state (LE-state) are demonstrated to enhance the occurrence of singlet excitons in the fluorescent emitters, which are based on benzimidazole and triphenylamine donor-acceptor derivatives The synthesis, photophysics and electroluminescent (EL) performance are studied systematically. The fluorescence emitters (TPABBBI and TPABBI) with the special TICT and ICT characteristics realize the electron-hole (e-h) recombination via intramol. conversion from charge-transfer excitons to radiative singlet exciton. The devices based on them show high efficiency (5.1 cd/A, 5.77 lm/W, 5.66% of EQE_m for TPABBBI and 3.56 cd/A, 3.11 lm/W, 4.23% for TPABBI), low efficiency roll-off at high luminance and stable blue emission.

Dyes and Pigments published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, COA of Formula: C19H14N2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Shi, Xing-Xing published the artcileFerromagnetic coupling in copper benzimidazole chloride: structural, mass spectrometry, magnetism, and DFT studies, Category: imidazoles-derivatives, the publication is Dalton Transactions (2017), 46(47), 16663-16670, database is CAplus and MEDLINE.

Herein, quasi-square planar Cu^II(Hmbm)Cl₂ (CBC, Hmbm = (1-methyl-1H-benzo[d]imidazol-2-yl)methanol) was arranged in a pseudo orthogonal way to form Cl-bridged chains, and further π···π interactions resulted in distorted hexagonal layers. DFT calculations reveal a bond strength order of Cu-Cl > Cu-O/N ≫ Cu···Cl. ESI-MS data reveal several small fragments from CBC, but oligomeric [Cu^II₂], [Cu^II₃], and [Cu^II₄] for non-zero in-source energies; MS data indicates the occurrence of several chem. processes, viz. splitting of the ligand, oligomerization, and redox reaction of alc. to aldehyde and Cu^II to Cu^I. Gibbs free energies for the fragments were estimated using DFT. The magnetic susceptibility was modeled with the ferromagnetic coupling J(Cu-Cl2a···Cu) = +0.99(30) cm^-1 and J'(π···π) = +0.35(16) cm^-1 and g = 2.38(2). HF-EPR determined the anisotropic g-values, g_x = 2.24, g_y = 2.16, and g_z = 2.09, and a hyperfine constant of A_z = 450 G. DFT calculations from crystal structure data reveal a J(Cu-Cl2a···Cu) of +3.6 at 296 K and +4.1 cm^-1 at 90 K that dominates the magnetic properties, whereas J'(π···π) = 0.04 cm^-1 is negligibly small.

Dalton Transactions published new progress about 7467-35-8. 7467-35-8 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Alcohol, name is (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, and the molecular formula is C8H17Br, Category: imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

An, Lianying published the artcileSyntheses of a green organic phosphorescence materials and studies on their photoluminescent properties, Recommanded Product: 1,2-Diphenyl-1H-benzo[d]imidazole, the publication is Advanced Materials Research (Durnten-Zurich, Switzerland) (2012), 455-456(Pt. 2), 880-883, database is CAplus.

By using the N-phenyl-o-nitroaniline and benzoyl chloride as initial raw materials, a green light-emitting material (pbi)₂Ir(acac)₂ (pbiH = 1,2-diphenylbenzimidazole) was produced via a new designed synthesis plan. The structure of the complex was characterized by IR, MS, and DTA. The optical Luminescence Properties of the complex was studied by fluorescence spectrometry anal. The m.p. of the product is 343° which showed that it had thermal stability. The fluorescence spectrometry anal. exptl. results show that the excitation and emission peaks of the organic Ir(III) complex were, resp., 470.6 nm and 526.21 nm which showed that it belongs to green high-brightness light-emitting materials. The oxidation of the intermediate products exposed in air which could cause the quality of product instability was avoided in the new, improved synthesis plan.

Advanced Materials Research (Durnten-Zurich, Switzerland) published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Recommanded Product: 1,2-Diphenyl-1H-benzo[d]imidazole.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Hu, Zhiyuan published the artcileI₂-Mediated Intramolecular C-H Amidation for the Synthesis of N-Substituted Benzimidazoles, Application In Synthesis of 2622-67-5, the publication is Journal of Organic Chemistry (2017), 82(6), 3152-3158, database is CAplus and MEDLINE.

A practical intramol. C-H amidation methodol. has been developed using mol. iodine under basic conditions. The required imine substrates were readily obtained by condensation of simple o-phenylenediamine derivatives and aldehydes. The transition-metal-free cyclization reaction described here works well with crude imines and allows for the sequential synthesis of N-protected 2-substituted benzimidazoles without purification of the less stable condensation intermediates. This operationally simple synthetic approach is broadly applicable to a variety of aromatic, aliphatic, and cinnamic aldehydes to produce diverse 1,2-disubstituted benzimidazole derivatives in an efficient and scalable fashion.

Journal of Organic Chemistry published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Application In Synthesis of 2622-67-5.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Sun, Xinqi published the artcileDetermination of residual solvents in antazoline hydrochloride, Formula: C17H20ClN3, the publication is Henan Daxue Xuebao, Ziran Kexueban (2009), 39(1), 25-28, database is CAplus.

Capillary gas chromatog. was used to determine residual solventsin antazoline hydrochloride. The linear equation of ethanol is Y = 0.04627 +0.65369X, r = 0.99816 (n = 8), and the range of linearity is 50.35-718.9 g/L and average recovery rate is 98.32% with RSD of 6.79%. The linear equation of toluene is Y = 0.01928 +1.64319X, r = 0.99372 (n = 8), and the range of linearity is 11.6-162.4 g/L and average recovery rate is 98.17% with RSD of 1.5%. The linear equation of DMF is Y = 0.02531 +0.35654X, r = 0.99344 (n = 8), and the range of linearity is 9.8-137.2 g/L and average recovery rate is 98.99% with RSD of 2.34%. Capillary gas chromatog. can be used for determination of antazoline hydrochloride products.

Henan Daxue Xuebao, Ziran Kexueban published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C14H12N2S, Formula: C17H20ClN3.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Jiang, Biao published the artcileCatalytic asymmetric oxidation of heteroaromatic sulfides with tert-butyl hydroperoxide catalyzed by a titanium complex with a new chiral 1,2-diphenylethane-1,2-diol ligand, Formula: C17H18N3NaO3S, the publication is European Journal of Organic Chemistry (2009), 987-991, database is CAplus.

Heteroaromatic sulfoxides, especially 1H-benzimidazolyl pyridinylmethyl sulfoxides, usually used as the blockbuster gastric proton pump inhibitors (PPIs), have been prepared highly enantioselectivity by catalytic asym. oxidation of sulfides attached to nitrogen-containing heterocycles with tert-Bu hydroperoxide in the presence of a chiral titanium complex, formed in situ from Ti(iPrO)₄, chiral 1,2-diphenylethane-1,2-diol and water. The chiral sulfoxides were obtained in high yield (97%) with excellent enantiomeric excess (up to 98%).

European Journal of Organic Chemistry published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C17H18N3NaO3S, Formula: C17H18N3NaO3S.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Cao, Mengyan published the artcileRapid and Large-Scale Preparation of Stable and Efficient White Light Emissive Perovskite Microcrystals Using Ionic Liquids, Related Products of imidazoles-derivatives, the publication is Journal of Physical Chemistry Letters (2022), 13(26), 6048-6056, database is CAplus and MEDLINE.

In this work, we report large-scale preparation of stable Sb³⁺ and Bi³⁺ codoped Cs₂ZrCl₆ microcrystals for highly efficient white light emission using ionic liquids, demonstrating a broad dual-band white emission covering 400-800 nm. The dual emissions originate from the associated self-trapped excitons of the [SbCl₆]^3- and [BiCl₆]^3- octahedra. Moreover, the ratio of the dual-emission peaks can be effectively regulated by tuning the excitation wavelength. Meanwh000.0.0.0.0.ile, to improve the optical properties and stability, ionic liquids are employed to assist the synthesis process of perovskite materials. The white light emission of one of the samples demonstrates CIE coordinates right in the center of the white light region (0.334, 0.331) and an excellent color rendering index (~90.3), accompanied by a 66.1% quantum efficiency. Moreover, our method allows the facile synthesis of large batches of microcrystalline powders. Our findings demonstrate the potential of white phosphors as single components for future applications in lighting fields.

Journal of Physical Chemistry Letters published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Related Products of imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Ibrahim, S. A. published the artcileColorimetric method for the estimation of antazoline, Application of N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, the publication is Indian Journal of Pharmacy (1974), 36(3), 73-5, database is CAplus.

A sensitive colorimetric method was developed for the determination of antazoline-HCl (I) [2508-72-7] in the pure state and in pharmaceutical preparations It depends on estimating the color produced when I was treated with nitrite. Thus, a 20 ml aliquot of I solution (stock solution contains 0.5% I-HCl in water) was treated with 4 ml NaNO2 solution (7.5% in concentrated H2SO4) 5 min at room temperature, and the solution was diluted to 50 ml with 15% aqueous AcONa. Absorbance was read within 10 min at 416 nm against a reagent blank. Data were given on the estimation of I by this method in pharmaceutical formulations. No interference was produced by phenylephrine-HCl [61-76-7], ephedrine-HCl [50-98-6], naphazoline-HCl [550-99-2], chlorobutanol [57-15-8], benzalkonium chloride, or polyethylene glycol [25322-68-3].

Indian Journal of Pharmacy published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C17H20ClN3, Application of N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Aweke, Bamlaku Semagne published the artcileA Bis-(carbone) Pincer Ligand and Its Coordinative Behavior toward Multi-Metallic Configurations, Recommanded Product: 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, the publication is Angewandte Chemie, International Edition (2022), 61(24), e202201884, database is CAplus and MEDLINE.

Carbones are divalent carbon(0) species that contain two lone pairs of electrons. Herein, authors have prepared the first known stable and isolable free bis-(carbone) pincer framework with a well-defined solid-state structure. This bis-(carbone) ligand is an effective scaffold for forming monometallic (Ni and Pd) and trinuclear heterometallic complexes with Au-Pd-Au, Au-Ni-Au, and Cu-Ni-Cu configurations. Sophisticated quantum-theor. analyses found that the metal-metal interactions are too weak to play a significant role in upholding these multi-metallic configurations; rather, the four lone pairs of electrons within the bis-(carbone) framework are the main contributors to the stability of the complexes.

Angewandte Chemie, International Edition published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Recommanded Product: 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem