Category: imidazoles-derivatives

Thermal properties of imidazolium ionic liquids was written by Ngo, H. L.;LeCompte, K.;Hargens, L.;McEwen, A. B.. And the article was included in Thermochimica Acta in 2000.SDS of cas: 157310-73-1 The following contents are mentioned in the article:

We investigated the thermal properties of several imidazolium salts using DSC and TGA/SDTA data. Many of these salts are liquids at sub-ambient temperatures These ionic liquids form glasses at low temperatures and have minimal vapor pressure up to their thermal decomposition temperature (>400°C). Thermal decomposition is endothermic with the inorganic anions and exothermic with the organic anions investigated. Halide anions drastically reduce the thermal stability of these salts (<300°C). We have observed that aluminum catalyzes the decomposition of the salts containing the inorganic fluoride anions. The imidazolium cations are thermally more stable than the tetraalkyl ammonium cations. This study involved multiple reactions and reactants, such as 1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1SDS of cas: 157310-73-1).

1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).SDS of cas: 157310-73-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Thermodynamic Properties of a series of closely related ionic liquids based on 1-alkyl-3-methylimidazolium hydrosulfate was written by Xu, Zhi-ce;Wang, Jian-ying;Wang, Xiao-ling;Hu, Yong-qi. And the article was included in Gaodeng Xuexiao Huaxue Xuebao in 2011.Application In Synthesis of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate The following contents are mentioned in the article:

The densities of a series of ionic liquids [C₄mim]HSO₄ (1-butyl-3-methylimdazolium hydrosulfate), [C₆mim]HSO₄ (1-hexyl-3-methylimdazolium hydrosulfate), [C₈mim]HSO₄ (1-octyl-3-methylimdazolium hydrosulfate) and [C₁mim]HSO₄ (1-decyl-3-methylimdazolium hydrosulfate) were determined from 293.15K to 343.15K. The coefficients of thermal expansion and mol. volume of the ionic liquids were calculated from the d. results. Standard entropy and lattice energy of the ionic liquids were calculated from the exptl. d. values using Glasser’s equation. The thermodn. properties of the ionic liquid were further discussed. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Application In Synthesis of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Application In Synthesis of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Indolent T cell lymphoma involving the central nervous system and successfully treated by bendamustine was written by Hui, Min;Chen, Miao. And the article was included in Annals of Hematology in 2022.Application In Synthesis of 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid The following contents are mentioned in the article:

Peripheral T-cell lymphoma, not otherwise unspecified (PTCL-NOS), was most common among the peripheral T-cell lymphomas (PTCL) subtypes. The central nervous system (CNS) is rarely involved as the primary site, making it especially challenging for diagnosis and treatment. The present report describes a rare case of indolent PTCL involving the central nervous system, bone marrow, s.c. tissue, and muscles, which was successfully treated by the bifunctional alkylating agent bendamustine and allogeneic hematopoietic stem cell transplantation. This report describes the first known experience of patients with indolent T cell lymphoma involving the central nervous system treated with bendamustine. This study involved multiple reactions and reactants, such as 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7Application In Synthesis of 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid).

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Application In Synthesis of 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A novel preparation of zirconium phosphate nanoparticle and its application in multi-component reactions was written by Hirbod, Karimi. And the article was included in Iranian Journal of Chemistry & Chemical Engineering in 2017.Computed Properties of C10H20N2O4S The following contents are mentioned in the article:

A novel method for the preparation of α-zirconium phosphate (ZrP) nanoparticles as an eco-friendly and recyclable heterogeneous catalyst was studied. Polyethylene glycol (PEG) was used as the organic matrix which produced a better dispersion of ZrP nanoparticles. The catalyst was characterized by several physicochem. techniques such as ICP-OES, XRD, TPD-NH3, pyridine-FTIR, BET, FTIR, TGA, SEM, and TEM. The acidic property of ZrP was studied in the synthesis of 2-amino-3-cyanopyridines. When the hexagonal ZrP nanoparticles were used as the catalyst, excellent yields were obtained. The catalyst was recovered and reused at least eight times without significant loss in its catalytic activity. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Computed Properties of C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Computed Properties of C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The Syntheses, Structures, Fluorescence Properties and Biological Activity of two Novel Zinc(II) Complexes Controlled by the Tripodal Imidazole Ligand was written by Gao, En-Jun;Zhang, Shaozhong;Meng, Yang;Zhao, Fu-Chen;Ma, Xiao-Yu;Jin, Hai-Tao;Liu, Si-Jia;Ge, Jing;Sun, Ya-Guang;Zhang, Wan-zhong;Zhu, Ming-Chang. And the article was included in Journal of Fluorescence in 2016.Product Details of 1374155-84-6 The following contents are mentioned in the article:

Two new zinc complexes, namely Zn(L¹)ClCH₂NO(1) and {Zn(L²)CH₂NO}_n N(CH₃)₃ ClO₄(2) (L¹ = 3,5-di(1H-imidazol-1-yl)pyridine L² = 1,3,5-tris(1-imidazolyl) benzene), have been synthesized, and characterized by IR spectra, elemental anal., and a single crystal X-ray diffraction. Fluorescence spectroscopy indicated that two complexes presented strong DNA binding affinity constants to fish sperm DNA (FS-DNA). Gel electrophoresis assay demonstrated the ability of the complex to cleave the HL-60 DNA. Apoptotic study showed the complex exhibited significant cancer cell(KB) inhibitory rate. This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Product Details of 1374155-84-6).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Product Details of 1374155-84-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A group contribution method to predict the melting point of ionic liquids was written by Lazzus, Juan A.. And the article was included in Fluid Phase Equilibria in 2011.Computed Properties of C8H15F6N2P The following contents are mentioned in the article:

The m.ps. of several families of ionic liquids were predicted with a simple group contribution method. A set of 200 ionic liquids was used to obtain the contributions for anion and cation groups. The optimum parameters of the method were obtained using a genetic algorithm-based on multivariate linear regression. Then, the melting temperatures of another 200 ionic liquids were predicted, and the results were compared with exptl. data available in the literature. The study shows that the proposed group contribution method represents an excellent alternative for the estimation of the m.p. of diverse ionic liquids from the knowledge of their mol. structure, with an average deviation of 7%. This study involved multiple reactions and reactants, such as 1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1Computed Properties of C8H15F6N2P).

1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Computed Properties of C8H15F6N2P

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Acidic-functionalized ionic liquid as an efficient, green, and metal-free catalyst for benzylation of sulfur, nitrogen, and carbon nucleophiles to benzylic alcohols was written by Chu, Xue-Qiang;Jiang, Ran;Fang, Yi;Gu, Zheng-Yang;Meng, Hua;Wang, Shun-Yi;Ji, Shun-Jun. And the article was included in Tetrahedron in 2013.COA of Formula: C10H20N2O4S The following contents are mentioned in the article:

A series of HSO4^– functionalized ILs was synthesized and used as efficient, green, and metal-free catalysts for benzylation. Notably, the catalytic system has wide substrate scopes and the ionic liquid catalysts were applied to investigate three different types of nucleophiles to give the desired benzylation products with moderate to excellent yields. Thus, benzylation of thiols, anilines, and indoles by benzylic alcs. was catalyzed by an acid-functionalized ionic liquid E.g., in presence of 1-methyl-3-pentylimidazolium hydrogen sulfate, benzylation of benzothiazole-2-thiol by 4-MeOC₆H₄CH₂OH gave 91% benzylic thioether (I). This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4COA of Formula: C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).COA of Formula: C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Heterologous SARS-CoV -2 vaccinations in patients with B-cell lymphoid malignancies was written by Ujjani, Chaitra;Greninger, Alexander L.;Shadman, Mazyar;Hill, Joshua A.;Lynch, Ryan C.;Warren, Edus H.;Gopal, Ajay K.. And the article was included in American Journal of Hematology in 2022.Recommanded Product: 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid The following contents are mentioned in the article:

This article deals about heterologous SARS-CoV-2 vaccinations in patients with B-cell lymphoid malignancies. The majority of patients subsequently received another mRNA vaccine for a total of four vaccinations. The median IgG, absolute lymphocyte count, and normal CD19+ B-cell counts were 597 mg/dL (range 180-1007), 0.97-103/mL (range 0.61-2.56), and 0.6 cells/mL (range 0-121), resp. Nucleocapsid antibody was nonreactive in all patients, indicating no evidence of prior SARS-CoV-2 infection. A number of variables such as type of B-cell directed therapy, length of and time from exposure, sequence of and duration between vaccinations, and underlying disease biol. may have had impact. This study involved multiple reactions and reactants, such as 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7Recommanded Product: 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid).

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Recommanded Product: 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Improving effect of Co(II)-coordination polymers on pre-eclampsia symptoms by increasing the Elabela was written by Chen, Xue-Jun;Tao, Xiao-Ling;Li, Lan-Fang;Lu, Wen-Hao;Wang, Ya-Ping. And the article was included in Inorganic and Nano-Metal Chemistry in 2022.Name: 3,5-Di(1H-imidazol-1-yl)pyridine The following contents are mentioned in the article:

Two Co(II)-coordination polymers modified by a rigid amine 3,5-bis(imidazole-1-yl)pyridine (BIP), [Co₂(HPO₃)₂(BIP)]·H₂O () and [Co₃(HPO₃)₃(BIP)(H₂O)]·H₂O (), were solvothermally prepared Their improving effect on pre-eclampsia symptoms was evaluated and the related mechanism was explored at the same time. Firstly, the ELISA detection kits were performed to measure the levels of the Elabela in the plasma after indicated treatment. In addition to this, the urine protein content of pregnant mice after compound treatment was also determined with Braford protein content detection kit. This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Name: 3,5-Di(1H-imidazol-1-yl)pyridine).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Name: 3,5-Di(1H-imidazol-1-yl)pyridine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of 1,2-diaryl- and 1-aryl-2-alkylimidazoles with sterically demanding substituents was written by Micksch, Maik;Tenne, Mario;Strassner, Thomas. And the article was included in European Journal of Organic Chemistry in 2013.Electric Literature of C21H24N2 The following contents are mentioned in the article:

1,2-Diarylimidazoles are an important class of compounds They are frequently used as ligands for photophys. active metal complexes and also display physiol. activity. We developed a new, high-yielding procedure for the synthesis of 1,2-diaryl-substituted imidazoles with sterically demanding substituents at the resp. ortho positions by starting from com. available anilines and benzoic acids through the corresponding acid chlorides. The metal-free method provides access to a variety of different substituents on the Ph rings at N-1 and C-2 as well as at the 4,5-positions of the imidazole backbone. Our new method is also suitable for the preparation of 1-aryl-2-alkylimidazoles. This study involved multiple reactions and reactants, such as 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6Electric Literature of C21H24N2).

1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Electric Literature of C21H24N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem