Category: imidazoles-derivatives

LC analysis of hexafluorophosphate on a monolithic column: Application to the analysis of ionic liquids was written by Yang, Ling;Yu, Hong;Li, Siwen;Zhou, Shuang. And the article was included in Chromatographia in 2010.Application of 157310-73-1 The following contents are mentioned in the article:

A silica-based monolithic column with tetrabutylammonium hydroxide-phthalic acid-acetonitrile as mobile phase was used for LC anal. of hexafluorophosphate with direct conductivity detection. The effects of mobile phase composition, column temperature, and flow rate on retention of hexafluorophosphate were studied and the optimum chromatog. conditions were selected. Common anions and tetrafluoroborate did not interfere with anal. of hexafluorophosphate. The detection limit (S/N = 3) for hexafluorophosphate was 6.2 mg L^-1. Relative standard deviation (n = 5) for peak area was 0.1%. The method was successfully used for anal. of hexafluorophosphate in ionic liquids This study involved multiple reactions and reactants, such as 1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1Application of 157310-73-1).

1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Application of 157310-73-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Suzuki-Miyaura C-C coupling reactions catalysed by a homogeneous and nanosilica supported palladium(II) N-heterocyclic carbene complex derived from 3,5-di(1-imidazolyl)pyridine was written by Pahlevanneshan, Zari;Moghadam, Majid;Mirkhani, Valiollah;Tangestaninejad, Shahram;Mohammadpoor-Baltork, Iraj;Rezaei, Saghar. And the article was included in New Journal of Chemistry in 2015.Name: 3,5-Di(1H-imidazol-1-yl)pyridine The following contents are mentioned in the article:

A new Pd N-heterocyclic carbene complex using 3,5-di(1H-imidazol-1-yl)pyridine as a precursor was prepared The complex was immobilized on 3-chloropropylated nanosilica as a support and characterized by FTIR spectroscopy, TGA, field emission SEM, energy dispersive x-ray anal., TEM and elemental anal. The prepared catalyst was used as a heterogeneous catalyst in the Suzuki-Miyaura coupling reactions of various aryl halides with phenylboronic acid and the corresponding biphenyls were being produced in a high yield. The catalyst was recyclable under aerobic conditions without significant loss of activity. Also, the catalytic activity of the homogeneous catalyst was studied. This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Name: 3,5-Di(1H-imidazol-1-yl)pyridine).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Name: 3,5-Di(1H-imidazol-1-yl)pyridine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Treatment strategy for patients with relapsed/refractory classical Hodgkin lymphoma was written by Yoshida, Isao. And the article was included in Ketsueki Naika in 2021.Related Products of 16506-27-7 The following contents are mentioned in the article:

A review. Classical Hodgkin lymphoma (CHL) is a type of lymphoma that is sensitive to chemotherapy and can provide an R-stage solution in many cases. Single-center pre-examination study of combination treatment with bendamustine, nivolumab for patients who became refractory to treatment with nivolumab. It will be performed in consideration of the disease, organ function, and the drug packing used in the previous treatment, but if the reduction effect is obtained by the rescue chemotherapy, the self-implantation combined large-scale chemotherapeutic method (ASCT) is used as a remedy treatment. This review outlines the treatment of relapsed/refractory classical Hodgkin lymphoma with a focus on brentuximab vedotin and ΡD-1 antibodies, and the usefulness of autologous stem cell transplant in therapeutic cases. This study involved multiple reactions and reactants, such as 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7Related Products of 16506-27-7).

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Related Products of 16506-27-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Novel quaternary ammonium ionic liquids and their use as dual solvent-catalysts in a hydrolytic reaction was written by Weng, Jianyang;Wang, Congmin;Li, Haoran;Wang, Yong. And the article was included in Green Chemistry in 2006.Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate The following contents are mentioned in the article:

Ionic liquids (ILs) are no longer just a class of esoteric compounds, but are proving to be valuable and useful in a multitude of different applications. Herein, novel quaternary ammonium ionic liquids have been synthesized and characterized. These ionic liquids are Bronsted acidic, available from cheap raw materials and easy to prepare They have been used both as a catalyst and environmentally benign solvent for the hydrolytic reaction of 1,1,1,3-tetrachloro-3-phenylpropane, eliminating the need for a volatile organic solvent and addnl. catalyst. The results clearly demonstrate that these ILs can be easily separated and reused without losing their activity and quality. Also, the yields obtained with this methodol. are significantly increased in comparison with those reported in organic solvents to date. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Ionic liquids as novel catalysts for methane conversion under a DC discharge plasma was written by Yu, M.;Zhai, L. Y.;Zhou, Q.;Li, C. P.;Zhang, X. L.. And the article was included in Applied Catalysis, A: General in 2012.Product Details of 478935-29-4 The following contents are mentioned in the article:

Nine imidazolium-based ionic liquids (ILs) were investigated as novel catalysts for methane conversion in a d.c. (DC) discharge plasma reactor. The conversion of methane increased from 21.2% to 43.6% in the plasma system when the C₆MIMHSO₄ IL was used as a catalyst, C₆MIMBF₄ successfully achieved 91.0% selectivity for C₂ hydrocarbons. The results of the optical emission spectroscopy indicate that the intensity of the C₂, CH, H, C⁺, and C active species from methane decomposition increased when C₆MIMHSO₄, C₆MIMCF₃COO, and C₆MIMBF₄ were introduced into the plasma system. FTIR anal. indicates that C₆MIMBF₄ is steady in the DC discharge plasma. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Product Details of 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Product Details of 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Reduced bendamustine for elderly patients with follicular lymphoma was written by Masamoto, Yosuke;Shimura, Arika;Kurokawa, Mineo. And the article was included in Annals of Hematology in 2022.Application of 16506-27-7 The following contents are mentioned in the article:

As the outcome of follicular lymphoma (FL), the most common subtype of indolent non-Hodgkin’s lymphoma, has been improved since the introduction of immunochemotherapy, non-lymphoma-related causes of death, including infections, have become increasingly important. Bendamustine is widely used as one of the key drugs of the standard therapy, and characterized by long-term lymphocytopenia as a frequent adverse event, rendering the patients especially vulnerable to various infections. In this study, authors aims to clarify the short-term outcome and toxicities of the reduced bendamustine. Patients underwent bendamustine treatment without dose reduction from the original plan. Elderly patients in this cohort showed promising outcomes with a similar rate of toxicities except for lymphocytopenia. This study involved multiple reactions and reactants, such as 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7Application of 16506-27-7).

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Application of 16506-27-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis and preliminary evaluation of curcumin analogues as cytotoxic agents was written by Zhang, Qin;Zhong, Ying;Yan, Lin-Na;Sun, Xun;Gong, Tao;Zhang, Zhi-Rong. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2011.Electric Literature of C11H10N2O2 The following contents are mentioned in the article:

A series of curcumin analogs with different substituents at the 4-position of the Ph group were synthesized and screened for in vitro cytotoxicity against a panel of human cancer cell lines. Several novel curcumin analogs, especially I and II, exhibited selective and potent cytotoxic activity against human epidermoid carcinoma cell line A-431 and human glioblastoma cell line U-251, implying their specific potential in the chemoprevention and chemotherapy of skin cancer and glioma. The preliminary SAR information extracted from the results suggested that introduction of appropriate substituents to the 4′-positions could be a promising approach for the development of new cytotoxic curcumin analogs with special selectivity for A-431 and U-251 cell lines. This study involved multiple reactions and reactants, such as 4-(1H-Imidazol-1-yl)-3-methoxybenzaldehyde (cas: 870837-70-0Electric Literature of C11H10N2O2).

4-(1H-Imidazol-1-yl)-3-methoxybenzaldehyde (cas: 870837-70-0) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Electric Literature of C11H10N2O2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Ionic liquid promoted cyclocondensation reactions to the formation of isoxazoles, pyrazoles and pyrimidines was written by Moreira, Dayse N.;Longhi, Kelvis;Frizzo, Clarissa P.;Bonacorso, Helio G.;Zanatta, Nilo;Martins, Marcos A. P.. And the article was included in Catalysis Communications in 2010.Category: imidazoles-derivatives The following contents are mentioned in the article:

A simple one-pot procedure to obtain a series of five- and six-membered heterocycles, e. g., I and II in three different ionic liquids ([BMIM][BF₄], [BMIM][OH] and [HMIM][HSO₄]) is described. The synthetic protocol involves the reaction between β-enamino ketone derived from 1,4-diacetylbenzene and hydroxylamine, hydrazines (R¹NHNH₂, where R¹ = H, Ph, 4-O₂N-Ph, 2,4-(O₂N)₂-Ph, C₆F₅, CO₂Me, CONH₂, CH₂CH₂OH, t-Bu) or amidines (R²C(NH)NH₂, where R² = NH₂, Ph), furnishing bis-isoxazoles, bis-pyrazoles and bis-pyrimidines in good yields and short reaction times. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Category: imidazoles-derivatives).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Zinc coordination polymers with rigid dicarboxylates and semirigid 3,5-bis(imidazole-1-yl) pyridine: syntheses, structural topologies, and luminescent properties was written by Xu, Jiakun;Sun, Xiaochun;Ju, Caixia;Sheng, Jun;Wang, Fang;Sun, Mi. And the article was included in Journal of Coordination Chemistry in 2013.Formula: C11H9N5 The following contents are mentioned in the article:

Two metal coordination polymers, {[Zn(bpdc)(bip)]·2H₂O}_n (1) and [Zn(tdc)(bip)] (2) [H₂bpdc (5) = biphenyl-4,4′-dicarboxylate, H₂tdc (7) = thiophene-2,5-dicarboxylate, bip (6) = 3,5-bis(imidazole-1-yl)pyridine], were synthesized and characterized by IR, elemental anal., XRD, and x-ray single-crystal diffraction. In, bpdc and bip link Zn(II) ions into a corrugated 2D layer. The corrugated 2D layers polycatenate each other, yielding a 2Dâ†?D polycatenation net. In, dinuclear Zn(II) units are formed by bip and further connected by tdc to construct a 2D 3-connected framework. The luminescent properties of and were studied in the solid state at room temperature This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Formula: C11H9N5).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Formula: C11H9N5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The intrinsic anodic stability of several anions comprising solvent-free ionic liquids was written by Koch, V. R.;Dominey, L. A.;Nanjundiah, C.;Ondrechen, M. J.. And the article was included in Journal of the Electrochemical Society in 1996.Electric Literature of C8H15F6N2P The following contents are mentioned in the article:

Salts of the form 1,2-dimethyl-3-propylimidazolium X [where X = AsF₆^–, PF₆^–, (CF₃SO₂)₂N^–, and (CF₃SO₂)₃C^–] were prepared and purified. Linear sweep voltammetry was conducted at 80°, a temperature at which all four salts were molten, at Pt, W, and glassy C working electrodes. The intrinsic anodic stability of these anions was in the order (CF₃SO₂)₃C^– > (CF₃SO₂)₂N^– approx. AsF₆^– > PF₆^–. These exptl. solution-phase oxidation potentials correlated well with gas-phase HOMO energies calculated by an ab initio technique. This study involved multiple reactions and reactants, such as 1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1Electric Literature of C8H15F6N2P).

1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Electric Literature of C8H15F6N2P

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem