Category: imidazoles-derivatives

Two novel Co (II) bifunctional MOFs: Syntheses and applications in photocatalytic degradation of dyes and electrocatalytic water oxidation was written by Cui, Guanning;Liu, Wenbo;Wang, Lulu;Wu, Ruixue;Bi, Caifeng;Zhang, Dongmei;Fan, Yuhua. And the article was included in Journal of Solid State Chemistry in 2021.Safety of 3,5-Di(1H-imidazol-1-yl)pyridine The following contents are mentioned in the article:

Two novel Co (II) MOFs based on 5-(4-(imidazolyl-1-yl)phenyl) isophthalic acid (H₂L), [Co(L)(tib)(H₂O)₂]_n (CP 1) and [Co(L)(bip)_0.5]_n (CP 2) (tib = 1,3,5-tris (1-imidazolyl) benzene, bip = 3,5-bis(1-imidazolyl) pyridine ether) were synthesized under solvothermal conditions and characterized by powder x-ray diffraction, single crystal x-ray diffraction. The photodegradation studies demonstrate that CPs 1–2 show high-efficiency degradation of MV (Methyl violet), and the mechanism studies demonstrate that the main active species are ·OH radicals. Meanwhile, electrochem. studies demonstrate that CPs 1–2 can catalyze water oxidation under alk. conditions, and CPs 1–2 only need the overpotential of 348 mV-760 mV to deliver the c.d. of 1 mA cm^-2. This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Safety of 3,5-Di(1H-imidazol-1-yl)pyridine).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Safety of 3,5-Di(1H-imidazol-1-yl)pyridine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Highly efficient preparation of 5-hydroxymethylfurfural from sucrose using ionic liquids and heteropolyacid catalysts in dimethyl sulfoxide-water mixed solvent was written by Yu, Song-Bai;Zang, Hong-Jun;Yang, Xiao-Li;Zhang, Ming-Chuan;Xie, Rui-Rui;Yu, Pei-Fei. And the article was included in Chinese Chemical Letters in 2017.Related Products of 478935-29-4 The following contents are mentioned in the article:

Several types of ILs and solid acids were used as catalysts in one-pot conversion of sucrose to 5-hydroxymethylfurfural (abbreviated as 5-HMF) in a DMSO/water mixed solvent under hydrothermal conditions. A remarkable 5-HMF yield of 91.8% was achieved catalyzed by the cesium salt of dodecatungstophosphoric acid (Cs_2.3H_0.7PW₁₂O₄₀) within 3 h at 180 °C. The ionic liquid N-methylimidazolium hydrogen sulfate ([Hmim][HSO₄]) gave the 5-HMF in 82.0% yield from sucrose. To the best of our knowledge, it was almost the highest yield of HMF from sucrose by now. Various reaction parameters including reaction temperature and time and catalyst dosage were optimized. A possible mechanism for this catalytic process was proposed. Furthermore, fructose and glucose were also investigated, good yields of 5-HMF was obtained resp. This increases the possibility of large-scale production of 5-HMF from carbohydrates. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Related Products of 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Related Products of 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of phenethyl acetate with acidic ionic liquid as catalyst was written by Liu, Xiaoyu. And the article was included in Henan Huagong in 2015.Electric Literature of C10H20N2O4S The following contents are mentioned in the article:

Phenethyl acetate (PEAC) is synthesized by using an acidic ionic liquid n-hexyl-methylimidazolium bisulfate abbreviated as [n-C₆Im][HSO₄] as catalyst. By studying on the effect of various factors on the conversion rate, the optimal conditions include 1:1.2 2-Ph ethanol/vinyl acetate, the ionic liquid 5wt%, 140°C reaction temperature and 6 h of reaction time, the conversion of PEAC is 91.8%. After the reaction completed, the [n-C₆Im][HSO₄] could be used for a new synthesis of PEAC. Although the conversion slightly reduced after the [n-C₆Im][HSO₄] was reused for four times, its catalytic activity could reach to original level by adding suitable sulfuric acid. Compared with classical strong acid catalysts, the reaction system using ionic liquid [n-C₆Im][HSO₄] as catalyst offers many advantages of good color of PPAE, easy recovery, and reuse of the catalyst. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Electric Literature of C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Electric Literature of C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A rapid Fourier transform infrared spectroscopic method for analysis of certain proton pump inhibitors in binary and ternary mixtures was written by Khashaba, Pakinaz Y.;Ali, Hassan Refat H.;El-Wekil, Mohamed M.. And the article was included in Spectrochimica Acta in 2018.Electric Literature of C18H20N3NaO3S The following contents are mentioned in the article:

A simple and non-destructive FTIR method was used to determine certain proton pump inhibitors (PPIs) in binary and ternary mixtures Proton pump inhibitors (PPIs); omeprazole (OMZ), esomeprazole (EZM), lansoprazole (LAN), pantoprazole sodium (PAN sodium) and rabeprazole sodium (RAB sodium) in binary mixture with domperidone (DOM) and ternary mixture of OMZ, clarithromycin (CLM) and tinidazole (TNZ) were determined in the solid-state by FTIR spectroscopy for the first time. The method was validated according to ICH-guidelines where linearity was ranged from 20 to 850 μg/g and 20-360 μg/g for PPIs and DOM, resp. in binary mixtures and 10-400, 100-8000 and 150-14,000 μg/g for OMZ, CLM and TNZ, resp. Limits of detection were found to be 6-100 and 9-100 μg/g for PPIs and DOM, resp. and 4, 40 and 50 μg/g for OMZ, CLM and TNZ, resp. The method was applied successfully for determination of the cited drugs in their resp. pharmaceutical dosage forms. This study involved multiple reactions and reactants, such as Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6Electric Literature of C18H20N3NaO3S).

Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Electric Literature of C18H20N3NaO3S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A Simple and Practical Synthesis of 2-Aminoimidazoles was written by Little, Thomas L.;Webber, Stephen E.. And the article was included in Journal of Organic Chemistry in 1994.Name: 4-Phenyl-1H-imidazol-2-amine hemisulfate The following contents are mentioned in the article:

A new and simple two-step procedure to synthesize 2-aminoimidazoles (2-AI’s) from readily available materials has been developed. The cyclization reaction of α-halo ketones RCOCHR¹X [R = Me, Et, CMe₃, Ph, 4-BrC₆H₄, etc., R¹ = H, Me, Ph, RR¹ = (CH₂)₃, (CH₂)₄, X = Cl, Br] and N-acetylguanidine in acetonitrile (MeCN) at reflux, or in DMF at ambient temperature, gives 4(5)-substituted and 4,5-disubstituted N-(1H-imidazol-2-yl)acetamides I, which are then hydrolyzed to their resp. 2-AI’s. In general, the purified products were isolated in good yields. We have prepared several examples and have demonstrated the usefulness of this method by its application in the total synthesis of 2-aminohistamine, an interesting histamine analog, and oroidin (II), a marine natural product isolated from various sponges. This study involved multiple reactions and reactants, such as 4-Phenyl-1H-imidazol-2-amine hemisulfate (cas: 160072-56-0Name: 4-Phenyl-1H-imidazol-2-amine hemisulfate).

4-Phenyl-1H-imidazol-2-amine hemisulfate (cas: 160072-56-0) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Name: 4-Phenyl-1H-imidazol-2-amine hemisulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A method for determination of Hammett acidity function (H₀) of ionic liquid/sulfuric acid binary mixtures was written by Zhou, Fei;Zhang, Yuan;Zhang, Tao;Liang, Bin;Tang, Sheng-wei. And the article was included in Tianranqi Huagong in 2013.Recommanded Product: 478935-29-4 The following contents are mentioned in the article:

A method for determining the Hammett acidity function (H₀) of ionic liquid/H₂SO₄ binary mixtures was established by analyzing the measuring principal and choosing the suitable media for protonating or unprotonating the indicators. 2-Benzoylnaphthalene, 6-bromo-2, 4-dinitroaniline, anthraquinone and 4-nitrotoluene were used as indicators for different scopes of H₀. The reliability of this method was evaluated by comparing the exptl. H₀ and the literature H₀ of H₂SO₄ solution, and the relative deviation was less than 0.5%. The method was successfully used to determine the H₀ of the ([HMIm][HSO₄])/H₂SO₄ with a IL mass fraction of up to 19% and the ([MBSIm][HSO₄])/H₂SO₄ with a IL mass fraction of up to 15%. The relative deviation of three parallel measurements was less than 0.3%. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Recommanded Product: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Recommanded Product: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Highly selective synthesis for 4,4′-bisphenol F from phenol and formaldehyde catalyzed with [C₄min][HSO₄] ionic liquid was written by Wang, Danfeng;He, Zhicheng;Wu, Zhimin;Tan, Ying;Li, Yongfei;Liu, Yuejin. And the article was included in Chinese Journal of Chemical Engineering in 2016.Category: imidazoles-derivatives The following contents are mentioned in the article:

The effects of N-methylimidazole cation [C_nmin] with different alkyl chain lengths, the types of cations and anions of ionic liquids and the reaction parameters on the catalytic activity and the selectivity for 4,4′-bisphenol F were investigated. The hydrogen bonding between the hydroxyl of phenol and the C2-position hydrogen of imidazole moiety in hydrophilic imidazole-based ionic liquid has important influence on the selectivity for 4,4′-bisphenol F, and under the conditions of the molar ratio of phenol/[C₄min][HSO₄] 1:1, reaction temperature 65°C and the theor. molar ratio of phenol/formaldehyde 2:1, the selectivity for 4,4′-bisphenol F reached 69.1%. Compared with the high phenol/formaldehyde ratio reported in literatures, the low molar ratio of phenol/formaldehyde and the low reaction temperature could greatly reduce energy consumption, and had important significance for industrial application. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Category: imidazoles-derivatives).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Two dimensional coordination polymers based on 3,5-di(1H-imidazol-1-yl)pyridine and their fluorescence properties was written by Zhang, Hao;Zhu, Zhao Qiang;Zhou, Fu-Hou;Redshaw, Carl;Chen, Kai;Xu, Jing. And the article was included in Journal of Molecular Structure in 2020.Application In Synthesis of 3,5-Di(1H-imidazol-1-yl)pyridine The following contents are mentioned in the article:

The solvothermal synthesis of three new 2D MOFs is reported. From the reaction of 3,5-di(1H-imidazol-1-yl)pyridine (dip) and the metal salts Co(NO₃)₂·6H₂O, Cd(NO₃)₂·4H₂O or Zn(NO₃)₂·4H₂O, the three MOFs [Co(dip)₂(SCN)₂] (1), {[Cd(dip)₂(H₂O)₂]·(NO₃)₂} (2), {[Zn(dip)₂(H₂O)₂]·(ClO₄)₂} (3) were obtained. For these 2D MOFs, all the metal ions adopt a six-coordinate octahedral geometry with axial coordination sites occupied by SCN^– or water mols. The SCN^–/water ligands were all mono-coordinate and led to layered MOF structures. Furthermore, the fluorescence properties of 2 and 3 have been investigated. This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Application In Synthesis of 3,5-Di(1H-imidazol-1-yl)pyridine).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Application In Synthesis of 3,5-Di(1H-imidazol-1-yl)pyridine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Determination of Proton Pump Inhibitors by Spectrophotometric, Chromatographic and by Hyphenated Techniques: A Review was written by Joshi, Aditya A.;Nerkar, Pankaj P.. And the article was included in Critical Reviews in Analytical Chemistry in 2021.SDS of cas: 117976-90-6 The following contents are mentioned in the article:

A review. A detailed review to analyze the anti ulcer proton pump inhibitor (PPI) drugs, particularly for determination of their concentration percentage (assay) by anal. methods developed on anal. instruments i.e., UV visible Spectrophotometer, High Performance Liquid Chromatog., Ultra Performance Liquid Chromatog., and Hyphenated techniques. The review includes literature survey of PPI drugs namely omeprazole (OPZ), lansoprazole (LPZ), pantoprazole (PPZ) rabeprazole (RPZ), dexlansoprazole (DLPZ), esomeprazole (EPZ), dexrabeprazole (DRPZ), ilaprazole (IPZ), and tenatoprazole (TPZ). The examined literature survey addressed chromatog. (HPLC and UPLC) and UV visible spectrophotometric methods with LC-MS/MS methods used in pure forms, pharmaceutical formulations, and human plasma and other biol. fluids for their estimation In case of validation parameters mostly Linearity, Recovery study, LOD and LOQ was considered and mentioned. This study involved multiple reactions and reactants, such as Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6SDS of cas: 117976-90-6).

Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).SDS of cas: 117976-90-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A novel chemoenzymatic synthesis of propyl caffeate using lipase-catalyzed transesterification in ionic liquid was written by Pang, Na;Gu, Shuang-Shuang;Wang, Jun;Cui, Hong-Sheng;Wang, Fang-Qin;Liu, Xi;Zhao, Xing-Yu;Wu, Fu-An. And the article was included in Bioresource Technology in 2013.Computed Properties of C10H20N2O4S The following contents are mentioned in the article:

Pr caffeate has the highest antioxidant capacity in the caffeate alkyl esters family, but industrial production of Pr caffeate is hindered by low yields using either the chem. or enzymic catalysis method. To set up a high-yield process for obtaining Pr caffeate, a novel chemoenzymic synthesis method using lipase-catalyzed transesterification of an intermediate Me caffeate or Et caffeate and 1-propanol in ionic liquid was established. The maximum Pr caffeate yield of 98.5% was obtained using lipase-catalyzed transesterification under the following optimal conditions: Novozym 435 as a biocatalyst, [Bmim][CF₃SO₃] as a medium, a molar ratio of Me caffeate to 1-propanol of 1:5, a mass ratio of Me caffeate to lipase of 1:20, and a reaction temperature of 60 °C. The two-step conversion of caffeic acid to Pr caffeate via Me caffeate is an efficient way to prepare Pr caffeate with an overall yield of 82.7%. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Computed Properties of C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Computed Properties of C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem