Category: imidazoles-derivatives

Synthesis of dioctyl succinate catalyzed by task-specific ionic liquids under microwave irradiation and electrical heating was written by Long, Yu-lin;Chen, Bing;Yang, Jun;Yin, Wan-xiang. And the article was included in Huaxue Yanjiu Yu Yingyong in 2012.Computed Properties of C10H20N2O4S The following contents are mentioned in the article:

A series of task-specific ionic liquids(TSILs) that bear an alkane sulfonic acid group were synthesized. Esterification of succinic acid with octanol was investigated using these TSILs as catalysts in both microwave irradiation and traditional heating ways. Effect of the anion and cation of the TSILs on catalytic performance was also investigated. Compared with elec. heating way, TSILs exhibited an enhanced reaction efficiency and short reaction time under microwave irradiation Effect of catalyst amount, reaction time and the acid-to-alc. ratio on conversion of succinic acid was systematically investigated. The results showed that the conversion of succinic acid reached 95.74% by using[PSPy]HSO₄ as the catalyst under succinic acid/octanol molar ratio of 1:4, succinic acid mass fraction of 3wt% in TSILs, reaction temperature of 150°C, reaction time of 15 min and power of 400W. In addition, the [PSPy]HSO₄ exhibited excellent stability and catalytic activity. It could be reused six times without considerable loss of activity and still had a conversion of 93.58%. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Computed Properties of C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Computed Properties of C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Effects of cations and anions of ionic liquids on the production of 5-hydroxymethylfurfural from fructose was written by Shi, Chunyan;Zhao, Yuling;Xin, Jiayu;Wang, Jinquan;Lu, Xingmei;Zhang, Xiangping;Zhang, Suojiang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2012.Safety of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate The following contents are mentioned in the article:

Ionic liquids (ILs) with different cations and anions were used to study the effects on 5-hydroxymethylfurfural (HMF) preparation It was found that both aggregations of cations and hydrogen bonds of anions with fructose played important roles. Mol. dynamics simulations were also performed to explain the exptl. results. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Safety of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Safety of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Gastroprotective delivery of rabeprazole sodium along with metoclopramide hydrochloride using treated agar was written by Ratnakar, Raikar Prasiddhi;Pankaj, Gajare;Santoshi, Naik. And the article was included in International Journal of Pharmacy and Biological Sciences in 2021.Synthetic Route of C18H20N3NaO3S The following contents are mentioned in the article:

Particle engineering is a technique of phys. modification of the excipient at sub-particle level without altering chem. properties to achieve desired functionality. For development of immediate layer of Metoclopramide Hydrochloride Treated Agar was used as disintegrating agent and was compared with untreated agar. This study involved multiple reactions and reactants, such as Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6Synthetic Route of C18H20N3NaO3S).

Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Synthetic Route of C18H20N3NaO3S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Clauson Kaas pyrrole synthesis catalyzed by acidic ionic liquid under microwave irradiation was written by Aydogan, Feray;Yolacan, Cigdem. And the article was included in Journal of Chemistry in 2013.Application of 478935-29-4 The following contents are mentioned in the article:

A new procedure to synthesize N-substituted pyrroles by Clauson-Kaas reaction of amines with 2,5-dimethoxytetrahydrofuran catalyzed by acidic ionic liquid under microwave irradiation was developed. This procedure provides several advantages, such as high yield, clean product formation, and short reaction time. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Application of 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Application of 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Crystal structure of a diaqua-bis(3,5-di(1H-imidazol-1-yl)pyridine-κN)-bis(2-(4-carboxy-phenyl)acetato-κO]manganese(II), C₄₀H₃₆MnN₁₀O₁₀ was written by Ju, Feng-Yang;Guo, Wen-Bo;Li, Yun-Ping. And the article was included in Zeitschrift fuer Kristallographie – New Crystal Structures in 2017.Electric Literature of C11H9N5 The following contents are mentioned in the article:

C₄₀H₃₆MnN₁₀O₁₀, monoclinic, P2₁/c (number 14), a = 21.8966(12) Å, b = 7.2586(4) Å, c = 12.2346(6) Å, β = 98.232(1)°, V = 1924.52(18) ų, Z = 2, R_gt(F) = 0.0327, wR_ref(F²) = 0.0847, T = 296(2) K. This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Electric Literature of C11H9N5).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Electric Literature of C11H9N5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of tri(indolyl)methanes mediated by acidic ionic liquid was written by Gu, Da-Gong;Ji, Shun-Jun. And the article was included in Chinese Journal of Chemistry in 2008.Category: imidazoles-derivatives The following contents are mentioned in the article:

Various tri(indolyl)methanes, e.g., I (R = H, Me, NO₂, PhCH₂O), were synthesized by condensation of indole and its derivatives with indole-3-carboxaldehydes using acidic ionic liquids [hmim]HSO₄/EtOH as an efficient and green catalyst system. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Category: imidazoles-derivatives).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of 3,4,6,7,9,10-hexahydro-9-(aryl)-1,8(2H,5H)-acridinedione derivatives in the presence of ionic liquids was written by Tang, Ran-xiao;Yang, Xu-zhe;He, Hong-yan;Ma, Jing-jun;Wang, Chun;Lin, Jing. And the article was included in Huaxue Yanjiu Yu Yingyong in 2007.Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate The following contents are mentioned in the article:

A series of 9-(aryl)acridinedione derivatives was synthesized via a condensation reaction of aromatic aldehydes, 1,3-cyclohexanedione or 5,5-dimethyl-1,3-cyclohexanedione and ammonium acetate promoted by acidic ionic liquids This proposed method was simple, efficient and co- friendly. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Name: 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Determination of the structure of 2-methylimidazo[4,5-c]pyridine glycosides was written by Miroshnichenko, N. S.;Kovalenko, A. S.;Stetsenko, A. V.. And the article was included in Ukrainskii Khimicheskii Zhurnal (Russian Edition) in 1974.Related Products of 52538-09-7 The following contents are mentioned in the article:

Imidazopyridine glycosides (I; R = tri-O-acetyl-β-D-ribopyranosyl, β-D-ribopyranosyl, tri-O-acetyl-β-D-xylopyranosyl β-D-xylopyranosyl, tetra-O-acetyl-β-D-galactopyranosyl, β-D-galactopyranosyl) were prepared by known methods in 49-86%yields and their structures confirmed by NMR. This study involved multiple reactions and reactants, such as 2,3-Dimethyl-3H-imidazo[4,5-c]pyridine (cas: 52538-09-7Related Products of 52538-09-7).

2,3-Dimethyl-3H-imidazo[4,5-c]pyridine (cas: 52538-09-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Related Products of 52538-09-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Willgerodt reaction in a series of imidazopyridine derivatives was written by Yutilov, Yu. M.;Shcherbina, L. I.. And the article was included in Zhurnal Organicheskoi Khimii in 1996.Related Products of 52538-09-7 The following contents are mentioned in the article:

The Willgerodt reaction of 2-methylimidazopyridines with aniline and sulfur gave imidazopyridinecarbothioanilides such as I (R = Me, benzyl, Ph, H; R¹ = H, Br). Intramol. versions of this reaction gave tetracyclic products, e.g., II. This study involved multiple reactions and reactants, such as 2,3-Dimethyl-3H-imidazo[4,5-c]pyridine (cas: 52538-09-7Related Products of 52538-09-7).

2,3-Dimethyl-3H-imidazo[4,5-c]pyridine (cas: 52538-09-7) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Related Products of 52538-09-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Crystal structure of 3,5-bis(imidazole-1-yl)pyridine, C₁₁H₉N₅ was written by Zhou, Hongyan. And the article was included in Zeitschrift fuer Kristallographie – New Crystal Structures in 2015.Related Products of 1374155-84-6 The following contents are mentioned in the article:

C₁₁H₉N₅, monoclinic, P2₁/c (number 14), a = 14.15(1) Å, b = 3.783(3) Å, c = 18.09(2) Å, β = 92.28(2)°, V = 968.0 ų, Z = 4, R_gt(F) = 0.0517, wR_ref(F²) = 0.1504, T = 296 K. This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Related Products of 1374155-84-6).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Related Products of 1374155-84-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem