Category: imidazoles-derivatives

Multiple widespread fixed drug eruption caused by rabeprazole. was written by Gupta, S;Gupta, S;Mahendra, A;Yadav, A. And the article was included in Journal of postgraduate medicine in 2020.HPLC of Formula: 117976-90-6 The following contents are mentioned in the article:

Fixed drug eruption is one of the most common forms of cutaneous adverse drug reactions. Analgesics and antibiotics are the most common drugs causing fixed drug eruption. Here, we report a case of multiple widespread fixed drug eruption caused by rabeprazole. This study involved multiple reactions and reactants, such as Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6HPLC of Formula: 117976-90-6).

Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.HPLC of Formula: 117976-90-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Preparation of aniline from nitrobenzene in ionic liquids was written by Li, Wei;Wang, Yu;Dai, Li-yi. And the article was included in Hecheng Huaxue in 2010.HPLC of Formula: 478935-29-4 The following contents are mentioned in the article:

Ionic liquids were used as solvents in a reduction of nitrobenzene mediated by hydrazine hydrate to provide aniline. Optimized reaction conditions were determined and the synthesis of the target compound was achieved in 96.0% yield. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4HPLC of Formula: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. HPLC of Formula: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Hemolytic crisis due to Covid-19 vaccination in a woman with cold agglutinin disease was written by Perez-Lamas, Lucia;Moreno-Jimenez, Gemma;Tenorio-Nunez, Maria C.;Velazquez-Kennedy, Kyra;Jimenez-Chillon, Carlos;Astibia-Mahillo, Beatriz;Nunez-Torron, Claudia;Garcia-Gutierrez, Valentin;Jimenez-Martin, Ana;Valles-Carboneras, Ana;Lopez-Jimenez, Javier F.. And the article was included in American Journal of Hematology in 2021.COA of Formula: C16H21Cl2N3O2 The following contents are mentioned in the article:

Hemolytic crisis due to Covid-19 vaccination in a woman with cold agglutinin disease, the patient was treated with prednisone 20 mg daily with improvement of the hemolytic parameters and Hb level to baseline values. This study involved multiple reactions and reactants, such as 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7COA of Formula: C16H21Cl2N3O2).

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.COA of Formula: C16H21Cl2N3O2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Convenient syntheses of bulky group containing imidazolium ionic liquids was written by Kumar, Neeraj;Jain, Rahul. And the article was included in Journal of Heterocyclic Chemistry in 2012.Product Details of 157310-73-1 The following contents are mentioned in the article:

The authors report syntheses of imidazolium based ionic liquids containing bulky groups. The bulky groups were introduced at N-1, C-2, and N-3 positions of the imidazole ring using convenient methodologies. This study involved multiple reactions and reactants, such as 1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1Product Details of 157310-73-1).

1,2-Dimethyl-3-propyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 157310-73-1) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Product Details of 157310-73-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

An efficient synthesis of bis(indolyl)methanes catalyzed by recycled acidic ionic liquid was written by Gu, Da-Gong;Ji, Shun-Jun;Jiang, Zhao-Qin;Zhou, Min-Feng;Loh, Teck-Peng. And the article was included in Synlett in 2005.Product Details of 478935-29-4 The following contents are mentioned in the article:

Green, mild and efficient electrophilic substitution reactions of indoles with various aldehydes were carried out using task-specific ionic liquids to afford bis(indolyl)methanes in excellent yields. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Product Details of 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Product Details of 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Bis(arylimidazole) Iridium Picolinate Emitters and Preferential Dipole Orientation in Films was written by Huckaba, Aron J.;Senes, Alessia;Aghazada, Sadig;Babaei, Azin;Meskers, Stefan C. J.;Zimmermann, Iwan;Schouwink, Pascal;Gasilova, Natalia;Janssen, Rene A. J.;Bolink, Henk J.;Nazeeruddin, Mohammad Khaja. And the article was included in ACS Omega in 2018.Product Details of 914306-50-6 The following contents are mentioned in the article:

The straightforward synthesis and photophys. properties of a new series of heteroleptic iridium(III) bis(2-arylimidazole) picolinate complexes are reported. Each complex has been characterized by NMR, UV-vis, cyclic voltammetry, and photoluminescent angle dependency, and the emissive properties of each are described. The preferred orientation of transition dipoles in emitter/host thin films indicated more preferred orientation than homoleptic complex Ir(ppy)₃. This study involved multiple reactions and reactants, such as 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6Product Details of 914306-50-6).

1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Product Details of 914306-50-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Chitosan/ionic liquid forms a renewable and reusable catalyst system used for the synthesis of highly functionalized spiro derivatives was written by Rai, Pratibha;Srivastava, Madhulika;Singh, Jaya;Singh, Jagdamba. And the article was included in New Journal of Chemistry in 2014.HPLC of Formula: 478935-29-4 The following contents are mentioned in the article:

Chitosan, a reusable heterogeneous catalyst, can be combined with an ionic liquid as a green solvent to generate a highly efficient catalyst system for densely functionalized and diversified target mol. The reaction is completed with a good to excellent yield. This procedure demonstrates an eco-friendly catalyst system and eliminates the use of toxic transition metal catalysts, bases and volatile organic solvents, which adversely affect the environment and human beings. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4HPLC of Formula: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.HPLC of Formula: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A direct method for the substitution of imidazo[1,5-a]pyridines at position 5 was written by Blatcher, Philip;Middlemiss, David. And the article was included in Tetrahedron Letters in 1980.Synthetic Route of C10H10N2O2 The following contents are mentioned in the article:

Lithiation of 3-ethylthioimidazo[1,5-a]pyridine (I; R = SEt, R¹ = H) (II) occurred at C-5. Quenching of this anion followed by desulfurization gave 5-substituted imidazo[1,5-a]pyridines. E.g. II reacted with BuLi and PhCHO giving 71% I [R = SEt, R¹ = CH(OH)Ph] which on treatment with Raney Ni gave 65% I [R = H, R¹ = CH(OH)Ph]. This study involved multiple reactions and reactants, such as Ethyl imidazo[1,5-a]pyridine-5-carboxylate (cas: 76292-67-6Synthetic Route of C10H10N2O2).

Ethyl imidazo[1,5-a]pyridine-5-carboxylate (cas: 76292-67-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Synthetic Route of C10H10N2O2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Selective and efficient oxidation of sulfides to sulfoxides using ceric ammonium nitrate (CAN)/Bronsted acidic ionic liquid was written by Hajipour, Abdol R.;Khazdooz, Leila;Ruoho, Arnold E.. And the article was included in Phosphorus, Sulfur and Silicon and the Related Elements in 2009.COA of Formula: C10H20N2O4S The following contents are mentioned in the article:

A selective and efficient procedure for the oxidation of sulfides to the corresponding sulfoxides was reported using ceric ammonium nitrate in the presence of methylimidazolium hydrogen sulfate as Bronsted acidic ionic liquid ([Hmim]HSO₄) as the solvent under mild conditions. The use of nontoxic and inexpensive materials, straightforward procedure, short reaction times, and good yields of the products are the major advantages of this method. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4COA of Formula: C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.COA of Formula: C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of N-(α-Alkoxyalkyl)benzotriazoles catalyzed by acidic ionic liquid at room temperature was written by Wang, Hong-Xia;Ji, Shun-Jun;Gu, Da-Gong. And the article was included in Chinese Journal of Chemistry in 2007.Recommanded Product: 478935-29-4 The following contents are mentioned in the article:

N-(α-Alkoxyalkyl)benzotriazoles were synthesized with ≤99% yield via the condensation of benzotriazole with various aldehydes and alcs. catalyzed by acidic ionic liquid [hmim]HSO₄ (hmim = 1-hexyl-3-methylimidazolium) at room temperature This novel method was effective when (EtO)₃CH was utilized instead of alcs. Moreover, acidic ionic liquid could be reused easily with no significant degradation of its catalytic activity. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Recommanded Product: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Recommanded Product: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem