Category: imidazoles-derivatives

Study on the alkylation of isobutane/butene in acidic ionic liquids was written by Liu, Ying;Hu, Rui-sheng;Liu, Gui-li;Xu, Chun-ming. And the article was included in Fenzi Cuihua in 2010.SDS of cas: 478935-29-4 The following contents are mentioned in the article:

The catalytic performance of acidic ionic liquids on the isobutane/butene alkylation was investigated. The acidic strength of ionic liquids has been improved by modified cation, anion and liquid acid. The amount of TMP in the [MBSIM]OTf alkylate can reach 69.8%. The reaction system can be used for 8 times without significant decrease in catalytic performance. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4SDS of cas: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).SDS of cas: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A novel preparation of thiazolo[5,4-c]pyridines and the synthesis of some imidazo[4,5-c]pyridines and oxazolo[4,5-c]pyridines was written by Katner, Allen S.;Brown, Raymond F.. And the article was included in Journal of Heterocyclic Chemistry in 1990.SDS of cas: 52538-09-7 The following contents are mentioned in the article:

Diethoxymethyl acetate was used to cyclize o-disubstituted aminopyridines to oxazolo [4,5-c]pyridines and imidazo[4,5-c]pyridines. All the possible imidazole-methylated imidazo[4,5-c]pyridines were prepared A novel synthesis of 2-substituted thiazolo[5,4-c]pyridines and 4-amino-3-pyridinethiol was discovered. This study involved multiple reactions and reactants, such as 2,3-Dimethyl-3H-imidazo[4,5-c]pyridine (cas: 52538-09-7SDS of cas: 52538-09-7).

2,3-Dimethyl-3H-imidazo[4,5-c]pyridine (cas: 52538-09-7) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).SDS of cas: 52538-09-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Novel ionic liquid-mediated approach for the synthesis of tetracyclic[6,5,5,5]indole ring was written by Srivastava, Arjita;Siddiqui, Ibadur Rahman. And the article was included in Journal of Heterocyclic Chemistry in 2020.Formula: C10H20N2O4S The following contents are mentioned in the article:

A novel acidic ionic liquid-catalyzed protocol for the synthesis of diversely substituted tetracyclic indole core was devised. The application of ionic liquid provided this methodol. with various merits over conventional methods regarding reaction time, yield and ease of handling. Acidic ionic liquid was employed as a catalytic agent in this protocol. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Formula: C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Formula: C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by acidic ionic liquid was written by Ma, Jing-Jun;Zang, Xiao-Huan;Zhou, Xin;Wang, Chun;Li, Jing-Ci;Li, Qing. And the article was included in Indian Journal of Chemistry in 2007.Quality Control of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate The following contents are mentioned in the article:

3,4-Dihydropyrimidin-2(1H)-ones were synthesized via one-pot reaction of aromatic aldehydes, Et acetoacetate and urea or thiourea catalyzed by room temperature ionic liquid [hmim]HSO₄. It was observed that the proposed method is fast, efficient and environmentally benign. The reaction time is 15 ∼ 55 min with the yields between 82 ∼ 97 %. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Quality Control of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Quality Control of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Acidic ionic liquid-catalyzed highly efficient reaction of indoles to α,β-unsaturated ketones was written by Gu, Da-gong;Ji, Shun-jun;Wang, Hong-xia;Xu, Qiu-yan. And the article was included in Synthetic Communications in 2008.Recommanded Product: 478935-29-4 The following contents are mentioned in the article:

A novel method for the Michael reaction of indoles to α,β-unsaturated ketones catalyzed by acidic ionic liquid was reported. The authors obtained the corresponding products in excellent yields in the presence of [hmim]HSO₄. Development of this method resulted in a new protocol for the synthesis of β-indolylketones. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Recommanded Product: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Recommanded Product: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Bis(arylimidazole) Iridium Picolinate Emitters and Preferential Dipole Orientation in Films was written by Huckaba, Aron J.;Senes, Alessia;Aghazada, Sadig;Babaei, Azin;Meskers, Stefan C. J.;Zimmermann, Iwan;Schouwink, Pascal;Gasilova, Natalia;Janssen, Rene A. J.;Bolink, Henk J.;Nazeeruddin, Mohammad Khaja. And the article was included in ACS Omega in 2018.Product Details of 914306-50-6 The following contents are mentioned in the article:

The straightforward synthesis and photophys. properties of a new series of heteroleptic iridium(III) bis(2-arylimidazole) picolinate complexes are reported. Each complex has been characterized by NMR, UV-vis, cyclic voltammetry, and photoluminescent angle dependency, and the emissive properties of each are described. The preferred orientation of transition dipoles in emitter/host thin films indicated more preferred orientation than homoleptic complex Ir(ppy)₃. This study involved multiple reactions and reactants, such as 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6Product Details of 914306-50-6).

1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Product Details of 914306-50-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Chitosan/ionic liquid forms a renewable and reusable catalyst system used for the synthesis of highly functionalized spiro derivatives was written by Rai, Pratibha;Srivastava, Madhulika;Singh, Jaya;Singh, Jagdamba. And the article was included in New Journal of Chemistry in 2014.HPLC of Formula: 478935-29-4 The following contents are mentioned in the article:

Chitosan, a reusable heterogeneous catalyst, can be combined with an ionic liquid as a green solvent to generate a highly efficient catalyst system for densely functionalized and diversified target mol. The reaction is completed with a good to excellent yield. This procedure demonstrates an eco-friendly catalyst system and eliminates the use of toxic transition metal catalysts, bases and volatile organic solvents, which adversely affect the environment and human beings. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4HPLC of Formula: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.HPLC of Formula: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A direct method for the substitution of imidazo[1,5-a]pyridines at position 5 was written by Blatcher, Philip;Middlemiss, David. And the article was included in Tetrahedron Letters in 1980.Synthetic Route of C10H10N2O2 The following contents are mentioned in the article:

Lithiation of 3-ethylthioimidazo[1,5-a]pyridine (I; R = SEt, R¹ = H) (II) occurred at C-5. Quenching of this anion followed by desulfurization gave 5-substituted imidazo[1,5-a]pyridines. E.g. II reacted with BuLi and PhCHO giving 71% I [R = SEt, R¹ = CH(OH)Ph] which on treatment with Raney Ni gave 65% I [R = H, R¹ = CH(OH)Ph]. This study involved multiple reactions and reactants, such as Ethyl imidazo[1,5-a]pyridine-5-carboxylate (cas: 76292-67-6Synthetic Route of C10H10N2O2).

Ethyl imidazo[1,5-a]pyridine-5-carboxylate (cas: 76292-67-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Synthetic Route of C10H10N2O2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Selective and efficient oxidation of sulfides to sulfoxides using ceric ammonium nitrate (CAN)/Bronsted acidic ionic liquid was written by Hajipour, Abdol R.;Khazdooz, Leila;Ruoho, Arnold E.. And the article was included in Phosphorus, Sulfur and Silicon and the Related Elements in 2009.COA of Formula: C10H20N2O4S The following contents are mentioned in the article:

A selective and efficient procedure for the oxidation of sulfides to the corresponding sulfoxides was reported using ceric ammonium nitrate in the presence of methylimidazolium hydrogen sulfate as Bronsted acidic ionic liquid ([Hmim]HSO₄) as the solvent under mild conditions. The use of nontoxic and inexpensive materials, straightforward procedure, short reaction times, and good yields of the products are the major advantages of this method. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4COA of Formula: C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.COA of Formula: C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of N-(α-Alkoxyalkyl)benzotriazoles catalyzed by acidic ionic liquid at room temperature was written by Wang, Hong-Xia;Ji, Shun-Jun;Gu, Da-Gong. And the article was included in Chinese Journal of Chemistry in 2007.Recommanded Product: 478935-29-4 The following contents are mentioned in the article:

N-(α-Alkoxyalkyl)benzotriazoles were synthesized with ≤99% yield via the condensation of benzotriazole with various aldehydes and alcs. catalyzed by acidic ionic liquid [hmim]HSO₄ (hmim = 1-hexyl-3-methylimidazolium) at room temperature This novel method was effective when (EtO)₃CH was utilized instead of alcs. Moreover, acidic ionic liquid could be reused easily with no significant degradation of its catalytic activity. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Recommanded Product: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Recommanded Product: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem