Imidazoles-derivatives

Synergy of ionic liquid and confinement in the design of supported palladium catalyst for efficient selective hydrogenation of acetylene was written by Wang, Qingtao;Xu, Yiqi;Zhou, Jing;Xu, Longyu;Yu, Lu;Jiang, Dahao;Lu, Chunshan;Pan, Zhiyan;Zhang, Qunfeng;Li, Xiaonian. And the article was included in Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) in 2021.Related Products of 79917-89-8 This article mentions the following:

We present here a novel fabrication of highly effective supported Pd catalysts (Pd@S-1@IL) derived from Pd@S-1 core-shell material coated with ionic liquids (ILs), [Prmim][Cl], for the selective hydrogenation of acetylene. Catalytic testing on Pd@S-1@IL catalyst illustrated a remarkable selectivity towards semi-hydrogenation (over 90% for ethylene, irresp. of conversion level). Moreover, no indications of deactivation were observed after 800 h on stream even under relatively severe conditions. Detailed characterization indicated that the selectivity enhancement was ascribed to the filter effect along with electronic effect on the adsorption/desorption processes arising from the ionic liquids layer. The stability, which has ranked the top reported values over advanced Pd-based catalysts, is attributed to the confinement effect of Pd NPs within the supports thus restricting the migration of metals. The fabrication of core-shell architecture combined with the advantages of ionic liquid layer offers a promising guideline for efficient catalytic transfer of chem. resource. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Related Products of 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Related Products of 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Effectively catalytic hydrolysis of cellulose to glucose in the presence of pyrrolidonium-based acidic ionic liquids was written by Feng, Jianping;Liu, Min;Jia, Songyan;Gong, Yanyan;Song, Chunshan;Guo, Xinwen. And the article was included in Shiyou Xuebao, Shiyou Jiagong in 2012.Name: 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

A series of acidic ionic liquids (methylimidazolium-based acidic ionic liquids and pyrrolidonium-based acidic ionic liquids) were synthesized and characterized. The cellulose hydrolysis into glucose, in which ionic liquid 1-butyl-3-methylimidazolium ([Bmim]Cl) was used as the solvent, in the presence of the synthesized acidic ionic liquids was studied systematically. The influences of water content, procedure of adding water, kinds of catalyst, catalyst dosage, reaction temperature and reaction time on the conversion of cellulose and yield of glucose were investigated. It was shown that pyrrolidonium-based acidic ionic liquids were better in catalyzing the hydrolysis of cellulose into glucose than methylimidazolium-based acidic ionic liquids Under the optimized reaction conditions, which were the reaction temperature of 110掳C, n(catalyst): (glucose unit in cellulose): n(H₂O) = 1:3:210, [Hnmp]CH₃SO₃ as catalyst, with the water addition of once per 10 min in 40 min, and the reaction time of 2 h, the glucose yield of cellulose hydrolysis was 68%. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Name: 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Name: 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Quantum chemical study on nitroimidazole, polynitroimidazole and their methyl derivatives was written by Su, Xinfang;Cheng, Xinlu;Meng, Chuanmin;Yuan, Xiaoli. And the article was included in Journal of Hazardous Materials in 2009.Recommanded Product: 3034-41-1 This article mentions the following:

The insensitive explosive candidates, nitroimidazoles, polynitroimidazoles and their Me derivatives, are studied using d. functional theory (DFT). The homolytic bond dissociation energies (BDEs) corresponding to -NO₂ group removal from C or N site on imidazole ring were calculated at B3P86/6-311G** level, and the weakest bond has been determined A correlation is developed between impact sensitivity h₅₀ and the ratio (BDE/E) of the weakest bond BDE to the total energy E, and we extrapolate this relation to predict the impact sensitivities for compounds where experiments are not available. It is found that most of the title compounds are insensitive towards impact stimuli with their h₅₀ >60.0 cm. Heats of formation (HOFs) for the 21 title compounds at 298 K in gas are also determined both at B3LYP/6-311G** and B3P86/6-311G** levels using isodesmic work reactions. The calculated BDEs and HOFs consistently indicate that C-nitro-substituted imidazole is more stable than the corresponding N-substituted one, and the introduction of Me on C increases the stability whereas the Me attached to N atom decreases the stability. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Recommanded Product: 3034-41-1).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Recommanded Product: 3034-41-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Chemiluminescent intensities from substituted lophines was written by Philbrook, G. E.;Maxwell, M. A.. And the article was included in Tetrahedron Letters in 1964.Formula: C22H16N2O2 This article mentions the following:

Chemiluminescent intensities of 14 lophine derivatives, substituted in the 3 and (or) 4 position(s) of the 2-phenyl group, were determined in 7:3 Me₂SO-H₂O solution, N in NaOH. O was passed through the solution continuously. The intensity of emission passed through a maximum (I_maximum) after 1-2 min. and then declined. A Hammett plot of I_maximum/I₀ against 蟽 values was reported, where I₀ is the intensity maximum for lophine (I). The observed slope, -1.96 卤 0.06, compares with a value of -1.16 卤 0.06 obtained when similar plots were constructed with 蟽⁺ values (Brown and Okamoto, CA 53, 9120f). The emission intensity was a linear function of concentration for I, and the 4-carboxy, 4-MeO, 3,4-dimethoxy, and 4-Cl derivatives over the concentration range 3 脳 10^-3 to 3 脳 10^-5 M. The chemiluminescent maximum for all the compounds, except the nitro derivative, fell at 5300 A. It appeared that the chemiluminescent processes in all cases examined yield the same mol. fragment. Probably the substituent present in the original derivative was not present in this fragment. In the experiment, the researchers used many compounds, for example, 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5Formula: C22H16N2O2).

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Formula: C22H16N2O2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Luminescent Eu^III Complexes Immobilized on a Vermiculite Clay Surface was written by Silva, Haryane R. M.;Fonseca, Maria G.;Espinola, Jose Geraldo P.;Brito, Hermi F.;Faustino, Wagner M.;Teotonio, Ercules E. S.. And the article was included in European Journal of Inorganic Chemistry in 2014.Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

Vermiculite clays were leached with HNO₃ and functionalized with (3-chloropropyl)trimethoxysilane. The resulting materials were modified with the methylimidazolium (MID) group to yield cationic surfaces. These materials were characterized by IR spectroscopy, elemental analyses, and sp. surface area. Tetrakis(尾-diketonate)europate(III) complexes, [EuL₄]^– [L = dibenzoylmethane (DBM) and thenoyltrifluoroacetone (TTA)], were immobilized on the vermiculite surface containing the imidazolium cation to yield hybrid surfaces named Vx-MID-EuL₄ (x = 0, 1, and 2), in which x represents the nitric acid concentration in mol L^-1 that was used in the leaching process. The highest luminescence intensities of the intraconfigurational-4f ⁵D₀鈫?sup>7FJ transitions (for which J = 0, 1, 2, 3, and 4) arising from [EuL₄]^– complexes were presented by the hybrid materials containing the amount of imidazolium cation, which depend on the leaching process. The excitation and emission spectra suggested an efficient intramol. energy-transfer process from ligand-to-Eu³⁺ ion in the supported materials. The photoluminescent properties of the hybrid materials were studied based on the emission quantum efficiency (畏), exptl. intensity parameters 惟₂ and 惟₄, and Einstein’s emission coefficient (A_0J). The values of these parameters for the V₂-MID-EuL₄ surface are close to those assigned to the [EuL₄]^– isolated complexes, which indicates that hybrid vermiculite materials are promising red phosphors. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of halogen derivatives of N-methylimidazole was written by El Borai, M.;Moustafa, A. H.;Anwar, M.;Abdel Hay, F. I.. And the article was included in Polish Journal of Chemistry in 1981.Recommanded Product: 4-Bromo-1-methylimidazole This article mentions the following:

1-Methylimidazole (I) was converted to 2-halo-, 2,5-dihalo-, 5-halo-, 2,4-dihalo-, 4,5-dihalo-, 4-halo-, and 2,4,5-trihalo-1-methylimidazoles. I was treated with BuLi and Br₂ to give 2-bromo-1-methylimidazole. The reaction of I with N-bromosuccinimide gave 5-bromo-1-methylimidazole. I reacted with iodine and HIO₃ to give 4,5-diiodo-1-methylimidazole. In the experiment, the researchers used many compounds, for example, 4-Bromo-1-methylimidazole (cas: 25676-75-9Recommanded Product: 4-Bromo-1-methylimidazole).

4-Bromo-1-methylimidazole (cas: 25676-75-9) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Recommanded Product: 4-Bromo-1-methylimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Insights into the interplay between molecular structure and diffusional motion in 1-alkyl-3-methylimidazolium ionic liquids: a combined PFG NMR and X-ray scattering study was written by Martinelli, A.;Marechal, M.;Oestlund, A.;Cambedouzou, J.. And the article was included in Physical Chemistry Chemical Physics in 2013.Category: imidazoles-derivatives This article mentions the following:

We report on how the local structure and the diffusional motion change upon increasing the alkyl chain length in 1-alkyl-3-methylimidazolium cation ionic liquids This study has been performed by combining pulsed field gradient (PFG) NMR spectroscopy and small angle X-ray scattering (SAXS) experiments The cationic side chain length varies from Et (n = 2) to hexadodecyl (n = 16), while the anion is always bis(trifluoromethanesulfonyl)imide (TFSI). We find that the self-diffusivity of the individual ionic species is correlated to the local structure in the corresponding ionic liquid, namely the nano-segregation into polar and non-polar domains. In agreement with previous results, we observe that for relatively short alkyl chains the cations diffuse faster than the anions; however we also note that this difference becomes less evident for longer alkyl chains and a cross-over is identified at n 鈮?8 with the anions diffusing faster than the cations. Our results indicate that this controversial behavior can be rationalized in terms of different types of cation-cation and anion-anion orderings, as revealed by a detailed anal. of the correlation lengths and their dispersion curves obtained from SAXS data. We also discuss the validity of the Stokes-Einstein relation for these ionic liquids and the evolution of the extrapolated cationic radius that was found to depend non-strictly linearly on n, in agreement with the cation-cation correlation lengths. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Category: imidazoles-derivatives).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Quaternization of azido-N-heteroarenes with Meerwein reagent: A straightforward synthesis of 2-azido(benzo)imidazolium and related azido-N-heteroarenium tetrafluoroborates was written by Li, Yan;Wan, Ting-Biao;Guo, Bin;Qi, Xiao-Wen;Zhu, Chifan;Shen, Mei-Hua;Xu, Hua-Dong. And the article was included in Tetrahedron Letters in 2022.Category: imidazoles-derivatives This article mentions the following:

The 2-azido(benzo)imidazolium salts e.g., I have been made through quaternization of 2-Azido(benzo)imidazoles e.g., II with Meerwein reagent at ambient conditions. This one-pot protocol is also applicable to 4 or 3-azidopyridines e.g., III and appropriate azido(iso)quinolines e.g., IV to prepare correlative azido-N-heteroarenium salts e.g., I. When compared with their precursors, improved diazotransfer reactivity was observed for several representative azido-N-heteroarenium salts e.g., I in reaction with di-Et malonate. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Category: imidazoles-derivatives).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Dynamic conformational and exchange processes in 2-(4′-pyridyl)benzazoles was written by Marzin, Claude;Peek, Michael E.;Elguero, Jose;Figeys, Hubert P.;Defay, Nicole. And the article was included in Heterocycles in 1977.COA of Formula: C9H8N2O This article mentions the following:

The rotational barrier about the C-C bond linking the heterocyclic ring systems in I (X = NH, NMe, NPh, O, S; Q = CH, N; R = Me, H), II, and III (R = H, Me; X = NH, NMe, NPh, O, S) were determined by 1H NMR. The H-exchange reaction in I (Q = CH, X = NH, R = H, Me) was slow enough to be observed in both 13C and 1H NMR as peak broadenings. The conformations of the heterocyclic ring systems are discussed. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4COA of Formula: C9H8N2O).

1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).COA of Formula: C9H8N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Manganese-Catalyzed Hydroborations with Broad Scope was written by Ghosh, Pradip;Jacobi von Wangelin, Axel. And the article was included in Angewandte Chemie, International Edition in 2021.Recommanded Product: 1-Methylbenzimidazole This article mentions the following:

Reductive transformations of easily available oxidized matter are at the heart of synthetic manipulation and chem. valorization. The applications of catalytic hydrofunctionalization benefit from the use of liquid reducing agents and operationally facile setups. Metal-catalyzed hydroborations provide a highly prolific platform for reductive valorizations of stable C:X electrophiles. Here, the authors report an especially facile, broad-scope reduction of various functions including carbonyls, carboxylates, pyridines, carbodiimides, and carbonates under very mild conditions with the inexpensive pre-catalyst Mn(hmds)₂. The reaction could be successfully applied to depolymerizations In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Recommanded Product: 1-Methylbenzimidazole).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Recommanded Product: 1-Methylbenzimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem