Imidazoles-derivatives

Ganesan, Ramakrishnan published the artcilePhotoactive Diazoketo-Functionalized Self-Assembled Monolayer for Biomolecular Patterning, Category: imidazoles-derivatives, the publication is Langmuir (2009), 25(16), 8888-8893, database is CAplus and MEDLINE.

A diazoketo-functionalized alkoxysilane compound was synthesized, and its self-assembled monolayer (SAM) formation was studied on glass and silicon substrates. IR spectroscopy was employed to follow the photoreaction in this system, which proved that carboxylic groups were generated from diazoketo groups in the surface of the substrate. Photopatterning of biotin/streptavidin on the diazoketo-functionalized SAM shows the potential of this novel platform for biomol. patterning.

Langmuir published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, Category: imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Kwon, Dong Yuel published the artcileTheoretical study of imidazole derivatives for blue thermally activated delayed fluorescence emitter, HPLC of Formula: 2622-67-5, the publication is Journal of Nanoscience and Nanotechnology (2016), 16(10), 11014-11017, database is CAplus.

Four novel thermally activated delayed fluorescence (TADF) materials with phenoxazine (PXZ) and 9,10-dihydro-9,9-dimethylacridine (ACR) as electron donors and 1,2-diphenyl-1H-phenanthro[9,10- d]imidazole (PI), and 1,2-diphenyH H-benzo[d]imidazole (Bl) as electron acceptors (PXZ-PI, ACR- Pl, PXZ-BI, ACR-BI) were designed and theor. investigated for blue OLED emitter. Using DFT and TDDFT calculations, we gained the electron distribution of HOMO and LUMO and the energy of the lowest singlet (S1) and the lowest triplet (T1) excited states. All of the materials have a small spatial overlap between HOMO and ã-UMÖ because of the relatively large dihedral angle between the Ph ring and the acceptor moiety. In terms of the energy difference (ΔEST) between the (S1) state and the T1, state, PXZ-PI, PXZ-BI, and ACR-BI showed the small ΔEST. However, ACR-PI showed the large ΔEST. Among the TADF materials, we showed that ACR-BI would have the best TADF properties in terms of small ΔEST and blue LED emitters.

Journal of Nanoscience and Nanotechnology published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, HPLC of Formula: 2622-67-5.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Jung, Chan-Hee published the artcileA study on the immobilization of biomolecules on poly(acrylic acid)-grafted MWCNTs prepared by radiation-induced graft polymerization, HPLC of Formula: 359860-27-8, the publication is Polymer (Korea) (2010), 34(2), 150-153, database is CAplus.

In this research. biomol.-immobilized multi-walled carbon nanotubes (MWCNTs) were prepared by using radiation-induced graft polymerization For the immobilization of biomols., the surface of MWNCTs was functionalized by radiation-induced graft polymerization of acrylic acid. Based on the results of TGA and Raman spectroscopy it was found that acrylic acid was effectively graft-polymerized on the MWCNTs. Biomols. such as DNA and proteins were immobilized onto the resultant poly(acrylic acid)-grafted MWCNTs. The results of the XPS and fluorescence microscopy confirmed that the biomols. were successfully immobilized on the poly(acrylic acid)-grafted MWCNTs.

Polymer (Korea) published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, HPLC of Formula: 359860-27-8.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Jeong, Seung Pyo published the artcileBinding behaviors of protein on spatially controlled poly[oligo(ethylene glycol) methacrylate] brushes grafted from mixed self-assembled monolayers on gold, Category: imidazoles-derivatives, the publication is Chemical Communications (Cambridge, United Kingdom) (2014), 50(40), 5291-5293, database is CAplus and MEDLINE.

Binding behaviors of streptavidin were studied with different lateral packing densities of biotin-functionalized, nonbiofouling pOEGMA brushes, synthesized by surface-initiated polymerization from mixed SAMs with different mole fractions of the polymerization initiator on Au surfaces.

Chemical Communications (Cambridge, United Kingdom) published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, Category: imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Chi, Young Shik published the artcileAsymmetrically functionalized, four-armed, poly(ethylene glycol) compounds for construction of chemically functionalizable non-biofouling surfaces, Synthetic Route of 359860-27-8, the publication is Chemistry – An Asian Journal (2009), 4(1), 135-142, database is CAplus and MEDLINE.

Asym. functionalized, four-armed, Tween20 derivatives that formed stable monomol. films on solid substrates were designed and synthesized. Thiol-modified Tween20 was used for forming self-assembled monolayers (SAMs) on gold, and maleimide-modified Tween20 was introduced onto SiO₂ surfaces with SAMs of (3-mercaptopropyl)trimethoxysilane through Michael addition These structurally modified Tween20 compounds gave the original characteristics of Tween20, non-biofouling (from ethylene glycol groups) and functionalizable (from OH groups) properties, to each substrate. The non-biofouling properties of the Tween20-coated gold and SiO₂ surfaces were investigated by surface plasmon resonance spectroscopy and ellipsometry, and these surfaces showed strong resistance against nonspecific adsorption of proteins. In addition, the biospecific binding of streptavidin was achieved after coupling of (+)-biotinyl-3,6,9-trioxaundecanediamine onto the non-biofouling surfaces through amide-bond formation.

Chemistry – An Asian Journal published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, Synthetic Route of 359860-27-8.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Estenne, Genevieve published the artcileAn efficient synthesis of chlorinated imidazoles through tert-butyldimethylsiloxy derivatives, COA of Formula: C8H13ClN2O, the publication is Journal of Heterocyclic Chemistry (1994), 31(5), 1121-3, database is CAplus.

The protection of 2-substituted imidazole-5-methanol derivatives by a tert-butyldimethylsilyl group allowed the chlorination of the heterocycle in position 4 with good yield whereas direct chlorination of the imidazole alc. was unsuccessful. The preparation of 4-chloroimidazole derivative I was described.

Journal of Heterocyclic Chemistry published new progress about 79047-41-9. 79047-41-9 belongs to imidazoles-derivatives, auxiliary class Imidazole,Chloride,Alcohol, name is (2-Butyl-4-chloro-1H-imidazol-5-yl)methanol, and the molecular formula is C8H13ClN2O, COA of Formula: C8H13ClN2O.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Yahya, M. S. published the artcileDominance of hydrophobic attraction in attachment of microbubbles and Graphene oxide (GO), Synthetic Route of 79917-90-1, the publication is Chemical Engineering Science (2022), 117033, database is CAplus.

This paper presents the synthesis of GO-coated microbubbles which would be useful for environmental remediation and enhanced heat transfer applications. The mechanism of microbubble-GO attachment including electrostatic interactions, hydrophobic attraction, contact angle and Gibb’s free energy were determined Preliminary experiments indicated that water alone is not favorable, which thus necessitated the use of a bridging surfactant. The optimum attachment between microbubbles and GO occurred at the GO’s isoelec. point (IEP) in the ionic liquid as surfactant (IL), in which the IL concentration allowed GO to achieve maximum hydrophobicity. Therefore, it is inferred that hydrophobic attraction is the dominant force for microbubble-GO attachment with minor contributions from electrostatic interactions. Further studies showed that the longest carbon chain length IL, i.e. 1-Dodecyl-3-methylimidazolium chloride ([C₁₂mim]Cl) produced the most conducive environment for microbubble-GO attachment at its IEP concentration of 350 ppm.

Chemical Engineering Science published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C10H15NS, Synthetic Route of 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Nguyen, Khac Minh Huy published the artcileA Bioinspired Catalytic Aerobic Oxidative C-H Functionalization of Primary Aliphatic Amines: Synthesis of 1,2-Disubstituted Benzimidazoles, Safety of 1,2-Diphenyl-1H-benzo[d]imidazole, the publication is Chemistry – A European Journal (2015), 21(36), 12606-12610, database is CAplus and MEDLINE.

Aerobic oxidative C-H functionalization of primary amines has been accomplished with a biomimetic cooperative catalytic system to furnish 1,2-disubstituted benzimidazoles I [R¹ = Me, C₆H₅, 4-ClC₆H₄; R² = cyclopropyl, n-pentyl, Ph, etc.] under ambient air. This one-pot protocol has many advantages like mild reaction conditions, low catalyst loading, atom-economical process, simple work-up and convenient strategy to functionalize non-activated primary amines also.

Chemistry – A European Journal published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Safety of 1,2-Diphenyl-1H-benzo[d]imidazole.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Nguyen, Khac Minh Huy published the artcileCatalytic Oxidative Coupling of Primary Amines under Air: A Flexible Route to Benzimidazole Derivatives, Product Details of C19H14N2, the publication is European Journal of Organic Chemistry (2016), 2016(5), 1025-1032, database is CAplus.

Benzimidazoles are of fundamental importance in chem. and biol., and the development of efficient, environmentally benign methods for their preparation remains a key challenge for organic chemists. In a biomimetic approach inspired by copper amine oxidases, we disclose herein the scope and factors influencing the success of the cooperative action of CuBr₂ as electron-transfer mediator and a topaquinone-like substrate-selective catalyst in the oxidative cyclocondensation of primary amines with o-aminoanilines. This one-pot atom-economic multistep process, which works under green conditions with ambient air as the terminal oxidant, low loadings of catalyst, and equimolar amounts of com. available amine substrates, is particularly suitable for the preparation of 1,2-disubstituted benzimidazoles, e. g., I. Furthermore, it allows the functionalization of nonactivated primary aliphatic amines, which are known to be challenging substrates for non-enzymic catalytic aerobic systems.

European Journal of Organic Chemistry published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Product Details of C19H14N2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Blom, Elisabeth published the artcile⁶⁸Ga-Labeling of Biotin Analogues and their Characterization, COA of Formula: C18H34N4O5S, the publication is Bioconjugate Chemistry (2009), 20(6), 1146-1151, database is CAplus and MEDLINE.

Biotin- and ⁶⁸Ga-based tracers have been suggested as tools that could be used to monitor the survival of avidin-coated islets of Langerhans isolated from pancreas and used in transplantation, i.e., to liver. Three biotin analogs with various alkyl and poly(ethylene glycol) (PEG) chains coupled to DOTA were synthesized and labeled with ⁶⁸Ga. The ⁶⁸Ga labeling was studied at room temperature as well as elevated temperature using either conventional or microwave heating. Radioactivity incorporation reached 95% within 5 and 2 min using the, resp., conventional and microwave heating modes. The specific activity of the tracers was improved by preconcentration and purification of the generator eluate. The binding of the labeled and nonlabeled conjugates to avidin in solution was compared to the binding of native biotin. All compounds maintained good affinity for avidin, though introducing the linkers and chelator, especially the PEG-groups, somewhat decreased the binding affinity. The extent of binding of the labeled compounds to avidin was 54-91% after 5 min. Blocking experiments were performed confirming the specificity of the binding of biotin analogs to avidin. The stability of the three labeled compounds in human serum was studied. The stability of the biotin analog 8 (65% within 30 min) and avidin-biotin complex (80% within 120 min) might be sufficient for the monitoring of the islets of Langerhans. The tracers will be evaluated in in vitro experiments of avidin-coated islets of Langerhans and in transplantation models in vivo.

Bioconjugate Chemistry published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, COA of Formula: C18H34N4O5S.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem