Tag: 0-100

《Synthesis, thermal stability, vibrational spectra and conformational studies of novel dicationic meta-xylyl linked bis-1-methylimidazolium ionic liquids》 was written by Boumediene, Mostefa; Haddad, Boumediene; Paolone, Annalisa; Drai, Mokhtar; Villemin, Didier; Rahmouni, Mustapha; Bresson, Serge; Abbas, Ouissam. Formula: C4H6N2This research focused onxylyl methylimidazolium ionic liquid thermal stability IR Raman spectra. The article conveys some information:

In recent years, dicationic ionic liquids have been subject of a strongly growing research effort for their interesting and important properties that suggest them to be potential candidate for many applications. Therefore, the knowledge about the synthesis, thermal stability, vibrational spectra and conformational behavior of these compounds is an important subject of study. The objective of the work presented in this paper is to investigate the influence of the substituent relative meta-position of dicationic ionic liquids (ILs), namely meta-xylyl linked bis-1-methylimidazolium ILs, on thermal stability, vibrational spectra and conformational studies. The obtained dicationic ILs were characterized by 1H NMR, 13C NMR, 19F NMR, 31P NMR and FT-IR spectroscopy. Also, their thermal properties were determined and compared. The thermal behavior confirmed that [m-C6H4(CH2ImMe)2+] dicationic ILs containing [(CF3SO2)2N-]2 and [PF6-]2 are more stable that the dichloride [Cl-]2, and bis(tetrafluoroborate) [BF4-]2 dicationic ILs, and they show a good thermal stability up to 340 °C which makes them suitable for thermal application. In the next step, a computational study of the conformers of [m-C6H4(CH2ImMe)2+], by means of DFT calculations with the 6-31G** basis set and the B3LYP theory was performed. Addnl., vibrational spectroscopy studies were conducted by IR (FTIR) and Raman (FT-Raman) spectroscopy on the four dicationic ILs, differing for their anions. Finally a computational investigation of the interactions between anions and cation is presented. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazole(cas: 616-47-7Formula: C4H6N2)

1-Methyl-1H-imidazole(cas: 616-47-7) is used as a precursor for the synthesis of pyrrole-imidazole polyamides, ionic liquids such as 1-butyl-3-methylimidazolium hexafluorophosphate.Formula: C4H6N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Recommanded Product: 616-47-7In 2021 ,《Immunoinformatics and Pepscan strategies on the path of a peptide-based serological diagnosis of COVID19》 was published in Journal of Immunological Methods. The article was written by Lorenzo, Maria A.; Pachon, Diana; Maier, Alexandra; Bermudez, Henry; Losada, Sandra; Toledo, Marilyan; Pujol, Flor H.; Alarcon de Noya, Belkisyole; Noya, Oscar; Serrano, Maria Luisa. The article contains the following contents:

Several diagnostic tools have been developed for clin. and epidemiol. assays. RT-PCR and antigen detection tests are more useful for diagnosis of acute disease, while antibody tests allow the estimation of exposure in the population. Currently, there is an urgent need for the development of diagnostic tests for COVID-19 that can be used for large-scale epidemiol. sampling. Through a comprehensive strategy, potential 16 mer antigenic peptides suited for antibody-based SARS-CoV-2 diagnosis were identified. A systematic scan of the three structural proteins (S,N and M) and the non-structural proteins (ORFs) present in the SARS-CoV-2 virus was conducted through the combination of immunoinformatic methods, peptide SPOT synthesis and an immunoassay with cellulose-bound peptides (Pepscan). The Pepscan filter paper sheets with synthetic peptides were tested against pools of sera of COVID-19 patients. Antibody recognition showed a strong signal for peptides corresponding to the S, N and M proteins of SARS-CoV-2 virus, but not for the ORFs proteins. The peptides exhibiting higher signal intensity were found in the C-terminal region of the N protein. Several peptides of this region showed strong recognition with all three Igs in the pools of sera. The differential reactivity observed between the different Ig isotypes (IgA, IgM and IgG) within different regions of the S and N proteins, can be advantageous for ensuring accurate diagnosis of all infected patients, with different times of exposure to infection. Few peptides of the M protein showed antibody recognition and no recognition was observed for peptides of the ORFs proteins. The results came from multiple reactions, including the reaction of 1-Methyl-1H-imidazole(cas: 616-47-7Recommanded Product: 616-47-7)

1-Methyl-1H-imidazole(cas: 616-47-7) is used as a precursor for the synthesis of pyrrole-imidazole polyamides, ionic liquids such as 1-butyl-3-methylimidazolium hexafluorophosphate.Recommanded Product: 616-47-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Yang, Lixia; Han, Yuexia; Jiao, Zhen published an article in 2021. The article was titled 《Measurement and Correlation of Liquid-Liquid Equilibria of Water (1) + 1-Methylimidazole (2) + [Bmim][PF6] (3) Ternary Systems between 303.15 and 323.15 K》, and you may find the article in Journal of Chemical & Engineering Data.Computed Properties of C4H6N2 The information in the text is summarized as follows:

To obtain the basic data for the recovery of 1-methylimidazole from wastewater by extraction, the ternary liquid-liquid phase equilibrium data of the water (1) + 1-methylimidazole (2) + 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim][PF6]) (3) system were determined using an equilibrium autoclave at the temperatures of 303.15 to 323.15 K and 101.32 kPa. The solute distribution coefficient (D) and the selectivity (S) of the ternary system were calculated in accordance with the exptl. data. Their values were up to 1.39 and 41.17, resp., which showed that the ionic liquid can extract 1-methylimidazole effectively. The exptl. results showed that the temperature had a slight effect on the liquid-liquid equilibrium behavior. Meanwhile, the calculated results revealed that the selectivity coefficient decreased with the enhancing concentration of 1-methylimidazole in the ternary system and the increasing temperature In addition, the nonrandom two liquid (NRTL) model was used for correlation of the ternary systems. The root-mean-square deviation value of 0.0218 indicated that the calculated results using the model were in good agreement with the exptl. data and were reliable to apply to practice. The experimental part of the paper was very detailed, including the reaction process of 1-Methyl-1H-imidazole(cas: 616-47-7Computed Properties of C4H6N2)

1-Methyl-1H-imidazole(cas: 616-47-7) is used as a precursor for the synthesis of pyrrole-imidazole polyamides, ionic liquids such as 1-butyl-3-methylimidazolium hexafluorophosphate.Computed Properties of C4H6N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Kumar, Harsh; Kaur, Gagandeep published their research in Journal of Surfactants and Detergents in 2021. The article was titled 《Aggregation Behavior of Mixed Micellar System of Dodecyl Sulfate-Based Surface-Active Ionic Liquids and Anionic Surfactant in Aqueous Media》.Formula: C4H6N2 The article contains the following contents:

Mixed micellization behavior of dodecyl sulfate-based ionic liquids, i.e., 1-propyl-3-methylimidazolium dodecyl sulfate [C3mim][DS] and 1-hexyl-3-methylimidazolium dodecyl sulfate [C6mim][DS] with sodium dodecyl sulfate (SDS), is investigated at (298.15, 308.15, and 318.15) K in aqueous medium. For this, the conductometric measurements are carried out to evaluate the critical micelle concentrations (cmc), ideal critical micelle concentration (cmc*), degree of counterion dissociation (g), thermodn. parameters, micellar mole fraction of ionic liquids, and interaction parameter (β) of the mixed system based on the different proposed models given in the literature. Further surface tension measurements have been carried out to confirm the value of cmc obtained via a conductivity study for all the studied systems at 298.15 K. Other surface parameters, such as surface tension at cmc (γcmc), surface pressure ([n.7464]cmc), surface excess (Γmax), and min. area per mol. (Amin), have also been evaluated for both the systems. In the experimental materials used by the author, we found 1-Methyl-1H-imidazole(cas: 616-47-7Formula: C4H6N2)

1-Methyl-1H-imidazole(cas: 616-47-7) is actively involved in removing acid during the production of diethoxyphenylphosphine. It is used as an intermediate in organic synthesis.Formula: C4H6N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors》 were Deaton, David N.; Do, Young; Holt, Jason; Jeune, Michael R.; Kramer, H. Fritz; Larkin, Andrew L.; Orband-Miller, Lisa A.; Peckham, Gregory E.; Poole, Chuck; Price, Daniel J.; Schaller, Lee T.; Shen, Ying; Shewchuk, Lisa M.; Stewart, Eugene L.; Stuart, J. Darren; Thomson, Stephen A.; Ward, Paris; Wilson, Joseph W.; Xu, Tianshun; Guss, Jeffrey H.; Musetti, Caterina; Rendina, Alan R.; Affleck, Karen; Anders, David; Hancock, Ashley P.; Hobbs, Heather; Hodgson, Simon T.; Hutchinson, Jonathan; Leveridge, Melanie V.; Nicholls, Harry; Smith, Ian E. D.; Somers, Don O.; Sneddon, Helen F.; Uddin, Sorif; Cleasby, Anne; Mortenson, Paul N.; Richardson, Caroline; Saxty, Gordon. And the article was published in Bioorganic & Medicinal Chemistry in 2019. Application of 7720-39-0 The author mentioned the following in the article:

With the goal of discovering more selective anti-inflammatory drugs than COX inhibitors, to attenuate prostaglandin signaling, a fragment-based screen of hematopoietic prostaglandin D synthase was performed. The 76 crystallog. hits were sorted into similar groups, with the 3-cyano-quinoline 1a(I) (FP IC50 = 220,000 nM, LE = 0.43) being a potent member of the 6,6-fused heterocyclic cluster. Employing SAR insights gained from structural comparisons of other H-PGDS fragment binding mode clusters, the initial hit I was converted into the 70-fold more potent quinoline 1d(II) (IC50 = 3,100 nM, LE = 0.49). A systematic substitution of the amine moiety of II, utilizing structural information and array chem., with modifications to improve inhibitor stability, resulted in the identification of the 300-fold more active H-PGDS inhibitor tool compound 1bv(III) (IC50 = 9.9 nM, LE = 0.42). This selective inhibitor exhibited good murine pharmacokinetics, dose-dependently attenuated PGD2 production in a mast cell degranulation assay and should be suitable to further explore H-PGDS biol.1H-Imidazol-2-amine(cas: 7720-39-0Application of 7720-39-0) was used in this study.

1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Application of 7720-39-0

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Computed Properties of C3H5N3In 2020 ,《Proton-Induced Charge Transfer on Imidazole and 2-Aminoimidazole. Role of the Substituent and Influence of Stepwise Hydration》 appeared in Journal of Physical Chemistry A. The author of the article were Kerkeni, Boutheina; Bacchus-Montabonel, Marie-Christine. The article conveys some information:

The behavior of potential prebiotic species in space is of main concern in the chem. at the origin of life. Their reactivity or stability in spatial conditions, under strong UV radiations or ion bombardments, remains an open question and needs wide investigations. As protons are by far the most abundant ions in space, we focus presently on proton-induced collisions on imidazole and 2-aminoimidazole evidenced as important prebiotic RNA intermediates. Unconstrained full optimization of the structures was performed with B3LYP/cc-pVTZ model chem. The calculations were performed in a wide collision energy range in order to model various astrophys. environments, from eV in the interstellar medium, up to keV for solar winds or supernovae shock-wave protons. Such a study provides for the first time a theor. insight on the influence of the amino substituent on the proton-induced charge transfer. We evaluated the role of icy grain environments through a cluster approach modeling the effect of a stepwise microhydration on the process. Comparisons with oxygenated and sulfurated analogs address further qual. trends on the resp. stability or reactivity of such heterocycles which may be of tremendous interest in prebiotic chem. Charge transfer appears to be quite efficient for imidazole compounds and their sulfurated analog compared to the oxygenated heterocycle. The experimental process involved the reaction of 1H-Imidazol-2-amine(cas: 7720-39-0Computed Properties of C3H5N3)

1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Computed Properties of C3H5N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2022,Jacobi, Richard; Joerg, Florian; Steinhauser, Othmar; Schroeder, Christian published an article in Physical Chemistry Chemical Physics. The title of the article was 《Emulating proton transfer reactions in the pseudo-protic ionic liquid 1-methylimidazolium acetate》.Product Details of 616-47-7 The author mentioned the following in the article:

Proton transfer reactions can enhance conductivity in protic ionic liquids However, several proton reactions are possible in a multicomponent system of charged and neutral species, resulting in a complex reaction network. Probabilities and equilibrium concentrations of the involved species are modeled by the combination of reducible Markov chains and quantum-mech. calculations The experimental part of the paper was very detailed, including the reaction process of 1-Methyl-1H-imidazole(cas: 616-47-7Product Details of 616-47-7)

1-Methyl-1H-imidazole(cas: 616-47-7) is used as a precursor for the synthesis of pyrrole-imidazole polyamides, ionic liquids such as 1-butyl-3-methylimidazolium hexafluorophosphate.Product Details of 616-47-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Facile synthesis of nanostructured polyaniline in ionic liquids for high solubility and enhanced electrochemical properties》 were Li, Shihua; Yang, Chunying; Sarwar, Shatila; Nautiyal, Amit; Zhang, Pengfei; Du, Haishun; Liu, Na; Yin, Jialin; Deng, Kuilin; Zhang, Xinyu. And the article was published in Advanced Composites and Hybrid Materials in 2019. Recommanded Product: 616-47-7 The author mentioned the following in the article:

As one of the most investigated conducting polymers, polyaniline (PANI) is considered to be of practical use in many applications. In this study, two new ionic liquids, 1-methylimidazolium hydrogen sulfate ([Hmim]HSO4) and 1-methyl-3-n-butylimidazopersulfate ([C4mim]2S2O8), which were synthesized from 1-methylimidazole ([Hmim]), were used as solvent and dopant, oxidizer, resp., for in situ polymerization of aniline. Because of the application of the unique structure of ionic liquid, we obtained the ionic liquid-doped polyaniline (IL-PANI) with high solubility (25 mg mL-1 in DMSO (DMSO)). And by adjusting the ratio of [C4mim]2S2O8 to aniline monomer, the preferred PANI nanofibers could be controlled to form a three-dimensional porous structure. It was found that the ion/electron transport channels could be formed inside the 3D structure. Thus, the redox reactions could occur both at the surface and inside the PANI electrode. Electrochem. characterization showed that the fabricated PANI electrode exhibited a specific capacitance of 489 F g-1 at a c.d. of 0.5 A g-1. Also, the capacity retention rate reached up to 81% after 4000 cycles investigated at 2 A g-1. In addition, a high-energy d. of 80.2 Wh kg-1 was measured when [Hmim]HSO4 was used as an electrolyte. Thus, the present work suggested a new strategy for fabricating high-performance PANI electrode for supercapacitor applications. [Figure not available: see fulltext.]. The results came from multiple reactions, including the reaction of 1-Methyl-1H-imidazole(cas: 616-47-7Recommanded Product: 616-47-7)

1-Methyl-1H-imidazole(cas: 616-47-7) is used as a precursor for the synthesis of pyrrole-imidazole polyamides, ionic liquids such as 1-butyl-3-methylimidazolium hexafluorophosphate.Recommanded Product: 616-47-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Synthetic nanoparticles for selective hydrolysis of bacterial autoinducers in quorum sensing》 were Fa, Shixin; Zhao, Yan. And the article was published in Bioorganic & Medicinal Chemistry Letters in 2019. Synthetic Route of C3H5N3 The author mentioned the following in the article:

N-acyl homoserine lactones (AHLs) are signal mols. used by a large number of gram-neg. bacteria in quorum sensing and their hydrolysis is known to inhibit biofilm formation. Micellar imprinting of AHL-like templates with catalytic functional monomers yielded water-soluble nanoparticles with AHL-shaped active site and nearby catalytic groups. Either Lewis acidic zinc ions or nucleophilic pyridyl ligands could be introduced through this strategy, yielding artificial enzymes for the hydrolysis of AHLs in a substrate-selective fashion. In the experimental materials used by the author, we found 1H-Imidazol-2-amine(cas: 7720-39-0Synthetic Route of C3H5N3)

1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Synthetic Route of C3H5N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Inhibition Activity of Compounds and Bacteriophages against Flavobacterium psychrophilum Biofilms In Vitro》 were Papadopoulou, Anna; Dalsgaard, Inger; Wiklund, Tom. And the article was published in Journal of Aquatic Animal Health in 2019. Recommanded Product: 7720-39-0 The author mentioned the following in the article:

Flavobacterium psychrophilum produces biofilms under laboratory conditions, and it has been inconclusively suggested that F. psychrophilum biofilms can be a potential reservoir for transmission of the pathogen to a fish population under fish farming conditions. Therefore, there is a need for anti-biofilm compounds The main aim of this study was to determine the anti-biofilm properties of certain compounds and bacteriophages on F. psychrophilum biofilms under static conditions using a standard 96-well microtiter plate biofilm assay in vitro. Eight compounds (A-type proanthocyanidins, D-leucine, EDTA, emodin, fucoidan, L-alliin, parthenolide, and 2-aminoimidazole) at three sub-min. inhibitory concentrations (sub-MICs), four bacteriophages (Fpv-3, Fpv-9, Fpv-10, and Fpv-21), and a phage combination (Fpv-9 + Fpv-10) were tested for inhibition of biofilm formation and reduction of the biomass of mature biofilms formed by two smooth isolates (P7-9/10 and P1-10B/10) and two rough isolates (P7-9/2R/10 and P1-10B/2R/10) of F. psychrophilum. The crystal violet staining method was used to stain the biofilms. Most of the compounds at sub-MICs inhibited the biofilm formation of mainly smooth isolates, attaining up to 80% inhibition. Addnl., the same reduction trend was also observed for 2-aminoimidazole, emodin, parthenolide, and D-leucine on the biomass of mature biofilms in a concentration-dependent manner. The anti-biofilm properties of the compounds are believed to lie in their ability to disturb the cellular interactions during biofilm formation and probably to cause cell dispersal in already formed biofilms. Lytic bacteriophages efficiently inhibited biofilm formation of F. psychrophilum, while they partially reduced the biomass of mature biofilms. However, the phage combination (Fpv-9 + Fpv-10) showed a successful reduction in the biomass of F. psychrophilum mature biofilms. We conclude that inhibiting compounds together with bacteriophages may supplement the use of disinfectants against bacterial biofilms (e.g., F. psychrophilum biofilms), leading to a reduced occurrence of bacterial coldwater disease outbreaks at fish farms. The results came from multiple reactions, including the reaction of 1H-Imidazol-2-amine(cas: 7720-39-0Recommanded Product: 7720-39-0)

1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Recommanded Product: 7720-39-0

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem