Tag: 100-200

Tuan, Cao Manh; Tinh, Vo Dinh Cong; Kim, Dukjoon published an article in 2020, the title of the article was Anion exchange membranes prepared from quaternized polyepichlorohydrin cross-linked with 1-(3-aminopropyl)imidazole grafted poly(arylene ether ketone) for enhancement of toughness and conductivity.Recommanded Product: 5036-48-6 And the article contains the following content:

A novel anion exchange membrane was synthesized via crosslinking of the quaternized polyepichlorohydrin (QPECH) by 1-(3-aminopropyl) imidazole grafted poly(arylene ether ketone) (PAEK-API).While the QPECH provided an excellent ion conductive property, therigidrod-structured PAEK-API played a reinforcing role, along with providing the high conductivity associated with the pendant API group. The chem. structure of QPECH/PAEK-API membranes was identified by 1H nuclear magnetic resonace spectroscopy. A variety of membrane properties, such as anion conductivity, water uptake, length swelling percentage, and thermal, mech. and chem. stability, were investigated. The QPECH/PAEK-API1 membrane showed quite high hydroxide ion conductivity, from 0.022 S cm-1 (30°C) to 0.033 S cm-1 (80°C), and excellent mech. strength, associated with the low water uptake of less than 40%, even at 80°C. Such high conductivity at relatively low water uptake is attributed to the concentrated cationic groups, in a cross-linked structure, facilitating feasible ion transport. Further, the QPECH/PAEK-API membranes showed thermal stability up to 250°C, and chem. stability for 30 days in a 4 NaOH solution, without significant loss of ion exchange capacity. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Recommanded Product: 5036-48-6

The Article related to polyepichlorohydrin polyarylene ether ketone anion exchange membrane, anion exchange membrane, paek, crosslinking, imidazole, ion conductivity, Electrochemical, Radiational, and Thermal Energy Technology: Energy Sources and other aspects.Recommanded Product: 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On August 17, 2021, Le, My Linh; Rawlings, Dakota; Danielsen, Scott P. O.; Kennard, Rhiannon M.; Chabinyc, Michael L.; Segalman, Rachel A. published an article.Product Details of 5036-48-6 The title of the article was Aqueous Formulation of Concentrated Semiconductive Fluid Using Polyelectrolyte Coacervation. And the article contained the following:

Conjugated polyelectrolytes (CPEs), which combine π-conjugated backbones with ionic side chains, are intrinsically soluble in polar solvents and have demonstrated tunability with respect to solution processability and optoelectronic performance. However, this class of polymers often suffers from limited solubility in water. Here, polyelectrolyte coacervation was utilized for aqueous processing of conjugated polymers at extremely high polymer loading. Sampling various mixing conditions, compositions that enable the formation of complex coacervates of an alkoxysulfonate-substituted PEDOT (PEDOT-S) with poly(3-methyl-1-propylimidazolylacrylamide) (PA-MPI) were identified. The resulting coacervate is a viscous fluid containing 50% weight/volume polymer and can be readily blade-coated into films of 4 ± 0.5μm thickness. Subsequent acid doping of the film increased the elec. conductivity of the coacervate to twice that of a doped film of neat PEDOT-S. This higher conductivity of the doped coacervate film suggests an enhancement in charge carrier transport along PEDOT-S backbone, in agreement with spectroscopic data, which shows an enhancement in the conjugation length of PEDOT-S upon coacervation. This study illustrates the utilization of electrostatic interactions in aqueous processing of conjugated polymers, which will be useful in large-scale industrial processing of semiconductive materials using limited solvent and with added enhancements to optoelectronic properties. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Product Details of 5036-48-6

The Article related to polythiophene conjugated polymer polyelectrolyte coacervation semiconductive fluid, Physical Properties of Synthetic High Polymers: Polymer Solutions and Gels and other aspects.Product Details of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Brzeczek-Szafran, Alina; Wieclawik, Justyna; Barteczko, Natalia; Szelwicka, Anna; Byrne, Emily; Kolanowska, Anna; Swadzba Kwasny, Malgorzata; Chrobok, Anna published an article in 2021, the title of the article was Protic ionic liquids from di- or triamines: even cheaper Bronsted acidic catalysts.Synthetic Route of 5036-48-6 And the article contains the following content:

Dicationic and tricationic ionic liquids, synthesized by proton transfer from sulfuric acid and corresponding di- and triamines, were characterised and used as Bronsted acidic catalysts in biodiesel production It has been demonstrated that the new ionic liquids are less expensive than those based on monoamines (even on triethylamine) and are highly acidic. Their performance in a model catalytic esterification reaction surpassed that of sulfuric acid and other literature reports, due to the capability of the ionic liquids to absorb water while phase-separating the ester, thereby shifting the reaction equilibrium towards products. The overall catalytic performance was an interplay between acidity (quantified by Gutmann AN) and phys. properties: d. and viscosity, which enabled easy phase separation, thereby separating water from the ester. The substrate scope and recycling studies have demonstrated that the new ionic liquids are robust and recyclable catalysts. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Synthetic Route of 5036-48-6

The Article related to protic ionic liquid esterification reaction phys thermal catalytic property, Catalysis, Reaction Kinetics, and Inorganic Reaction Mechanisms: Catalysts and other aspects.Synthetic Route of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Jiang, Tuo; Bordi, Samuele; McMillan, Angus E.; Chen, Kuang-Yen; Saito, Fumito; Nichols, Paula L.; Wanner, Benedikt M.; Bode, Jeffrey W. published an article in 2021, the title of the article was An integrated console for capsule-based, automated organic synthesis.Application In Synthesis of N-(3-Aminopropyl)-imidazole And the article contains the following content:

Using a combination of reagent design, hardware engineering and a simple operating system, an instrument capable of executing complex organic reactions with prepacked capsules was provided. The machine conducted coupling reactions and delivered the purified products with minimal user involvement. Two desirable reaction classes – the synthesis of saturated N-heterocycles and reductive amination – were implemented, along with multi-step sequences that provided drug-like organic mols. in a fully automated manner. This system would serve as a console for developers to provide synthetic methods as integrated, user-friendly packages for conducting organic synthesis in a safe and convenient fashion. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Application In Synthesis of N-(3-Aminopropyl)-imidazole

The Article related to saturated heterocycle preparation, aldehyde amine capsule based automated organic synthesis, Heterocyclic Compounds (More Than One Hetero Atom): Eight- and Higher-Membered Rings and other aspects.Application In Synthesis of N-(3-Aminopropyl)-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On July 31, 2022, Karuk Elmas, Sukriye Nihan; Karagoz, Abdurrahman; Arslan, Fatma Nur; Yilmaz, Ibrahim published an article.Synthetic Route of 5036-48-6 The title of the article was Propylimidazole Functionalized Coumarin Derivative as Dual Responsive Fluorescent Chemoprobe for Picric Acid and Fe3+ Recognition: DFT and Natural Spring Water Applications. And the article contained the following:

A propylimidazole functionalized coumarin derivative (IPC) was fabricated for the first time and applied as a dual responsive fluorescent chemoprobe for sensitive and selective recognition of picric acid (PA) and Fe3+. Strong fluorescence quenching phenomena of the IPC were observed in H2O/ACN (5/95, volume/volume) medium (λem=408 nm) upon the additions of Fe3+ or PA. The fabricated dual responsive IPC offered good selectivity and sensitivity with the low limit of detection values (0.92μM for PA and 0.22μM for Fe3+) lower than the acceptable amounts of Fe3+ and PA by the international official authorities. The validation study for the chemoprobe IPC for PA and Fe3+ was also performed. The interaction phenomena of IPC with PA and Fe3+ based on the findings of a range of experiments were considered and DFT computations were done to verify their recognition mechanisms. The sensing phenomena of IPC towards PA (1:1) and Fe3+ (3:1) were confirmed by the MALDI TOF-MS, FT-IR, 1H-NMR titration and Job’s methods. Furthermore, the compound IPC was effectively applied as a fluorescent sensor for Fe3+ and PA detection in real natural spring water samples. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Synthetic Route of 5036-48-6

The Article related to propylimidazole coumarin preparation picricacid iron natural water fluorescent sensor, coumarin, dft, fluorescent sensor, iron, natural water, picric acid, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Luminescence and other aspects.Synthetic Route of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On February 14, 2008, McCormick, Kevin D.; Boyce, Christopher W.; Shih, Neng-Yang; Huang, Chia-Yu; Aslanian, Robert G.; Fevrier, Salem; Liang, Bo; Liu, Rong-Qiang; Liu, Ruiyan; Mangiaracina, Pietro; De Lera Ruiz, Manuel; Yu, Younong; Guise-Zawacki, Lisa; Zheng, Junying published a patent.SDS of cas: 50743-01-6 The title of the patent was Preparation of imidazolylmethylbenzoxazines and related compounds as α2c adrenoreceptor agonists.. And the patent contained the following:

Title compounds [I; A = (substituted) 5-membered heterocyclyl; X = O, S, SO, SO2, NR6; J1-J4 = N, NO, CR2; R2 = H, OH, halo, cyano, NO2, (substituted) alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl, heterocyclyl, etc.; R3 = H, O, (substituted) alkyl, alkoxy, alkenyl, alkenyloxy, alkynyl, cycloalkyl, aryl, heteroaryl, heterocyclyl, etc.; R4 = H, cyano, (substituted) alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl, aryl, aryloxy, aralkyl, heteroaryl, heterocyclyl, etc.; R6 = H, (substituted) alkyl, alkoxy, alkenyl, alkenyloxy, cycloalkyl, aryl, aryloxy, aralkyl, heteroaryl, heterocyclyl, heterocyclylalkyl, etc.; m = 1-5; n = 1-3; p = 0-4; with provisos], were prepared Thus, 2,3-dihydro-1,4-benzoxazine was stirred with imidazole-4-carboxaldehyde, NaBH(OAc)3, and HOAc in dichloroethane at 60° overnight to give 50% title compound (II). II and other I showed α2c adrenoreceptor agonist activity at ≥30% Emax (GTPγS assay). The experimental process involved the reaction of 5-Bromo-1H-imidazole-4-carbaldehyde(cas: 50743-01-6).SDS of cas: 50743-01-6

The Article related to imidazolylmethylbenzoxazine preparation adrenoreceptor agonist, rhinitis nasal congestion pain diarrhea glaucoma treatment benzoxazine imidazolylmethyl, Heterocyclic Compounds (More Than One Hetero Atom): Oxazines (Including Morpholine) and other aspects.SDS of cas: 50743-01-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On March 1, 2007, McCormick, Kevin D.; Boyce, Christopher W.; Shih, Neng-Yang; Aslanian, Robert G.; Mangiaracina, Pietro; De Lera Ruiz, Manuel; Yu, Younong; Biju, Purakkattle J.; Huang, Chia-Yu; Liang, Bo; Liu, Ruiyan; Liu, Rong-Qiang; Guise-Zawacki, Lisa published a patent.Category: imidazoles-derivatives The title of the patent was Preparation of imidazolylmethylbenzoxazines and related compounds as α2c adrenoreceptor agonists.. And the patent contained the following:

Title compounds [I; A = (substituted) 5-membered heterocyclyl; X = O, S, SO, SO2, NR6; J1-J4 = N, NO, CR2; R2 = H, OH, halo, cyano, NO2, (substituted) alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl, heterocyclyl, etc.; R3 = H, O, (substituted) alkyl, alkoxy, alkenyl, alkenyloxy, alkynyl, cycloalkyl, aryl, heteroaryl, heterocyclyl, etc.; R4 = H, cyano, (substituted) alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl, aryl, aryloxy, aralkyl, heteroaryl, heterocyclyl, etc.; R6 = H, (substituted) alkyl, alkoxy, alkenyl, alkenyloxy, cycloalkyl, aryl, aryloxy, aralkyl, heteroaryl, heterocyclyl, heterocyclylalkyl, etc.; m = 1-5; n = 1-3; p = 0-4; with provisos], were prepared Thus, 2,3-dihydro-1,4-benzoxazine was stirred with imidazole-4-carboxaldehyde, NaBH(OAc)3, and HOAc in dichloroethane at 60° overnight to give 50% title compound (II). II and other I showed α2c adrenoreceptor agonist activity at ≥30% Emax (GTPγS assay). The experimental process involved the reaction of 5-Bromo-1H-imidazole-4-carbaldehyde(cas: 50743-01-6).Category: imidazoles-derivatives

The Article related to imidazolylmethylbenzoxazine preparation adrenoreceptor agonist, rhinitis nasal congestion pain diarrhea glaucoma treatment benzoxazine imidazolylmethyl, Heterocyclic Compounds (More Than One Hetero Atom): Oxazines (Including Morpholine) and other aspects.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On February 3, 2021, Du, Liang; Nosratabad, Neda Arabzadeh; Jin, Zhicheng; Zhang, Chengqi; Wang, Sisi; Chen, Banghao; Mattoussi, Hedi published an article.HPLC of Formula: 5036-48-6 The title of the article was Luminescent Quantum Dots Stabilized by N-Heterocyclic Carbene Polymer Ligands. And the article contained the following:

We have tested the ability of N-heterocyclic carbene (NHC)-modified ligands to coordinate and stabilize luminescent CdSe-ZnS core-shell quantum dot (QD) dispersions in hydrophilic media. In particular, we probed the effects of ligand structure and coordination number on the coating affinity to the nanocrystals. We find that such NHC-based ligands rapidly coordinate onto the QDs (requiring ~5-10 min of reaction time), which reflects the soft Lewis base nature of the NHC groups, with its two electrons sharing capacity. Removal of the hydrophobic cap and promotion of carbene-driven coordination on the nanocrystals have been verified by 1H NMR spectroscopy, while 13C NMR was used to identify the formation of carbene-Zn complexes. The newly coated QD dispersions exhibit great long-term colloidal stability over a wide range of conditions. Addnl., we find that coordination onto the QD surfaces affects the optical and spectroscopic properties of the nanocrystals. These include a size-dependent red-shift of the absorption and fluorescence spectra and a pronounced increase in the measured fluorescence intensity when the samples are stored under white light exposure compared to those stored in the dark. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).HPLC of Formula: 5036-48-6

The Article related to luminescent quantum dot stabilized heterocyclic carbene polymer ligand, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Luminescence and other aspects.HPLC of Formula: 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On November 26, 2020, Aspnes, Gary E.; Bagley, Scott W.; Curto, John M.; Dowling, Matthew; Edmonds, David James; Fernando, Dilinie; Flanagan, Mark E.; Futatsugi, Kentaro; Griffith, David Andrew; Huard, Kim; Ingle, Gajendra; Jiao, Wenhua; Lacasse, Shawn M.; Lian, Yajing; Limberakis, Chris; Londregan, Allyn T.; Mathiowetz, Alan M.; Piotrowski, David Walter; Ruggeri, Roger B.; Wiglesworth, Kristin published a patent.Application In Synthesis of (1-Ethyl-1H-imidazol-5-yl)methanamine dihydrochloride The title of the patent was Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases and their preparation. And the patent contained the following:

The invention provides a new combination comprising (1) a GLP-1R agonist and (2) an ACC inhibitor or a DGAT2 inhibitor, or a KHK inhibitor or FXR agonist. The invention further provides new methods for treating diseases and disorders, for example, fatty liver, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, nonalcoholic steatohepatitis with liver fibrosis, nonalcoholic steatohepatitis with cirrhosis, and nonalcoholic steatohepatitis with cirrhosis and with hepatocellular carcinoma or with a metabolic-related disease, obesity, and type 2 diabetes, for example, using the new combination described herein. Example compound I•TFA was prepared by a multistep procedure (procedure given). The invention compounds were evaluated for their GLP-1R agonistic activity (some data given). The experimental process involved the reaction of (1-Ethyl-1H-imidazol-5-yl)methanamine dihydrochloride(cas: 1255717-13-5).Application In Synthesis of (1-Ethyl-1H-imidazol-5-yl)methanamine dihydrochloride

The Article related to benzodioxole preparation glp 1r agonist treatment nash nafld, Heterocyclic Compounds (More Than One Hetero Atom): Dioxoles, Oxathioles, Dithioles and other aspects.Application In Synthesis of (1-Ethyl-1H-imidazol-5-yl)methanamine dihydrochloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Demirayak, Seref; Ogretir, Cemil published an article in 1990, the title of the article was Proton-loss behaviors of some benzimidazole derivatives and their Hammett relationships.Synthetic Route of 5709-67-1 And the article contains the following content:

The proton-loss acidity constants, pKa, of 39 (un)substituted benzimidazole derivatives were determined by UV-visible spectroscopy. The calculated ΔpKa values were plotted vs. δm values to get Hammett graphs, and the results were discussed. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Synthetic Route of 5709-67-1

The Article related to lfer acidity benzimidazole, Physical Organic Chemistry: Acid-Base, Tautomerism, and Other Equilibrium Studies and other aspects.Synthetic Route of 5709-67-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem