Tag: 100-200

Strengthened adsorption and corrosion inhibition of new single imidazole-type ionic liquid molecules to copper surface in sulfuric acid solution by molecular aggregation was written by Shi, Yueting;Fu, Yan;Xu, Shenying;Huang, Haijun;Zhang, Shengtao;Wang, Zhenqiang;Li, Wenpo;Li, Hongru;Gao, Fang. And the article was included in Journal of Molecular Liquids in 2021.Recommanded Product: 21252-69-7 This article mentions the following:

This study proposes to use mol. aggregation method of organic ionic liquid mols. (OILMs) to intensify adsorption and corrosion inhibition to copper surface in sulfuric acid solution Three new single imidazole-type OILMs including long carbon chain were synthesized, which were characterized by different methods such as NMR (NMR) and elemental anal. The results suggest that the OILMs could process regular mol. assembly in sulfuric acid solution The formed OILMs aggregates have been shown dependence on the OILMs concentrations and aggregation time. The chem. adsorption of the OILMs aggregates on copper surface was demonstrated by various means including attenuated total reflection IR spectroscopy (ATR-IR), XPS, X-ray diffraction (XRD), and spectroscopic ellipsometry and contacting angles, and at. force microscopy (AFM) as well as SEM (SEM) imaging. Thus, the hydrophobic adsorption layers of the OILMs aggregates were yielded on copper surface. The electrochem. survey suggests that the OILMs aggregates present nice corrosion resistance effect to copper in sulfuric acid solution (the maximal corrosion inhibition efficiency, >93%). The results were further understood by the theor. simulation computation. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Recommanded Product: 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Recommanded Product: 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

An efficient process for pretreatment of lignocelluloses in functional ionic liquids was written by Dong, Shi-Jia;Zhang, Bi-Xian;Gao, Yun-Fei;Hu, Xiao-Mei. And the article was included in International Journal of Polymer Science in 2015.Safety of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

The complex structure of the lignocelluloses is the main obstacle in the conversion of lignocellulosic biomass into valuable products. Ionic liquids provide the opportunities for their efficient pretreatment for biomass. Therefore, in this work, pretreatment of corn stalk was carried out in ultrasonic-assisted ionic liquid including 1-butyl-3-methylimidazolium chloride [BMIM]Cl, 1-H-3-methylimidazolium chloride [HMIM]Cl, and 1-(1-propylsulfonic)-3-imidazolium chloride [HSO₃-pMIM]Cl at 70掳C for 2 h.We compared the pretreatments by ionic liquid with and without the addition of deionized water. Fourier transform IR spectroscopy (FTIR) and SEM were employed to analyze the chem. characteristics of regenerated cellulose-rich materials. [HMIM]Cl and [HSO₃-pMIM]Cl were effective in lignin extraction to obtain cellulose-rich materials. FTIR anal. and SEM anal. indicated the effective lignin removal and the reduced crystallinity of cellulose-rich materials. Enzymic hydrolysis of cellulose-rich materials was performed efficiently. High yields of reducing sugar and glucose were obtained when the corn stalk was pretreated by [HMIM]Cl and [HSO₃-pMIM]Cl. Ionic liquids provided the ideal environment for lignin extraction and enzymic hydrolysis of corn stalk and [HMIM]Cl and [HSO₃-pMIM]Cl proved the most efficient ionic liquids This simple and environmentally acceptable method has a great potential for the preparation of bioethanol for industrial production In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Safety of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Safety of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Pd/[C₂NH₂mim][Br] Thin Film Versus Pd/[C₈mim][Cl] or Pd/[C₈mim][BF₄]: Catalytic Applications in Electrooxidation of Methanol, p-Nitrophenol Reduction and C-C Coupling Reaction was written by Gheitasi Zarooni, Mahtab;Hoseini, S. Jafar;Bahrami, Mehrangiz;Roushani, Mahmoud;Nabavizadeh, S. Masoud. And the article was included in Journal of Inorganic and Organometallic Polymers and Materials in 2020.Quality Control of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

In this study, different ionic liquids including 1-aminoethyl-3-methyl-imidazolium bromide [C₂NH₂mim][Br] (1), 1-methyl-3-octylimidazolium chloride [C₈mim][Cl] (2) and 1-methyl-3-octylimidazolium tetrafluoroborate [C₈mim][BF₄] (3) were applied to stabilize Pd nanoparticles (NPs) at toluene/water interface as thin films. Field emission-SEM (FE-SEM) images showed puckered chains of ionic liquid (1) around the Pd NPs as flower nanostructures. Transmission electron microscopy (TEM) image of Pd/1 showed clearly core-shell nanostructures. Furthermore, applications of Pd/1, Pd/2 and Pd/3 were investigated in the Suzuki-Miyaura C-C coupling reaction in the presence and absence of ultrasonic waves, hydrogenation catalysis of p-nitrophenol reduction and methanol oxidation reaction. Interestingly, J_f (forwarding c.d. due to methanol oxidation) was observed only for Pd/1. We believe that interactions of -NH₂ and imidazolium groups of ionic liquid 1 with Pd particles are very important in producing of puckered shells around the Pd NPs. Injection of electron d. from -NH₂ group and Br^– of ionic liquid 1 to Pd content tends to Pd be softer than other ionic liquids (2 or 3). This effect weakens the strength of Pd-O and facilitates the intermol. reductive elimination between Pd-O and Pd-C鈮僌 in rate-determining step of methanol oxidation to produce CO₂ product. However, electron releasing group accelerates the increasement in neg. charge d. of metal accelerates intramol. or intermol. reduction elimination. Graphic Abstract: Stabilization of Pd nanoparticles from organometallic precursor in the presence of various ionic liquids is investigated. The obtained Pd/ionic liquid thin films were applied in catalytic reactions such as Suzuki-Miyaura C-C coupling reaction, p-nitrophenol reduction and methanol oxidation process for fuel cells. In spite of Pd nanoparticle thin films used for methanol oxidation reaction that exhibit no considerable methanol oxidation, these catalysts exhibit good electrocatalytic activity. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Quality Control of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Quality Control of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of novel cationic copolymer acrylamide/acrylic acid ester by single electron transfer living radical polymerization in aqueous solution was written by Ding, Wei;Liu, Kang;Luan, Huoxin;Yu, Tao;Qu, Guangmiao. And the article was included in Yingyong Huaxue in 2013.HPLC of Formula: 21252-69-7 This article mentions the following:

The imidazole, acrylonitrile, bromooctane were used to synthesize a new cationic polymerizable ionic liquid surfactant named chlorinated-1-octyl-3-(4-butylacrylate-based) imidazole (PMOIH₈). Using 2-chloropropylamide (MPC) as the initiator, Cu⁰ powder and tris-(2-dimethylamino ethyl) amine (Me₆-TREN) as the catalyst, a new kind of copolymer acrylamide/acrylic ester was synthesized via single electron transfer living radical polymerization (SET-LRP) of acrylamide with PMOIH₈. The resulting polymers were analyzed by FT-IR, MS and ¹H NMR, and the results showed that the polymers were target products. The relative mol. mass and the distribution of the resulting polymer were determined by GPC. The relative mol. mass of polymers is within the range of 2 脳 10³鈭?4 脳 10³, and the relative mol. mass distribution is within the range of 1.21鈭?.75. Various factors which might affect the SET-LRP such as catalyst and initiator were discussed. The results showed that as the amount of catalyst reduced, the polymerization rate decreased and the polymerization rate constant (k_p^app) reduced from 0.0168 min^-1 to 0.0065 min^-1, while the relative mol. mass distribution M_w/M_n increased from 1.25鈭?.71 to 1.32鈭?.75, and the initiator efficiency decreased, I_eff = 90.24%. As the amount of initiator increased, the relative mol. mass distribution of the resulting polymer was narrower with M_w/M_n reduced from 1.25鈭?.71 to 1.21鈭?.68, while the polymerization rate constant(k_p^app) increased from 0.0168 min^-1 to 0.0201 min^-1, and the initiator efficiency increased, I_eff = 93.17%. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7HPLC of Formula: 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. HPLC of Formula: 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Proton nuclear magnetic resonance spectra of aryl and mono- and disubstituted N-methylazoles was written by Butler, Richard Noel. And the article was included in Canadian Journal of Chemistry in 1973.Recommanded Product: 3034-41-1 This article mentions the following:

Proton NMR spectra of substituted azoles, e.g., methylpyrrole, imidazoles, pyrazoles, etc., are compared. The influence of the azole ring on the chem. shifts of phenyl protons is discussed. A correlation between N-Me chem. shifts and the structural characteristics of the N-Me group in mono- and disubstituted azoles is noted. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Recommanded Product: 3034-41-1).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Recommanded Product: 3034-41-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of heteroxanthine from a derivative of imidazole was written by Sarasin, J.;Wegmann, E.. And the article was included in Helvetica Chimica Acta in 1924.Application In Synthesis of 1-Methyl-4-nitroimidazole This article mentions the following:

S. and W. describe a new synthesis of 7-methylxanthine from an imidazole derivative, by closing the pyrimidine ring, an operation which has not been previously effected. 1-Methyl-4-nitro-5-chloroimidazole (I) is obtained in theoretical yield from 1-methyl-5-chloroimidazole (b. 200°) (II) by dissolving in dilute HNO₃ to form the nitrate, treating the latter with cold concentrated H₂SO₄, heating the mixture on the water bath for 2 hrs., and pouring the product on ice; it m. 147-8°, and is insoluble in acids and dilute alkalies. The isomeric 1-methyl-5-nitro-4-chloroimidazole (III), obtained by the same method from 1-methyl-4-chloroimidazole; m. 77-8°. I and III are reduced at 0° by Sn and HCl to the corresponding methylchloroaminoimidazoles which were not obtained in the pure state. I heated for several hrs. on the H₂O bath in EtOH with 2 mols. KCN and 0.1 mol. KI yields 85% 1-methyl-4-nitro-5-cyanoimidazole (IV), m. 141-2°, insoluble in acids and dilute alkalies. 1-Methyl-4-nitroimidazole-5-carboxamide (V), obtained in 90% yield when IV is heated for 2 hrs. on the H₂O bath with 8 times its weight of concentrated H₂SO₄ and the product is poured on ice, m. 257-8° (decomposes), insoluble in acids and alkalies, saponified with great difficulty; a small amount of the acid (VI) is obtained by prolonged action of concentrated HCl. VI m. 160° with evolution of CO₂ and formation of 1-methyl-4-nitroimidazole (VII), m. 133-40°, which is also obtained by heating V in a sealed tube at 120° with HCl. Reduction of VII by Sn and HCl at 0° and hydrolysis of the product by heating under pressure with HCl, gives NH₄Cl and sarcosine-HCl, m. 168-9°; this reaction establishes the constitution of II and VII. V is reduced at 0° by Sn and HCl to the corresponding amine, 1-methyl-4-aminoimidazole-5-carboxamide (VIII), m. 184-5°, decomposed when heated with water or dilute alkalies with evolution of NH₃; HCl salt, m. 214-5°. 7-Methylxanthine (heteroxanthine) obtained in 38% yield by heating 0.4 g. of VIII for 8 hrs. in a sealed tube at 160-70° with an equal weight of CO(OEt)₂, m. 380° (browning and evolution of gas). A mixture of the substance with heteroxanthine prepared from theobromine melts at the same temperature The murexide reaction is given with KClO₃ and HCl. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Application In Synthesis of 1-Methyl-4-nitroimidazole).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Application In Synthesis of 1-Methyl-4-nitroimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A regiospecific rearrangement of 4(5)-substituted 2-phenacylthio-1H-imidazoles to 4-substituted 2-mercapto-1-phenacyl-1H-imidazoles was written by Chakrabarti, Jiban K.;Smith, Colin W.. And the article was included in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) in 1991.Formula: C6H8N2O2S This article mentions the following:

4(5)-Substituted 2-phenacylthio-1H-imidazoles I (R = CO₂Et, Ph) thermally rearrange to give 2-mercapto-1-phenacyl-1H-imidazoles II. In the experiment, the researchers used many compounds, for example, Ethyl 2-mercapto-1H-imidazole-4-carboxylate (cas: 64038-64-8Formula: C6H8N2O2S).

Ethyl 2-mercapto-1H-imidazole-4-carboxylate (cas: 64038-64-8) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Formula: C6H8N2O2S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Reactions of organic anions. Part 143. Vicarious nucleophilic substitution of hydrogen in imidazole derivatives was written by Makosza, Mieczyslaw;Kwast, Ewa. And the article was included in Bulletin of the Polish Academy of Sciences, Chemistry in 1987.Quality Control of 1-Methyl-4-nitroimidazole This article mentions the following:

Nitroderivatives of imidazole react with carbanions containing leaving groups at the carbanion center yielding products of vicarious nucleophilic substitution of H at positions activated by the nitro group. Thus, nitroimidazole I reacted with PhSO₂CH₂Cl in the presence of KOH in Me₂SO to give derivative II. Some aspects of the orientation pattern of substitution are discussed. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Quality Control of 1-Methyl-4-nitroimidazole).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Quality Control of 1-Methyl-4-nitroimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Poly(ionic liquid) Bridge Joining Smectic Lamellar Conducting Channels in Photoelectrochemical Devices as High-Performance Solid-State Electrolytes was written by Wang, Caihong;Li, Xueyong;Zhou, Jiwen;Tian, Wen;Ji, Junyi;Wu, Yong;Tan, Shuai. And the article was included in ACS Applied Energy Materials in 2021.Recommanded Product: 1632-83-3 This article mentions the following:

Nanostructured ionic liquid crystals have emerged as promising electrolytes with the potential to satisfy the demands of both efficient charge transport and stability over conventional liquid electrolytes for advanced energy devices. However, traditional methods via the macroscopic orientation of ionic liquid crystals for charge transport intensification can hardly be achieved during practical device applications. Herein, a simple method was proposed to spontaneously construct long-range continuous conducting channels for significantly improving the charge transport of ionic liquid crystals in the confined space of energy devices. A poly(imidazolium ionic liquid) was designed and in situ prepared in a smectic [C14MIm][I]-based electrolyte for photoelectrochem. device fabrication. The composite solid-state electrolyte self-assembled microphase-segregation nanostructures, wherein the poly(ionic liquid) aggregated at the boundaries of layered smectic polydomains. The imidazolium iodide ions in the poly(ionic liquid) acted as imbedded ion tunnels at domain interfaces via π-π stacking and ionic interaction, which facilitated the charge transport crossing the interfacial gaps to join the intradomain lamellar channels as thermally stable and long-range continuous charge transport pathways. By using the poly(ionic liquid) to bridge the domain-interfacial gaps, the ion conductivity of the ionic liquid crystals was up to 7 times increased with a maximum value of 2.0 x 10^-3 S cm^-1, and the derived dye-sensitized solar cell could operate stably at 70 °C with a 2-times enhancement and champion efficiency of 8.2%. The approach here was comparable but more processable to traditional methods via the macroscopical orientation of ionic liquid crystals for charge transport intensification within energy devices, which have great potential to develop high-performance solid-state electrolytes to achieve the best balance between efficiency and durability for energy devices. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Recommanded Product: 1632-83-3).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Recommanded Product: 1632-83-3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Nucleophilic Aromatic Substitution Reactions Described by the Local Electron Attachment Energy was written by Stenlid, Joakim H.;Brinck, Tore. And the article was included in Journal of Organic Chemistry in 2017.Recommanded Product: 3034-41-1 This article mentions the following:

A local multiorbital electrophilicity descriptor, the local electron attachment energy [E(r)], is used to study the nucleophilic aromatic substitution reactions of S_NAr and VNS (vicarious nucleophilic substitution). E(r) considers all virtual orbitals below the free electron limit and is determined on the mol. isodensity contour of 0.004 at units. Good (R² = 0.83) to excellent (R² = 0.98) correlations are found between descriptor values and exptl. reactivity data for six series of electron deficient arenes. These include homo- and heteroarenes, rings of five to six atoms, and a variety of fluorine, bromine, and hydride leaving groups. The solvent, temperature, and nucleophile are in addition varied across the series. The surface E(r) [E_S(r)] provides reactivity predictions better than those of transition-state calculations for a concerted S_NAr reaction with a bromine nucleofuge, gives correlations substantially stronger than those of LUMO energies, and is overall more reliable than the mol. electrostatic potential. Using E_S(r), one can identify the various electrophilic sites within a mol. and correctly predict isomeric distributions. Since the calculations of E_S(r) are computationally inexpensive, the descriptor offers fast but accurate reactivity predictions for the important nucleophilic aromatic substitution class of reactions. Applications in, e.g., drug discovery, synthesis, and toxicol. studies are envisaged. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Recommanded Product: 3034-41-1).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Recommanded Product: 3034-41-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem