Tag: 100-200

A comparison study on the properties of 1,3-dialkylimidazolium tetrafluoroborate salts prepared by halogen-free and traditional method was written by Wang, Ruifeng;Qi, Xiujuan;Liu, Shimin;He, Yude;Deng, Youquan. And the article was included in Journal of Molecular Liquids in 2016.Formula: C11H20N2 This article mentions the following:

A series of 1,3-dialkylimidazolium tetrafluoroborate salts had been prepared via one-step alkylation of N-alkylimidazole with trialkyloxonium salts and traditional two-step method, resp. The possible impurities in these ionic liquids (ILs) such as Cl^–, Br^–, Na⁺ and alkyl imidazoles were measured. Detailed characterizations of two approaches in the ILs properties and performances such as spectroscopic properties, phase behavior, viscosity, refractive index, and electrochem. properties were systemically conducted. The obtained results showed that the variety of synthesized methods resulted in the distinct changes in physicochem. properties for the same IL. Therein, the comparison of spectroscopic properties and phase behaviors for the employed ILs were emphasized. Furthermore, in most cases, the ILs prepared by traditional two-step possessed the higher viscosity, lower refractive index as well as lower ionic conductivity than that of ILs prepared by one-step. It was worth noting that the 1-decyl-3-ethylimidazolium tetrafluoroborate ([DEIm]BF₄) prepared with the traditional and trialkyloxonium methods resp. exhibited distinctly different phase and fluorescence behaviors. The reason might be attributed to the significant improvement on the purities of ILs by the one-step strategy. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Formula: C11H20N2).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Formula: C11H20N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

N-Monomethylation of Amines with Methanol by Syndiotactic Poly(aminostyrene)-supported Palladium Nanoparticle Catalyst was written by Jiang, Lei;Zhang, Xiaoyan;Wang, Yinran;Guo, Fang;Hou, Zhaomin. And the article was included in Asian Journal of Organic Chemistry in 2021.Quality Control of 1-Methylbenzimidazole This article mentions the following:

Palladium nanocatalyst supported on dimethylamino-functionalized syndiotactic polystyrene (Pd@sPSNMe₂) showed high activity and selectivity for the N-monomethylation of various primary amines RNH₂ (R = Ph, cyclohexyl, 3-(morpholin-4-yl)propyl, 2-(1H-indol-3-yl)ethyl, etc.) using methanol as methylation reagent under air to prepare monomethylated amines RNH(CH₃), 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole and N-methyl-1H-benzo[d]imidazole. The excellent catalytic performance could be associated with the ultrafine palladium nanoparticles and high amine-adsorbing capacity of the catalyst. The Pd@sPS-NMe₂ catalyst was highly robust, and could be easily recovered by filtration and reused more than ten times without decrease in activity and selectivity. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Quality Control of 1-Methylbenzimidazole).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Quality Control of 1-Methylbenzimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Permeability and selectivity of acid gases in supported conventional and novel imidazolium-based ionic liquid membranes was written by Akhmetshina, Alsu I.;Gumerova, Olesya R.;Atlaskin, Artem A.;Petukhov, Anton N.;Sazanova, Tatyana S.;Yanbikov, Nail R.;Nyuchev, Alexander V.;Razov, Evgeny N.;Vorotyntsev, Ilya V.. And the article was included in Separation and Purification Technology in 2017.Product Details of 35487-17-3 This article mentions the following:

The novel imidazolium salts based on bis(2-ethylhexyl) sulfosuccinate anion have been developed as ionic liquids (ILs) which can potentially be used as absorbents of acid gases. The transport of CO₂, H₂S, CH₄ and N₂ in a series of supported ionic liquid membranes (SILMs) with immobilized conventional (bmim[PF₆], bmim[BF₄], bmim[Tf₂N]) and novel ILs was investigated. The supported ionic liquid membrane containing 1-butyl-3-methylimidazolium bis(2-ethylhexyl) sulfosuccinate (bmim[doc]) yielded a very high H₂S solubility and, hence, H₂S/N₂ selectivity equal to 65. However, the permeability of acid gases through such a membrane had relatively low values varying in a range of 100-200 Barrer, whereas permeability for SILMs impregnated by conventional ILs achieved 565 Barrer. The most effective separation of CO₂ was observed for SILMs impregnated by bmim[BF₄] predominantly owing to solubility component of permeability. In order to estimate the stability of SILMs, the polymeric support surface properties such as free surface energy, surface topol. and roughness parameters were evaluated. Anal. of exptl. data revealed that among the tested ILs, bmim[BF₄] immobilized in porous polymeric support was more resistant to losses and determined the higher stability of membranes. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Product Details of 35487-17-3).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Product Details of 35487-17-3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Anisotropic ionic conductivity in fluorinated ionic liquid crystals suitable for optoelectronic applications was written by Abate, Antonio;Petrozza, Annamaria;Cavallo, Gabriella;Lanzani, Guglielmo;Matteucci, Francesco;Bruce, Duncan W.;Houbenov, Nikolay;Metrangolo, Pierangelo;Resnati, Giuseppe. And the article was included in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2013.Computed Properties of C11H20N2 This article mentions the following:

The authors report a library of thirteen fluorinated ionic liquids consisting of iodide salts of 1-alkyl-3-polyfluoroalkyl-imidazolium cations. By changing the length of the alkyl and polyfluoroalkyl pendants, particular combinations of these result in compounds showing a mesophase. The nature and the mol. arrangement of the mesophase are characterized by polarized optical microscopy and powder x-ray diffraction anal., among others. After the addition of I₂ to generate the I^–/I₃^– redox couple, anisotropic ionic conductivity takes place along preferential pathways in the lamellar structure of the mesophase. Notably, the addition of I₂ does not suppress the mesophase temperature range, contrary to previously reported systems. Also, the tendency of these materials to supercool allows the mol. arrangement in the mesophase to be retained in a solid film at ambient temperatures Finally, the authors demonstrate their applicability as a quasi-solid electrolyte by preparing dye-sensitized solar cells with power conversion efficiencies comparable to the previous reports. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Computed Properties of C11H20N2).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Computed Properties of C11H20N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Benzotriazole and related compounds as corrosion inhibitors for copper was written by Cotton, Joseph B.;Scholes, Ian R.. And the article was included in British Corrosion Journal in 1967.Reference of 4887-83-6 This article mentions the following:

With reference to the corrosion inhibition of Cu by benzotriazole and analogous compounds reacted with Cu+ and Cu2+ ions. Recent data and practical operational experience are detailed. Related compounds included those where 1 or 2 of the N atoms of benzotriazole are substituted by C or the labile H atom is replaced by a CH3 group, i.e. indazole, benzimidazole, indole, and methyl benzotriazole. Salt-spray testing showed only benzotriazole and indazole prevented staining and only the former retained tarnish-resistant properties after the treated Cu surface was washed with organic solvents; the N-H group and one another N atoms and an insoluble complex formation appear necessary. Substitutional studies in the benzene ring showed Cl or nitro-groups in the 5-position increased acidity of the labile H atom but did not affect inhibition effects; naphthotriazole behaved similarly but 5-hydroxy indazole and 4-methyl benzimidazole were less effective than the parent compounds Generally 5-membered heterocyclics, imidozole, 1,2,4-triazole, and pyrazole and their derivatives showed little inhibitive effect. The benzotriazole-CuCl2 reaction product had a metal-organic ratio of 1 atom Cu: 1 mol. of benzotriazole; it was diamagnetic, amorphous, or microcrystalline, probably with a basic formula C6H4N3Cu. Reaction with CuCl2 did not give a 2:1 benzotriazole:Cu ratio and the product had excess Cu, chloride and H2O. The surface film apparently forms a true metal surface bond and the complex is polymeric. Application aspects discussed include dipping procedure, its use for brass coiled strip protection out-of-doors, swabbing processes, the use of impregnated paper for protection, its application to maintain solderability on surfaces, its use with brass nickel, silver, etc. to stop stress corrosion, etc. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Reference of 4887-83-6).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Reference of 4887-83-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Organocatalytic Enantioselective Conjugate Alkynylation of β-Aminoenones: Access to Chiral β-Alkynyl-β-Amino Carbonyl Derivatives was written by Wang, Jian-Fei;Meng, Xin;Zhang, Chao-Huan;Yu, Chuan-Ming;Mao, Bin. And the article was included in Organic Letters in 2020.Application of 1632-83-3 This article mentions the following:

Readily available potassium alkynyltrifluoroborates were used for organocatalytic asym. conjugate alkynylation of β-enaminones. The interception of a modified binaphthol catalyst and in situ generated organodifluoroboranes proved important to access functionalized β-alkynyl-β-amino carbonyls and derivatives with improved chemo-reactivity and enantio-induction. Mechanistic studies revealed the impact of mol. sieves on efficiency and stereocontrol. The products undergo addnl. functionalization to yield a diverse set of valuable β-alkynyl-β-amino carbonyl scaffolds. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Application of 1632-83-3).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Application of 1632-83-3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Fe-BPsalan Complex-Catalyzed Asymmetric [4 + 2] Cycloaddition of Cyclopentadiene with α,β-Unsaturated Heterocycles was written by Chen, Kai-Ge;Lu, Hao;Zhou, Yi-Ming;Wan, Xiao-Long;Wang, Hao-Yang;Xu, Zhen-Jiang;Guo, Hai-Ming;Che, Chi-Ming. And the article was included in Journal of Organic Chemistry in 2022.Name: 1-(1-Methyl-1H-imidazol-2-yl)ethanone This article mentions the following:

An efficient iron-catalyzed asym. [4 + 2] cycloaddition of cyclopentadiene with α,β-unsaturated acyl imidazoles or 2-cinnamoylisoindoline-1,3-dione derivatives was developed to afford the addition products in high yield and selectivity. Interestingly, the absolute structures of the addition products were controlled by the auxiliaries via different coordination modes with the same type of catalyst. In the experiment, the researchers used many compounds, for example, 1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1Name: 1-(1-Methyl-1H-imidazol-2-yl)ethanone).

1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Name: 1-(1-Methyl-1H-imidazol-2-yl)ethanone

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Hierarchically structured polymeric ionic liquids and polyvinylpyrrolidone mat-fibers fabricated by electrospinning was written by Montolio, Silvia;Abarca, Gabriel;Porcar, Raul;Dupont, Jairton;Burguete, Maria Isabel;Garcia-Verdugo, Eduardo;Luis, Santiago V.. And the article was included in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2017.Formula: C11H20N2 This article mentions the following:

Different polymeric ionic liquids/polyvinylpyrrolidone (PILs/PVP) fiber membranes were prepared by electrospinning from the corresponding polymeric blends. Supramol. interpolymeric interactions between PILs and PVP seem to define not only the solution properties but also the final morphol. and performance of the mat-fibers. The fine tuning of the counter anion and the length of the alkyl chain allows modulating both their hydrophilic/hydrophobic properties and their morphol. In this way, it was possible to obtain materials with potential applications in different fields as highlighted by the promising results obtained for oil-water separation or for the synthesis and stabilization of AuNPs. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Formula: C11H20N2).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Formula: C11H20N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Inhibition of rat hepatic microsomal aminopyrine N-demethylase activity by benzimidazole derivatives. Quantitative structure-activity relationships was written by Murray, Michael;Ryan, Adrian J.;Little, Peter J.. And the article was included in Journal of Medicinal Chemistry in 1982.Synthetic Route of C8H8N2 This article mentions the following:

Eighty-two benzimidazole derivatives, some which were synthesized, were tested for the ability to inhibit cytochrome P-450 mediated enzyme activity, specifically aminopyrine N-demethylase  [9037-69-8], from phenobarbitone-induced rat hepatic microsomes. Using physicochem. parameters and multiple regression anal., a quant. structure-activity relationship (QSAR) that describes up to 87% of the data variance in terms of hydrophobic and electronic effects and the molar refractivity of the substituent in the 2-position of the benzimidazole ring is presented. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Synthetic Route of C8H8N2).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Synthetic Route of C8H8N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Assessing chemical toxicity of ionic liquids on Vibrio fischeri: Correlation with structure and composition was written by Montalban, Mercedes G.;Hidalgo, Juana M.;Collado-Gonzalez, Mar;Diaz Banos, F. Guillermo;Villora, Gloria. And the article was included in Chemosphere in 2016.Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

One of the most important properties of ionic liquids is their non-volatility, making them potentially “green” alternatives to volatile organic compounds However, they are widely soluble in water, meaning that they can be released into aquatic ecosystems and so contribute to water pollution. Nevertheless, although the toxicity of ILs has been widely assessed in the literature, the information is still scarce due to the great number of ionic liquids that have been synthesized. The present work reports the toxicity of twenty-nine imidazolium-, pyridinium- and ammonium-based ionic liquids towards the bioluminescent photobacterium Vibrio fischeri. When the effect of the type of anion, the length of the alkyl chain of the cation, the cation core and the presence of a functionalized side chain in the cation on ionic liquid toxicity were analyzed, the main influence was seen to be exercised by the alkyl chain length. A Quant. Structure-Activity Relationships-based method was used to compare the exptl. results with previously estimated values and very good agreement was obtained. A relationship between the toxicity, expressed as Log EC₅₀, and the 1-octanol-water partition coefficient was established. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem