Tag: 100-200

Evaluation of a simple disposable microband electrode device for amperometric gas sensing was written by Xiong, Linhongjia;Goodrich, Peter;Hardacre, Christopher;Compton, Richard G.. And the article was included in Sensors and Actuators, B: Chemical in 2013.Reference of 79917-89-8 This article mentions the following:

The authors report a simple and facile methodol. for constructing Pt (6.3 mm × 50 μm) and Cu (6.3 mm × 30 μm) annular microband electrodes for use in room temperature ionic liquids (RTILs) and propose their use for amperometric gas sensing. The suitability of microband electrodes for use in electrochem. anal. was examined in experiments on two systems. The 1st system studied to validate the electrochem. responses of the annular microband electrode was decamethylferrocene (DmFc), as a stable internal reference probe commonly used in ionic liquids, in [Pmim][NTf₂], where the diffusion coefficients of DmFc and DmFc⁺ and the standard electron rate constant for the DmFc/DmFc⁺ couple were determined through fitting chronoamperometric and cyclic voltammetric responses with relevant simulations. These values are independently compared with those collected from a com. available Pt microdisc electrode with excellent agreement. The 2nd system focuses on O₂ reduction in [Pmim][NTf₂], which is used as a model for gas sensing. The diffusion coefficients of O₂ and O₂^– and the electron transfer rate constant were again obtained using chronoamperometry and cyclic voltammetry, along with simulations. Results determined from the microbands are again consistent to those evaluated from the Pt microdisc electrode when compared these results from home-made microband and com. available microdisc electrodes. The fabricated annular microband electrodes are suitable for quant. measurements. Further the successful use of the Cu electrodes in the O₂ system suggests a cheap disposable sensor for gas detection. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Reference of 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Reference of 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Development of ionic liquid-mediated antibacterial cellulose-chitosan films was written by Zhou, Yonghui;Luo, Xiaolin;Huang, Liulian;Lin, Shan;Chen, Lihui. And the article was included in Journal of Biobased Materials and Bioenergy in 2015.HPLC of Formula: 35487-17-3 This article mentions the following:

The solubility of cellulose, chitosan and their composites has been investigated to understand their roles in the formulation of antibacterial cellulose-chitosan composite films and their contributions to the performance of the films. Antibacterial and homogeneous cellulose-chitosan composite films with high mech. property were successfully prepared by co-dissolving cellulose and chitosan in 1-ethyl-3-methylimidazolium acetate (EmimAc) ionic liquid The composite films were further characterized by using XRD, TGA, FTIR, SEM, mech. strength and antibacterial ability measurements. XRD anal. of the films suggested that the structure of crystalline as well as crystallinities of both polymers changed during the processes of dissolution and regeneration, although their solubility varies considerably. The developed films were thermally more stable than the regenerated cellulose or chitosan itself. Hydrogen bonding between cellulose and chitosan in the blend films was determined by FTIR. SEM images also revealed a homogeneous and compact structure of the blend films. In addition, cellulose-chitosan composite films showed highly inhibitory effects on the bacteria of E. coli. and S. aureus. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3HPLC of Formula: 35487-17-3).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.HPLC of Formula: 35487-17-3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Electronic structure-activity relationships for propenone derivatives. II. 2-Cinnamoylbenzimidazoles and 2-(β-benzoylvinyl)-1-methylbenzimidazoles was written by Oganesyan, E. T.;Pogrebnyak, A. V.;Shiryaev, I. N.;Saraf, A. S.;Ivashev, M. N.. And the article was included in Khimiko-Farmatsevticheskii Zhurnal in 1995.Application In Synthesis of 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde This article mentions the following:

Synthesis of the title propenone derivatives as well as their sedative and antiallergic activities as functions of their electronic structure are described. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4Application In Synthesis of 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde).

1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Application In Synthesis of 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

CO₂ as a C1 Source: B(C₆F₅)₃-Catalyzed Cyclization of o-Phenylene-diamines To Construct Benzimidazoles in the Presence of Hydrosilane was written by Zhang, Zhenbei;Sun, Qiangsheng;Xia, Chungu;Sun, Wei. And the article was included in Organic Letters in 2016.Computed Properties of C8H8N2 This article mentions the following:

The catalytic construction of benzimidazoles using CO₂ as a carbon source represents a facile and sustainable approach to obtaining these valuable compounds Herein, we describe the B(C₆F₅)₃-catalyzed synthesis of benzimidazoles via cyclization of o-phenylenediamines with CO₂ and PhSiH₃. This metal-free catalytic route achieves the desired products in high yield under convenient reaction conditions and is applicable to a broad substrate scope. A plausible mechanism for the reaction involving a frustrated Lewis pair pathway is proposed based on spectroscopic characterization (e.g., ¹³C NMR) of the reaction intermediates. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Computed Properties of C8H8N2).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Computed Properties of C8H8N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Radical Cascade Multicomponent Minisci Reactions with Diazo Compounds was written by Su, Yong-Liang;Liu, Geng-Xin;De Angelis, Luca;He, Ru;Al-Sayyed, Ammar;Schanze, Kirk S.;Hu, Wen-Hao;Qiu, Huang;Doyle, Michael P.. And the article was included in ACS Catalysis in 2022.Electric Literature of C8H8N2 This article mentions the following:

Based on the strategy of polarity reversal in the generation of free radicals derived from diazo compounds, R¹C(=N₂)R²[R¹ = ethoxycarbonyl, (benzyloxy)carbonyl, N,N-diethylcarbamoyl, etc.; R² = H, C(O)OMe] photocatalyzed multicomponent reactions (MCRs) of nitrogen aromatic heterocycles, e.g., 4-methylquinoline, alkenes R³CH=CH₂ [R³ = methoxymethyl, cyclohexyl, 4-[(furan-2-yl)carbonyloxy]butyl, etc.], and diazo compounds form functionalized derivatives e.g., Et 4-(4-methylquinolin-2-yl)-6-phenylhexanoate in good to high yields and exacting regioselectivities. The carbon radicals generated from the acceptor diazo compounds are electrophilic, and their selective additions with alkenes provide nucleophilic radicals, which enable the further rapid assembly with various heteroarenes. A delicate balance has been achieved between the activation of heteroarenes through protonation and the decomposition of diazo compounds by the same acid. This multicomponent Minisci reaction shows high functional group tolerance, especially in the incorporation of biol. active mols. Detailed mechanistic studies that include photophys. measurements elaborate this radical cascade reaction. Furthermore, this transformation provides new opportunities for versatile reactions of diazo compounds in radical cascade multicomponent coupling reactions. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Electric Literature of C8H8N2).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Electric Literature of C8H8N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

FTIR metabolomic fingerprint reveals different modes of action exerted by active pharmaceutical ingredient based ionic liquids (API-ILs) on Salmonella typhimurium was written by Mester, P.;Jehle, A. K.;Leeb, C.;Kalb, R.;Grunert, T.;Rossmanith, P.. And the article was included in RSC Advances in 2016.HPLC of Formula: 79917-89-8 This article mentions the following:

Since their incorporation into various chem. and biochem. processes, ionic liquids (ILs) have now been found useful for biomedical applications, including active pharmaceutical ingredients (APIs) such as antimicrobial agents or antibiotics. Recently, synergistic API-ILs with great potential have been reported, which show either increased antimicrobial activity or the ability to overcome bacterial resistance. In this study a total of 19 API-ILs, based on the antibiotic nalidixic acid, combined with different cation species, were investigated for synergistic effects against the important foodborne pathogen Salmonella. Furthermore, 19 resp. ILs with chloride as the anion were used to control the effects of the different cation species. The antimicrobial activities of all 38 ILs against six different Salmonella species, as well as two nalidixic acid-resistant S. typhimurium strains, were determined via the microbroth dilution assay. The response pattern of the main cellular constituents, namely proteins, carbohydrates, and lipids of the bacterial cells to the most promising API-ILs was further investigated by Fourier transform IR (FTIR) spectroscopy. While a number of active API-ILs based on nalidixic acid could be synthesized, no evidence for synergistic effects, such as increased antimicrobial activity or the ability to overcome resistance was found with either microbiol. or spectroscopic methods. However, it could be demonstrated for the first time that while the different IL species ([TC₈MA]⁺ and [TMC₁₆A]⁺) showed similar antimicrobial activity, the FTIR spectral patterns indicated changes in bacterial membrane fluidity suggesting different modes of action. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8HPLC of Formula: 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.HPLC of Formula: 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Pharmacophore optimization of imidazole chalcones to modulate microtubule dynamics was written by Karaj, Endri;Dlamini, Samkeliso;Koranne, Radhika;Sindi, Shaimaa H.;Perera, Lalith;Taylor, William R.;Viranga Tillekeratne, L. M.. And the article was included in Bioorganic Chemistry in 2022.Quality Control of 1-(1-Methyl-1H-imidazol-2-yl)ethanone This article mentions the following:

We recently reported a new class of imidazole-based chalcones as potential antimitotic agents. In view of their promising cytotoxic activity, a comprehensive structure-activity relationship (SAR) of these compounds was undertaken focusing on four major structural variations: the length of the mol., the Michael acceptor character, the nature and substitution pattern of ring B, and the nature of the amide functionality tethering ring B. These second-generation analogs (IBCs) demonstrated a superior bioactivity profile than the previously reported imidazole chalcones (referred to as IPEs). The analog IBC-2 with one less methylene group (nor series) and para-fluoro substituted ring B demonstrated the best cytotoxicity profile among the library of compounds A computational anal. of the NCI-60 data associated both IBCs and the previously reported IPEs with the privileged pharmacol. pharmacophore of chalcones. Interestingly, biol. studies suggest that the imidazole ring is essential for cytotoxic activity of the elongated chalcone analogs. Immunofluorescence studies revealed that IBC-2, unlike IPEs, has the ability to induce microtubule catastrophe independently of Aurora-B inhibition. The effects of IBC-2 on microtubule dynamics are similar to those of Nocodazole, but the cell cycle effects appear to be different. In-silico studies demonstrate that the members of the new series have the ability to bind to the colchicine binding site of β-tubulin with binding scores similar to those of IPEs, corresponding chalcones and Nocodazole. Although tubulin binding can partially explain the biol. effects of IBC-2, on-going target identification studies are aimed at further investigation of its biol. targets. In the experiment, the researchers used many compounds, for example, 1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1Quality Control of 1-(1-Methyl-1H-imidazol-2-yl)ethanone).

1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Quality Control of 1-(1-Methyl-1H-imidazol-2-yl)ethanone

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Cobalt-Catalyzed Cross-Coupling Reactions of Arylboronic Esters and Aryl Halides was written by Duong, Hung A.;Wu, Wenqin;Teo, Yu-Yuan. And the article was included in Organometallics in 2017.Reference of 25676-75-9 This article mentions the following:

An efficient cobalt catalyst system for the Suzuki-Miyaura cross-coupling reaction of arylboronic esters and aryl halides has been identified. In the presence of cobalt(II)/terpyridine catalyst and potassium methoxide, a diverse array of (hetero)biaryls have been prepared in moderate to excellent yields. In the experiment, the researchers used many compounds, for example, 4-Bromo-1-methylimidazole (cas: 25676-75-9Reference of 25676-75-9).

4-Bromo-1-methylimidazole (cas: 25676-75-9) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Reference of 25676-75-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Surface Modification of a Supported Pt Catalyst Using Ionic Liquids for Selective Hydrodeoxygenation of Phenols into Arenes under Mild Conditions was written by Ohta, Hidetoshi;Tobayashi, Kanako;Kuroo, Akihiro;Nakatsuka, Mao;Kobayashi, Hirokazu;Fukuoka, Atsushi;Hamasaka, Go;Uozumi, Yasuhiro;Murayama, Haruno;Tokunaga, Makoto;Hayashi, Minoru. And the article was included in Chemistry – A European Journal in 2019.Recommanded Product: 1-Octyl-1H-imidazole This article mentions the following:

The selective and efficient removal of oxygenated groups from lignin-derived phenols is a critical challenge to utilize lignin as a source for renewable aromatic chems. This report describes how surface modification of a zeolite-supported Pt catalyst using ionic liquids (ILs) remarkably increases selectivity for the hydrodeoxygenation (HDO) of phenols into arenes under mild reaction conditions using atm. pressure H₂. Unmodified Pt/H-ZSM-5 converts phenols into aliphatic species as the major products along with a slight amount of arenes (10 % selectivity). In contrast, the catalyst modified with an IL, 1-butyl-3-methylimidazolium triflate, keeps up to 76 % selectivity for arenes even at a nearly complete conversion of phenols. The IL on the surface of Pt catalyst may offer the adsorption of phenols in an edge-to-face manner onto the surface, thus accelerating the HDO without the ring hydrogenation. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Recommanded Product: 1-Octyl-1H-imidazole).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Recommanded Product: 1-Octyl-1H-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of methylimidazolium amine ionic liquid for ATRP polymerization system was written by Xue, Teng;Zhou, Jian;Fu, Tantan;Tang, Erjun;Zhao, Dishun. And the article was included in Huagong Xuebao (Chinese Edition) in 2016.Recommanded Product: 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

1-(Pr amine)ethyl-3-Me chloride ionic liquid ([N₂C₃MIM]Cl) was prepared on the base of N-methylimidazole by 1,2-dichloroethane to obtain the intermediates 1-chloro-ethyl-3-Me chloride ionic liquid ([CeMIM]Cl) and then reacting with 1,3-propanediamine. The chem. structure of [N₂C₃MIM]Cl was confirmed by FT-IR and ¹H NMR. [N₂C₃MIM]Cl possessed a lower REDOX potential (-0.522 V) through cyclic voltammetry measurement, [N₂C₃MIM]Cl presented a perfect coordination property compared with organic ligands. The obtained ionic liquid [N₂C₃MIM]Cl coordinated with CuBr was used to catalyze atom transfer radical polymerization (ATRP) of Me methacrylate (MMA) and it indicated by gel permeation chromatog. (GPC) that the coordination ionic liquid [N₂C₃MIM]Cl presented the perfect controllability to the ATRP reactions. The residues of Cu²⁺ in polymerization product PMMA was only 270 mg·kg^-1 by at. absorption spectrometry determination It showed that [N₂C₃MIM]Cl was conducive to the separation of catalyst from the obtained product compared with the traditional organic ligands. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Recommanded Product: 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Recommanded Product: 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem