Tag: 100-200

On May 31, 2021, Safiulina, A. M.; Lizunov, A. V.; Borisova, N. E.; Baulina, T. V.; Goryunov, E. I.; Goryunova, I. B.; Brel� V. K. published an article.Application of 5036-48-6 The title of the article was Extraction Properties of Diphenylposphorylureas with Aliphatic �Nitrogen-Containing Substituents. And the article contained the following:

Extraction of lanthanides and actinides from nitric acid solutions with N-(diphenylphosphoryl)-N�n-propylureas containing imidazolyl, diethylamino, pyrid-2-yl, 2-oxopyrrolidino fragments in the �position of the alkyl substituent has been studied. It has been shown that Ho(III) and Yb(III) related to the yttrium subgroup of lanthanides are extracted much better than La(III) and Nd(III) related to the cerium subgroup. N-(Diphenylphosphoryl)urea containing �(2-oxopyrrolidino)propyl fragment at the terminal nitrogen atom shows the best extraction properties. This dependence has been theor. explained by modeling complexation because the coordination of f-block element ion with amide oxygen atom is more preferable The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Application of 5036-48-6

The Article related to chlorodiphenylphosphine lanthanum uranium extraction distillation distribution, Placeholder for records without volume info and other aspects.Application of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On March 18, 2020, Rees, Kelly; Tran, Michael V.; Massey, Melissa; Kim, Hyungki; Krause, Katherine D.; Algar, W. Russ published an article.Name: N-(3-Aminopropyl)-imidazole The title of the article was Dextran-Functionalized Semiconductor Quantum Dot Bioconjugates for Bioanalysis and Imaging. And the article contained the following:

The prerequisites for maximizing the advantageous optical properties of colloidal semiconductor quantum dots (QDs) in biol. applications are effective surface functionalization and bioconjugation strategies. Functionalization with dextran has been highly successful with some nanoparticle materials, but has had very limited application with QDs. Here, we report the preparation, characterization, and proof-of-concept applications of dextran-functionalized QDs. Multiple approaches to dextran ligands were evaluated, including performance with respect to colloidal stability across a range of pH, nonspecific binding with proteins and cells, and microinjection into cells and viability assays. Multiple bioconjugation strategies were demonstrated and applied, including covalent coupling to develop a simple pH sensor, binding of polyhistidine-tagged peptides to the QD for energy transfer-based proteolytic activity assays, and binding with tetrameric antibody complexes (TACs) to enable a sandwich immunoassay and cell immunolabeling and imaging. Our results show that dextran ligands are highly promising for the functionalization of QDs, and that the design of the ligands is tailorable to help optimally meet the requirements of applications. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Name: N-(3-Aminopropyl)-imidazole

The Article related to sequence dextran semiconductor quantum dot bioconjugates bioanalysis imaging, Placeholder for records without volume info and other aspects.Name: N-(3-Aminopropyl)-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On June 22, 2022, Luo, Yi; Clabbers, Max T. B.; Qiao, Jian; Yuan, Zhiqing; Yang, Weimin; Zou, Xiaodong published an article.Product Details of 5036-48-6 The title of the article was Visualizing the Entire Range of Noncovalent Interactions in Nanocrystalline Hybrid Materials Using 3D Electron Diffraction. And the article contained the following:

Noncovalent interactions are essential in the formation and properties of a diverse range of hybrid materials. However, reliably identifying the noncovalent interactions in nanocrystalline materials remains challenging using conventional methods such as X-ray diffraction and spectroscopy. Here, we demonstrate that accurate at. positions including hydrogen atoms can be determined using three-dimensional electron diffraction (3D ED), from which the entire range of noncovalent interactions in a nanocrystalline aluminophosphate hybrid material SCM-34 are directly visualized. The protonation states of both the inorganic and organic components in SCM-34 are determined from the hydrogen positions. All noncovalent interactions, including hydrogen-bonding, electrostatic, ��stacking, and van der Waals interactions, are unambiguously identified, which provides detailed insights into the formation of the material. The 3D ED data also allow us to distinguish different types of covalent bonds based on their bond lengths and to identify an elongated terminal P = O �bond caused by noncovalent interactions. Our results show that 3D ED can be a powerful tool for resolving detailed noncovalent interactions in nanocrystalline materials. This can improve our understanding of hybrid systems and guide the development of novel functional materials. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Product Details of 5036-48-6

The Article related to noncovalent interaction nanocrystalline hybrid material electron diffraction, Placeholder for records without volume info and other aspects.Product Details of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On November 30, 2021, Slassi, Siham; Aarjane, Mohammed; Amine, Amina published an article.Formula: C6H11N3 The title of the article was A novel imidazole-derived Schiff base as selective and sensitive colorimetric chemosensor for fluorescent detection of Cu2+ in methanol with mixed aqueous medium. And the article contained the following:

A highly efficient, selective, sensitive, and colorimetric chemosensor SB for Cu2+ detection with turn-on fluorescence behavior in CH3-water solution was synthesized. A good enhancement of the intensity of fluorescence was detected by the incremental addition of Cu2+ after excitation at 286 nm. The fluorescence quantum yield (æ¡? of SB-Cu2+ was calculated for 0.41. The responsive mechanism of SB to copper ion is involved for on the combined effects of C-N isomerization and intramol. charge transfer (ICT) process and chelation-enhanced fluorescence (CHEF). The detection limit for the fluorescent chemosensor SB toward Cu2+ was 0.6 x 10-6 M. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Formula: C6H11N3

The Article related to imidazole schiff base colorimetric chemosensor fluorescent detection copper, Placeholder for records without volume info and other aspects.Formula: C6H11N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Latifi, Reza; Minnick, Jennifer L.; Quesne, Matthew G.; de Visser, Sam P.; Tahsini, Laleh published an article in 2020, the title of the article was Computational studies of DNA base repair mechanisms by nonheme iron dioxygenases: selective epoxidation and hydroxylation pathways.HPLC of Formula: 55662-66-3 And the article contains the following content:

DNA base repair mechanisms of alkylated DNA bases is an important reaction in chem. biol. and particularly in the human body. It is typically catalyzed by an ä¼?ketoglutarate-dependent nonheme iron dioxygenase named the AlkB repair enzyme. In this work we report a detailed computational study into the structure and reactivity of AlkB repair enzymes with alkylated DNA bases. In particular, we investigate the aliphatic hydroxylation and C=C epoxidation mechanisms of alkylated DNA bases by a high-valent iron(IV)-oxo intermediate. Our computational studies use quantum mechanics/mol. mechanics methods on full enzymic structures as well as cluster models on active site systems. The work shows that the iron(IV)-oxo species is rapidly formed after dioxygen binding to an iron(IV) center and passes a bicyclic ring structure as intermediate. Subsequent cluster models explore the mechanism of substrate hydroxylation and epoxidation of alkylated DNA bases. The work shows low energy barriers for substrate activation and consequently energetically feasible pathways are predicted. Overall, the work shows that a high-valent iron(IV)-oxo species can efficiently dealkylate alkylated DNA bases and return them into their original form. The experimental process involved the reaction of Imidazo[1,2-c]pyrimidin-5(6H)-one(cas: 55662-66-3).HPLC of Formula: 55662-66-3

The Article related to human dioxygenase alkb dna base repair mechanism epoxidation hydroxylation, Enzymes: Structure-Conformation-Active Site and other aspects.HPLC of Formula: 55662-66-3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On March 31, 2021, Leopoldino, Elder C.; Pinheiro, Gabriela; Alves, Ricardo J.; Gerola, Adriana; Souza, Bruno S. published an article.Electric Literature of 5036-48-6 The title of the article was Post-modified polymer with imidazole groups as an efficient and reusable heterogeneous catalyst for organophosphate degradation. And the article contained the following:

In this work, the com. polymer poly(ethylene-alt-maleic anhydride) was used as a platform for the preparation of an imidazole-rich polymeric catalyst (PEIIm) designed for organophosphate degradation The catalyst was prepared at gram-scale using simple and cost-effective steps and was characterized by 1H NMR, IR, CHN and TGA. PEIIm showed higher activity than the free imidazole towards the degradation of di-Et 2,4-dinitrophenylphosphate, an organophosphate model, and was recovered by centrifugation and reused without loss of activity. Importantly, experiments performed under excess of substrate demonstrate that true catalysis takes place. Solvent kinetic isotope effect indicates that the pendant imidazole groups attack the phosphorus atom to form a phosphorylated polymeric intermediate that is rapidly hydrolyzed, allowing for the catalyst regeneration. PEIIm was also employed in the degradation of toxic pesticide Et paraoxon, resulting in a reduction in its half-life from 780 days to 25 days at 25 掳C, pH 8.0. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Electric Literature of 5036-48-6

The Article related to imidazole group polymer heterogeneous catalyst organophosphate degradation, Placeholder for records without volume info and other aspects.Electric Literature of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Biswas, Sneha; Chowdhury, Tania; Ghosh, Avik; Das, Abhijit K.; Das, Debasis published an article in 2022, the title of the article was Effect of O-substitution in imidazole based Zn(II) dual fluorescent probes in the light of arsenate detection in potable water: a combined experimental and theoretical approach.Computed Properties of 5036-48-6 And the article contains the following content:

Efficient detection of arsenate (AsO43-) from contaminated drinking water extracted from underground has become a matter of utmost necessity and an exquisite challenge owing to the growing public health issue due to arsenicosis. In order to combat this we planned to detect arsenate with the naked eye under UV light using a novel chemosensor material whose structure and functioning as a sensor could be certified mechanistically. Hence we were encouraged to synthesize two differently O-substituted imidazole based homologous ligands: C1 (HL1 = 2-((E)-(3-(1H-imidazole-1-yl)propylimino)methyl)-6-ethoxyphenol) and C2 (HL2 = 2-((E)-(3-(1H-imidazole-1-yl)propylimino)methyl)-6-methoxyphenol). To accomplish the purposeful exploration of the luminescent sensor, we considered Chelation Enhanced Fluorescence (CHEF) and kept on searching for a metal cation that would be able to turn on the fluorescence of the ligands. Considering Zn(II) as the most suitable candidate, luminescent complexes D1 and D2 ({[Zn2(L1)2(I)2](DMF)} and [Zn2(L2)2(I)2](DMF), resp.) were synthesized and characterized by SXRD, UV-Vis, FT-IR, and photoluminescence spectroscopy. In spite of the resemblance in the solid state structures of D1 and D2, the selective response of D1 towards arsenate with high quenching constants (2.13 x 106), unlike D2, has been demonstrated mechanistically with steady state and time resolved fluorescence titration, solution phase ESI-MS spectral anal. and DFT studies. The selectivity and sensitivity of the sensor D1 explicitly make this material a potent candidate for arsenate detection due to its very low detection limit (8.2 ppb), low cost and user friendly characteristics. Real life implementation of this work in a test strip is expected to prove beneficial for public health to identify arsenate polluted water. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Computed Properties of 5036-48-6

The Article related to zinc dual fluorescent probe arsenate detection density functional theory, Placeholder for records without volume info and other aspects.Computed Properties of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On April 30, 2022, Pham, Julie; Forget, Amelie; Bridonneau, Nathalie; Mattana, Giorgio; Stavrinidou, Eleni; Zrig, Samia; Piro, Benoit; Noel, Vincent published an article.Recommanded Product: N-(3-Aminopropyl)-imidazole The title of the article was In vivo electrochemically-assisted polymerization of conjugated functionalized terthiophenes inside the vascular system of a plant. And the article contained the following:

We investigate the possibility of producing biofuel cell electrode materials in vivo by injecting the reagents directly into plant tissues. We first introduce model electroactive substances Fe(CN)64- and Ru(NH3)63+ into a Nicotiana tabacum leaf. In situ electrochem. measurements make it possible to trace the distribution of these substances. As well as mapping the vascular content, electrochem. can be used to trigger reactions directly inside the plant. The injection of thiophene (T) and ethylenedioxythiophene (E)-based trimers (ETE) anchoring an Os(2,2�bipyridine)2(1-(3-aminopropyl)-imidazole)Cl Os-complex followed by the application of anodic polarization triggers a polymerization reaction in the region of the plant vascular system containing the monomer, showing that it is possible to generate electroactive organic macromols. locally in vivo. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Recommanded Product: N-(3-Aminopropyl)-imidazole

The Article related to terthiophene injection anodic polarization plant vascular polymerization, Placeholder for records without volume info and other aspects.Recommanded Product: N-(3-Aminopropyl)-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On August 19, 2013, Li, Deyu; Fedeles, Bogdan I.; Shrivastav, Nidhi; Delaney, James C.; Yang, Xuedong; Wong, Cintyu; Drennan, Catherine L.; Essigmann, John M. published an article.Safety of Imidazo[1,2-c]pyrimidin-5(6H)-one The title of the article was Removal of N-Alkyl Modifications from N2-Alkylguanine and N4-Alkylcytosine in DNA by the Adaptive Response Protein AlkB. And the article contained the following:

The AlkB enzyme is an Fe(II)- and ä¼?ketoglutarate-dependent dioxygenase that repairs DNA alkyl lesions by a direct reversal of damage mechanism as part of the adaptive response in E. coli. The reported substrate scope of AlkB includes simple DNA alkyl adducts, such as 1-methyladenine, 3-methylcytosine, 3-ethylcytosine, 1-methylguanine, 3-methylthymine, and N6-methyladenine, as well as more complex DNA adducts, such as 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 1,N6-ethanoadenine. Previous studies have revealed, in a piecemeal way, that AlkB has an impressive repertoire of substrates. The present study makes two additions to this list, showing that alkyl adducts on the N2 position of guanine and N4 position of cytosine are also substrates for AlkB. Using high resolution ESI-TOF mass spectrometry, we show that AlkB has the biochem. capability to repair in vitro N2-methylguanine, N2-ethylguanine, N2-furan-2-yl-methylguanine, N2-tetrahydrofuran-2-yl-methylguanine, and N4-methylcytosine in ssDNA but not in dsDNA. When viewed together with previous work, the exptl. data herein demonstrate that AlkB is able to repair all simple N-alkyl adducts occurring at the Watson-Crick base pairing interface of the four DNA bases, confirming AlkB as a versatile gatekeeper of genomic integrity under alkylation stress. The experimental process involved the reaction of Imidazo[1,2-c]pyrimidin-5(6H)-one(cas: 55662-66-3).Safety of Imidazo[1,2-c]pyrimidin-5(6H)-one

The Article related to alkyl alkylguanine alkylcytosine dna adaptation protein alkb dioxygenase, Enzymes: Analysis (Determination-Detection) and other aspects.Safety of Imidazo[1,2-c]pyrimidin-5(6H)-one

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

On May 11, 2018, Gu, Zhen; Yu, Jicheng published a patent.Name: 2-Nitro-1H-benzo[d]imidazole The title of the patent was Patch loaded with dual-sensitive vesicles for enhanced glucose-responsive insulin delivery. And the patent contained the following:

A composition comprising an amphiphilic polymeric material that is both hydrogen peroxide- and hypoxia-sensitive is described. The composition can further include a glucose-oxidizing enzyme and insulin, a bioactive derivative thereof, and/or another therapeutic agent (e.g., another diabetes treatment agent). The polymeric material can form vesicles that comprise single or multiple layers of the polymeric material that enclose the glucose-oxidizing enzyme and the insulin, bioactive derivative and/or other therapeutic agent. The vesicles can be loaded into microneedles to, for example, prepare microneedle arrays for skin patches. Methods of delivering insulin to a subject using the compositions, vesicles, microneedles, and/or microneedle array skin patches are also described. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Name: 2-Nitro-1H-benzo[d]imidazole

The Article related to patch dual sensitive vesicle insulin delivery polymer preparation, Pharmaceuticals: Formulation and Compounding and other aspects.Name: 2-Nitro-1H-benzo[d]imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem