Tag: 200-300

In 2019,Journal of Molecular Liquids included an article by Aghaie, Mahsa; Rezaei, Nima; Zendehboudi, Sohrab. Computed Properties of C8H15BF4N2. The article was titled 《Assessment of carbon dioxide solubility in ionic liquid/toluene/water systems by extended PR and PC-SAFT EOSs: Carbon capture implication》. The information in the text is summarized as follows:

Recently, there has been a growing interest in CO2 capture using ionic liquids (ILs). To determine the CO2 absorption potential of ILs and their selectivity in the presence of other gaseous components in the mixture, the solubility of ILs at various operating conditions and the influence of impurities/additives such as water and toluene should be evaluated. Carbon capture capacity of the ILs can be examined using various methods such as experiments, thermodn. approaches including Equations of State (EOSs), and mol.-based modeling. In this research work, the extended Peng-Robinson (PR) and Perturbed-Chain Statistical Associating Fluid Theory (PC-SAFT) EOSs are utilized to assess the solubility and selectivity of CO2 in ILs through comparing the modeling results with exptl. data. PC-SAFT and PR parameters are determined by employing the exptl. d. data. Modeling results reveal that the solubility values estimated by the PC-SAFT due to considering the association effects have a lower deviation (or a better performance) than PR EOS based on the magnitudes of Absolute Average Deviation (AAD %). The AAD (%) for [bmim][BF4], [bmim][PF6], [bmim][Tf2N], [hmim][Tf2N], [hmim][FAP], and [hmim][FAP] are calculated using PR EOS and PC-SAFT EOS, which are 2-5.7% and 3-7.5%, resp. Furthermore, ternary systems of CO2 + ILs + water and CO2 + ILs + toluene are modeled to determine the effect of water and toluene on the gas solubility in ILs and viscosity of ILs with PC-SAFT EOS. Based on the results, low concentrations of water (0.1 wt%) have a negligible influence on the CO2 solubility in ILs. However, with increasing the water concentration, the solubility of water reduces significantly. On the other hand, the viscosity of ILs is reduced with increasing the water concentration Viscosity reduction in the hydrophilic ILs is significant. It seems promising to add water up to 10 wt% to hydrophilic ILs, since a decrease in the viscosity to an amount close to the viscosity of water and a decrease in solubility by 9% are experienced. Finally, the selectivity of [hmim][Tf2N] in separation of CO2 from mixtures containing H2S, SO2, CH4, and H2 are reported. Based on the results, [hmim][Tf2N] is not appropriate for separation of CO2 from streams with a high concentration of H2S and SO2 gases. In the experimental materials used by the author, we found 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Computed Properties of C8H15BF4N2)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. A multidisciplinary study on lonic liquids is emerging, including chemistry, materials science, chemical engineering, and environmental science. More specifically, some important fundamental viewpoints are now different from the original concepts, as insights into the nature of lonic liquids become deeper. For example, the physicochemical properties of lonic liquids are now recognized as ranging broadly from the oft quoted “nonvolatile, non-flammable, and air and water stable” to those that are distinctly volatile, flammable, and unstable. Computed Properties of C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

SDS of cas: 58-85-5In 2019 ,《High doses of biotin can interfere with immunoassays that use biotin-strept(avidin) technologies: Implications for individuals with biotin-responsive inherited metabolic disorders》 appeared in Molecular Genetics and Metabolism. The author of the article were Wolf, Barry. The article conveys some information:

A review. This article discusses about biotin interference in immunoassays and to alert the healthcare providers who care for individuals with one or more of the biotin-responsive disorders being treated with pharmacol. doses of biotin. After reading the article, we found that the author used 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5SDS of cas: 58-85-5)

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.SDS of cas: 58-85-5 And it has been used as a vitamin supplement for the growth of Bacillus species.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Recommanded Product: 58-85-5In 2019 ,《Biotin interference in immunoassay: a review for the laboratory scientist》 appeared in Annals of Clinical Biochemistry. The author of the article were Avery, Gordon. The article conveys some information:

A review. The recent FDA Biotin (Vitamin B7): Safety Communication – May Interfere with Lab Tests and A statement from the ACB Scientific Committee regarding biotin/vitamin B7 interference in immunoassays have raised into the laboratory consciousness the need to understand and to manage the issues around biotin interference with some immunoassays and to provide education and advice to health-care providers. In patients who are prescribed biotin or take biotin supplements, biotin has the potential to cause falsely low or falsely high results in immunoassays using streptavidin-biotin binding as part of the assay methodol. Streptavidin-biotin binding is used by many manufacturers; some manufacturers use it for most of their immunoassays, some for a few of their immunoassays and some manufacturers do not use this assay format at all. The direction and magnitude of interference and the concentration of biotin which affects an assay are highly variable and assay specific. There have been many papers and case reports published recently of biotin interference in immunoassay, and biotin interference is probably one of the most difficult types of inference to detect and to obviate. This review will assess the currently available information on this topic and review the steps the laboratory can take to reduce the risk of incorrect patient results being reported. In the part of experimental materials, we found many familiar compounds, such as 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5Recommanded Product: 58-85-5)

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.Recommanded Product: 58-85-5 And it has been used as a vitamin supplement for the growth of Bacillus species.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《The biotin biosynthetic pathway in Mycobacterium tuberculosis is avalidated target for the development of antibacterial agents》 was written by Bockman, Matthew R.; Mishra, Neeraj; Aldrich, Courtney C.. Product Details of 58-85-5 And the article was included in Current Medicinal Chemistry in 2020. The article conveys some information:

Mycobacterium tuberculosis, responsible for Tuberculosis (TB), remains the leading cause of mortality among infectious diseases worldwide from a single infectious agent, with an estimated 1.7 million deaths in 2016. Biotin is an essential cofactor in M. tuberculosis that is required for lipid biosynthesis and gluconeogenesis. M. tuberculosis relies on de novo biotin biosynthesis to obtain this vital cofactor since it cannot scavenge sufficient biotin from a mammalian host. The biotin biosynthetic pathway in M. tuberculosis has been well studied and rigorously genetically validated providing a solid foundation for medicinal chem. efforts. This review examines the mechanism and structure of the enzymes involved in biotin biosynthesis and ligation, summarizes the reported genetic validation studies of the pathway, and then analyzes the most promising inhibitors and natural products obtained from structure-based drug design and phenotypic screening. The results came from multiple reactions, including the reaction of 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5Product Details of 58-85-5)

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.Product Details of 58-85-5 And it has been used for blocking endogenous biotin during immunohistology procedures.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2019,Applied Microbiology and Biotechnology included an article by Le, Quan; Nguyen, Vyncent; Park, Sheldon. Application In Synthesis of 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid. The article was titled 《Recent advances in the engineering and application of streptavidin-like molecules》. The information in the text is summarized as follows:

Streptavidin (SA), and other related proteins, has been isolated from a wide range of organisms, including bacteria, fungi, frogs, fish, and birds. Although their original function is not well understood, they have found an important place in biotechnol. based on their unique ability to bind biotin mols. with high affinity and specificity. The SA-biotin interaction is robust and easy to incorporate into different designs, and as such, it is used when reliable mol. interaction is needed under poorly controlled exptl. conditions. There are continued efforts to engineer these proteins to modulate their size, valency, and affinity, since the optimum mol. properties vary depending on individual applications. This review will describe recent developments in streptavidin engineering to meet these requirements, including those that form novel oligomeric states, e.g., a monomer, have fewer functional biotin-binding sites, or bind biotin with reduced affinity. We also examine various reported applications of both natural or engineered SA constructs in cell biol., biochem., genetics, synthetic chem., cancer therapy, drug delivery, and nanotechnol. to illustrate the breadth of modern science that is advanced by the endogenous and engineered SA-biotin interactions. In the experiment, the researchers used 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5Application In Synthesis of 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid)

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.Application In Synthesis of 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid The biotin/avidin or biotin/streptavidin interaction is utilized in many labeling and purification schemes.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Controlling the nanoscale friction by layered ionic liquid films》 was written by An, Rong; Qiu, Xiuhua; Shah, Faiz Ullah; Riehemann, Kristina; Fuchs, Harald. COA of Formula: C8H15BF4N2 And the article was included in Physical Chemistry Chemical Physics in 2020. The article conveys some information:

The nanofriction coefficient of ionic liquids (ILs), 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM][BF4]) and 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]), on the surfaces of mica and graphite was investigated using at. force microscopy (AFM). A pronounced layered spatial distribution was found in the IL film formed on the solid substrates and can be divided into 3 well distinguishable regions exhibiting different phys. properties with increasing distance from the substrate. We found that the friction coefficient (μ) increases monotonically as the layering thickness decreases, no matter what the thickness of the bulk IL is. This suggests that the layering assembled IL at solid surfaces is more important than the bulk phase in determining the magnitude of the nanoscale friction. The increase in the friction coefficient as the layering thickness decreases is most likely attributed to the assembled ordered IL layers closer to the substrate surfaces having a greater activation barrier for unlocking the surfaces to allow shear. In the experimental materials used by the author, we found 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6COA of Formula: C8H15BF4N2)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. A multidisciplinary study on lonic liquids is emerging, including chemistry, materials science, chemical engineering, and environmental science. More specifically, some important fundamental viewpoints are now different from the original concepts, as insights into the nature of lonic liquids become deeper. For example, the physicochemical properties of lonic liquids are now recognized as ranging broadly from the oft quoted “nonvolatile, non-flammable, and air and water stable” to those that are distinctly volatile, flammable, and unstable. COA of Formula: C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Insights on [BMIM][BF4] and [BMIM][PF6] ionic liquids and their binary mixtures with acetone and acetonitrile》 were Trenzado, J. L.; Gutierrez, A.; Alcalde, R.; Atilhan, M.; Aparicio, S.. And the article was published in Journal of Molecular Liquids in 2019. Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate The author mentioned the following in the article:

The properties of ionic liquid plus acetone or acetonitrile mixtures were studied from the macro and microscopic levels by the measurement of relevant thermophys. properties and through mol. modeling studies. The liquid mixtures were considered in the whole composition range and analyzed in terms of possible hydrogen bonding between the ions and ions with the mol. solvents. The reported results show how the large non-ideality of these systems stands on the high affinity of acetone and acetonitrile for the imidazolium hydrogen bond donor sites, which allow competition with the corresponding anions for these sites specially but not limited to mol. solvent rich mixtures The reported results allow to quantify the relevance of hydrogen bonding for the properties of ionic liquid – mol. solvent mixtures, which can be fine-tuned through the amounts of cosolvent present in the mixture as a mechanism to control mixed fluids organization. In addition to this study using 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate, there are many other studies that have used 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate) was used in this study.

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 1965,Nature (London, United Kingdom) included an article by Burton, D. E.; Lambie, A. J.; Ludgate, J. C. L.; Newbold, G. T.; Percival, A.; Saggers, D. T.. Recommanded Product: 3671-65-6. The article was titled 《2-Trifluoromethylbenzimidazoles: a new class of herbicidal compounds》. The information in the text is summarized as follows:

The herbicidal activity of 2-trifluoromethylbenzimidazoles was studied on postemergent and preemergent peas (Pisum sativum), mustard (Sinapis alba), linseed (Linum usitatissimum), beet (Beta vulgaris), buckwheat (Fagopyrum esculentum), and barley (Hordeum vulgare); mammalian toxicity was studied in rats. The herbicidal activity of 2-trifluoromethylbenzimidazole was enhanced by 5-halo substitution, the order of activity being iodo and bromo > chloro > fluoro. 5-Cyano-2-trifluoromethylbenzimidazole, 5-nitro-2-trifluoromethylbenzimidazole, and 5-trifluoromethyl-2-trifluoromethylbenzimidazole had the same overall activity as 5-iodo-2-trifluoromethylbenzimidazole. 5 – Methyl -2 – trifluoromethylbenzimidazole, 5-methoxy-2-trifluoromethylbenzimidazole, and 5-amino-2-trifluoromethylbenzimidazole were as active as the parent compound Variation in species specificity with slight modification to structure was observed in the halogen series, where selectivity in favor of peas increased 4-fold from the 5-fluoro to the 5-iodo derivatives, the reverse occurring in the case of barley. Mammalian toxicity tended to follow the herbicidal activity with the exception that the 5-iodo and 5-bromo compounds had a lower mammalian toxicity than 5-chloro-2-trifluoromethylbenzimidazole. Compounds with good herbicidal activity had pKa values of 5-8, with the exception of 5-tert-butyl-2-trifluoromethylbenzimidazole. The preemergent activity of 2-trifluoromethylbenzimidazoles was significant but of less interest. The experimental process involved the reaction of 6-Methoxy-2-(trifluoromethyl)-1H-benzo[d]imidazole(cas: 3671-65-6Recommanded Product: 3671-65-6)

6-Methoxy-2-(trifluoromethyl)-1H-benzo[d]imidazole(cas: 3671-65-6) belongs to imidazoles.Although other azole heterocycles are ubiquitous in a wide range of biologically active natural products, imidazole rings occur predominantly in the natural amino acid histidine. Recommanded Product: 3671-65-6 In addition, imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Quality Control of 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborateIn 2020 ,《Preparation and characterization of PEBAX-5513/AgBF4/BMIMBF4 membranes for olefin/paraffin separation》 was published in Polymers (Basel, Switzerland). The article was written by Kim, So Young; Cho, Younghyun; Kang, Sang Wook. The article contains the following contents:

In this study, we investigated a poly(ether-block-amide)-5513 (PEBAX-5513)/AgBF4/ 1-butyl-3-methylimidazolium tetrafluoroborate (BMIMBF4) composite membrane, which is expected to have a high stabilizing effect on the Ag+ ions functioning as olefin carriers in the amide group. Poly(ethylene oxide) (PEO) only consists of ether regions, whereas the PEBAX-5513 copolymer contains both ether and amide regions. However, given the brittle nature of the amide, the penetration of BMIMBF4 remains challenging. The nanoparticles did not stabilize after their formation in the long-term test, thereby resulting in a poor performance compared to previous experiments using PEO as the polymer (selectivity 3; permeance 12.3 GPU). The properties of the functional groups in the polymers were assessed using Fourier transform IR spectroscopy, SEM, and thermogravimetric anal., which confirmed that the properties endowed during the production of the film using the ionic liquid can impact the performance. In the part of experimental materials, we found many familiar compounds, such as 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Quality Control of 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. Quality Control of 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

SDS of cas: 174501-65-6In 2021 ,《Mobility gradients yield rubbery surfaces on top of polymer glasses》 appeared in Nature (London, United Kingdom). The author of the article were Hao, Zhiwei; Ghanekarade, Asieh; Zhu, Ningtao; Randazzo, Katelyn; Kawaguchi, Daisuke; Tanaka, Keiji; Wang, Xinping; Simmons, David S.; Priestley, Rodney D.; Zuo, Biao. The article conveys some information:

Abstract: Many emerging materials, such as ultrastable glasses1,2 of interest for phone displays and OLED television screens, owe their properties to a gradient of enhanced mobility at the surface of glass-forming liquids The discovery of this surface mobility enhancement3-5 has reshaped our understanding of the behavior of glass formers and of how to fashion them into improved materials. In polymeric glasses, these interfacial modifications are complicated by the existence of a second length scale-the size of the polymer chain-as well as the length scale of the interfacial mobility gradient6-9. Here we present simulations, theory and time-resolved surface nano-creep experiments to reveal that this two-scale nature of glassy polymer surfaces drives the emergence of a transient rubbery, entangled-like surface behavior even in polymers comprised of short, subentangled chains. We find that this effect emerges from superposed gradients in segmental dynamics and chain conformational statistics. The lifetime of this rubbery behavior, which will have broad implications in constraining surface relaxations central to applications including tribol., adhesion, and surface healing of polymeric glasses, extends as the material is cooled. The surface layers suffer a general breakdown in time-temperature superposition (TTS), a fundamental tenet of polymer physics and rheol. This finding may require a reevaluation of strategies for the prediction of long-time properties in polymeric glasses with high interfacial areas. We expect that this interfacial transient elastomer effect and TTS breakdown should normally occur in macromol. systems ranging from nanocomposites to thin films, where interfaces dominate material properties5,10. The experimental process involved the reaction of 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6SDS of cas: 174501-65-6)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. SDS of cas: 174501-65-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem