Tag: 200-300

In 2019,Chinese Journal of Chemical Engineering included an article by Li, Jinlong; Zhu, Hong; Peng, Changjun; Liu, Honglai. COA of Formula: C8H15BF4N2. The article was titled 《Densities and viscosities for ionic liquids [BMIM][BF4] and [BMIM][Cl] and their binary mixtures at various temperatures and atmospheric pressure》. The information in the text is summarized as follows:

The d. and viscosity of 1-butyl-3-methylimidazolium tetrafluoroborate [BMIM][BF4] and 1-butyl-3-methylimidazolium chloride [BMIM][Cl] and their binary mixtures within the temperatures from 303.15 K to 323.15 K and at ambient pressure were determined in this work. The temperature dependences of d. and viscosity were satisfactorily described with the linear model and the Vogel-Tammann-Fulcher type equation, resp. The molar volume and viscosity of binary IL mixtures were predicted through ideal mixing rules showing that almost ′null′ deviations for IL mixtures were observed and their mixing was remarkably close to linear ideal behavior in the molar volumes, while comparatively large errors in viscosity occurred. Addnl., the molar volume of the investigated pure ILs and their mixtures could well be predicted by a predictive model presented by Valderrama et al. (Fluid Phase Equilib., 275 (2009) 145). In the part of experimental materials, we found many familiar compounds, such as 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6COA of Formula: C8H15BF4N2)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. A multidisciplinary study on lonic liquids is emerging, including chemistry, materials science, chemical engineering, and environmental science. More specifically, some important fundamental viewpoints are now different from the original concepts, as insights into the nature of lonic liquids become deeper. For example, the physicochemical properties of lonic liquids are now recognized as ranging broadly from the oft quoted “nonvolatile, non-flammable, and air and water stable” to those that are distinctly volatile, flammable, and unstable. COA of Formula: C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2019,Journal of cutaneous medicine and surgery included an article by John, Jason J; Lipner, Shari R. Name: 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid. The article was titled 《Consumer Perception of Biotin Supplementation.》. The information in the text is summarized as follows:

BACKGROUND: Biotin is an essential cofactor for metabolic pathways in humans. It is frequently self-prescribed by consumers and often recommended by dermatologists and primary care physicians, despite limited evidence of its effect on skin, hair, and nail disorders. A recent Food and Drug Administration (FDA) warning stated that biotin can interfere with laboratory tests. OBJECTIVES: Our objectives were to determine the perception of biotin by Amazon consumers, including perception of improvement in hair, skin, or nails with biotin supplementation and consumers’ awareness of the FDA warning on biotin. METHODS: The keyword biotin was searched on Amazon.com, and the top 1 percentile of biotin products according to average consumer review were analyzed for dosage, indications, price, quantity, warnings, number, and average score of reviews. RESULTS: From 16 biotin products analyzed, the mean review score was 4.38. The mean percentage of reviews stating that biotin helped hair, nails, and skin was 27.2%, 15.03%, and 2.8%, respectively. No biotin products mentioned the FDA warning, and only 1 reviewer referenced the warning. CONCLUSIONS: These findings suggest that biotin supplementation is prevalent and perceived as helpful despite limited evidence of improvement. The majority of biotin users were unaware that biotin interacted with laboratory testing demonstrating the need for biotin manufacturers to include a warning label about the FDA warning and for physicians to warn their patients on the risks and benefits of biotin supplementation. In the experiment, the researchers used many compounds, for example, 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5Name: 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid)

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.Name: 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid The biotin/avidin or biotin/streptavidin interaction is utilized in many labeling and purification schemes.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2019,Membranes (Basel, Switzerland) included an article by Akhmetshina, Alsu I.; Yanbikov, Nail R.; Atlaskin, Artem A.; Trubyanov, Maxim M.; Mechergui, Amal; Otvagina, Ksenia V.; Razov, Evgeny N.; Mochalova, Alla E.; Vorotyntsev, Ilya V.. Computed Properties of C8H15BF4N2. The article was titled 《Acidic gases separation from gas mixtures on the supported ionic liquid membranes providing the facilitated and solution-diffusion transport mechanisms》. The information in the text is summarized as follows:

Nowadays, the imidazolium-based ionic liquids containing acetate counter-ions are attracting much attention as both highly selective absorbents of the acidic gases and CO2 carriers in the supported ionic liquid membranes. In this regard, the investigation of the gas transport properties of such membranes may be appropriate for better understanding of various factors alecting the separation performance and the selection of the optimal operating conditions. In this work, we have tested CH4, CO2 and H2S permeability across the supported ionic liquid membranes impregnated by 1-butyl-3-methylimidazolium acetate (bmim[OAc]) with the following determination of the ideal selectivity in order to compare the facilitated transport membrane performance with the supported ionic liquid membrane (SILM) that provides solution-diffusion mechanism, namely, containing 1-butyl-3-methylimidazolium tetrafluoroborate (bmim[BF4]). Both SILMs have showed modest individual gases permeability and ideal selectivity of CO2/CH4 and H2S/CH4 separation that achieves values up to 15 and 32, resp. The elect of the feed gas mixture composition on the permeability of acidic gases and permeselectivity of the gas pair was investigated. It turned out that the permeation behavior for the bmim[OAc]-based SILM toward the binary CO2/CH4, H2S/CH4 and ternary CO2/H2S/CH4 mixtures was featured with high acidic gases selectivity due to the relatively low methane penetration through the liquid phase saturated by acidic gases. In the experiment, the researchers used 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Computed Properties of C8H15BF4N2)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. A multidisciplinary study on lonic liquids is emerging, including chemistry, materials science, chemical engineering, and environmental science. More specifically, some important fundamental viewpoints are now different from the original concepts, as insights into the nature of lonic liquids become deeper. For example, the physicochemical properties of lonic liquids are now recognized as ranging broadly from the oft quoted “nonvolatile, non-flammable, and air and water stable” to those that are distinctly volatile, flammable, and unstable. Computed Properties of C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborateIn 2021 ,《Interplay of Structure and Dynamics in Lithium/Ionic Liquid Electrolytes: Experiment and Molecular Simulation》 was published in Journal of Physical Chemistry B. The article was written by Judeinstein, Patrick; Zeghal, Mehdi; Constantin, Doru; Iojoiu, Cristina; Coasne, Benoit. The article contains the following contents:

Despite their promising use in electrochem. and electrokinetic devices, ionic-liquid-based electrolytes often exhibit complex behavior arising from a subtle interplay of their structure and dynamics. Here, the authors report a joint exptl. and mol. simulation study of such electrolytes obtained by mixing 1-Bu 3-methylimidazolium tetrafluoroborate with Li tetrafluoroborate. More in detail, experiments consisting of x-ray scattering, pulsed field gradient NMR, and complex impedance spectroscopy are analyzed in the light of mol. dynamics simulations to probe the structural, dynamical, and electrochem. properties of this ionic-liquid-based electrolyte. Li addition promotes the nanostructuration of the liquid as evidenced from the appearance of a scattering prepeak that becomes more pronounced. Microscopically, using the partial structure factors determined from mol. dynamics, this prepeak is shown to correspond to the formation of well-ordered pos./neg. charge series and also large aggregates (Lin(BF4)4-m)(4-m+n)-, which develop upon Li addition Such nanoscale ordering entails a drastic decrease in both the mol. mobility and ionic conductivity In particular, the marked association of Li+ cations with four BF4- anions and long ion pairing times, which are promoted upon Li addition, severely hinder the Li+ transport properties. In the experiment, the researchers used 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《A survey-based study of physician practices regarding biotin supplementation.》 was published in The Journal of dermatological treatment in 2020. These research results belong to Waqas, Bukhtawar; Wu, Alan; Yim, Elizabeth; Lipner, Shari R. Computed Properties of C10H16N2O3S The article mentions the following:

Biotin is an important cofactor in several metabolic pathways in humans. Biotin deficiencies are quite uncommon and there is limited data to support recommending it to treat hair, skin, and nail conditions. A 2017 FDA safety alert warned that biotin can interfere with laboratory testing resulting in incorrect diagnoses and even death. Therefore, our study objectives were to assess biotin recommendation practices and survey physician knowledge of biotin interference in routine laboratory tests. In a national survey of 149 physicians, we found that 43.9% of physicians prescribe biotin, primarily for hair and nail disorders, and 39.5% recommended other biotin-containing supplements. Most physicians answered correctly that there are no randomized studies that biotin improves dermatological conditions, and that biotin interferes with thyroid and troponin testing. Few knew of interference with b-HCG, Hepatitis serology, HIV serology and Vitamin D levels, and 19.5% were unaware of any interference. Almost half of physicians did not ask patients to discontinue biotin prior to laboratory testing. Our study shows that physicians continue to prescribe biotin despite knowledge gaps about laboratory interference, and highlights the need for increasing physician awareness of risks and benefits of recommending biotin to treat skin, hair, and nail conditions. In the experiment, the researchers used 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5Computed Properties of C10H16N2O3S)

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.Computed Properties of C10H16N2O3S And it has been used for blocking endogenous biotin during immunohistology procedures.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Assessment of risk for interference by circulating biotin in samples received for high sensitivity troponin-T, thyrotropin, and for prostate specific antigen testing by immunoassays》 was published in Clinical Laboratory (Mainz, Germany) in 2020. These research results belong to Nguyen, Khanh Q. N.; Langevin, Rachel; Fankhauser, Kimberly; Hashim, Ibrahim A.. Computed Properties of C10H16N2O3S The article mentions the following:

This study aims to examine the risk for biotin interference among our patient population. Serum and plasma leftover samples from 183 different patients were collected following completion of hs-TnT, TSH, and PSA testing. Aliquots were stored frozen at -20°C until anal. Biotin concentrations in these samples were measured using an ELISA (ALPCO, Salem, NH, USA) according to the manufacture’s protocol. Samples with biotin levels of 20 ng/mL or greater were considered as highrisk samples (HRS) for biotin interference. The overall concentrations of biotin in our patients’ samples ranged from 0.02 ng/mL to 11.38 ng/mL. The median and (range) biotin concentrations in hs-TnT, TSH, and PSA samples were 0.27 ng/mL (0.02 – 6.86 ng/mL), 0.39 ng/mL (0.08 – 11.38 ng/mL), and 0.47 ng/mL (0.09 – 7.73 ng/mL), resp. Although there was no significant difference between biotin levels in samples for TSH or PSA measurement (p – 0.85), biotin in samples for PSA and for hs-TnT and in samples for TSH and hs-TnT were significantly different (p = 0.049 and 0.089), resp. None of the samples had biotin levels greater than or equal to 20 ng/mL. Using representative samples with requests for hs-TnT, TSH, and PSA testing, where reliable performance for the selected assays at their lowest measurement range is required for clin. intervention, among our study population the risk was considered minimal as their circulating biotin levels were less than 20 ng/mL.5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5Computed Properties of C10H16N2O3S) was used in this study.

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.Computed Properties of C10H16N2O3S And it has been used for blocking endogenous biotin during immunohistology procedures.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Temperature, Composition, and Alkyl Chain-Dependent Molecular Interactions between Imidazolium-Based Ionic Liquids with N-Methylaniline and N-Ethylaniline: Experimental and Theoretical Study》 was published in Journal of Chemical & Engineering Data in 2020. These research results belong to Master, Zubin; Malek, Naved I.. Synthetic Route of C8H15BF4N2 The article mentions the following:

Ionic liquids (ILs), an alternative to conventional mol. organic solvents, have attracted the attention of the scientific community because of their tunable unique physicochem. properties. Among the tested strategies, addition of co-solvents is the most convenient choice to alter the physicochem. properties of ILs for their industrial applications. In the present article, we have measured the d. (ρ), speeds of sound (u), and refractive index (nD) for six binary mixtures of N-methylaniline (NMA) and N-ethylaniline (NEA) + BmimBF4 + HmimBF4 + OmimBF4 over the entire range of composition and at temperatures ranging from 293.15 to 323.15 K at 5 K intervals and at atm. pressure. Excess molar volume (VmE), excess molar isentropic compressibility (Ks,mE), and deviation in the refractive index (ΔφnD) on volume fraction basis were calculated from these measured thermophys. properties. Influence of temperature on the excess and deviation properties has been studied. VmE, Ks,mE, and ΔφnD were fitted to the Redlich-Kister polynomial equation, and the parameters for the binary coefficients are reported. The influence of the alkyl chain length of ILs on the thermophys. properties of the mixtures of secondary amines was studied. We have discussed the intermol. interactions between the ILs and amine mols. using well-known arguments. We further predicted the refractive indexes of the studied mixtures using various mixing rules, and the resulting values have been compared with the exptl. values through the standard deviation. Exptl. calculated excess molar volumes have been compared with the predicted values of the Prigogine-Flory-Patterson theory and the extended real association model at 298.15 K. In the experiment, the researchers used many compounds, for example, 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Synthetic Route of C8H15BF4N2)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. A multidisciplinary study on lonic liquids is emerging, including chemistry, materials science, chemical engineering, and environmental science. More specifically, some important fundamental viewpoints are now different from the original concepts, as insights into the nature of lonic liquids become deeper. For example, the physicochemical properties of lonic liquids are now recognized as ranging broadly from the oft quoted “nonvolatile, non-flammable, and air and water stable” to those that are distinctly volatile, flammable, and unstable. Synthetic Route of C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Label-free detection of exosomes using a surface plasmon resonance biosensor》 were Sina, Abu Ali Ibn; Vaidyanathan, Ramanathan; Wuethrich, Alain; Carrascosa, Laura G.; Trau, Matt. And the article was published in Analytical and Bioanalytical Chemistry in 2019. Quality Control of 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid The author mentioned the following in the article:

The development of a sensitive and specific detection platform for exosomes is highly desirable as they are believed to transmit vital tumor-specific information (mRNAs, microRNAs, and proteins) to remote cells for secondary metastasis. Herein, the authors report a simple method for the real-time and label-free detection of clin. relevant exosomes using a surface plasmon resonance (SPR) biosensor. The authors’ method shows high specificity in detecting BT474 breast cancer cell-derived exosomes particularly from complex biol. samples (e.g. exosome spiked in serum). This approach exhibits high sensitivity by detecting as low as 8280 exosomes/μL which may potentially be suitable for clin. anal. The authors believe that this label-free and real-time method along with the high specificity and sensitivity may potentially be useful for clin. settings. In addition to this study using 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid, there are many other studies that have used 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5Quality Control of 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid) was used in this study.

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.Quality Control of 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid And it has been used for blocking endogenous biotin during immunohistology procedures.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Molecular dynamics simulation of imidazolium CnMIM-BF4 ionic liquids using a coarse grained force-field》 was written by Fajardo, Oscar Y.; Di Lecce, Silvia; Bresme, Fernando. Electric Literature of C8H15BF4N2 And the article was included in Physical Chemistry Chemical Physics in 2020. The article conveys some information:

Ionic liquids feature thermophys. properties that are of interest in solvents, energy storage materials and tunable lubrication applications. Here we use new Coarse Grained (CG) models to investigate the structure, dynamics and interfacial properties of the [C2-8MIM][BF4] family of ionic liquids (ILs). The simulated equation of state and diffusion coefficients are in good agreement with exptl. data and with all-atom force-fields. We quantify the nano-structure and liquid-vapor interfacial properties of the ILs as a function of the size of the imidazolium cation. The computational efficiency of the CG models enables the simulation of very long time scales (100’s of nanoseconds), which are needed to resolve the dynamic and interfacial properties of ILs containing cations with long aliphatic chains. For [C>4MIM] [BF4] the break in symmetry associated to the liquid-vapor interface induces nanostructuring of polar and non-polar domains in the direction perpendicular to the interface plane, with the inhomogeneous regions penetrating deep inside the bulk liquid, typically 5 nm for C8MIM cations. In the experiment, the researchers used 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Electric Literature of C8H15BF4N2)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. Electric Literature of C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Distance Angle Descriptors of the Interionic and Ion-Solvent Interactions in Imidazolium-Based Ionic Liquid Mixtures with Aprotic Solvents: A Molecular Dynamics Simulation Study》 were Koverga, Volodymyr A.; Smortsova, Yevheniia; Miannay, Francois Alexandre; Kalugin, Oleg N.; Takamuku, Toshiyuki; Jedlovszky, Pal; Marekha, Bogdan; Cordeiro, M. Natalia D. S.; Idrissi, Abdenacer. And the article was published in Journal of Physical Chemistry B in 2019. HPLC of Formula: 174501-65-6 The author mentioned the following in the article:

The aim of this paper is to quantify the changes of the interionic and ion-solvent interactions in mixtures of imidazolium-based ionic liquids, consisting tetrafluoroborat, hexafluorophosphate, trifluoromethylsulfonate, or bis(trifluoromethanesulfonyl)imide anions, and polar aprotic mol. solvents, such as acetonitrile (AN), γ-butyrolactone, and propylene carbonate. For this purpose, we calculate, using the nearest neighbor approach, the average distance between the imidazolium ring H atom in positions 2, 4 and 5 (H2,4,5) and the nearest high electronegativity atom of the solvent or anion (X) as distance descriptors, and the mean angle formed by the C2,4,5 H2,4,5 bond ant the H2,4,5… X axis around the H2,4,5 atom as angular descriptors of the cation-anion and cation-solvent interactions around the ring C H groups. The behavior of these descriptors as a function of the ionic liquid mole fraction is analyzed in detail. The obtained results show that the extent of the change of these descriptors with respect to their values in the neat ionic liquid depends both on the nature of the anion and on the mixture composition Thus, in the case of the mixtures of the mol. solvents with BmimBF4 and BmimTFO, a small change of the distance and a drastic increase of the angular descriptor corresponding to the cation-anion interactions is observed with decreasing mole fraction of the ionic liquid, indicating that the anion moves from the above/below position (with respect to the imidazolium ring plane) to a position that is nearly linearly aligned with the C2-H2 bond, and hinders the possible interaction between the C2-H2 group and the solvent mols. On the other hand, in the case of mixtures of BmimTFSI and BmimPF6 with the mol. solvents, both the observed increase of the distance descriptor and the slight change of the angular descriptor with decreasing ionic liquid mole fraction are compatible with the direct interactions of the solvent with the C2-H2 group. The behavior of these descriptors is correlated with the exptl. observed 1H chem. shift of the C2-H2 group and red shift of the C2 H2 vibrational mode, particularly at low ionic liquid mole fractions. The present results are thus of great help in interpreting these exptl. observations. In the part of experimental materials, we found many familiar compounds, such as 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6HPLC of Formula: 174501-65-6)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. HPLC of Formula: 174501-65-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem