Tag: M.W=0-100

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 822-55-9, Name is 4-(Hydroxymethyl)imidazole, SMILES is OCC1=CNC=N1, belongs to imidazoles-derivatives compound. In a document, author is Tasdemir, Volkan, introduce the new discover, Safety of 4-(Hydroxymethyl)imidazole.

Copper-Catalyzed Synthesis of Fused Imidazopyrazine N-Oxide Skeletons

N-Propargyl-2-aroylimidazoles synthesized and converted into the corresponding ketoximes. Under various conditions, several mono- and diketoxime imidazole derivatives were formed by converting the carbonyl or carbonyl and propargyl groups into oxime groups. N-Propargyl monooxime imidazole derivatives were cyclized by treatment with CuI to give various imidazopyrazine N-oxides. Several copper salts, such as CuOAc, CuSO (4) , and CuOTf, formed the same cyclization product. This cyclization reaction occurred only in the presence of Cu(I) or Cu(II) salts; other transition metals such as Au, Ag, In, and Fe did not yield cyclic products. The nucleus-independent chemical shift method was used to calculate the aromaticity of the bicyclic rings.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 822-55-9 is helpful to your research. Safety of 4-(Hydroxymethyl)imidazole.

Application of 1072-63-5, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 1072-63-5, Name is 1-Vinyl-1H-imidazole, SMILES is C=CN1C=CN=C1, belongs to imidazoles-derivatives compound. In a article, author is Srivastava, A. K., introduce new discover of the category.

Quantitative structure activity relationship (QSAR) studies on a series of imidazole derivatives as novel ORL1 receptor antagonists

QSAR studies were performed on a series of imidazole derivatives as novel Orl1 receptor antagonists. Imidazole derivatives have been analyzed in relation to their physicochemical and molecular properties. The activities of the compounds were found to be significantly correlated with the physicochemical parameters such as density (D), surface tension (St), index of refraction (Ior), balaban index (J) and partition coefficient (Log P). It was found that the presence of group at R-1 position was conducive for the inhibitory activity. The results are critically discussed on the basis of regression data and cross validation techniques. Poglani factor Q and the results of LOO (leave one out) method confirms the reliability and predictability of the proposed models. (C) 2011 King Saud University. Production and hosting by Elsevier B.V. All rights reserved.

Application of 1072-63-5, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 1072-63-5.

693-98-1, Name is 2-Methyl-1H-imidazole, molecular formula is C4H6N2, Product Details of 693-98-1, belongs to imidazoles-derivatives compound, is a common compound. In a patnet, author is Mushik, OV, once mentioned the new application about 693-98-1.

Electrochemical and analytical properties of solid-contact ion-selective electrodes reversible to the imidazole derivatives clotrimazole and bifonazole

Solid-contact ion-selective electrodes reversible to imidazole derivatives [Clotrimazole {diphenyl(2-chlorophenyl)-1-imidazolylmethane} and Bifonazole {phenyl-(4-diphenyl)-1-imidazolylmethane}] were developed. The electrochemical and analytical properties of electrodes with polyvinyl chloride and cellulose hydrate plasticized membranes supported on copper, platinum, graphite, or Ag/AgCl current conductors were presented. Rapid procedures for the direct potentiometric determination of Clotrimazole and Bifonazole in ointments are developed.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 693-98-1 help many people in the next few years. Product Details of 693-98-1.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 1072-62-4, Name is 2-Ethyl-1H-imidazole, formurla is C5H8N2. In a document, author is Matsumoto, Shoji, introducing its new discovery. Product Details of 1072-62-4.

SYNTHESIS AND OPTICAL PROPERTIES OF 2,2 ‘-BIIMIDAZOLE AND BENZO[d]IMIDAZOLE DERIVATIVES: CHANGING pi-CONJUGATION BY PHOTOEXCITATION

1,1′,5,5′-Tetraaryl-2,2′-biimidazole and benzo [d] imidazole derivatives were synthesized. Symmetrical and unsymmetrical benzo[d]imidazole derivatives could be obtained by the Pd-catalyzed coupling reaction between 2-iodo-benzo[d]imidazole and the corresponding (benzo)imidazole anion. Hypsochromic shifts in absorption and fluorescence spectra of 1,1′,5,5′-tetraaryl-2,2’-biazole were observed by switching pyrrole rings for imidazole and benzo[d]imidazole rings, resulting in compounds with various Stokes shifts. Based on the (TD)DFT calculation, it was reasoned that changing the conformation of each single bond from a twisted to planar structure by photoexcitation led to larger Stokes shifts.

If you are hungry for even more, make sure to check my other article about 1072-62-4, Product Details of 1072-62-4.

Electric Literature of 616-47-7, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 616-47-7, Name is 1-Methyl-1H-imidazole, SMILES is CN1C=CN=C1, belongs to imidazoles-derivatives compound. In a article, author is Konishi, Hideyuki, introduce new discover of the category.

Remarkable Improvement Achieved by Imidazole Derivatives in Ruthenium-Catalyzed Hydroesterification of Alkenes Using Formates

Imidazole derivatives are revealed to be effective ligands in the Ru-catalyzed hydroesterification of alkenes using formates, affording one-carbon-elongated esters in high yields. Further, intramolecular hydroesterification was successfully performed to give lactones for the first time. Imidazole derivatives can contribute to promote the reaction as well as to suppress the undesired decarbonylation of formate. Toxic CO gas, a directing group, and large excess alkenes are not required.

Electric Literature of 616-47-7, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 616-47-7.

Electric Literature of 1072-63-5, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 1072-63-5, Name is 1-Vinyl-1H-imidazole, SMILES is C=CN1C=CN=C1, belongs to imidazoles-derivatives compound. In a article, author is Le Borgne, Marc, introduce new discover of the category.

Synthesis and biological evaluation of 3-(azolylmethyl)-1H-indoles and 3-(alpha-azolylbenzyl)-1H-indoles as selective aromatase inhibitors

This present study identifies a number of azolyl-substituted indoles as potent inhibitors of aromatase. In the sub-series of 3-(azolylmethyl)-1H-indoles, four imidazole derivatives and their triazole analogues were tested. Imidazole derivatives 11 and 14 in which the benzyl moiety was substituted by 2-chloro and 4-cyano groups, respectively, were the most active, with IC50 values ranging between 0.054 and 0.050 mu M. In the other sub-series, eight 3-(alpha-azolylbenzyl)-1H-indoles were prepared and tested. Compound 30, the N-ethyl imidazole derivative, proved to be an aromatase inhibitor, showing an IC50 value of 0.052 mu M. All target compounds were further evaluated against 17 alpha-hydroxylase/C17,20-lyase to determine their selectivity profile.

Electric Literature of 1072-63-5, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 1072-63-5.

Synthetic Route of 1072-62-4, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 1072-62-4, Name is 2-Ethyl-1H-imidazole, SMILES is CCC1=NC=CN1, belongs to imidazoles-derivatives compound. In a article, author is Zhao, XJ, introduce new discover of the category.

Conformation study on recognition of imidazole derivatives by chiral amino acids linked porphyrins

Chiral recognition is an attractive subject in the area of host-guest chemistry. Conformation study is performed to understand chiral recognition of zinc(II) porphyrin with imidazole derivatives on a molecular level. The molecular recognition of three novel chiral zinc porphyrin(1-3) with four types of imidazole derivatives was studied. The conformation searching of this host-guest system was studied by using simulated annealing method on the basis of Tripos force field. The different minimal energy conformation of imidazole combind with porphyrin was studied. The quantum chemistry calculation was performed to calculate the single-point energies of the host-guest system. The minimal energy conformation of ZnT(o-BocAla)APP (3)-Im showed that Im attaching from the singleside chain of the host had the reasonable configuration than that from the three-side chain. The former also had the lower energy than the latter. And the quantum chemistry calculation results of orbital energy, DeltaE(L-H), and atomic net charge revealed the same way. The results illumate that combination oriention of the host-guest system is the single chain of the hosts.

Synthetic Route of 1072-62-4, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 1072-62-4 is helpful to your research.

Electric Literature of 693-98-1, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 693-98-1, Name is 2-Methyl-1H-imidazole, SMILES is CC1=NC=CN1, belongs to imidazoles-derivatives compound. In a article, author is Zampieri, Daniele, introduce new discover of the category.

Antifungal and antimycobacterial activity of 1-(3,5-diaryl-4,5dihydro-1H-pyrazol-4-yl)-1H-imidazole derivatives

1-(3,5- Diaryl-4,5-dihydro-1H-pyrazol-4-yl)-1H-imidazole derivatives were synthesized and tested for their in vitro antifungal and antimycobacterial activities. These imidazole derivatives showed an excellent antifungal activity against a clinical strain of Candida albicans and an interesting antitubercular activity against Mycobacterium tuberculosis H(37)Rv reference strain. (c) 2008 Elsevier Ltd. All rights reserved.

Electric Literature of 693-98-1, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 693-98-1.

In an article, author is Kucukbay, H, once mentioned the application of 288-32-4, COA of Formula: C3H4N2, Name is 1H-Imidazole, molecular formula is C3H4N2, molecular weight is 68.0773, MDL number is MFCD00005183, category is imidazoles-derivatives. Now introduce a scientific discovery about this category.

Synthesis and antimicrobial activity of substituted benzimidazole, benzothiazole and imidazole derivatives

New benzimidazole, benzothiazole and imidazole derivatives were synthesized by reacting electron-rich olefins (5, 23 and 29) with appropriate reagents The compounds synthesized were identified by H-1, C-13-NMR, FT-IR and mass spectroscopic techniques and micro analysis. All new and related compounds were evaluated for their in vitro antimicrobial activity against different bacteria. The compounds 17, 18, 19, 20, 21, 22 and 24 were found very effective to inhibit the growth of Enterococcus faecalis (ATCC 29212) and Staphylococcus aureus (ATCC 29213) at minimum inhibitory concentrations (MICs) of 25, 25, 12.5, 50, 25, 50 and 50 mu g/ml, respectively. The compounds 4, 10a, 10c, 16, 25, 26 and 31 were significantly effective against Enterococcus faecalis (ATCC 29212) and Staphylococcus aureus (ATCC 29213) with MIC values of 100-200 mu g/ml. None of the compounds proved to be effective against Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853) in the concentrations studied.

If you are interested in 288-32-4, you can contact me at any time and look forward to more communication. COA of Formula: C3H4N2.

Reference of 822-55-9, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 822-55-9, Name is 4-(Hydroxymethyl)imidazole, SMILES is OCC1=CNC=N1, belongs to imidazoles-derivatives compound. In a article, author is Vichier-Guerre, Sophie, introduce new discover of the category.

A convenient synthesis of 4(5)-(hetero)aryl-1H-imidazoles via microwave-assisted Suzuki-Miyaura cross-coupling reaction

A simple and rapid access to a variety of 4(5)-arylated imidazoles via palladium-catalyzed Suzuki-Miyaura cross-coupling reaction is described. Coupling parameters were screened for efficient C-4 arylation of N-unprotected 4-iodoimidazole with a broad range of boronic acids under microwave irradiation. Twenty-one imidazole derivatives were synthesized in modest to excellent yields in short reaction times. (C) 2014 Elsevier Ltd. All rights reserved.

Reference of 822-55-9, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 822-55-9.