Tag: M.W=150-200

Wang, Yuanyuan published the artcileGreen fabrication of an ionic liquid-activated lignocellulose flame-retardant composite, Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, the publication is Industrial Crops and Products (2022), 114602, database is CAplus.

A flame-retardant lignocellulose composite was fabricated via ionic liquid activation assisted by hot-pressing. To obtain a dilated, isolated surface, lignocellulose was pretreated with an ionic liquid After modification with an ionic liquid, micro/nanofibrils appeared on the surface of lignocellulose. Crosslinking between micro/nanofibrils was beneficial for the deposition of inorganic particles. Ammonium polyphosphate and aluminum hydroxide particles were deposited on the surface of lignocellulose via hydrogen bonding and van der waals adsorption, forming a flame-retardant layer. The ionic liquid-activated flame-retardant lignocellulose composite exhibited better flame retardancy and higher mech. strength than those of pure lignocellulose. Compared to those of pure lignocellulose, the heat release rate (HRR), total heat release (THR) and total smoke production (TSP) of lignocellulose-based ammonium polyphosphate/aluminum hydroxide (LPA) composites decreased by 78.5%, 35.71% and 88.24%, resp. The LPA composites had a mech. strength of 48.5 MPa, which was 33.99% higher than that of pure lignocellulose. This method provides a new approach for lignocellulose-based flame-retardant materials.

Industrial Crops and Products published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C13H10F2, Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Hu, Kaibo published the artcileRemoval of aluminum to obtain high purity gadolinium with pyridinium-based ionic liquids, Formula: C8H15ClN2, the publication is Hydrometallurgy (2022), 105930, database is CAplus.

As an associated element, aluminum (Al(III)) has a neg. effect on the purity of rare earth gadolinium (Gd(III)). Three pyridinium-based ionic liquids ([(CH₂)nCOOHpyr][NTf₂], n = 3, 5, 7) were proposed as the solvent in liquid-liquid extraction for separation of the Al(III) impurity from Gd(III) in this study. The effect of pH value of the aqueous phase, diluent type, extraction time and temperature on the extraction separation of Al³⁺ from GdCl₃ solution were investigated systemically. The results show that the separation factor β of Al(III)/Gd(III) is up to 340 by adjusting the pH value of the aqueous phase which is higher than the values of other reported systems, and the removal efficiency of Al(III) could reach 97.1%, with the recovery efficiency of Gd(III) of 85.6% through one-time extraction using a mixture of ionic liquids[(CH₂)₇COOHpyr][NTf₂]-[C₄mim][NTf₂] as the extractant. The slope anal. and IR spectroscopic characterization indicated that the extraction mechanism of Al(III) by the [(CH₂)₇COOHpyr][NTf₂]-[C₄mim][NTf₂] system follows the cation exchange mechanism. After the extraction, 0.08 mol/L hydrochloric acid aqueous solution was used to strip Al(III) from the ionic liquid phase, and complete recovery of Al(III) could be realized. The extraction efficiency of the [(CH₂)₇COOHpyr][NTf₂]-[C₄mim][NTf₂] system for separation of Al(III) is still more than 97.8% after recycling for 8 cycles.

Hydrometallurgy published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Formula: C8H15ClN2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Zhang, C. published the artcileEfficient synthesis and biological activity of novel indole derivatives as VEGFR-2 tyrosine kinase inhibitors, SDS of cas: 4760-35-4, the publication is Russian Journal of General Chemistry (2017), 87(12), 3006-3016, database is CAplus.

Series of novel indole derivatives, e.g. I were synthesized as potent inhibitors for the vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase. Among those, compound I demonstrated the highest growth inhibition rate of 66.7% against the VEGFR-2 tyrosine kinase at 10 μM which indicates that indole-benzothiazole might be the favorable structure. The binding mode of compound I with VEGFR-2 tyrosine kinase was evaluated by mol. docking.

Russian Journal of General Chemistry published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C3H9ClOS, SDS of cas: 4760-35-4.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Guo, Chao published the artcileThermodynamic and economic comparison of extractive distillation sequences for separating methanol/dimethyl carbonate/water azeotropic mixtures, SDS of cas: 79917-90-1, the publication is Separation and Purification Technology (2022), 282(Part_B), 120150, database is CAplus.

The separation of di-Me carbonate (DMC)/methanol/water azeotropic mixtures has been a hot topic in the study of DMC synthesis process. In this work, the efficient organic solvent Me salicylate, ionic liquids (ILs) 1-butyl-3-methylimidazolium chloride ([BMIM][Cl]), or 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([BMIM][NTf₂]) was employed to break azeotropic mixtures Interaction mechanisms between DMC/methanol/water and entrainers were revealed by sigma-profile. Energy and economic comparison of two alternative separation sequences including pre-separation integration with extractive-heterogeneous distillation and direct extractive distillation processes were investigated. The average relative deviations (ARD) were used to check the reliability of the NRTL model. The effect of high viscosity fluid on the mass transfer was analyzed from the perspective of the overall efficiency of column. For [BMIM][Cl], the separation mechanism is the formation of H-bond between [BMIM][Cl] and methanol/water. Direct extractive distillation process is superior to pre-separation integration with extractive-heterogeneous distillation process in terms of steam consumption, capital cost, mass transfer efficiency and total annual cost (TAC), and [BMIM][Cl]-based direct extractive distillation process is the best. This work provides a green and efficient separation route for replacing organic solvent-based process.

Separation and Purification Technology published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, SDS of cas: 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Ren, Fei published the artcileGreen synthesis of acetylated maize starch in different imidazolium carboxylate and choline carboxylate ionic liquids, Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, the publication is Carbohydrate Polymers (2022), 119353, database is CAplus and MEDLINE.

This work demonstrates that acetylated maize starches (AMS) with varied degree of substitution (DS, 0.26-2.63) was synthesized in ionic liquids (ILs) (imidazolium chloride, imidazolium carboxylate and choline carboxylate) at 85°C without catalyst. The DS of AMS and reaction efficiency increased with decreasing alkyl chain length of cations or anions, while decreased as the choline cation replaced the imidazolium cation and the chloride anion replaced the acetate anion. The AMS synthesized in imidazolium-based ILs exhibited much higher hydrophobicity and thermal stability than the native starch. Rheol. properties of ILs and ATR-FTIR anal. of acetic anhydride/ILs mixtures indicated that a shorter alkyl side chain or the combination of an imidazolium cation and an acetate anion gave ILs lower viscosities and weaker interactions between acetic anhydride mols., which favored the acetylation of starch. These findings provide insights into the design of green processes to modify starch and the application of acetylated starch.

Carbohydrate Polymers published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Wang, Ling-Yun published the artcileButterfly and chair clusters using N,O-chelating ligands: A combined crystallographic and mass spectrometric study, Quality Control of 7467-35-8, the publication is Applied Organometallic Chemistry (2020), 34(5), e5533, database is CAplus.

The organic ligand (1-methyl-1H-benzo[d]imidazol-2-yl)methanol (HL¹) was used to react with Cu(ClO₄)₂·6H₂O and triethylamine at 80°C to afford the complex [Cu₄(L¹)₆]·(ClO₄)₂·CH₃CN (1). Every four-coordinated Cu(II) ion is surrounded with NO₃ coordinated environment, and every five-coordinated Cu(II) ion is surrounded with N₂O₃ coordinated environment. Changing the metal salt to Zn(NO₃)₂·6H₂O, and after adding CH₃COONa, afforded the complex [Zn₄(L¹)₄(NO₃)₂(CH₃COO)₂] (2), in which every five-coordinated Zn(II) ion is surrounded with NO₄ coordinated environment. High-resolution electrospray ionization mass spectrometry results revealed that complex 1 broke into the most stable fragment [Cu₂(L¹)₃]⁺, and it also can assemble high nuclear peaks in solution For complex 2, it was found that the complex exhibited different component distribution in solution Not only were there substitutions between coordinated anions, but the high nuclear peaks could also be detected.

Applied Organometallic Chemistry published new progress about 7467-35-8. 7467-35-8 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Alcohol, name is (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, and the molecular formula is C8H11BO2, Quality Control of 7467-35-8.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Wang, Liling published the artcileExtraction and Determination of Protein from Edible Oil Using Aqueous Biphasic Systems of Ionic Liquids and Salts, Application In Synthesis of 79917-90-1, the publication is Food and Bioprocess Technology (2022), 15(1), 190-202, database is CAplus.

This study aimed to develop the extraction method of protein from edible oil for rapid detection. Firstly, aqueous biphasic systems (ABS) based on six hydrophilic ionic liquids (ILs) and three salts were developed and the phase diagram was drawn by turbidimetric point method. The binodal curves were fitted to the Merchuk equation. On this basis, the ABS composed of IL and salt were applied to extract protein from edible oil. The type of IL or salt, IL concentration, salt concentration, oil mass, extraction pH, and temperature on the extraction efficiency of protein from oil were investigated. The results showed that the optimum conditions for the extraction of protein from edible oil with ABS were as follows: 50% (w/v) K3PO4, 20% (w/v) [Bmim]Cl at 35°C, and pH 9.0. Under the optimal conditions, the protein extraction efficiency was almost 100%. Also, the extraction mechanism was studied and the main driving factors of protein extraction may be the hydrophobicity, electrostatic interaction, and salting-out between mols. Finally, the method was used to detect the com. edible oils from different sources. The results showed that the ABS could also be used to extract protein from other edible oils. In conclusion, the IL-based ABS method is simple and rapid for protein extraction from edible oil, and will highlight novel possibilities in the large-scale separation and purification of protein from oily solution

Food and Bioprocess Technology published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C38H74Cl2N2O4, Application In Synthesis of 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Li, Na published the artcileThe activity and molecular interaction of lysozyme in adding four ionic liquids aqueous solutions, Computed Properties of 79917-90-1, the publication is Journal of Molecular Liquids (2022), 118788, database is CAplus.

In this work, four hydrophilic ionic liquids (ILs, 1-butyl-3-methylimidazolium tetrafluoroborate ([C₄mim]BF₄), 1-butyl-3-methylimidazolium chloride ([C₄mim]Cl), 1-butyl-3-methylimidazolium bromide ([C₄mim]Br) and 1,3-dimethylimidazolium iodide ([dmim]I)) were selected to probe their effect on lysozyme activity and the mol. interaction in aqueous solutions Specifically, the effects of pH and concentration of ILs on lysozyme activity were investigated by using the spectrophotometric turbidity assay. The results demonstrated that the effect of ILs on lysozyme activity depended on the concentration of ILs. Fixing the pH at 6.85, lysozyme activity rose firstly and then reduced with the increase of concentration of four ILs, reaching the maximum at 75 mM. The UV-Vis spectra illustrated that the interaction between ILs and lysozyme was weak. The results of emission and synchronous fluorescence spectra indicated that ILs had a quenching effect on the fluorescence of lysozyme, and the quenching effect increased with the increasing concentration of ILs. Meanwhile, the fluorescent quenching mechanism of ILs on lysozyme was dynamic quenching, and ILs had significant effects on the tryptophan (Trp) residues Trp62 or Trp108 at the active site of lysozyme, which suggested that effects of ILs on lysozyme activity could be attributed to the conformational changes of lysozyme triggered by changes in the microenvironment surrounding Trp62 or Trp108.

Journal of Molecular Liquids published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Computed Properties of 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Ma, Xiong-Feng published the artcileLigand Effect on the Single-Molecule Magnetism of Tetranuclear Co(II) Cubane, SDS of cas: 7467-35-8, the publication is Inorganic Chemistry (2017), 56(24), 15178-15186, database is CAplus and MEDLINE.

A clear dependence on the ligand has been observed for the magnetic properties of a closely related series of Co(II) cubane structures, viz. [Co₄(mbm or bm)₄(ROH)₄Br₄] (1-MeOH, 1-EtOH, 2-MeOH, and 2-EtOH, where 1 = [Co₄(mbm)₄Br₄], 2 = [Co₄(bm)₄Br₄], bm = (1H-benzo[d]imidazol-2-yl)methanolate. and mbm = 1-Me-bm.). The [Co₄(OR)₄] cubane core consists of an octahedral Co^II center chelated by the alkoxide oxygen and imidazole nitrogen atoms from monoanionic bm or mbm and coordinated by methanol/alc. and bromine. Interestingly, electrospray ionization mass spectrometry (ESI-MS) indicates that 1-MeOH and 2-MeOH are unstable in methanol and transformed to the butterfly [Co₄L₆]²⁺ but that 1-EtOH and 2-EtOH are stable in ethanol. Their magnetic susceptibilities suggest ferromagnetic coupling between the nearest cobalt centers to give a theor. S = 4 × 3/2 ground state with considerable magneto-crystalline behavior. The packing and intermol. interactions appear to influence the geometry of the cubes and thus the anisotropy of cobalt, which leads to different blocking temperatures (T_B). Consequently, the compounds with mbm, 1-MeOH and 1-EtOH, exhibit T_B > 2 K as shown by the relaxation of magnetization in zero applied dc field where the barriers U_eff/k_B are resp. 27 and 21 K and relaxation times are τ₀ = 1.3 × 10^-9 and 9.7 × 10^-9 s. However, the compounds with bm, 2-MeOH and 2-EtOH, remain paramagnetic above 2 K and do not show nonlinear response of the ac susceptibilities. These findings reaffirm the subtle dependence of single-mol. magnetism on coordination geometry and intermol. interaction.

Inorganic Chemistry published new progress about 7467-35-8. 7467-35-8 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Alcohol, name is (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, and the molecular formula is C9H10N2O, SDS of cas: 7467-35-8.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Hassan, Mujtaba published the artcileBenzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimization, Computed Properties of 4760-35-4, the publication is European Journal of Medicinal Chemistry (2021), 113664, database is CAplus and MEDLINE.

We have obtained the X-ray crystal structure of the galectin-8 N-terminal domain (galectin-8N) with a previously reported quinoline-galactoside ligand at a resolution of 1.6 Å. Based on this X-ray structure, a collection of galactosides derivatized at O3 with triazole, benzimidazole, benzothiazole, and benzoxazole moieties were designed and synthesized. This led to the discovery of a 3-O-(N-methylbenzimidazolylmethyl)-galactoside with a K_d of 1.8μM for galectin-8N, the most potent selective synthetic galectin-8N ligand to date. Mol. dynamics simulations showed that benzimidazole-galactoside derivatives bind the non-conserved amino acid Gln47, accounting for the higher selectivity for galectin-8N. Galectin-8 is a carbohydrate-binding protein that plays a key role in pathol. lymphangiogenesis, modulation of the immune system, and autophagy. Thus, the benzimidazole-derivatized galactosides, e.g. I, represent promising compounds for studies of the pathol. implications of galectin-8, as well as a starting point for the development of antitumor and antiinflammatory therapeutics targeting galectin-8.

European Journal of Medicinal Chemistry published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Computed Properties of 4760-35-4.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem