Tag: M.W=150-200

Srinivas, K. published the artcileTriethanolamine: a resourceful, reusable, eco-friendly, reaction medium for phase transfer catalyst – free synthesis of 1-(arylsulfonyl)aryl/heterylmethanes, Formula: C9H9ClN2, the publication is Chemical Science Transactions (2014), 3(1), 375-381, 7 pp., database is CAplus.

Synthesis of sulfone derivatives I (R = X = H, CH₃; Ar = 4-CH₃C₆H₄, C₆H₅) from reaction of arylmethyl/heteryl Me chloride with aryl sulfinate sodium salt NaO-S(O)-Ar at room temperature as the eco-friendly solvent in good to excellent yields.

Chemical Science Transactions published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C30H32ClN7O2, Formula: C9H9ClN2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Mitra, Mainak published the artcileHighly enantioselective epoxidation of olefins by H₂O₂ catalyzed by a non-heme Fe(II) catalyst of a chiral tetradentate ligand, HPLC of Formula: 4760-35-4, the publication is Dalton Transactions (2019), 48(18), 6123-6131, database is CAplus and MEDLINE.

The chiral tetradentate N4-donor ligand, 1-methyl-2-({(S)-2-[(S)-1-(1-methylbenzimidazol-2-yl Me)pyrrolidin-2-yl]pyrrolidin-1-yl}methyl)benzimidazole (S,S-^PDBzL), based on a chiral dipyrrolidine backbone, was synthesized and its corresponding Fe(II) complex was prepared and characterized. The x-ray structure of the complex reveals that the Fe(II) ion is in a distorted octahedral coordination environment with two cis-oriented coordination sites occupied by (labile) triflate anions. The ability of the iron complex to catalyze asym. epoxidation reactions of olefins with H₂O₂ was studied, using 2-cyclohexen-1-one, 2-cyclopenten-1-one, cis-β-methylstyrene, isophorone, chalcones and tetralones as substrates. Different carboxylic acids were used as additives to enhance yields and enantioselectivities, and 2-ethylhexanoic acid gave the best results. The catalysis results indicate that the Fe(II) complex is capable of effecting comparatively high enantioselectivities (>80%) in the epoxidation reactions.

Dalton Transactions published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, HPLC of Formula: 4760-35-4.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Sundberg, Richard J. published the artcilePreparation of 2-aryl- and 2-(aryloxymethyl)imidazo[1,2-a]pyridines and related compounds, COA of Formula: C9H9ClN2, the publication is Journal of Heterocyclic Chemistry (1988), 25(1), 129-37, database is CAplus.

A series of arylimidazopyridines I (R = H, R¹ = H, 6-Me, 7-Me, 6-NO₂, 6-Cl, 6-iodo, 6-OMe, 6-SEt, 6-SPr; R² = Br, NO₂) were prepared by the cyclocondensation of 2-aminopyridines with 4-R²C₆H₄COCH₂Br (II). I (R = H, R¹ = 6-NHAc, 6-SOEt, 6-SO₂Et, 6-cyano- 6-CHO, R² = NHAc, NHSO₂Me, NHSO₂Ph, cyano, CHO, CO₂Me, CONH₂, CSNH₂; R = Br, cyano, CHO, R¹ = H, R² = Me, Br, NO₂) were also prepared Imidazolthiazoles III and imidazopyrimidines IV (R² = NO₂, NHAc, iodo, cyano, CHO) were prepared by the reactions of 2-aminothiazoles and 2-aminopyrimidine resp. with II (R² = Br, NO₂, iodo). Various other heterocyclic compounds, e.g., 4-R³CH₂OC₆H₄CHO (R³ = 1-methylimidezol-2-yl, 2-pyridyl, 3-pyridyl, 4-pyridyl, 4-thiazolyl, etc.), were prepared by condensation reactions.

Journal of Heterocyclic Chemistry published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C23H20BN, COA of Formula: C9H9ClN2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Henriques, Ruan R. published the artcileDual Role of Magnetic Ionic Liquids as Curing Agents of Epoxy Resin and Microwave-Absorbing Additives, Synthetic Route of 79917-90-1, the publication is ACS Applied Polymer Materials (2022), 4(2), 1207-1217, database is CAplus.

The dual role of phosphonium- and imidazolium-based ionic liquids (ILs) combined with FeCl₄ counter anions as hardeners for epoxy resin (ER) and additives for improving the microwave-absorbing properties was studied. The influence of the chem. nature of the cation on the curing process of ER was evaluated by rheometric and differential scanning calorimetry (DSC) anal. No significant curing process was observed for the ER-based systems until 7 days of storage at room temperature DSC anal. under the dynamic mode was carried out at different heating rates to evaluate the best curing protocol and the kinetic parameters. Phosphonium-based ILs promoted faster curing rate and lower activation energy of the epoxy system, higher cross-link d. observed by dynamic mech. anal., and better thermal stability. Moreover, ER cured with phosphonium ILs presented good microwave-absorbing properties, with min. reflection loss values of -13.5 dB (at 9.5 GHz) and -11.5 dB (at 14.5 GHz), corresponding to more than 90% of electromagnetic attenuation. ER cured with these magnetic ILs can be used as promising microwave-absorbing materials in both X-band (8-12 GHz) and Ku-band (12-18 GHz).

ACS Applied Polymer Materials published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Synthetic Route of 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Flosi, William J. published the artcileDiscovery of imidazolidine-2,4-dione-linked HIV protease inhibitors with activity against lopinavir-resistant mutant HIV, Computed Properties of 4760-35-4, the publication is Bioorganic & Medicinal Chemistry (2006), 14(19), 6695-6712, database is CAplus and MEDLINE.

A new series of HIV protease inhibitors has been designed and synthesized based on the combination of the (R)-(hydroxyethylamino)sulfonamide isostere and the cyclic urea component of lopinavir. The series was optimized by replacing the 6-membered cyclic urea linker with an imidazolidine-2,4-dione which readily underwent N-alkylation to incorporate various methylene-linked heterocycle groups that bind favorably in site 3 of HIV protease. Significant improvements compared to lopinavir were seen in cell culture activity vs. wild-type virus (pNL4-3) and the lopinavir-resistant mutant virus A17 (generated by in vitro serial passage of HIV-1 (pNL4-3) in MT-4 cells). Select imidazolidine-2,4-dione containing PIs were also more effective at inhibiting highly resistant patient isolates Pt1 and Pt2 than lopinavir. Pharmacokinetic data collected for compounds in this series varied considerably when coadministered orally in the rat with an equal amount of ritonavir (5 mg/kg each). The AUC values ranged from 0.144 to 12.33 μg h/mL.

Bioorganic & Medicinal Chemistry published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Computed Properties of 4760-35-4.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Flosi, William J. published the artcileDiscovery of imidazolidine-2,4-dione-linked HIV protease inhibitors with activity against lopinavir-resistant mutant HIV, COA of Formula: C9H10N2O, the publication is Bioorganic & Medicinal Chemistry (2006), 14(19), 6695-6712, database is CAplus and MEDLINE.

A new series of HIV protease inhibitors has been designed and synthesized based on the combination of the (R)-(hydroxyethylamino)sulfonamide isostere and the cyclic urea component of lopinavir. The series was optimized by replacing the 6-membered cyclic urea linker with an imidazolidine-2,4-dione which readily underwent N-alkylation to incorporate various methylene-linked heterocycle groups that bind favorably in site 3 of HIV protease. Significant improvements compared to lopinavir were seen in cell culture activity vs. wild-type virus (pNL4-3) and the lopinavir-resistant mutant virus A17 (generated by in vitro serial passage of HIV-1 (pNL4-3) in MT-4 cells). Select imidazolidine-2,4-dione containing PIs were also more effective at inhibiting highly resistant patient isolates Pt1 and Pt2 than lopinavir. Pharmacokinetic data collected for compounds in this series varied considerably when coadministered orally in the rat with an equal amount of ritonavir (5 mg/kg each). The AUC values ranged from 0.144 to 12.33 μg h/mL.

Bioorganic & Medicinal Chemistry published new progress about 7467-35-8. 7467-35-8 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Alcohol, name is (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, and the molecular formula is C9H10N2O, COA of Formula: C9H10N2O.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Fozing Mekeuo, Ghislaine Ariane published the artcilePreparation of Functionalized Ayous Sawdust-carbon Nanotubes Composite for the Electrochemical Determination of Carbendazim Pesticide, HPLC of Formula: 79917-90-1, the publication is Electroanalysis (2022), 34(4), 667-676, database is CAplus.

Fine particles of Ayous sawdust (AS) were successfully modified by maleic anhydride to increase their accumulation capability towards carbendazim (Cbz). For a more efficient use of the biosourced material as electrode modifier for electrochem. detection, the functionalized particles were mixed with carbon nanotubes to yield a conductive composite. After electrochem. characterization, the modified GCE was applied to Cbz detection. A sensitivity of (2.61±0.08) μA M^-1 and a detection limit of 0.04μM were obtained under optimized exptl. conditions. Moreover, the designed sensor was found efficient for Cbz determination in real samples (spring water and com. pesticide product).

Electroanalysis published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, HPLC of Formula: 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

da Luz, Murilo published the artcilePoly(ionic liquid)s-based polyurethane blends: effect of polyols structure and ILs counter cations in CO₂ sorption performance of PILs physical blends, Computed Properties of 79917-90-1, the publication is Polymer Bulletin (Heidelberg, Germany) (2022), 79(8), 6123-6139, database is CAplus.

Carbon dioxide (CO₂) capture from natural gas, and further utilization is an essential issue for greenhouse gas reduction Poly(ionic liquid)s (PILs) assemble ILs unique properties, with those of polymers being versatile materials for CO₂ capture from flue gas (CO₂/N₂) and natural gas (CO₂/CH₄). PILs based on polyurethanes obtained with different polyols and ILs cations were blended in different proportions aiming to improve PILs CO₂ sorption capacity. Two different polyols structures (PC and PG) and ILs counter cations (imidazolium and phosphonium) were tested to evaluate how they influence PILs blends CO₂ sorption performance. PILs and PILs blends were characterized by SEC, FTIR, DSC, TGA, DMTA, AFM, and CO₂ sorption that were carried out using the pressure-decay technique. PILs blends presented good thermal stability and mech. properties. PILs blend polyurethane backbones compositions can be tuned aiming to increase CO₂ sorption capacity. As far as we know, all obtained PILs blends presented higher CO₂ sorption capacity results compared with other Poly(ionic liquid)s reported in the literature. The best CO₂ sorption result was obtained for PIL blend with imidazolium (PLIPC95-PG5-BMIM = 116.9 mgCO₂/g at 303.15 K and 10 bar).

Polymer Bulletin (Heidelberg, Germany) published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Computed Properties of 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Huang, Liurong published the artcileStructural and functional properties of collagen from tilapia scales pretreated by heat-assisted ionic liquids, Quality Control of 79917-90-1, the publication is Journal of Applied Polymer Science (2022), 139(14), 51903, database is CAplus.

This paper explores the structural and functional properties of collagen from tilapia scales pretreated by heat-assisted ionic liquids (ILs). Results show that the solubility of collagen was significantly influenced by the type and concentration of ILs. With the increase of IL concentration, a remarkable decrease in solubility of collagen was seen. Fluorescence spectra show that heat and IL pretreatments induced the exposure of chromophores. Changes in sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that subunits of collagen regenerated from most of the IL solvent systems were not destroyed. The functional properties of regenerated collagen were evaluated by gel strength, viscosity, water-binding capacity, and emulsifying capacity. Results show that all heat-assisted ILs pretreatments improved the gel strength and viscosity, and the highest gel strength and viscosity were both obtained in the collagen pretreated by heat-assisted [EMIM]Cl. Heat-assisted [BMIM]BF₄ pretreatment exhibited the lowest water-binding capacity. Heat-assisted [BDMIM]Cl pretreatment indicated superior effect on improving emulsifying capacity than other pretreatments due to its ability to break most of the hydrogen bonds in collagen mols., resulting in the formation of new re-aggregates with higher solubility and more hydrophobic groups.

Journal of Applied Polymer Science published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C8H15ClN2, Quality Control of 79917-90-1.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Lo, Pui Kin Tony published the artcileNickel(II)-Catalyzed Synthesis of Sulfinates from Aryl and Heteroaryl Boronic Acids and the Sulfur Dioxide Surrogate DABSO, Recommanded Product: Imidazo[1,2-a]pyridine-6-boronic acid, the publication is ACS Catalysis (2019), 9(12), 10668-10673, database is CAplus.

A redox-neutral Ni(II)-catalyzed sulfination of readily available aryl and heteroaryl boronic acids is reported. Using the combination of com. available, air-stable NiBr₂·(glyme), a com. available phenanthroline ligand and DABSO, boronic acids are efficiently converted to the corresponding sulfinate salts, which can be further elaborated to valuable sulfonyl-containing groups, including sulfones, sulfonamides, sulfonyl fluorides, and sulfonate esters. The catalyst loading can be reduced to 2.5 mol % on a gram scale. This practically simple protocol tolerates an unprecedented range of pharmaceutically relevant and electron-poor (hetero)aryl boronic acids, allowing the direct synthesis of active pharmaceutical ingredients.

ACS Catalysis published new progress about 913835-63-9. 913835-63-9 belongs to imidazoles-derivatives, auxiliary class Other Aromatic Heterocyclic,Boronic acid and ester,Boronic Acids,Boronic acid and ester, name is Imidazo[1,2-a]pyridine-6-boronic acid, and the molecular formula is C7H7BN2O2, Recommanded Product: Imidazo[1,2-a]pyridine-6-boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem