Tag: M.W=150-200

Vitale, Paola; D’Anna, Francesca; Ferrante, Francesco; Rizzo, Carla; Noto, Renato published the artcile< π-Conjugated diimidazolium salts: rigid structure to obtain organized materials>, Recommanded Product: 5-Bromo-1-methyl-1H-imidazole, the main research area is pi conjugated diimidazolium salt organized material.

Phenylene ethynylene based diimidazolium salts differing in the alkyl chain length borne on the imidazolium ion and anion nature were synthesized. Their properties were studied both in solution and in the solid state. Salts obtained were able to aggregate in organic solvent solution Aggregate formation was studied by performing concentration dependent measurements using UV-vis, fluorescence and Resonance Light Scattering. Furthermore, features of the aggregates were also investigated in the solid state by means of fluorescence and SEM measurements. Finally, D. Functional Theory calculations were performed to obtain insights into the interaction geometry in the salts investigated. Data collected evidence that aggregation processes are affected by a combined action of different factors derived from the nature of the salt and solvent. The above features also influence the morphol. of the aggregates as well as the ability of their thin films to give blue emission. On the whole, information gained could represent a useful starting point for applications of these salts in the optoelectronic field among others.

Physical Chemistry Chemical Physics published new progress about Aggregation. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Recommanded Product: 5-Bromo-1-methyl-1H-imidazole.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Salvitti, Chiara; Bortolami, Martina; Chiarotto, Isabella; Troiani, Anna; de Petris, Giulia published the artcile< The Knoevenagel condensation catalysed by ionic liquids: a mass spectrometric insight into the reaction mechanism>, HPLC of Formula: 700370-07-6, the main research area is anisaldehyde cyanoacetate methylimidazolium chloride Knoevenagel condensation mechanism.

The creation of carbon-carbon bonds is still a highly required topic in organic chem. for the capacity to give a wide variety of new products of industrial value. Accordingly, the Knoevenagel condensation between activated methylene compounds and aldehydes is one of the most known carbon coupling reactions. In this work, the catalytic activity of imidazolium-based ionic liquids (1-butyl-3-methylimidazolium acetate, 1-butyl-3-methylimidazolium chloride, 1-methyl-3-carboxymethylimidazolium chloride) was studied under solvent-free conditions and compared with that of sodium salts (sodium chloride, sodium acetate). Mass spectrometric techniques were used to monitor the formation of the reaction products and to detect the key intermediates of the process. Based on the catalyst employed different reaction mechanisms were highlighted, thus laying the foundation for the design of more specific and efficient catalysts.

New Journal of Chemistry published new progress about Electrospray ionization mass spectrometry. 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, HPLC of Formula: 700370-07-6.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

G-Dayanandan, Narendran; Scocchera, Eric W.; Keshipeddy, Santosh; Jones, Heather F.; Anderson, Amy C.; Wright, Dennis L. published the artcile< Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks>, Electric Literature of 1003-21-0, the main research area is aryl propyne preparation reduction substitution arylalkynyl carbinol.

To develop next generation antifolates for the treatment of trimethoprim-resistant bacteria, synthetic methods were needed to prepare a diverse array of 3-aryl-propynes with various substitutions at the propargyl position. A direct route was sought whereby nucleophilic addition of acetylene to aryl carboxaldehydes would be followed by reduction or substitution of the resulting propargyl alc. The direct reduction, methylation, and dimethylation of these readily available alcs. provide efficient access to this uncommon functional array. In addition, an unusual silane exchange reaction was observed in the reduction of the propargylic alcs.

Organic Letters published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Electric Literature of 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Mergehenn, R.; Haase, W.; Allmann, R. published the artcile< Crystal structures of chloro- and γ-bromo-(2-dibutylaminoethanolato)copper(II)>, Related Products of 1003-21-0, the main research area is mol structure copper aminoethanolato halo; chloro copper aminoethanolato structure; bromo copper aminoethanolato structure.

Addnl. data considered in abstracting and indexing are available from a source cited in the original document. The crystal structures of halo-(2-dibutylaminoethanolato)copper(II) [(C10H22NOCuX)4, X = Cl (I), Br (II) were determined by single-crystal x-ray diffractometer methods using 4331 and 3915 independent reflections, resp., from 3-dimensional diffractometer data (Mo Ka radiation). The isomorphous compounds belong to space group P1̅ with a 15·563(10), b 16·280(11), c 11·659(8) Å, α 93·49(10), β 100·32(10), γ 112·51(10)° for I and a 15·539(10), b 16·452(11), c 11·766(8) Å, α 94·58(10), β 100·65(10), γ 111·67(10)° for II. The structures were refined by least-squares methods to final residuals of 0.084 and 0.071, resp. The tetrameric clusters of cubane-type mol. structures have mean Cu-Cu separations of 3·240(3) and 3·268(3) Å. The Cu coordination is distorted square pyramidal with Cu bonded to 3 O, 1N, and 1 halogen. The distance to the apical O is longer than to the other 2 O. The average bond lengths are Cu-O 1·9778) and 1·963(10) Å (short Cu-O separations), Cu-O 2·424(8) and 2·480(10) Å (long-Cu-O separations), Cu-N 2·054(11) and 2·066(13) Å, and Cu-hal 2·234(4) and 2·382(3) Å.

Acta Crystallographica, Section B: Structural Crystallography and Crystal Chemistry published new progress about Crystal structure. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Related Products of 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Wang, Mo; Zhang, Zhenfeng; Xie, Fang; Zhang, Wanbin published the artcile< Cu-catalyzed amidation of halogenated imidazoles>, Reference of 1003-21-0, the main research area is imidazole halo amide cyclic copper amidation catalyst; amido imidazole preparation; amide cyclic heterocycle halo copper amidation catalyst; heterocycle amido preparation.

An efficient methodol. involving the Cu-catalyzed amidation of halogenated imidazoles has been successfully developed. The amidated product of 5-bromo-1-alkylimidazole was further applied to the synthesis of a new chiral imidazole nucleophilic catalyst for the kinetic resolution of secondary alcs.

Chemical Communications (Cambridge, United Kingdom) published new progress about Amidation. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Reference of 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Iida, Hiroki; Umebayashi, Naofumi; Yashima, Eiji published the artcile< Photoswitchable organocatalysis in acylation of alcohol using dithienylethene-linked azoles>, SDS of cas: 1003-21-0, the main research area is dithienylethene linked azole preparation photoswitchable organocatalyst acylation alc.

Three novel dithienylethenes bearing azole derivatives were synthesized and found to undergo reversible photocyclization of the dithienylethene units upon alternate irradiation with UV and visible light. Among them, the dithienylethene-linked imidazole and N-phenylimidazole exhibited a relatively high organocatalytic activity for the acylation of 2-decanol with acetic anhydride, and the catalytic activity of the dithienylethene-linked imidazole could be switched by reversible photoinduced cyclization/cycloreversion of the dithienylethene unit.

Tetrahedron published new progress about Acylation. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, SDS of cas: 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Garbaccio, Robert M.; Brnardic, Edward J.; Fraley, Mark E.; Hartman, George D.; Hutson, Pete H.; O’Brien, Julie A.; Magliaro, Brian C.; Uslaner, Jason M.; Huszar, Sarah L.; Fillgrove, Kerry L.; Small, James H.; Tang, Cuyue; Kuo, Yuhsin; Jacobson, Marlene A. published the artcile< Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor>, Product Details of C8H4ClN3, the main research area is oxazolo benzimidazole derivative preparation allosteric modulator mGluR2 receptor antipsychotic; GPCR; Oxazolobenzimidazoles; allosteric modulators; hyperlocomotion model; metabotropic glutamate 2 receptor; schizophrenia.

Novel oxazolobenzimidazoles are described as potent and selective pos. allosteric modulators of the metabotropic glutamate receptor 2. The discovery of this class and optimization of its phys. and pharmacokinetic properties led to the identification of potent and orally bioavailable compounds (20 and 21) as advanced leads. Compound 20 (TBPCOB) was shown to have robust activity in a PCP-induced hyperlocomotion model in rat, an assay responsive to clin. antipsychotic treatments for schizophrenia.

ACS Medicinal Chemistry Letters published new progress about Antipsychotics. 401567-00-8 belongs to class imidazoles-derivatives, and the molecular formula is C8H4ClN3, Product Details of C8H4ClN3.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Kochergin, P. M. published the artcile< Imidazole series. XV. Reaction products of N,N'-dimethyloxamide with pentahalo phosphorus compounds>, Recommanded Product: 5-Bromo-1-methyl-1H-imidazole, the main research area is .

14660a. Heating 2 kg. PCl5 with 550 g. (CONHMe)2 1-1.5 hrs. at 95-8° (exothermic initially), followed by further 1.6 hrs. after cessation of exothermic reaction, gave 50.6% 1-methyl-5-chloroimidazole, b9 84°, b10 87°, n22D 1.5120 (picrate m. 167-8°), unreacted amide, and 1-methyl-4,5-dichloroimidazole, m. 58.5-59° (picrate m. 130.5-1.5°; HCl salt m. 161-3°; nitrate m. 122°; sulfate m. 83-5°). Similar reaction of 11.6 g. (CONHMe)2 with 91.6 g. PCl5 and 250 ml. POCl3 in 0.5 hr. at 40-50°, then 1.5 hrs. at 100°, gave a low yield of 1-methyl-2,4,5-trichloroimidazole, m. 75.5-6° (petr. ether), 1-methyl-4,5-dichloroimidazole, isolated as the picrate, and 1-methyl-5-chloroimidazole. Heating 104 g. PBr5 with 14 g. (CONHMe)2 2.1 hrs. on a steam bath gave 19.6% 1-methyl-4,5-dibromoimidazole, m. 79-80° (picrate m. 149.5-50.5°), and 1-methyl-5-bromoimidazole, isolated as the picrate, m. 190-1°. Nitration of the mixed crude mono- and dibromo derivatives with mixed acid 2 hrs. at 100° gave 1-methyl-4-nitro-5-bromoimidazole, m. 180-1°. Heating (CONHMe)2 with PBr5 in POCl3 in 1 hr. at 60-70° and 2 hrs. at reflux gave 1-methyl-2,4,5-tribromoimidazole, m. 93-4°, 1-methyl-4,5-dibromoimidazole, and 1-methyl-5-bromoimidazole, isolated as the picrate.

Zhurnal Obshchei Khimii published new progress about Group 15 element halides, phosphorus halides. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Recommanded Product: 5-Bromo-1-methyl-1H-imidazole.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Vitale, Paola; D’Anna, Francesca; Ferrante, Francesco; Rizzo, Carla; Noto, Renato published the artcile< π-Conjugated diimidazolium salts: rigid structure to obtain organized materials>, Recommanded Product: 5-Bromo-1-methyl-1H-imidazole, the main research area is pi conjugated diimidazolium salt organized material.

Phenylene ethynylene based diimidazolium salts differing in the alkyl chain length borne on the imidazolium ion and anion nature were synthesized. Their properties were studied both in solution and in the solid state. Salts obtained were able to aggregate in organic solvent solution Aggregate formation was studied by performing concentration dependent measurements using UV-vis, fluorescence and Resonance Light Scattering. Furthermore, features of the aggregates were also investigated in the solid state by means of fluorescence and SEM measurements. Finally, D. Functional Theory calculations were performed to obtain insights into the interaction geometry in the salts investigated. Data collected evidence that aggregation processes are affected by a combined action of different factors derived from the nature of the salt and solvent. The above features also influence the morphol. of the aggregates as well as the ability of their thin films to give blue emission. On the whole, information gained could represent a useful starting point for applications of these salts in the optoelectronic field among others.

Physical Chemistry Chemical Physics published new progress about Aggregation. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Recommanded Product: 5-Bromo-1-methyl-1H-imidazole.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Salvitti, Chiara; Bortolami, Martina; Chiarotto, Isabella; Troiani, Anna; de Petris, Giulia published the artcile< The Knoevenagel condensation catalysed by ionic liquids: a mass spectrometric insight into the reaction mechanism>, HPLC of Formula: 700370-07-6, the main research area is anisaldehyde cyanoacetate methylimidazolium chloride Knoevenagel condensation mechanism.

The creation of carbon-carbon bonds is still a highly required topic in organic chem. for the capacity to give a wide variety of new products of industrial value. Accordingly, the Knoevenagel condensation between activated methylene compounds and aldehydes is one of the most known carbon coupling reactions. In this work, the catalytic activity of imidazolium-based ionic liquids (1-butyl-3-methylimidazolium acetate, 1-butyl-3-methylimidazolium chloride, 1-methyl-3-carboxymethylimidazolium chloride) was studied under solvent-free conditions and compared with that of sodium salts (sodium chloride, sodium acetate). Mass spectrometric techniques were used to monitor the formation of the reaction products and to detect the key intermediates of the process. Based on the catalyst employed different reaction mechanisms were highlighted, thus laying the foundation for the design of more specific and efficient catalysts.

New Journal of Chemistry published new progress about Electrospray ionization mass spectrometry. 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, HPLC of Formula: 700370-07-6.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem