Tag: M.W=150-200

Song, Honghong; Zhang, Jing; Song, Pengfei; Xiong, Yubing published the artcile< Maize-like ionic liquid@polyaniline nanocomposites for high performance supercapacitor>, Synthetic Route of 700370-07-6, the main research area is polyaniline nanocomposite ionic liquid supercapacitor tunable morphol.

In this study, ionic liquids (IL) containing carboxyl and different alkyl chains were fabricated and used to dope polyaniline (PANI). The results revealed that IL-PANI composites could be facilely obtained via template-free polymerization of aniline using ammonium persulfate as the oxidant. The as-prepared IL-PANI composites were measured by FT-IR, XPS, and SEM. Electrochem. performances of IL-PANI nanocomposites were investigated by cyclic voltammetry and galvanostatic charge/discharge. The results indicate that the alkyl chains of ILs have an important influence on the morphol. and capacitance performance of IL-PANI electrode materials. With the shorter alkyl group in ILs, IL-PANI materials presented higher specific capacitance. Especially, 1-vinyl-3-carboxymethyl-imidazolium chloride ([VCMIm]Cl)-PANI composite presented the highest specific capacitance. Cycling performance measurement demonstrated that 82% capacitance retention could be achieved after 1000 cycles in 0.5 M H2SO4 aqueous solution Therefore, our strategy provides a new technique for PANI nanocomposites with tunable morphol. and high performance.

e-Polymers published new progress about Binding energy. 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, Synthetic Route of 700370-07-6.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Thripuram, Vijaya Durga; Bollikolla, Hari Babu; Reddy Mule, Siva Nagi; Battula, Sailaja Kumari; Ala, Vasu Babu published the artcile< A Novel Approach for Substitution of Sulfonate Group by (1H)-imidazole moiety: An Application for Synthesis of Novel Benzyl Imidazolylcarbamates>, SDS of cas: 1003-21-0, the main research area is benzyl imidazolylcarbamate preparation.

An efficient and convenient substitution protocol was developed for the synthesis of novel benzyl (1-methyl-1H-imidazol-5-yl) (aryl) Me carbamate derivatives from alpha-amido sulfones with a solution 5-bromo-1-methyl-(1H)-imidazole in THF under Hexamethylphosphoramide (HMPA) and t-BuLi medium at -78° to room temperature The reactions were monitored with TLC for about 3-4 h.The yields obtained were also considerably good.

Letters in Organic Chemistry published new progress about Aromatic carbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, SDS of cas: 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Collins, Mark A.; Hudak, Valerie; Bender, Reinhold; Fensome, Andrew; Zhang, Puwen; Miller, Lori; Winneker, Richard C.; Zhang, Zhiming; Zhu, Yuan; Cohen, Jeffrey; Unwalla, Rayomond J.; Wrobel, Jay published the artcile< Novel pyrrole-containing progesterone receptor modulators>, Synthetic Route of 1003-21-0, the main research area is indolone pyrrolyl preparation progesterone receptor agonist antagonist; benzoxazinone pyrrolyl preparation progesterone receptor agonist antagonist.

A series of 1,4-dihydro-2H-[d][3,1]-benzoxazin-2-one and 1,3-dihydro-[3H]-indol-2-one containing 6- or 5-, resp., appended substituted pyrrole moieties were synthesized and evaluated for their ability to modulate the activity of the progesterone receptor (PR). Key structural changes to the pyrrole moieties of these mols. were shown to have a predictive influence as to whether the compounds behaved as PR agonists or antagonists. Compounds with the 5′-cyano-2′-pyrrole moiety were shown to be potent PR agonists (EC50’s of 1.1, 1.8, and 2.8 nM, resp.). Compounds with the 5′-nitro-2′-pyrrole moiety were shown to be PR antagonists (IC50’s of 180 and 36 nM, resp.).

Bioorganic & Medicinal Chemistry Letters published new progress about Progesterone receptors Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Synthetic Route of 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Sarkar, Satavisha; Banerjee, Arghya; Yao, Wang; Patterson, Eric V.; Ngai, Ming-Yu published the artcile< Photocatalytic Radical Aroylation of Unactivated Alkenes: Pathway to β-Functionalized 1,4-, 1,6-, and 1,7-Diketones>, Related Products of 1003-21-0, the main research area is unsym diketone preparation photoredox catalysis; aroyl chloride unactivated alkene aroylation photochem; 1,n-diketones; aroylation; migration; photoredox catalysis; unactivated alkenes.

The development of a photocatalytic strategy for the synthesis of β-functionalized unsym. 1,4-, 1,6-, and 1,7-diketones from aroyl chlorides and unactivated alkenes at room temperature is reported. The mild reaction conditions not only tolerate a wide range of functional groups and structural moieties, but also enable migration of a variety of distal groups including (hetero)arenes, nitrile, aldehyde, oxime derivative, and alkene. The efficiency of chirality transfer, factors that control the distal-group migration, and synthesis of carbocycles and heterocycles from the diketones are also described. Mechanistic studies suggest a reaction pathway involving a photocatalytic radical aroylation of unactivated alkenes followed by a distal-group migration, oxidation, and deprotonation to afford the desired diketones.

ACS Catalysis published new progress about Alcohols, unsaturated Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (tertiary). 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Related Products of 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Yongtao; Lin, Wenwei; Wright, William C.; Chai, Sergio C.; Wu, Jing; Chen, Taosheng published the artcile< Building a Chemical Toolbox for Human Pregnane X Receptor Research: Discovery of Agonists, Inverse Agonists, and Antagonists Among Analogs Based on the Unique Chemical Scaffold of SPA70>, Synthetic Route of 1003-21-0, the main research area is pregnane X receptor agonist antagonist inverse agonist SPA70 analog.

Pregnane X receptor (PXR) plays roles in detoxification and other physiol. processes. PXR activation may enhance drug metabolism (leading to adverse drug reactions) or inhibit inflammation. Therefore, PXR agonists, antagonists, and inverse agonists may serve as research tools and drug candidates. However, a specific PXR modulator with an associated structure-activity relationship is lacking. Based on the scaffold of specific human PXR (hPXR) antagonist SPA70 (10), we developed 81 SPA70 analogs and evaluated their receptor-binding and cellular activities. Interestingly, analogs with subtle structural differences displayed divergent cellular activities, including agonistic, dual inverse agonistic and antagonistic, antagonistic, and partial agonistic/partial antagonistic activities (as in compounds 111, 10, 97, and 42, resp.). We generated a pharmacophore model that represents 81 SPA70 analogs, and docking models that correlate strong interactions between the compounds and residues in the AF-2 helix with agonistic activity. These compounds are novel chem. tools for studying hPXR.

Journal of Medicinal Chemistry published new progress about Cytotoxicity. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Synthetic Route of 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Padmaja, R. D.; Chanda, Kaushik published the artcile< A robust and recyclable ionic liquid-supported copper(II) catalyst for the synthesis of 5-substituted-1H-tetrazoles using microwave irradiation>, Synthetic Route of 700370-07-6, the main research area is substituted tetrazole preparation green chem microwave irradiation; nitrile sodium azide dipolar cycloaddition; ionic liquid supported copper catalyst preparation.

A novel and robust ionic liquid-supported copper(II) catalyst has been developed and explored for the efficient synthesis of 5-substituted-1H-tetrazoles I (R = H, 3-O2N, 4-Br, etc.) using microwave irradiation The ionic liquid-supported catalyst facilitated the efficient isolation of tetrazole products with high purity by simple extraction with organic solvent. Recovered ionic liquid-supported copper(II) catalyst could be recycled for three times for the synthesis of tetrazole products with high purity. This synthetic protocol offers a very clean, convenient, and microwave-assisted environment-friendly method for the efficient synthesis of 5-substituted-1H-tetrazoles with high yield.

Research on Chemical Intermediates published new progress about [3+2] Cycloaddition reaction. 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, Synthetic Route of 700370-07-6.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Kong, Juanhua; Li, Lixia; Zeng, Qiang; Long, Jinxing; He, Hongyan; Wang, Yingying; Liu, Sijie; Li, Xuehui published the artcile< Production of 4-Ethylphenol from Lignin Depolymerization in a Novel Surfactant-Free Microemulsion Reactor>, HPLC of Formula: 700370-07-6, the main research area is ethylphenol lignin depolymerization surfactant microemulsion reactor.

In order to meet the requirements of sustainable development, the production of aromatic compounds from renewable biomass is of great concern. Herein, a surfactant-free microemulsion (SFME) system composed of n-octane, 2-propanol, and water was explored for the depolymerization of lignin though a hydrogen transfer reaction of 2-propanol with acidic ionic liquids (ILs) as catalysts. Exptl. results show that the phenol monomer yield from bagasse lignin in the SFME system is at least 4 times higher than that in its corresponding water-free binary system, together with a high selectivity for 4-ethylphenol of 67.8%. In particular, the results also reveal that the controllable polarity and large surface area of the SFME and the aggregation of lignin at the SFME surface are key factors in response to the enhanced yields of phenolic monomers through intensive characterizations. Mechanism studies imply that this system tailors mainly the esterified p-coumarate unit in lignin, and 4-ethylphenol is produced by a cascade reaction, involving hydrolysis, decarboxylation, and hydrogenation. Furthermore, this SFME system also exhibits excellent performance for the depolymerization of other herbaceous lignins, yielding 128.1 mg g-1 phenolic monomers with 59.1% 4-ethylphenol selectivity for corncob lignin. It is thus believed that the process intensification by microemulsion can significantly demonstrate unprecedented potential to accomplish highly efficient lignin conversion.

Industrial & Engineering Chemistry Research published new progress about Acidity function, Hammett. 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, HPLC of Formula: 700370-07-6.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Lu, Yixia; Hu, Jian; Zeng, Yanbo; Zhu, Ying; Wang, Hailong; Lei, Xiaoling; Huang, Shisi; Guo, Longhua; Li, Lei published the artcile< Electrochemical determination of rutin based on molecularly imprinted poly (ionic liquid) with ionic liquid-graphene as a sensitive element>, Category: imidazoles-derivatives, the main research area is rutin graphene molecularly imprinted polyionic liquid electrochem sensor.

A novel electrochem. sensor for rutin determination based on molecularly imprinted poly (ionic liquid) (MIPIL)/ionic liquid-graphene (IL-GR) modified electrode was developed. MIPIL was synthesized via free radical polymerization using rutin as the template, 1-allyl-3-Et imidazolium bromide ([AEIm]Br) as the functional monomer and 1,4-butanediyl-3,3′-bis-L-vinylimidazolium dibromide ([V2C4(mim)2]Br2) as the crosslinker. The composite of IL-GR as an electrode sensitive element was prepared using carboxymethyl-3-methylimidazolium chloride ([HO2CMMIm]Cl) by one-step ultrasound method. Fourier transform IR spectroscopy and scanning electron microscope were used to characterize IL-GR and MIPIL. The increased surface area and conductivity of IL-GR/GCE improved the sensitivity of rutin sensor. Under the optimum condition, good linearity for rutin anal. by the MIPIL-based sensor was obtained from 0.03 to 1μM. A low limit of detection for rutin was 0.01μM (S/N = 3). The MIPIL-based sensor demonstrated superiority on DPV response compared to the imprinted sensors based on traditional crosslinkers. The proposed sensor presented good selectivity for rutin and successfully applied for rutin determination in tablets with RSD of 3.05% and the average recovery range was 98.3%.

Sensors and Actuators, B: Chemical published new progress about Atom transfer radical polymerization. 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, Category: imidazoles-derivatives.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Gong, Liao-Kuo; Du, Ke-Zhao; Huang, Xiao-Ying published the artcile< PbX2(OOCMMIm) (X = Cl, Br): photoluminescent organic-inorganic hybrid lead halide compounds with high proton conductivity>, Name: 1-carboxymethyl-3-methylimidazolium chloride, the main research area is lead carboxymethylmethylimidazolium halide preparation photoluminescence proton conductivity; crystal structure lead carboxymethylmethylimidazolium chloride bromide inorganic organic hybrid.

Differences in the electronegativity and hydrophilicity of halogens lead to differences in proton-conducting and photoluminescence properties in hybrid organic-inorganic lead halide compounds of [PbX2(OOCMMIm)]n (X = Cl 1, Br 2, HOOCMMIm = 1-carboxymethyl-3-methylimidazolium).

Dalton Transactions published new progress about Activation energy (proton-transport). 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, Name: 1-carboxymethyl-3-methylimidazolium chloride.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Pohida, Katherine; Maloney, David J.; Mott, Bryan T.; Rai, Ganesha published the artcile< Room-Temperature, Copper-Free Sonogashira Reactions Facilitated by Air-Stable, Monoligated Precatalyst [DTBNpP] Pd(crotyl)Cl>, Related Products of 1003-21-0, the main research area is Sonogashira coupling palladium DTBNpP crotyl catalyzed.

A novel application of [DTBNpP] Pd(crotyl)Cl (DTBNpP = di-tert-butylneopentylphosphine) (P2), an air-stable, com.-available palladium precatalyst that allows rapid access to a mono-ligated state, has been identified for room temperature, copper-free Sonogashira couplings of challenging aryl bromides and alkynes. The mild reaction conditions with TMP in DMSO afford up to 97% yields, excellent functional group tolerability, and broad reaction compatibility with access to one-pot indole formation.

ACS Omega published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent). 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Related Products of 1003-21-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem