Tag: M.W=200-300

In an article, author is Anoaica, Paul Gabriel, once mentioned the application of 641571-11-1, Computed Properties of C11H10F3N3, Name is 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, molecular formula is C11H10F3N3, molecular weight is 241.2124, MDL number is MFCD11846236, category is imidazoles-derivatives. Now introduce a scientific discovery about this category.

QSAR study for classes with a broad range of biological activity using electronegativity descriptors for OMO-UMO quantum states. Clotrimazole imidazole derivatives with antiftingal activity

The class of clotrimazole imidazole derivatives having a broad spectrum of antimycotic activity has been studied using fingerprint descriptors based on electronegativity, of the occupied molecular orbitals (OMO) and unoccupied molecular orbitals (UMO). The Hansch equation Kd = a(0) + a(I)X(I), where X, = OMO / UMO electronegativity allows us to identify the nature of the atoms involved in ligand (drug)-receptor interactions, as well as the nature of those interactions.

If you are interested in 641571-11-1, you can contact me at any time and look forward to more communication. Computed Properties of C11H10F3N3.

Chemistry, like all the natural sciences, Product Details of 38668-46-1, begins with the direct observation of nature¡ª in this case, of matter.38668-46-1, Name is 6-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-1,3,5-triazine-2,4-diamine, SMILES is CC1=NC=CN1CCC2=NC(N)=NC(N)=N2, belongs to imidazoles-derivatives compound. In a document, author is Gwiazda, Maciej, introduce the new discover.

Highly substituted imidazole derivatives from a new four-component synthesis employing methoxyallene

A novel four-component reaction of alkoxyallenes with imines, iodine, and nitriles provided highly substituted imidazole derivatives in high overall yields. The simple three step protocol, exemplified by the reaction of methoxyallene (1) with imine 2, acetonitrile, and iodine leading to iodoethenyl imidazole 6 is presented with full experimental detail. Imidazole 6 could be further functionalized by palladium-catalyzed couplings yet offering an entry into diversity-oriented synthesis.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 38668-46-1. Product Details of 38668-46-1.

Electric Literature of 38668-46-1, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 38668-46-1, Name is 6-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-1,3,5-triazine-2,4-diamine, SMILES is CC1=NC=CN1CCC2=NC(N)=NC(N)=N2, belongs to imidazoles-derivatives compound. In a article, author is Zheng, Hui, introduce new discover of the category.

One-pot Synthesis of 2,4,5-trisubstituted Imidazoles Catalyzed by Lipase

A simple and efficient protocol of synthesizing 2,4,5-trisubstituted imidazoles has been developed using lipase as a novel catalyst under mild conditions. A series of imidazole derivatives were synthesized with good yields. The probable enzymatic mechanism was proposed. This method expands the catalytic scope of lipase and provides a novel method to prepare imidazole derivatives.

Electric Literature of 38668-46-1, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 38668-46-1.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, molecular formula is C14H19N3O2. In an article, author is Jiang, Weidong,once mentioned of 3543-73-5, Quality Control of Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate.

Hydrolytic cleavage of p-nitrophenyl picolinate by mononuclear Zn(II) and Co(II) complexes with imidazole derivative in CTAB micellar solution

One new hydroxyl-functionalized imidazole derivative (L) was synthesized and characterized. Further, the related mononuclear zinc(II) and cobalt(II) complexes were prepared and used as mimic hydrolases to catalyze the hydrolytic cleavage of p-nitrophenyl picolinate (PNPP) in buffered aqueous solution and a micellar solution of cetyltrimethylammonium bromide (CTAB). Observations show that for all of catalytic systems, the hydrolysis of PNPP was pH-dependent in the pH range of 7.00-8.20. Besides, hydrolysis rates of PNPP displayed a constant increase with the increasing concentration of substrate. In the case of CoL-containing system, moreover, much greater acceleration for PNPP hydrolysis was observed in comparison with the ZnL-containing system. However, micellar effect of CTAB micelle aggregates on the PNPP hydrolysis was not obvious only showing 1.0 similar to aEuro parts per thousand 1.3 folds rate difference in contrast to buffered aqueous solution.

Interested yet? Keep reading other articles of 3543-73-5, you can contact me at any time and look forward to more communication. Quality Control of Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate.

Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 16079-88-2, Name is 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione, SMILES is O=C1N(Cl)C(C(C)(C)N1Br)=O, in an article , author is Zhou, Linlei, once mentioned of 16079-88-2, COA of Formula: C5H6BrClN2O2.

Effect of imidazole derivatives in triphenylamine-based organic dyes for dye-sensitized solar cells

In order to study the influence of imidazole derivatives in triphenylamine-based organic dyes, two different imidazole derivatives are introduced into the phenyl ring of the triphenylamine core, coded as TPA-B5 and TPA-B6, respectively. The photophysical and electrochemical properties of the dyes are investigated by UV-vis spectroscopy and cyclic voltammetry. TPA-B5 increases the molar extinction coefficients and lambda(max) because of the extension of the pi-conjugation structure of the dye and non-planar structure of imidazole derivative. However, TPA-B6 does not increase the molar extinction coefficients and lambda(max) compared with a simple triphenylamine derived dye (TPA-1), which may be due to the planar structure of imidazole derivative and benzene ring. The structure of TPA-B6 is in favor of the formation of dye aggregates on the semiconductor surface and the recombination of conduction band electrons with triiodide in the electrolyte. Overall conversion efficiencies of 3.13% and 1.21% under full sunlight (AM 1.5G, 100 mW cm(-2)) irradiation are obtained for DSSCs based on the two new dyes, under the same conditions, the dye TPA-1 and ditetrabutylammonium cis-bis(isothiocyanato) bis(2,2′-bipyridyl-4,4′-dicarboxylato) ruthenium(II) (N719) give overall conversion efficiencies of 2.23% and 5.38%, respectively. Although the overall conversion efficiencies of these dyes are not very high, the results will still afford significant value for future development of efficient D-pi-A sensitizers. (C) 2013 Elsevier B.V. All rights reserved.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 16079-88-2, you can contact me at any time and look forward to more communication. COA of Formula: C5H6BrClN2O2.

Chemistry, like all the natural sciences, Recommanded Product: 144689-94-1, begins with the direct observation of nature¡ª in this case, of matter.144689-94-1, Name is Diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate, SMILES is O=C(C1=C(C(OCC)=O)NC(CCC)=N1)OCC, belongs to imidazoles-derivatives compound. In a document, author is Panigrahi, Ahwan, introduce the new discover.

Iodine-Catalyzed C-H Functionalization of Cyclopentenedione with Benzamidine: A Double Dehydrogenative Oxidative Cyclization to Access Fused Imidazoles

A double C-H functionalization of cyclopentenedione with benzamidine hydrochloride catalyzed by iodine has been disclosed for synthesizing fused imidazole derivatives. This methodology leads to a variety of fused imidazole derivatives and requires a sub-stoichiometric amount of iodine as a catalyst and aqueous tert-butyl hydroperoxide (TBHP) as an oxidant. This reaction involves a double-cross dehydrogenative coupling (CDC) of 1,3-cyclopentenedione and benzamidine hydrochloride to form two C-N bonds in a consecutive manner within short reaction time. A plausible mechanism has been proposed based on the mass spectrometric analysis.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 144689-94-1. Recommanded Product: 144689-94-1.

Synthetic Route of 16079-88-2, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 16079-88-2, Name is 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione, SMILES is O=C1N(Cl)C(C(C)(C)N1Br)=O, belongs to imidazoles-derivatives compound. In a article, author is Mao, Pu, introduce new discover of the category.

Synthesis of Novel Chiral Thioether Ligands Containing Imidazole Rings Based on Natural Amino Acids

Using commercially available natural amino acids (L-Val, L-Leu, L-Phe) as chiral precursors, a series of N-substituted imidazole derivatives containing chiral groups was synthesized from the condensation reaction of amino acids, formaldehyde, glyoxal, and ammonia. Through esterification, reduction, chlorination, and subsequent substitution by thiols, chiral thioethers containing imidazole rings were synthesized, and the synthetic conditions were optimized. All the intermediates and the final products were characterized by NMR, ESI MS, HR MS, and IR.

Synthetic Route of 16079-88-2, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 16079-88-2.

Synthetic Route of 144689-94-1, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 144689-94-1, Name is Diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate, SMILES is O=C(C1=C(C(OCC)=O)NC(CCC)=N1)OCC, belongs to imidazoles-derivatives compound. In a article, author is Singh, Ambrish, introduce new discover of the category.

Electrochemical, surface and quantum chemical studies of novel imidazole derivatives as corrosion inhibitors for J55 steel in sweet corrosive environment

The corrosion inhibition performance of three novel imidazole derivatives namely 2-(4-methoxyphenyl)4,5-diphenyl-imidazole (M-1), 4,5-diphenyl-2-(p-tolyl)-imidazole (M-2) and 2-(4-nitrophenyl)-4,5-diphenyl-imidazole (M-3) for J55 steel in CO2 saturated brine solution was studied by weight loss method, electrochemical impedance spectroscopy (EIS), potentiodynamic polarization, scanning electrochemical microscopy (SECM), contact angle, scanning electron microscope (SEM), atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS) and quantum chemical calculation. M-1 exhibited the best inhibition efficiency of 93% at 400 mg/L concentration. The adsorption of the imidazole derivatives obeyed the Langmuir adsorption isotherm. Contact angle measurement reveals the hydrophobic nature of J55 steel in presence of inhibitors. Quantum chemical calculation well supports the experimental results. (C) 2017 Elsevier B.V. All rights reserved.

Synthetic Route of 144689-94-1, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 144689-94-1.

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 16079-88-2, Name is 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione, molecular formula is C5H6BrClN2O2, belongs to imidazoles-derivatives compound. In a document, author is Birsan, Magdalena, introduce the new discover, Recommanded Product: 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione.

Antifugal Action of Imidazole Derivatives from New Pharmaceutical Forms on Various Strains of Candida

The antifungal activity of imidazole derivatives was tested on three types of Candida, respectively C. albicans, C. sake, and C. glabrata. The antifungal activity was compared with the activity of miconazole nitrate in 16 new formulations of oral biomucoadhesive tablets, with the purpose of being used in oral candidiasis. All the 16 formulations of biomucoadhesive tablets which contain 25 mg miconazole have a good antifungal action; the diameter of the inhibition area is over 20 mm in all the three strains of Candida. The second goal was to compare the activity of miconazole nitrate with other antifungal substances: clotrimazole (benzyl imidazole derivative), nistatin (polyenic macrolide), econazole (phenyl – ethyl – imidazole derivative), and fluconazole (triazole derivative). Good results, obtained by measuring the diameter of the inhibition area, were shown by econazole, with a diameter of over 22 mm, but this imidazole derivative does not penetrate the stratum corneum well enough, which implies a much longer treatment than miconazole. The third goal was the assessment of the antifungal activity of the 16 formulations of biomucoadhesive tablets by means of establishing the minimum inhibitory concentration (MIC) and of minimum fungicide concentration (MFC).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 16079-88-2. Recommanded Product: 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione.

Synthetic Route of 641571-11-1, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 641571-11-1, Name is 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, SMILES is CC1=C[N](C=N1)C2=CC(=CC(=C2)N)C(F)(F)F, belongs to imidazoles-derivatives compound. In a article, author is Smitha, M., introduce new discover of the category.

Two novel imidazole derivatives – Combined experimental and computational study

Two novel imidazole derivatives, 2-chloro-4,5-dimethyl-1-phenyl-1H-imidazole (C11H11ClN2)(PHENYLI) and 2-chloro-4,5-dimethyl-1-(o-tolyl)-1H-imidazole (C12H13ClN2) (TOLYLI), have been obtained by a procedure based on solvent-free synthesis pathway. Newly synthetized imidazole derivatives have been characterized experimentally by IR, FT-Raman and NMR techniques, while their reactive properties have been predicted on the basis of density functional theory (DFT) calculations and molecular dynamics (MD) simulations. The NLO behavior of the title compounds is greater than that of the standard NLO material urea. MEP analysis gives the most reactive sites in the molecules. TOLYLI compound reveals anti-bacterial activity against all four bacterial strain in both gram positive and gram negative bacteria and PHENYL! compound showed in gram positive and gram negative bacteria both with very good immense and has more sensitive. Interactions of these novel imidazole derivatives with selected protein have been computationally investigated by molecular docking procedure. The docking studies suggest that the compounds might exhibit inhibitory activity against APO-liver alcohol dehydrogenase inhibitor. (C) 2018 Elsevier B.V. All rights reserved.

Synthetic Route of 641571-11-1, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 641571-11-1 is helpful to your research.