Tag: M.W=50-100

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Application In Synthesis of 1739-84-0.

Ramezanzadeh, Forough;Mamaghani, Manouchehr;Fallah-Bagher Shaidaei, Hossein;Sheykhan, Mehdi research published 《 Synthesis and Application of Imidazolium-Based Ionic Liquid Supported on Hydroxyapatite Encapsulated γ-Fe₂O₃ Nanocatalyst in Preparation of Pyrido[2,3-d]Pyrimidines》, the research content is summarized as follows. Synthesis of novel 2-amino-5-aryl-7-(1-methyl-1H-pyrrol-2-yl)-4-oxo-3,4,5,8-tetrahydro-pyrido[2,3-d]pyrimidine-6-carbonitrile derivatives I (Ar = 4-chlorophenyl, thiophen-2-yl, naphthalen-1-yl) is reported by the reaction of 2,6-diaminopyrimidin-4(3H)-one, 3-(1-methy-1H-pyrrol-2-yl)-3-oxopropane nitrile and aryl aldehydes ArCHO in the presence of newly synthesized imidazolium based ionic liquid supported on hydroxyapatite encapsulated γ-Fe₂O₃ nanocatalyst [γ-Fe₂O₃@HAp-Si(CH₂)₃Cl@DMIM] in short reaction times (7-13 min) and high to excellent yields (80%-95%). Cleaner reaction profile, mild reaction conditions, use of the green solvent, and reusability of the catalyst make this protocol attractive for the large scale synthesis of pyrido[2,3-d]pyrimidine-6-carbonitrile derivatives I and are amenable for iterative combinatorial library generation. The synthesized nanoparticles were characterized by Fourier transform IR spectroscopy, X-ray diffraction, scanning electron microscope, energy dispersive anal. of X-rays, thermogravimetric anal., differential thermogravimetric and vibrating sample magnetometer.

Application In Synthesis of 1739-84-0, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Category: imidazoles-derivatives.

Rao, Anil H. N.;Murthy Shekhar, S.;Halashankar Swamy, M. H.;Pranava, H. K.;Kushal, P. research published 《 Understanding the alkaline stability of imidazolium and benzimidazolium functionalized poly(phenylene oxide) based hydroxide exchange membranes》, the research content is summarized as follows. The imidazolium and benzimidazolium groups containing poly(phenylene oxide) (PPO) hydroxide exchange membrane were synthesized and characterized. The membranes were cast by solution casting method yielding transparent, flexible, and rigid membranes. The phys. properties of the membrane, such as ion exchange capacity (IEC), water absorption, and swelling behavior, were investigated. A comparative study of imidazolium and benzimidazolium functionalized PPO membrane focusing on hydroxide conductivity, and alk. stability was comprehensively examined The C2 substituted Me imidazolium membrane displayed unique morphol. and conductivity of 15 mSCm-1 at 25°C. Due to the sterically protected Me group at the C2 position, imidazolium functionalized PPO membrane showed higher alk. stability for 700 h. Furthermore, benzimidazolium cations would be more easily attacked by a nucleophile (OH-) than imidazolium cations, resulting in ring-opening of the heterocyclic ring.

Category: imidazoles-derivatives, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Product Details of C5H8N2.

Ravula, Sudhir;O’Harra, Kathryn E.;Watson, Keith A.;Bara, Jason E. research published 《 Poly(ionic liquid)s with Dicationic Pendants as Gas Separation Membranes》, the research content is summarized as follows. Poly(norbornene)s and poly(ionic liquid)s are two different classes of attractive materials, which are known for their structural tunability and thermal stabilities, and have been extensively studied as gas separation membranes. The incorporation of ionic liquids (ILs) into the poly(norbornene) through post-polymerization has resulted in unique materials with synergistic properties. However, direct polymerization of norbornene-containing IL monomers as gas separation membranes are limited. Subsequently, the poly(NBM-mIm) with bistriflimide [Tf₂N^–] and poly([NBM-DILs][Tf₂N]₂) comprising homo-, random-, and block- (co)polymers were synthesized via ring-opening metathesis polymerization using the air-stable Grubbs second-generation catalyst. Block copolymers (BCPs), specifically, [NBM-mIM][Tf₂N] and [NBM-ImCnmIm] [Tf₂N]₂ (n = 4 and 6) were synthesized at two different compositions, which generated high mol. weight polymers with decent solubility relative to homo- and random (co)polymers of [NBM-DILs] [Tf₂N]₂. The prepared BCPs were efficiently analyzed by a host of anal. tools, including ¹H-NMR, GPC, and WAXD. The successfully BCPs were cast into thin membranes ranging from 47 to 125μm and their gas (CO₂, N₂, CH₄, and H₂) permeations were measured at 20°C using a time-lag apparatus These membranes displayed modest CO₂ permeability in a non-linear fashion with respect to composition and a reverse trend in CO₂/N₂ permselectivity was observed, as a usual trade-off behavior between permeability and permselectivity.

Product Details of C5H8N2, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Application In Synthesis of 10111-08-7.

Regnault, Romain;Kouach, Mostafa;Goossens, Laurence;Thuru, Xavier;Bailly, Christian;Goossens, Jean-Francois research published 《 Mono- and bis-edaravone adducts formed in the presence of vanillin in an aqueous solution》, the research content is summarized as follows. Edaravone (EDA) is an antioxidant drug used for the treatment of amyotrophic lateral sclerosis. Edaravone has been shown to react with aldehydes, such as 6-formylpterin. We investigated the reaction of edaravone with vanillin (used as a model aromatic aldehyde) to evidence the reaction products formed in an aqueous solution Mono- and bis-adducts vanillin-(edaravone)_1-2 were characterized by high-performance liquid chromatog. coupled to high-resolution mass spectrometry. Kinetic anal. revealed that the bis-adduct vanillin-(edaravone)₂ formed more intensely and more rapidly than the mono-adduct vanillin-(edaravone)₁. Decay rates of 2.4μM/min and 3.4μM/min were calculated for vanillin and edaravone, resp. The Michael addition of a second edaravone mol. onto the vanillin-(edaravone)1 hybrid corresponds to a facile reaction compared to the initial Knoevenagel-type condensation between edaravone and vanillin. However, the bis-adduct vanillin-(edaravone)₂ can decompose in solution to provide the mono-adduct and regenerate small amounts of edaravone and vanillin. The regeneration of vanillin from vanillin-(edaravone)₂ was kinetically characterized. We compared the condensation of edaravone with fifteen aromatic aldehydes, to show that only vanillin and 3-methoxy-benzaldehyde can react easily with edaravone, the other aromatic aldehydes being less or not reactive. The study opens perspectives to apprehend the reactivity of edaravone with biol. relevant aldehydes.

Application In Synthesis of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Electric Literature of 10111-08-7.

Rha, Chang Joo;Lee, Hangyul;Kim, Cheal research published 《 An effective phthalazine-imidazole-based chemosensor for detecting Cu²⁺, Co²⁺ and S^2- via the color change》, the research content is summarized as follows. A novel and effective phthalazine-imidazole-based colorimetric chemosensor (E)-1-(2-((1H-imidazol-2-yl)methylene)hydrazinyl)phthalazine NNI was synthesized and tested to detect Cu²⁺ or Co²⁺ ions in buffer solution NNI could probe Cu²⁺ and Co²⁺ by the color change from colorless to yellow. The complexation stoichiometries of NNI toward Cu²⁺ and Co²⁺ were, resp., confirmed to be as 1:1 ratio and 2:1 by results of Job plot and ESI-mass. Detection limits of NNI for each metal showed 0.12 μM and 65 nM which are lower than WHO guideline (31.5 μM for Cu²⁺) and US Environmental Protection Agency (EPA) guideline (1.7 μM for Co²⁺). Quantification of NNI for each metal was successful in real water samples. The Cu²⁺-NNI complex could detect S^2- by demetallation with color change from yellow to colorless, and detection limit for S^2- was determined as 0.80 μM, which is lower than WHO guideline (14.8 μM). Cu²⁺-NNI could detect S^2- without interference when other anions coexisted. Detection of Cu²⁺, Co²⁺ and S^2- among various metal ions and anions was successfully confirmed using test papers stained with NNI and Cu²⁺-NNI. Sensing processes of Cu²⁺, Co²⁺ and S^2- by NNI were elucidated by UV-vis titration, ESI-mass, FT-IR, ¹H NMR titration and DFT calculations

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Electric Literature of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Recommanded Product: Imidazole-4-carbaldehyde.

Robles, Omar;Jackson, Jeffrey J.;Marshall, Lisa;Talay, Oezcan;Chian, David;Cutler, Gene;Diokno, Raymond;Hu, Dennis X.;Jacobson, Scott;Karbarz, Emily;Kassner, Paul D.;Ketcham, John M.;McKinnell, Jenny;Meleza, Cesar;Reilly, Maureen K.;Riegler, Erin;Shunatona, Hunter P.;Wadsworth, Angela;Younai, Ashkaan;Brockstedt, Dirk G.;Wustrow, David J.;Zibinsky, Mikhail research published 《 Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors》, the research content is summarized as follows. The C-C chemokine receptor 4 (CCR4) is broadly expressed on regulatory T cells (T_reg) as well as other circulating and tissue-resident T cells. T_reg can be recruited to the tumor microenvironment (TME) through the C-C chemokines CCL17 and CCL22. T_reg accumulation in the TME has been shown to dampen the antitumor immune response and is thought to be an important driver in tumor immune evasion. Preclin. and clin. data suggest that reducing the T_reg population in the TME can potentiate the antitumor immune response of checkpoint inhibitors. We have developed small-mol. antagonists of CCR4, featuring a novel piperidinyl-azetidine motif, that inhibit the recruitment of T_reg into the TME and elicit antitumor responses as a single agent or in combination with an immune checkpoint blockade. The discovery of these potent, selective, and orally bioavailable CCR4 antagonists(I), and their activity in in vitro and in vivo models, is described herein.

Recommanded Product: Imidazole-4-carbaldehyde, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, 3034-50-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Application In Synthesis of 10111-08-7.

Rubin-Osanz, Marcos;Lambert, Francois;Shao, Feng;Riviere, Eric;Guillot, Regis;Suaud, Nicolas;Guihery, Nathalie;Zueco, David;Barra, Anne-Laure;Mallah, Talal;Luis, Fernando research published 《 Chemical tuning of spin clock transitions in molecular monomers based on nuclear spin-free Ni(II)》, the research content is summarized as follows. We report the existence of a sizeable quantum tunnelling splitting between the two lowest electronic spin levels of mononuclear Ni complexes. The level anti-crossing, or magnetic “clock transition”, associated with this gap has been directly monitored by heat capacity experiments The comparison of these results with those obtained for a Co derivative, for which tunnelling is forbidden by symmetry, shows that the clock transition leads to an effective suppression of intermol. spin-spin interactions. In addition, we show that the quantum tunnelling splitting admits a chem. tuning via the modification of the ligand shell that determines the crystal field and the magnetic anisotropy. These properties are crucial to realize model spin qubits that combine the necessary resilience against decoherence, a proper interfacing with other qubits and with the control circuitry and the ability to initialize them by cooling.

Application In Synthesis of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Recommanded Product: 1,2-Dimethyl-1H-imidazole.

Sahm, Constantin D.;Mates-Torres, Eric;Eliasson, Nora;Sokolowski, Kamil;Wagner, Andreas;Dalle, Kristian E.;Huang, Zehuan;Scherman, Oren A.;Hammarstrom, Leif;Garcia-Melchor, Max;Reisner, Erwin research published 《 Imidazolium-modification enhances photocatalytic CO₂ reduction on ZnSe quantum dots》, the research content is summarized as follows. Colloidal photocatalysts can utilize solar light for the conversion of CO₂ to carbon-based fuels, but controlling the product selectivity for CO₂ reduction remains challenging, in particular in aqueous solution Here, we present an organic surface modification strategy to tune the product selectivity of colloidal ZnSe quantum dots (QDs) towards photocatalytic CO₂ reduction even in the absence of transition metal co-catalysts. Besides H₂, imidazolium-modified ZnSe QDs evolve up to 2.4 mmol_CO g_ZnSe^-1 (TON_QD > 370) after 10 h of visible light irradiation (AM 1.5G, λ > 400 nm) in aqueous ascorbate solution with a CO-selectivity of up to 20%. This represents a four-fold increase in CO-formation yield and 13-fold increase in CO-selectivity compared to non-functionalized ZnSe QDs. The binding of the thiolated imidazolium ligand to the QD surface is characterized quant. using ¹H-NMR spectroscopy and isothermal titration calorimetry, revealing that a subset of 12 to 17 ligands interacts strongly with the QDs. Transient absorption spectroscopy reveals an influence of the ligand on the intrinsic charge carrier dynamics through passivating Zn surface sites. D. functional theory calculations indicate that the imidazolium capping ligand plays a key role in stabilizing the surface-bound *CO₂^– intermediate, increasing the yield and selectivity toward CO production Overall, this work unveils a powerful tool of using organic capping ligands to modify the chem. environment on colloids, thus enabling control over the product selectivity within photocatalyzed CO₂ reduction

Recommanded Product: 1,2-Dimethyl-1H-imidazole, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Application In Synthesis of 10111-08-7.

Salomon-Santiago, Carmen;Perdomo, Gaston;Flores-Segura, Henoc;Notario, Rafael;Orozco-Guareno, E. research published 《 Experimental and theoretical thermochemical studies of imidazole, imidazole-2-carboxaldehyde and 2-aminobenzimidazole》, the research content is summarized as follows. Here were determined the molar standard enthalpies of formation, ΔfH°m (s), at T = 298.15 K of imidazole, imidazole-2-carboxaldehyde and 2-aminobenzimidazole from their resp. molar standard energies of combustion, obtained by static combustion calorimetry. Enthalpies of sublimation, ΔgsH°m, at T = 298.15 K were obtained by thermogravimetry measurements. Using data for ΔfH°m (s) and ΔgsH°m , the gas phase enthalpies of the two imidazole-derived compounds were calculated The enthalpy increases due to certain functional groups attached to the imidazole (IM) mol., and were analyzed that change in the enthalpies using the exptl. gas phase enthalpy of formation data. By using theor. methods, namely G3 and G4, the enthalpies of formation of the compounds under study were obtained and were compared with the exptl. ones. In addition, the purity, the melting temperature, the enthalpy of fusion and the heat capacity of the compounds were determined by differential scanning calorimetry.

Application In Synthesis of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Application of C4H4N2O.

Pan, Yong;Yu, Xi research published 《 Preparation of Zeolitic Imidazolate Framework-91 and its modeling for pervaporation separation of water/ethanol mixtures》, the research content is summarized as follows. Zeolitic Imidazolate Framework (ZIFs) have received much attention in recent years because of their good compatibility with polymer, and their ultramicroporosities that are in the range of the kinetic diameter of several important gas and liquid mols. In this study, three different ZIF particles, i.e., ZIF-90 and its derivatives (ZIF-91 and ZIF-92) were synthesized and incorporated into polydimethylsiloxane (PDMS) matrix to fabricate ZIF/PDMS nanocomposite membrane for pervaporation recovery of ethanol. The morphologies and structures of ZIF particles and their nanocomposite membrane were characterized by various techniques. The results show that ZIF-91 particles with hydroxyl functional groups have good compatibility with PDMS and are dispersed well in PDMS matrix. Meanwhile, ZIF-91/PDMS nanocomposite membrane have higher pervaporation performance compared to ZIF-90/PDMS and ZIF-92/PDMS nanocomposite membrane with the same loading of 20 weight%. The effects of particle loading, feed concentration and temperature on the separation performance of ZIF-91/PDMS membranes were also investigated. The results indicate that ZIF-91/PDMS-20 weight% membrane showed a prominent separation factor of 15.8 at 55°C with a comparable total flux of 846 g/(m² h), which were higher than that of pure PDMS (4.1, 496 g/(m² h)). In addition, the pervaporation modeling for the flux and separation factor of ZIF-91/PDMS membrane were established with quadratic equations of temperature and feed concentration, which can be used to predict separation performance according to the experiment conditions.

Application of C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem