Tag: M.W=50-100

Imidazole based anticancer drug find applications in cancer chemotherapy. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Safety of Imidazole-4-carbaldehyde.

Osmaniye, Derya;Karaca, Sevval;Kurban, Berkant;Baysal, Merve;Ahmad, Iqrar;Patel, Harun;Ozkay, Yusuf;Asim Kaplancikli, Zafer research published 《 Design, synthesis, molecular docking and molecular dynamics studies of novel triazolothiadiazine derivatives containing furan or thiophene rings as anticancer agents》, the research content is summarized as follows. In this study, new triazolothiadiazine derivatives I [X = O, S; R = H, Me, MeO, Cl; R¹ = H, Cl; R² = H, Me, MeO, etc.] were synthesized and their anticancer activities were investigated. Compounds I [X = O, R = R² = Cl, R¹ = H; X = S, R = H, Cl, R¹ = H, R² = Cl] showed inhibitor activity against MCF-7 cell line with IC₅₀ = 4.63 ± 0.10; 2.23 ± 0.16; 3.13 ± 0.08μM value, resp. As a result of in-vitro aromatase enzyme inhibition test, compound I [X = S, R = R¹ = H, R² = Cl] was the most active derivative with IC₅₀ = 0.058 ± 0.023μM. In addition, DNA synthesis inhibition percentages of the compounds I were measured by the BrdU method. The intermol. interactions of the promising compounds I with aromatase enzyme were investigated through the SP docking approach, which revealed significant binding interaction energies associated with these compounds Following that, the interaction’s stability was assessed using a typical atomistic 100 ns dynamic simulation study. A number of parameters derived from MD simulation trajectories were computed and validated for the protein-ligand complex’s stability under the dynamic conditions.

3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, Safety of Imidazole-4-carbaldehyde

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Synthetic Route of 10111-08-7.

Pan, Lei;Jin, Feng;Fu, Rui;Gao, Ke;Zhou, Shaofang;Bao, Xiaoguang research published 《 Oxidative Ring-Opening of 1H-Pyrazol-5-amines and Its Application in Constructing Pyrazolo-Pyrrolo-Pyrazine Scaffolds by Domino Cyclization》, the research content is summarized as follows. Herein, an oxidative ring-opening of 1H-pyrazol-5-amines to form 3-diazenylacrylonitrile derivatives under mild and transition-metal-free conditions is described. In addition, the nucleophilic addition of deprotonated 1H-pyrrole-2-carbaldehydes to the vinyl moiety of the yielded 3-diazenylacrylonitriles could trigger domino cyclization to afford the 3H-pyrazolo[3,4-e]pyrrolo[1,2-a]pyrazine derivatives Computational studies suggest that the oxidation of 1H-pyrazol-5-amines in the presence of PhIO is through the formation of a hydroxylamine intermediate followed by elimination of H₂O to result in the ring-opening product. The detailed domino cyclization pathway leading to the pyrazolo-pyrrolo-pyrazine scaffolds is revealed.

Synthetic Route of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Reference of 10111-08-7.

Pan, Yong;Xie, Rui;Xu, BaoMing;Chen, Chi research published 《 Determination of sorption and diffusion for ethanol through superhydrophobic ZIF/PDMS mixed matrix membrane》, the research content is summarized as follows. The hydrophobicity-hydrophilicity properties of the surface play decisive roles in the resultant separation performance of the membrane, especially the hydrophobicity of mixed matrix membranes (MMMs) for pervaporation recovery of various organic systems from aqueous solution Herein, superhydrophobic Zeolitic Imidazolate Framework-90 (S-ZIF-90) was employed as filler to incorporate into Polydimethylsiloxane (PDMS) to prepare superhydrophobic S-ZIF-90/PDMS MMMs for ethanol permselective pervaporation. The chem. structures and superhydrophobicity properties of the surface of S-ZIF-90 and S-ZIF-90/PDMS MMMs were demonstrated by various characterization techniques. The results showed that S-ZIF-90 particles and S-ZIF-90/PDMS composite membranes were successfully prepared and S-ZIF-90/PDMS MMMs have higher hydrophobicity property as compared to ZIF-90/PDMS MMMs or pure PDMS. Therefore, S-ZIF-90/PDMS MMMs showed more excellent separation performance than ZIF-90/PDMS MMMs or pure PDMS. In particular, S-ZIF-90/PDMS MMMs with 15 wt% S-ZIF-90 loading have a total flux of 1064 g/(m² h) with a maximum separation factor of 14.9 at 40°C for 5 wt% dilute ethanol solution The diffusion coefficients, permeation coefficients, adsorption heat and adsorption entropy of ethanol and water were also calculated by sorption tests, which might provide a method to further determinate the mass transfer mechanism of MMMs in pervaporation process.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Reference of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Synthetic Route of 3034-50-2.

Martin-Acosta, Pedro;Amesty, Angel;Guerra-Rodriguez, Miguel;Guerra, Borja;Fernandez-Perez, Leandro;Estevez-Braun, Ana research published 《 Modular Synthesis and Antiproliferative Activity of New Dihydro-1H-pyrazolo[1,3-b]pyridine Embelin Derivatives》, the research content is summarized as follows. A set of new dihydro-1H-pyrazolo[1,3-b]pyridine I [R¹ = Et Ph, 4-pyridyl, etc.; R² = Me, 2-furanyl, Ph, etc.; R³ = Et, Bu, undecyl, etc.] . was synthesized through a multicomponent reaction from natural embelin, 3-substituted-5-aminopyrazoles and aldehydes. The synthesized compounds I were evaluated against three hematol. tumor cell lines, HEL (acute erythroid leukemia), K-562 (chronic myeloid leukemia) and HL-60 (acute myeloid leukemia), and five breast cancer cell lines (SKBR3, MCF-7, MDA-MB-231, BT-549, HS-578T). The primate non-malignant kidney Vero cell line was used as the control of cytotoxicity. From the obtained results, some structure-activity relationships were outlined. Furthermore, in silico prediction of physicochem. properties and ADME parameters were determined for the derivatives with the best antiproliferative values.

Synthetic Route of 3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, 3034-50-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Recommanded Product: 1H-Imidazole-2-carbaldehyde.

Martins-Costa, Marilia T. C.;Anglada, Josep M.;Francisco, Joseph S.;Ruiz-Lopez, Manuel F. research published 《 Photosensitization mechanisms at the air-water interface of aqueous aerosols》, the research content is summarized as follows. Photosensitization reactions are believed to provide a key contribution to the overall oxidation chem. of the Earth s atm. Generally, these processes take place on the surface of aqueous aerosols, where organic surfactants accumulate and react, either directly or indirectly, with the activated photosensitizer. However, the mechanisms involved in these important interfacial phenomena are still poorly known. This work sheds light on the reaction mechanisms of the photosensitizer imidazole-2-carboxaldehyde through ab initio (QM/MM) mol. dynamics simulations and high-level ab initio calculations The nature of the lowest excited states of the system (singlets and triplets) is described in detail for the first time in the gas phase, in bulk water, and at the air-water interface, and possible intersystem crossing mechanisms leading to the reactive triplet state are analyzed. Moreover, the reactive triplet state is shown to be unstable at the air-water surface in a pure water aerosol. The combination of this finding with the results obtained for simple surfactant-photosensitizer models, together with exptl. data from the literature, suggests that photosensitization reactions assisted by imidazole-2-carboxaldehyde at the surface of aqueous droplets can only occur in the presence of surfactant species, such as fatty acids, that stabilize the photoactivated triplet at the interface. These findings should help the interpretation of field measurements and the design of new laboratory experiments to better understand atm. photosensitization processes.

Recommanded Product: 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Formula: C4H4N2O.

Mas Claret, Eduard;Al Yahyaei, Balqees;Chu, Shuyu;Elliott, Ruan M.;Imperato, Manuel;Lopez, Arnaud;Meira, Lisiane B.;Howlin, Brendan J.;Whelligan, Daniel K. research published 《 An aza-nucleoside, fragment-like inhibitor of the DNA repair enzyme alkyladenine glycosylase (AAG)》, the research content is summarized as follows. The DNA repair enzyme AAG has been shown in mice to promote tissue necrosis in response to ischemic reperfusion or treatment with alkylating agents. A chem. probe inhibitor is required for investigations of the biol. mechanism causing this phenomenon and as a lead for drugs that are potentially protective against tissue damage from organ failure and transplantation, and alkylative chemotherapy. Herein, we describe the rationale behind the choice of arylmethylpyrrolidines as appropriate aza-nucleoside mimics for an inhibitor followed by their synthesis and the first use of a microplate-based assay for quantification of their inhibition of AAG. We finally report the discovery of an imidazol-4-ylmethylpyrrolidine as a fragment-sized, weak inhibitor of AAG.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Formula: C4H4N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Application In Synthesis of 3034-50-2.

Mas Claret, Eduard;Al Yahyaei, Balqees;Chu, Shuyu;Elliott, Ruan M.;Imperato, Manuel;Lopez, Arnaud;Meira, Lisiane B.;Howlin, Brendan J.;Whelligan, Daniel K. research published 《 An aza-nucleoside, fragment-like inhibitor of the DNA repair enzyme alkyladenine glycosylase (AAG)》, the research content is summarized as follows. The DNA repair enzyme AAG has been shown in mice to promote tissue necrosis in response to ischemic reperfusion or treatment with alkylating agents. A chem. probe inhibitor is required for investigations of the biol. mechanism causing this phenomenon and as a lead for drugs that are potentially protective against tissue damage from organ failure and transplantation, and alkylative chemotherapy. Herein, we describe the rationale behind the choice of arylmethylpyrrolidines as appropriate aza-nucleoside mimics for an inhibitor followed by their synthesis and the first use of a microplate-based assay for quantification of their inhibition of AAG. We finally report the discovery of an imidazol-4-ylmethylpyrrolidine as a fragment-sized, weak inhibitor of AAG.

Application In Synthesis of 3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, 3034-50-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Category: imidazoles-derivatives.

Masek, Anna;Cichosz, Stefan research published 《 Biocomposites of epoxidized natural rubber/poly(lactic acid) modified with natural substances: influence of biomolecules on the aging properties (Part II)》, the research content is summarized as follows. The aim of this study is to present the possible influence of natural substances on the aging properties of epoxidized natural rubber (ENR) and poly(lactic acid) (PLA) eco-friendly elastic blends. Therefore, the ENR/PLA blends were filled with natural pro-health substances of potentially antioxidative behavior, namely, δ-tocopherol (vitamin E), curcumin, β-carotene and quercetin. In this way, the material biodeterioration potential was maintained and the material’s lifespan was prolonged while subjected to increased temperatures or high-energy UVA irradiation (340 nm). The investigation of the samples’ properties indicated that curcumin and quercetin are the most promising natural additives that may contribute to the delay of ENR/PLA degradation under the above-mentioned conditions. The efficiency of the proposed new natural anti-aging additives was proven with static mech. anal., color change investigation, as well as mass loss during a certain aging. The aging coefficient, which compares the mech. properties before and after the aging process, indicated that the ENR/PLA performance after 200 h of accelerated aging might decrease only by approx. 30% with the blend loaded with quercetin. This finding paves new opportunities for bio-based and green anti-aging systems employed in polymer technol.

Category: imidazoles-derivatives, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Recommanded Product: 1,2-Dimethyl-1H-imidazole.

Matsumoto, Kozo;Yano, Takuya;Date, Shota;Odahara, Yuka;Narimura, Shingo research published 《 Synthesis of imidazolium-based poly(ionic liquid)s and their application to ion-exchange materials》, the research content is summarized as follows. Linear and networked poly(ionic liquid)s, which were composed of polyoxetanes and imidazolium groups, were synthesized by cationic polymerization of mono- and di- functional oxetanyl monomers, and the properties of the obtained polymers were investigated. The monofunctional monomer, 3-(3-ethyl-3-oxetanylmethyl)-1,2-dimethylimidazolium bis(trifluoromethanesulfonyl)imide (OXDMImTFSI), was prepared from the reaction of 3-ethyl-3-oxetanylmethyl chloride with 1,2-dimethylimidazole followed by exchanging the chloride to bis(trifluonomethanesulfonyl)imide (TFSI). The difunctional monomer, 1,3-di(3-ethyl-3-oxetanylmethyl)-2-methylimidazolium bis(trifluoromethanesulfonyl)imide (DOXMImTFSI), was prepared from the reaction of 3-ethyl-3-oxetanylmethyl chloride with 2-methylimidazole and successive ion-exchange of chloride to TFSI. OXDMImTFSI was polymerized by addition of a catalytic amount of BF₃ di-Et ether complex. The obtained linear polyOXDMImTFSI showed good stability toward heat and basic conditions. Networked polymer films were prepared by homo/co-polymerization of DOXMImTFSI or DOXMImTFSI/OXDMImTFSI liquid layers using the thermally latent cationic initiator, (1-naphthylmethyl) Me p-hydroxyphenyl sulfonium hexafluoroantimonate (SI-60). The obtained films showed good ion-exchange ability between TFSI, Cl, and OH anions.

1739-84-0, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., Recommanded Product: 1,2-Dimethyl-1H-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. HPLC of Formula: 10111-08-7.

McNulty, James;Babu Dokuburra, Chanti;D’Aiuto, Leonardo;Demers, Matthew;McClain, Lora;Piazza, Paolo;Williamson, Kelly;Zheng, Wenxiao;Nimgaonkar, Vishwajit L. research published 《 Synthesis of non-nucleoside anti-viral cyclopropylcarboxacyl hydrazones and initial anti-HSV-1 structure-activity relationship studies》, the research content is summarized as follows. The synthesis of a lead anti-viral cyclopropyl carboxy acyl hydrazone 4F17 and three sequential arrays of structural analogs along with the initial assessment and optimization of the antiviral pharmacophore against the herpes simplex virus type 1 (HSV-1) are reported.

HPLC of Formula: 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem