Tag: M.W=50-100

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Recommanded Product: Imidazole-4-carbaldehyde.

Li, Min-Xin;Pu, Xiao-Jia;Zhang, Xia;Zheng, Xi;Gao, Hui;Xiao, Wei-Lie;Wan, Chun-Ping;Mao, Ze-Wei research published 《 Synthesis and Biological Evaluation of Heterocyclic Substituted Bis(indolyl)methanes》, the research content is summarized as follows. A series of heterocyclic substituted bis(indolyl)methanes I (het = 2-furyl, 3-thienyl, 3-indolyl, etc.) have been prepared by boron trifluoride etherate catalyzed condensation reaction of indole and heterocyclic aldehydes with high yields. Preliminary in vitro anti-inflammatory in lipopolysaccharide (LPS)-stimulated RAW-264.7 macrophages and cytotoxic activity against human tumor cell lines (A549, Hela and SGC7901) by MTT assay were tested. The result indicated that heterocyclic substituted bis(indolyl)methanes showed good antiinflammatory and selective cytotoxic activity. Especially, compounds I (het = 3-indolyl), I (het = 1H-pyrrolo[2,3-b]pyridine-3-yl) and I (het = quinolin-3-yl) displayed similar inhibitory effect on the generation of NO to pos. control dexamethasone, and compound I (het = quinolin-3-yl) displayed similar selective cytotoxic activity to 5-FU. Heterocyclic substituted bis(indolyl)methanes may be used as potential anti-inflammatory and anticancer leads.

Recommanded Product: Imidazole-4-carbaldehyde, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, 3034-50-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Application of C4H4N2O.

Li, Shengnan;Li, Ying;Yan, Bing research published 《 A turn-on fluorescence sensing strategy for rapid detection of flumequine in water environments using covalent-coordination functionalized MOFs》, the research content is summarized as follows. With the high output and large use of antibiotics in the process of aquaculture, pollution caused by antibiotics in water environments is becoming a thorny problem, and its ecol. risk has aroused widespread concern. In this work, the lanthanide hybrid material Eu@ZIF-90-PA is synthesized by a two-step post synthesis strategy using ZIF-90 with a modifiable group as a parent skeleton. Owing to its luminescence properties and water stability, the lanthanide functionalized material can be utilized as a novel “turn-on” fluorescent probe for quant. detection of flumequine in water environments. Addnl., the probe can not only be reused, but also quickly respond to flumequine within 30 s and the detection limit is 0.24 ppm. Even in the complex river water, the probe still exhibits an obvious luminescence enhancement effect with flumequine, which provides an efficient and convenient method for the detection of flumequine in real water. Finally, the fluorescence enhancement mechanism between flumequine and the probe is further explored.

Application of C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Related Products of 10111-08-7.

Li, Wenjun;Chen, Siyu;Yang, Yue;Song, Yiju;Ma, Chaoyun;Qiao, Xiuwen;Hong, Chenglin research published 《 Ultrasensitive electrochemical immunosensor based on the signal amplification strategy of the competitive reaction of Zn²⁺ and ATP ions to construct a “signal on” mode GOx-HRP enzyme cascade reaction》, the research content is summarized as follows. A GOx/HRP@ZIF-90 nanomaterial is proposed by coating GOx and HRP in ZIF-90 using a bio-simulated mineralization method to improve the tolerance of the enzyme to the external environment. In the detection process, the ZIF-90 is turned on under mild conditions by the competitive reaction of ATP with Zn2+ and imidazole-2-carboxaldehyde (2-ICA), and the elec. signal of the system is amplified by the enzyme cascade reaction of GOx and HRP. Finally, based on the signal amplification strategy of the competitive reaction between Zn2+ and ATP to construct a “signal on” mode, electrochem. immunosensor of GOx-HRP enzyme-linked cascade reaction was prepared The proposed electrochem. immunosensor shows an excellent anal. performance when detecting CA-125, with good selectivity and stability, with a detection range of 0.1 pg mL-1-40 ng mL-1 and a detection limit of 0.05 pg mL-1. The test has been performed using chronoamperometry under a constant voltage of -0.4 V. The immunosensor also shows an excellent performance when analyzing human blood samples. The recovery of the immunosensor is 97.94-101.8%, with a relative standard deviation of 3.7-6.1%. The proposed sensor provides a novel idea for clin. use of GOx and HRP enzymes and a new method for the clin. detection of tumor markers.

Related Products of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). SDS of cas: 10111-08-7.

Li, Xinyi;Hou, Shengxin;Chen, Jiucun;He, Cai-E.;Gao, Yong-E.;Lu, Yi;Jia, Die;Ma, Xianbin;Xue, Peng;Kang, Yuejun;Xu, Zhigang research published 《 Engineering silk sericin decorated zeolitic imidazolate framework-8 nanoplatform to enhance chemotherapy》, the research content is summarized as follows. The low therapeutic effect and strong side-effect are the major barriers for clin. chemotherapy. Herein, a pH-responsive nanoplatform based-silk sericin-zeolitic imidazolate framework-8 was designed for the delivery of chemotherapeutic doxorubicin (denoted as ZIF-8@DOX@SS, ZDS), which can overcome the limitation of poor circulation stability and unexpected drug leakage in blood circulation, producing a satisfactory chemotherapy. Concretely, ZIF-8 structure shows better stability and biocompatibility owing to the protection of a nature and non-toxic sericin protein. When it comes to low pH environment (e.g. in tumor cell microenvironment), the coordination effect in ZIF-8 will be broken and release DOX drugs. The nano-sized morphol. endow ZDS an efficient drug uptake and significant tumor permeability efficiency. Furthermore, the tumor-specific biodegradability makes ZDS possible to realize targeted and enhanced chemotherapy. Considering all the advantages in the study, this silk sericin-based nanosystem represent a promising strategy for the design of stimuli-responsive by using natural polymer to improve the treatment effect of chemotherapy.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., SDS of cas: 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Application of C4H4N2O.

Li, Yang-Yang;Li, Shuai;Fan, Tao;Zhang, Zi-Jing;Song, Jin;Gong, Liu-Zhu research published 《 Enantioselective Formal [4 + 3] Annulations to Access Benzodiazepinones and Benzoxazepinones via NHC/Ir/Urea Catalysis》, the research content is summarized as follows. A robust and scalable formal [4 + 3] annulation reaction for the synthesis of optically pure 1,4-benzodiazepinones and 1,4-benzoxazepinones has been established by a combined catalytic system consisting of a chiral NHC, a chiral Ir/phosphine-olefin complex, and an achiral urea, enabling the asym. synthesis of a selective inhibitor of mitochondrial F₁F₀ ATP hydrolase.

3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, Application of C4H4N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Recommanded Product: 1,2-Dimethyl-1H-imidazole.

Li, Yuqing;Bi, Qiang;Cheng, Wen;Zhang, Zekun;Guo, Yinyin;Ren, Kang;Xue, Juanqin research published 《 Experimental study on the synergistic effect between novel imidazoline hexafluorophosphate ionic liquid with KI on mild steel in 1M H2SO4》, the research content is summarized as follows. In this paper, the corrosion inhibition performance of [C16DMIM] [PF₆] ionic liquid on mild steel in 1M H₂SO₄ environment and the corrosion inhibition performance and mechanism of [C16DMIM] [PF₆] compounded with KI, thiourea and formaldehyde, resp., were investigated based on serious corrosion hazards of metal pickling. The inhibition ability of [C16DMIM] [PF₆] was evaluated by static weight loss method, electrochem. corrosion testing and microscopic morphol. anal., while the synergistic effect of the ionic liquid compounded with KI, thiourea and formaldehyde was explored by experiments and quantum chem. calculations(QC). The static weight loss results showed that the addition of 20 mg/L [C16DMIM] [PF₆] could achieve 80.1% inhibition efficiency, and the combination of 20 mg/L KI could achieve 95.9% efficiency and maintain 94.1% efficiency after 7h. The electrochem. results showed that both [C16DMIM] [PF₆] and the compounded corrosion inhibitor showed a mixed inhibition mode, and the impedance test revealed that the corrosion inhibitor formed a double elec. layer to reduce corrosion through the charge transfer process. SEM (SEM) observed that the surface of the mild steel was smooth and the corrosion depth was reduced after the effect of the compound corrosion inhibitor. The synergistic effect of ILs and KI is optimal. The synergistic mechanism is that I- preferentially adsorbs on the surface to form a bridge and thus attracts the protonated [C16DMIM] [PF₆] for adsorption, which in turn enhances the strength of the adsorbed film and makes the protective film denser.

Recommanded Product: 1,2-Dimethyl-1H-imidazole, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Formula: C4H4N2O.

Li, Zhengyi;Li, Hu;Yang, Song research published 《 Carboxylate-Functionalized Zeolitic Imidazolate Framework Enables Catalytic N-Formylation Using Ambient CO₂》, the research content is summarized as follows. In this work, carboxylate-functionalized zeolitic imidazolate framework (F-ZIF-90) with good crystallinity and porosity was constructed from ZIF-90 and employed as a robust heterogeneous catalyst to boost the reductive N-functionalization of various amines with CO₂ to furnish N-formyl compounds (up to 99% yield) in the presence of PhSiH3 under an ambient environment. The imidazole carboxylate species (COO-) can not only activate hydrosilane and CO₂ to form the key intermediate formoxysilane but also activate amines to participate in the N-formylation reaction to obtain the target product. Moreover, it can enhance the catalyst capture and exchange ability toward ambient CO₂. The powerful adsorption capacity of the F-ZIF-90 catalyst toward CO₂ was conducive to elevating CO₂ concentration around the active species. Theor. calculations showed that the carboxylate-mediated conversion path undergoes the transition state of hydrosilane activation with a relatively lower energy barrier (ΔG = 26.9 kcal mol^-1). F-ZIF-90 exhibited good thermochem. stability with no obvious activity attenuation after repeated use 5 times. This strategy opens a new avenue based on ZIFs to develop heterogeneous catalysts for reductive upgrading of CO₂.

Formula: C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Related Products of 10111-08-7.

Krishnaveni, T.;Lakshmi, K.;Kaveri, M. V.;Kadirvelu, K. research published 《 Chemoselective transfer hydrogenation of aromatic and heterocyclic aldehydes by green chemically prepared cobalt oxide nanoparticles》, the research content is summarized as follows. A new surfactant (quercetin) assisted hydrothermal method was used for the preparation of phase pure cobalt oxide (Co₃O₄) nanoparticles (Nps). The quercetin acted well as surfactant in producing size controlled Nps. The produced Nps were extensively characterized by various techniques to reveal its chem. composition, structure, morphol., size and thermal behavior. The main objective of the study was to employ the prepared material as heterogeneous catalyst for hydrogenation of therapeutically important aldehydes. The capability of the catalyst was appear to be good, since the yield of alcs. from structurally different aldehydes is adequate with short period of time. Also the catalyst was recyclable, stable, no need of addition of ligands for activation and environmentally benign.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Related Products of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Application In Synthesis of 10111-08-7.

Kumar, Gautam;Goutami Godavari, Ambati;Tambat, Rushikesh;Kumar, Siva;Nandanwar, Hemraj;Elizabeth Sobhia, M.;Jachak, Sanjay M. research published 《 Synthesis, biological evaluation and computational studies of acrylohydrazide derivatives as potential Staphylococcus aureus NorA efflux pump inhibitors》, the research content is summarized as follows. The NorA efflux pump decreases the intracellular concentration of fluoroquinolones (ciprofloxacin, norfloxacin) by effluxing them from Staphylococcus aureus cells. The synthesis of novel acrylohydrazides I [R¹ = 2-furyl, 5-nitro-2-furyl, 4-(PhCH₂O)C₆H₄, 3,4,5-(MeO)₃C₆H₂; R² = 4-FC₆H₄, 4-pyridyl, 2-imidazolyl, 5-bromo-2-thienyl, 2-pyrrolyl, etc.] was achieved using well-known reactions, and the products were characterized by various spectroscopy techniques. The synthesized 50 compounds I were evaluated for the NorA efflux pump inhibition activity against S. aureus SA-1199B (norA++) and K1758 (norA-) strains. The study provided two most active compounds viz. I (R¹ = 2-furyl; R² = 5-bromo-2-furyl) and I [R¹ = 3,4,5-(MeO)₃C₆H₂; R² = 2-pyrrolyl]. The compound I (R¹ = 2-furyl; R² = 5-bromo-2-furyl) was found to be the most active in potentiating effect of norfloxacin and it also showed enhanced uptake, efflux inhibition in ethidium bromide assay. Furthermore, this compound also enhanced post antibiotic effect and reduced mutation prevention concentration of norfloxacin. The homol. modeling study was performed to elucidate three-dimensional structure of NorA. Docking studies of potent mols. were done to find the binding affinity and interaction with active site residues. Furthermore, all the tested compounds exhibited good ADME and drug-likeness properties in-silico.

Application In Synthesis of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Computed Properties of 1739-84-0.

Kumar, Santosh;Rastogi, Sumit K.;Singh, Akansha;Bharati Ahirwar, Mini;Deshmukh, Milind M.;Sinha, Arun K.;Kumar, Ravindra research published 《 Friedel-Crafts-type Reaction of (Het)Arenes with Aldehydes/Ketones under Acid-Free Conditions using Neutral Ionic Liquid: A Convenient Routes to bis(Indolyl)methanes and Beyond》, the research content is summarized as follows. Acid-free approach has been demonstrated for Friedel-Crafts-type reaction of (het)arenes with carbonyls using neutral ionic liquid (NIL). Methodol. is enabled to afford a densely functionalized bis(indolyl)methanes in good to excellent yields. This conditions is also compatible to the synthesis of 3,3-di(indol-3-yl)indolin-2-ones, bis(4-hydroxycoumarines) and triarylmethanes (total 40 examples; up to 98% yields). Gram-scale reactions and recycling study were carried out to demonstrate the practicality of present methodol. DFT studies illustrate the catalytic cycle involving simultaneous activation of C=O and indole C-H bond by NIL followed by C-C bond formation.

Computed Properties of 1739-84-0, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem