Design of Benzimidazolyl Phosphines Bearing Alterable P,O or P,N-Coordination: Synthesis, Characterization, and Insights into Their Reactivity was written by Wong, Shun Man;Choy, Pui Ying;Zhao, Qingyang;Yuen, On Ying;Yeung, Chung Chiu;So, Chau Ming;Kwong, Fuk Yee. And the article was included in Organometallics in 2021.Name: 1-Methylbenzimidazole This article mentions the following:
A new series of hemilabile benzimidazolyl phosphines is reported. Entities in this ligand family can be easily assembled and prepared on a large scale via a simple one-pot procedure. X-ray crystallog. analyses show that the Pd metal center can coordinate in different fashions, where it relies on the size of the -PR2 group. With the same ligand scaffold, the ligand having a -PCy2 moiety displays better efficiency in expediting aromatic C-C bond-coupling reactions, while the ligand associated with a -PtBu2 group, in contrast, promotes C-N bond-forming reactions. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Name: 1-Methylbenzimidazole).
1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Name: 1-Methylbenzimidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem