Chemoselective iodination of 6-substituted imidazo[1,2-a]pyridine was written by Zhao, Chunshen;Li, Fei;Yang, Shuo;Liu, Li;Huang, Zhuyan;Chai, Huifang. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2018.Computed Properties of C7H5N3O2 This article mentions the following:
3- And 8-Iodoimidazo[1,2-a]pyridines were synthesized from imidazo[1,2-a]pyridines under different substitution conditions. The mol. electrostatic potential calculations were performed to investigate the chemoselectivity of the substitution reaction. The mol. structures of the target compounds were characterized by single crystal X-ray diffraction anal. In the experiment, the researchers used many compounds, for example, 6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3Computed Properties of C7H5N3O2).
6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Computed Properties of C7H5N3O2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem