Category: imidazoles-derivatives

Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline《Spectroscopic evaluation of a novel multi-element sensitive fluorescent probe derived from 2-(2′-phenylbenzamide)benzimidazole: Selective discrimination of Al^3 + and Cd^2 + from their congeners》 was published in 2016. The authors were Dhaka, Gargi;Kaur, Navneet;Singh, Jasvinder, and the article was included in《Inorganic Chemistry Communications》. The author mentioned the following in the article:

A novel fluorescent chemosensor 2-(2′-phenylbenzamide)benzimidazole (2) exhibiting excited-state intramol. proton transfer (ESIPT) process was synthesized by condensation approach, among which 2 could be used as a multielement sensitive fluorescent probe for both Al^3 + and Cd^2 +. The emission wavelength of 2 underwent blue shift of 78 nm upon binding with these ions. The cation-induced inhibition of ESIPT phenomenon was responsible for these fluorescence changes. Also, the absorption spectra of 2 showed changes with F^– and AcO^– ions also. TD-DFT studies well displayed the blue shift in the emission wavelength of 2 upon binding with Al^3 + ions. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Cerdeira, Ana C.;Leal, Joao P.;Avo, Joao;Viola, Catarina;Casimiro, Maria H.;Ferreira, Luis M.;Paz, Filipe A. A.;Pereira, Laura C. J.;Pereira, Claudia C. L.;Monteiro, Bernardo published 《Multifunctionality of the [C₂mim][Ln(fod)₄] series (Ln = Nd-Tm except Pm): magnetic, luminescence and thermochemical studies》 in 2022. The article was appeared in 《New Journal of Chemistry》. They have made some progress in their research.Recommanded Product: 65039-09-0 The article mentions the following:

A series of nine tetrakis lanthanide β-diketonate complexes of the type [C₂mim][Ln(fod)₄] (C₂mim = 1-ethyl-3-methylimidazolium, fod = 6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionate) were prepared, with yields above 80%, and their thermochem., photophys. and magnetic susceptibilities were evaluated. Thermochem. studies presented a rare and reversible conversion between two solid phases (polymorphism), characteristic of the [Ln(fod)₄]^– anion. Photophys. and magnetic studies revealed that Dy and Er presented the multifunctionality of being simultaneously SMMs and visible (Dy) or near infra-red (Er) emitters. The Nd, Ho and Tm analogs present characteristic emission bands in the NIR region (800-1200 nm), while Sm, Eu, Tb and Dy present emissions in the visible range. Magnetic susceptibility of Tb, Dy, Ho, Er and Tm salts were measured in the temperature range of 2-300 K, showing paramagnetic behavior, although with different regimes, with AC susceptibility measurements, at different frequencies in the range of 10-10 000 Hz, providing evidence of slow magnetic relaxation processes for Gd, Dy and Er analogs with SMM behavior. The experimental procedure involved many compounds, such as 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) .

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a solvent as well as catalyst for the depolymerization of oak wood lignin; a solvent in the hydrolysis of hemicellulose (xylan) to xylose using Brønsted acid catalysts.Recommanded Product: 65039-09-0

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Wang, Yi-Ping;Ou, Xue-Rong;Wang, Yue;Liu, Jian-Quan;Wang, Xiang-Shan published 《A Consecutive Condensation, Cyclization, and Dehydration for the Synthesis of Benzimidazopyrroloquinazolines Catalyzed by TsOH》 in 2018. The article was appeared in 《Journal of Heterocyclic Chemistry》. They have made some progress in their research.Recommanded Product: 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:

A consecutive condensation, cyclization, and dehydration of 2-(1H-benzo[d]imidazol-2-yl)anilines and ketonic acid in toluene catalyzed by TsOH gave a series of benzo[4,5]imidazo[1,2-c]pyrrolo[1,2-a]quinazolin-3(2H)-one derivatives, e.g., I, in good to high yields. The structure of I was further confirmed unambiguously by X-ray diffraction anal. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Recommanded Product: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Recommanded Product: 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride《Influence of Ionic Coordination on the Cathode Reaction Mechanisms of Al/S Batteries》 was published in 2022. The authors were Bhowmik, Arghya;Carrasco-Busturia, David;Jankowski, Piotr;Raccichini, Rinaldo;Garcia-Araez, Nuria;Garcia-Lastra, Juan Maria, and the article was included in《Journal of Physical Chemistry C》. The author mentioned the following in the article:

The lack of knowledge on electrochem. reaction pathways for Al/S batteries prevents the development of practical approaches to mitigate the irreversibility and poor cycling performances of this appealing secondary battery system, which is, in theory, scalable, inexpensive, and energy-dense. Different from the Li/S system, Al/S batteries use ionic liquids (ILs) as electrolytes. The choice of the IL, i.e., whether the IL is based on a conventional EMImCl-based electrolyte or in a deep eutectic mixture of aluminum chloride with urea (or any of its derivatives), strongly affects the electrochem. energy-storage performance of the cell. To shed some light on the Al/S battery chem., here, we present the computational electrochem. research work to determine the most favorable reaction pathways and thermodynamically stable reaction intermediates. We also discuss the effect of the coordination of ionic species (originated from aluminum-containing deep eutectic electrolytes) with polysulfide intermediates, which lead to alterations in the reaction pathway and electrochem. behavior of the Al/S system. The spectroscopic signatures from various reaction intermediates are also reported and validated via comparison with exptl. observations. And 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) was used in the research process.

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a starting material for the preparation of 1-ethyl-3-methylimidazolium chloride/tetrafluoroborate (EMI.Cl.BF4) molten salt for electrochemical studies; a solvent as well as catalyst for the depolymerization of oak wood lignin.Recommanded Product: 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Lohar, Somenath;Maji, Abhishek;Pal, Siddhartha;Mukhopadhyay, Subhra Kanti;Nag, Dipta;Demitri, Nicola;Chattopadhyay, Pabitra published 《Naphthalimide-Based Turn-On Fluorosensor for Aqueous Sulfide Ions for Staining in Living Cells》. The research results were published in《ChemistrySelect》 in 2017.Application In Synthesis of 2-(1H-Benzo[d]imidazol-2-yl)aniline The article conveys some information:

A newly synthesized and characterized naphthalimide derivative (L¹) acts as a highly sensitive chemosensor for aqueous sulfide ions in water/DMSO (3:1, volume/volume) medium as L¹ offers distinctive reactive properties toward aqueous sulfide ions to be converted to L^1A of potential turn-on fluorescent properties over other competitive anions. Gradual addition of aqueous sulfide ions led to the formation of in situ L^1A compound which showed a single point fluorescence enhancement based on intramol. charge transfer (ICT). To establish this new interesting pathway in favor of ICT for sensing sulfide ions, the detailed spectroscopic studies of other three similar type new 1,8-naphthalimide based organic probes (L², L³ and L⁴) duly structurally characterized including theor. (DFT) studies have been carried out systematically. The probe (L¹) detects aqueous sulfide ions as low as 2.4μM in at biol. pH within a very short responsive time (15-20 s) and this non-cytotoxic the probe, L¹ is also useful in acquiring the fluorescent image of the distribution of sulfide ions in living cells using fluorescence microscope. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Application In Synthesis of 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Peng, Hongliang;Huang, Pengru;Yi, Pinggui;Xu, Fen;Sun, Lixian published 《Theoretical studies of π-electron delocalization and localization on intramolecular proton transfer in the ground state》 in 2018. The article was appeared in 《Journal of Molecular Structure》. They have made some progress in their research.Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:

Proton transfer processes of 15 benzimidazole compounds are studied by d. functional theory methods, and natural orbital energy index (NOEI) is introduced. Here, NOEI and nucleus independent chem. shift (NICS) are applied to estimate the π-electron localization and delocalization, resp. Proton transfer potential energy surfaces are calculated to explore these processes, and the results show that the changes of the π-electron delocalization of the Ph (pyridyl) is the main factors for the stability of keto form. There is high correlation between the π-electron delocalization and the proton transfer barrier. When the π-electron localization is considered, the regression increases the correlation coefficient, increasing from 0.9663 to 0.9864. NOEI index is sensitive to π-electron localization; it is a beneficial and useful complement to NICS.2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) were involved in the experimental procedure.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Product Details of 65039-09-0《Ion-permselective conducting polymer-based electrokinetic generators with maximized utility of green water》 was published in 2022. The authors were Yun, Tae Gwang;Bae, Jaehyeong;Nam, Hyeon Gyun;Kim, Dongyeon;Yoon, Ki Ro;Han, Seung Min;Kim, Il-Doo, and the article was included in《Nano Energy》. The author mentioned the following in the article:

Hydro-elec. technol. has gathered much attention by the virtue of water as the energy source. However, the low energy d. of this technol. severely limits its practical use. Here, we demonstrate a PEDOT:PSS-based transpiration-driven electrokinetic power generator (p-TEPG) that enables the utilization of a wider variety of real-world water resources for maximizing energy generation efficiencies. In addition to the conventional elec. double layer on the material surface, the p-TEPG builds an addnl. p.d. in the polymer matrix by the selective penetration of cations into the matrix that contains sulfonate functional groups. p-TEPG exhibits 80-250% higher energy d. than carbon-based TEPG at the same resistance. Moreover, seawater produced enhanced volumetric energy/power densities (34.36 mJ cm^-3 and 44.70μW cm^-3) and areal energy/power densities (410μJ cm^-2 and 0.45μW cm^-2), resp., compared to DI water on a single p-TEPG device, which is sufficient to charge elec. energy storage systems and directly operate low-powered electronic.1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) were involved in the experimental procedure.

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a starting material for the preparation of 1-ethyl-3-methylimidazolium chloride/tetrafluoroborate (EMI.Cl.BF4) molten salt for electrochemical studies; a solvent as well as catalyst for the depolymerization of oak wood lignin.Product Details of 65039-09-0

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Related Products of 65039-09-0《Electrodeposition of a dendrite-free 3D Al anode for improving cycling of an aluminum-graphite battery》 was published in 2022. The authors were Li, Junfeng;Hui, Kwan San;Ji, Shunping;Zha, Chenyang;Yuan, Chengzong;Wu, Shuxing;Bin, Feng;Fan, Xi;Chen, Fuming;Shao, Zongping;Hui, Kwun Nam, and the article was included in《Carbon Energy》. The author mentioned the following in the article:

Aluminum-metal batteries show great potential as next-generation energy storage due to their abundant resources and intrinsic safety. However, the crucial limitations of metallic Al anodes, such as dendrite and corrosion problems in conventional aluminum-metal batteries, remain challenging and elusive. Here, we report a novel electrodeposition strategy to prepare an optimized 3D Al anode on carbon cloth with an uniform deposition morphol., low local c.d., and mitigatory volume change. The sym. cells with the 3D Al anode show superior stable cycling (>450 h) and low-voltage hysteresis (∼170 mV) at 0.5 mA cm^-2. High reversibility (∼99.7%) is achieved for the Al plating/stripping. The graphite | | Al-4/CC full batteries show a long lifespan of 800 cycles with 54 mAh g^-1 capacity at a high c.d. of 1000 mA g^-1, benefiting from the high capacitive-controlled distribution. This study proposes a novel strategy to design 3D Al anodes for metallic-Al-based batteries by eliminating the problems of planar Al anodes and realizing the potential applications of aluminum-graphite batteries.1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) were involved in the experimental procedure.

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a starting material for the preparation of 1-ethyl-3-methylimidazolium chloride/tetrafluoroborate (EMI.Cl.BF4) molten salt for electrochemical studies; a solvent as well as catalyst for the depolymerization of oak wood lignin.Related Products of 65039-09-0

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Masri, Asiah Nusaibah;Sulaimon, Aliyu Adebayo published 《Amino acid-based ionic liquids as dual kinetic-thermodynamic methane hydrate inhibitor》 in 2022. The article was appeared in 《Journal of Molecular Liquids》. They have made some progress in their research.Related Products of 65039-09-0 The article mentions the following:

Three amino acid-based ionic liquids (AAILs) are synthesized to evaluate their performance as inhibitors. They are 1-ethyl-3-methyl-imidazolium-glutamate (EMIMGlu), 1-(3-cyanopropyl)-3-methyl-imidazolium-glutamate (CPMIMGlu) and 1-butyl-3-methyl-imidazolium-glutamate (BMIMGlu). The structures are clarified using NMR. Evaluation of their methane hydrate inhibitor performance is performed by micro-differential scanning calorimeter at 5-15 MPa. As a baseline, the hydrate dissociation in water is also evaluated. A standard correlation of methane hydrate dissociation in water is successfully developed with a low average absolute error. Addnl., the AAILs behave as both thermodn. (THI) and kinetic (KHI) hydrate inhibitors. They simultaneously shift the HLVE curve to a lower temperature and decelerate the hydrate formation by reducing the hydrate nucleation rate. EMIMGlu shows the highest THI performance by producing an average temperature shift of 1.14 K, followed by CPMIMGlu (0.91 K) and BMIMGlu (0.87 K). Furthermore, the addition of the nitrile group in CPMIMGlu IL has enhanced the kinetic inhibition process. The kinetic inhibition performance represented by the relative inhibition power (RIP) decreases in the trend of CPMIMGlu (1.31), EMIMGlu (1.30) and BMIMGlu (0.063). The mechanism of the inhibition is further studied by utilizing COSMO-RS software through σ-profile and σ-potential to understand the inhibition process at the mol. level. The exptl. results and computational studies reveal that AAILs behave as THI and KHI through the existence of four oxygen atoms in their anions and cyano group in the CPMIM cation. Thermodn. inhibition properties of AAILs are found to be influenced by the polarity of AAILs while the kinetic inhibition properties of AAILs are found to be influenced by the hydrogen-bonding acceptor value of the AAILs.1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) were involved in the experimental procedure.

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a solvent as well as catalyst for the depolymerization of oak wood lignin; a solvent in the hydrolysis of hemicellulose (xylan) to xylose using Brønsted acid catalysts.Related Products of 65039-09-0

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Donthiboina, Kavitha;Anchi, Pratibha;Gurram, Sowmyasree;Sai Mani, Geeta;Lakshmi Uppu, Jaya;Godugu, Chandraiah;Shankaraiah, Nagula;Kamal, Ahmed published 《Synthesis and biological evaluation of substituted N-(2-(1H-benzo[d]imidazol-2-yl)phenyl)cinnamides as tubulin polymerization inhibitors》 in 2020. The article was appeared in 《Bioorganic Chemistry》. They have made some progress in their research.COA of Formula: C13H11N3 The article mentions the following:

A new series of N-(2-(1H-benzo[d]imidazol-2-yl)phenyl) cinnamides I [R = H, 4-CH₃, 4-F, etc.; R¹ = H, 4-NO₂, 4-Br, etc.] was prepared and evaluated for their in-vitro cytotoxic activity using various cancer cell lines viz.A549 (human non-small cell lung cancer), MDA-MB-231 (human triple neg. breast cancer), B16-F10 (mouse melanoma), BT-474 (human breast cancer), and 4 T1 (mouse triple neg. breast cancer). In the series of tested compounds, I [R = 4-CH₃ ; R¹ = 4-OC₂H₅] showed potent cytotoxic activity against non-small cell lung cancer cell line with IC₅₀ value of 0.29 ± 0.02μM. The cytotoxicity of most potent compound I [R = 4-CH₃ ; R¹ = 4-OC₂H₅] was also tested on NRK-52E (normal rat kidney epithelial cell line) and showed less cytotoxicity compared to cancer cells. Tubulin polymerization assay indicated that the I [R = 4-CH₃ ; R¹ = 4-OC₂H₅] was able to impede the cell division by inhibiting tubulin polymerization Moreover, mol. docking study also suggested the binding of I [R = 4-CH₃ ; R¹ = 4-OC₂H₅] at the colchicine-binding site of the tubulin protein. Cell cycle anal. revealed that the I [R = 4-CH₃ ; R¹ = 4-OC₂H₅] arrests G2/M phase. In addition, I [R = 4-CH₃ ; R¹ = 4-OC₂H₅] induced apoptosis in A549 cell lines was evaluated by various staining studies like acridine orange, DAPI, anal. of mitochondrial membrane potential, annexin V-FITC, and DCFDA assays. The experimental procedure involved many compounds, such as 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 COA of Formula: C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem