Related Products of 693-98-1, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 693-98-1 as follows.
PREPARATION 75 4,5-Diiodo-2-methylimidazole STR156 A solution of iodine monochloride (32.5 g) dissolved in dichloromethane (100 cm3) was added dropwise over 1.5 hours to a solution of 2-methylimidazole (8.2 g) and triethylamine (20. 2 g) in dichloromethane (200 cm3) at -70¡ã under nitrogen. The mixture was stirred for a further 30 minutes, warmed to -30¡ã, and then poured into water (200 cm3). The resulting precipitate was filtered off, dried and recrystallized from ethyl acetate-hexane to afford 4,5-diiodo-2-methylimidazole (18.5 g) which was characterised spectroscopically and used directly without further purification.
According to the analysis of related databases, 693-98-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Pfizer Inc.; US4728653; (1988); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem