Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 693-98-1, name is 2-Methyl-1H-imidazole, A new synthetic method of this compound is introduced below., HPLC of Formula: C4H6N2
Add 1 mol of 2-methylimidazole to a 250 ml three-neck round bottom flask,1.2 mol of acrylonitrile and 150 ml of anhydrous methanol,Obtaining a mixture; under the protection of a nitrogen atmosphere,The above mixture was stirred and refluxed at 60 C for 14 hours.The reaction product was obtained; after the reaction was stopped, unreacted acrylonitrile and a solvent were removed by rotary evaporation, and the treated reaction product was vacuum dried at 60 C for 24 hours.A yellow transparent liquid is obtained which is 1-nitrileethyl-2-methylimidazole.The yield was 83%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Hebei University of Technology; Zhang Wenlin; Huo Yu; Zhao Yongqi; Lan Xiaoyan; Shi Ziwei; Sun Tengfei; Li Gongwei; Li Chunli; (13 pag.)CN108586348; (2018); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem